Promoting the Social-emotional Wellbeing of Infants and Toddlers in Early Intervention Programs: Promising Strategies in Four Communities

This brief presents promising approaches to support the social-emotional wellbeing of infants and toddlers through the Part C Program. The strategies discussed in this brief were identified through case studies carried out in four communities: Boston, Massachusetts; Los Angeles County, California; Doña Ana County, New Mexico; and Southeast Kansas. These case studies were part of a larger project designed to show different policy options that states use to support strategies that target social-emotional development as part of a comprehensive approach to early intervention services. The project included a 50-state survey of Part C Program coordinators, the individuals who are responsible for administering the Part C Program in compliance with federal and state requirements. Findings from this survey are reported in Promoting Social-Emotional Wellbeing in Early Intervention Services: A Fifty State View. As a companion to the survey report, this brief examines exemplary policies and practices that highlight the potential of the Part C Early Intervention Program to play a major role in reducing the risk of long-term social-emotional and behavioral difficulties of vulnerable children

Promoting Young Children's Health and Development: Taking Stock of State Policies

Young children's health is essential to their overall development, well-being, and school readiness. Untreated health problems and a lack of preventive care contribute to higher rates of serious illness, absenteeism in preschool, physical and emotional distress, and even long-term disability. At a historic moment when the passage of federal health care reform promises significant improvements in health care access for many Americans, it is important to take stock of how well states are currently meeting the health needs of young children in low-income families. This brief presents information from NCCP's Improving the Odds for Young Children project about state policy choices in the following areas that affect the health and well-being of children, ages birth to 5: access to health care and continuity of care; maternal health care; and preventive screening and assessment. Relevant components of health care reform legislation are considered in a set of recommendations for meeting the short and long-term health care needs of young, low-income children

HI Properties of Low Luminosity Star-Forming Galaxies in the KPNO International Spectroscopic Survey

New HI observations are presented for a complete sample of 109 low luminosity star-forming galaxies taken from the KPNO International Spectroscopic Survey (KISS), the first CCD-based wide-field objective-prism survey for emission-line galaxies. This sample consists of all star-forming galaxies with M_B > -18.0 and cz < 11,000 km/s from the first Halpha-selected survey list. Overall, 97 out of 109 galaxies have been detected in HI. We confirm the weak trend of increasing gas richness with decreasing luminosity found by previous authors. Gas richness is also shown to be weakly anti-correlated with metallicity. The dependence of star formation rates (SFRs) and HI gas depletion timescales on metallicity is examined. The median solar metallicity based SFR and gas depletion timescale are 0.1639 M_sun/yr and 5 Gyrs, respectively. Corrections for variations in metallicity decreases SFRs by about 0.5 dex and increases gas depletion timescales by an average of about 8 Gyrs. The majority of galaxies in this sample still have large reservoirs of HI gas, and despite their large current star formation rates, could have formed stars in a quasi-continuous manner for a Hubble time. Finally, we present the first HI mass function for low luminosity star-forming galaxies and show that this subpopulation contributes 10-15% of the overall HI density in the local universe. We conclude that if the HI mass function of the Universe does indeed have a steeply rising low-mass slope as suggested by previous authors, it is not due to the population of low luminosity star-forming galaxies.Comment: 27 pages, 13 figures, 4 tables. Accepted for publication in the Astronomical Journa

Valsalva maneuver: Insights into baroreflex modulation of human sympathetic activity

Valsalva's maneuver, voluntary forced expiration against a closed glottis, is a well-characterized research tool, used to assess the integrity of human autonomic cardiovascular control. Valsalva straining provokes a stereotyped succession of alternating positive and negative arterial pressure and heart rate changes mediated in part by arterial baroreceptors. Arterial pressure changes result primarily from fluctuating levels of venous return to the heart and changes of sympathetic nerve activity. Muscle sympathetic activity was measured directly in nine volunteers to explore quantitatively the relation between arterial pressure and human sympathetic outflow during pressure transients provoked by controlled graded Valsalva maneuvers. Our results underscore several properties of sympathetic regulation during Valsalva straining. First, muscle sympathetic nerve activity changes as a mirror image of changes in arterial pressure. Second, the magnitude of sympathetic augmentation during Valsalva straining predicts phase 4 arterial pressure elevations. Third, post-Valsalva sympathetic inhibition persists beyond the return of arterial and right atrial pressures to baseline levels which reflects an alteration of the normal relation between arterial pressure and muscle sympathetic activity. Therefore, Valsalva straining may have some utility for investigating changes of reflex control of sympathetic activity after space flight; however, measurement of beat-to-beat arterial pressure is essential for this use. The utility of this technique in microgravity can not be determined from these data. Further investigations are necessary to determine whether these relations are affected by the expansion of intrathoracic blood volume associated with microgravity

Influence of Reproductive and Environmental Factors on Population Size .. of Wild Hyacinth [Camassia angusta (Engelm.· and A. Gray) Blank. (Liliaceae)], an Illinois Endangered Species

Wild hyacinth (Camassia angusta) is a perennial species native to mesic prairies of the midwestern and south-central United States. In Illinois, the only extant population of this state-endangered species is in a small section of degraded black-soil prairie along a railroad track right-of-way south of Elwin, Macon County. The objectives of this study were to determine the population status, seed production, and effects of scarification and stratification on germination of C. angusta. The population was surveyed from 1990 to 2007. A survey of other plant species present was conducted in 1999. The site consisted of approximately 75% native and 25% exotic species. The number of flowering stems of Camassia angusta fluctuated significantly (28 to 169 plants) during the course of this study. Prescribed spring burns and a construction equipment disturbance may be partially responsible for these fluctuations. A large percentage of undeveloped fruit, resulting in low seed production ( \u3c3,000), as well as low seed germination (8%), may be responsible for this population\u27s inability to increase consistently in number of individuals

Strength in diversity: enhancing learning in vocationally-orientated, master's level courses

Postgraduate education in geography, especially at the Master’s level, is undergoing significant changes in the developed world. There is an expansion of vocationally-oriented degree programmes, increasing recruitment of international students, integration of work place skills, and the engagement of non-traditional postgraduate students as departments respond to policies for a more ‘inclusive’ higher education. This paper sets the context by outlining some programmatic changes in selected countries (Australia, the UK, and the USA). We briefly reflect on how postgraduate ‘bars’ or ‘levels’ are defined and explore in detail what ‘diversity’ or ‘heterogeneity’ means in these new postgraduate settings. The paper then explores some examples of practice drawn from our own experiences, whilst recognising that relevance will vary in other contexts. Finally we consider how diversity can be harnessed as a strength that has potential to enhance taught elements of contemporary postgraduate education in and beyond the discipline

Binocular deficits associated with early alternating monocular defocus. II. Neurophysiological observations

Experiencing binocularly conflicting signals early in life dramatically alters the binocular responses of cortical neurons. Because visual cortex is highly plastic during a critical period of development, cortical deficits resulting from early abnormal visual experience often mirror the nature of interocular decorrelation of neural signals from the two eyes. In the preceding paper, we demonstrated that monkeys that experienced early alternating monocular defocus (-1.5, -3.0, or -6.0 D) show deficits in stereopsis that generally reflected the magnitude of imposed monocular defocus. Because these results indicated that alternating monocular defocus affected the higher spatial frequency components of visual scenes more severely, we employed microelectrode recording methods to investigate whether V1 neurons in these lens-reared monkeys exhibited spatial-frequency-dependent alterations in their binocular response properties. We found that a neuron\u27s sensitivity to interocular spatial phase disparity was reduced in the treated monkeys and that this reduction was generally more severe for units tuned to higher spatial frequencies. In the majority of the affected units, the disparity-sensitivity loss was associated with interocular differences in monocular receptive field properties. The present results suggest that the behavioral deficits in stereopsis produced by abnormal visual experience reflect at least in part the constraints imposed by alterations at the earliest stages of binocular cortical processing and support the hypothesis that the local disparity processing mechanisms in primates are spatially tuned and can be independently compromised by early abnormal visual experience

Early monocular defocus disrupts the normal development of receptive-field structure in V2 neurons of macaque monkeys

Experiencing different quality images in the two eyes soon after birth can cause amblyopia, a developmental vision disorder. Amblyopic humans show the reduced capacity for judging the relative position of a visual target in reference to nearby stimulus elements (position uncertainty) and often experience visual image distortion. Although abnormal pooling of local stimulus information by neurons beyond striate cortex (V1) is often suggested as a neural basis of these deficits, extrastriate neurons in the amblyopic brain have rarely been studied using microelectrode recording methods. The receptive field (RF) of neurons in visual area V2 in normal monkeys is made up of multiple subfields that are thought to reflect V1 inputs and are capable of encoding the spatial relationship between local stimulus features. We created primate models of anisometropic amblyopia and analyzed the RF subfield maps for multiple nearby V2 neurons of anesthetized monkeys by using dynamic two-dimensional noise stimuli and reverse correlation methods. Unlike in normal monkeys, the subfield maps of V2 neurons in amblyopic monkeys were severely disorganized: subfield maps showed higher heterogeneity within each neuron as well as across nearby neurons. Amblyopic V2 neurons exhibited robust binocular suppression and the strength of the suppression was positively correlated with the degree of hereogeneity and the severity of amblyopia in individual monkeys. Our results suggest that the disorganized subfield maps and robust binocular suppression of amblyopic V2 neurons are likely to adversely affect the higher stages of cortical processing resulting in position uncertainty and image distortion

Cortical effects of brief daily periods of unrestricted vision during early monocular form deprivation

Experiencing daily brief periods of unrestricted vision during early monocular form deprivation prevents or reduces the degree of resulting amblyopia. To gain insight into the neural basis for these protective effects, we analyzed the monocular and binocular response properties of individual neurons in the primary visual cortex (V1) of macaque monkeys that received intermittent unrestricted vision. Microelectrode-recording experiments revealed significant decreases in the proportion of units that were dominated by the treated eyes, and the magnitude of this ocular dominance imbalance was correlated with the degree of amblyopia. The sensitivity of V1 neurons to interocular spatial phase disparity was significantly reduced in all treated monkeys compared with normal adults. With unrestricted vision, however, there was a small but significant increase in overall disparity sensitivity. Binocular suppression was prevalent in monkeys with constant form deprivation but significantly reduced by the daily periods of unrestricted vision. If neurons exhibited consistent responses to stimulation of the treated eye, monocular response properties obtained by stimulation of the two eyes were similar. These results suggest that the observed protective effects of brief periods of unrestricted vision are closely associated with the ability of V1 neurons to maintain their functional connections from the deprived eye and that interocular suppression in V1 may play an important role in regulating synaptic plasticity of these monkeys