182 research outputs found

    Net precipitation over the Baltic Sea for one year using several methods

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    Precipitation and evaporation over the Baltic Sea are calculated for a one-year period from September 1998 to August 1999 by four different tools, the two atmospheric regional models HIRLAM and REMO, the oceanographic model PROBE-Baltic in combination with the SMHI (1 × 1)° database and Interpolated Fields, based essentially on ship measurements. The investigated period is slightly warmer and wetter than the climatological mean. Correlation coefficients of the differently calculated latent heat fluxes vary between 0.81 (HIRLAM and REMO) and 0.56 (SMHI/PROBE-Baltic and Interpolated Fields), while the correlation coefficients between model fluxes and measured fluxes range from 0.61 and 0.78. Deviations of simulated and interpolated monthly precipitation over the Baltic Sea are less than ±5 mm in the southern Baltic and up to 20 mm near the Finnish coast for the one-year period. The methods simulate the annual cycle of precipitation and evaporation of the Baltic Proper in a similar manner with a broad maximum of net precipitation in spring and early summer and a minimum in late summer. The annual averages of net precipitation of the Baltic Proper range from 57 mm (REMO) to 262 mm (HIRLAM) and for the Baltic Sea from 96 mm (SMHI/PROBE-Baltic) to 209 mm (HIRLAM). This range is considered to give the uncertainty of present-day determination of the net precipitation over the Baltic Sea

    FluoroSpot Analysis of TLR-Activated Monocytes Reveals Several Distinct Cytokine-Secreting Subpopulations

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    Monocytes have long been considered a heterogeneous group of cells both in terms of morphology and function. In humans, three distinct subsets have been described based on their differential expression of the cell surface markers CD14 and CD16. However, the relationship between these subsets and the production of cytokines has for the most part been based on ELISA measurements, making it difficult to draw conclusions as to their functional profile on the cellular level. In this study, we have investigated lipoteichoic acid (LTA)- and lipopolysaccharide (LPS)-induced cytokine secretion by monocytes using the FluoroSpot technique. This method measures the number of cytokine-secreting cells on the single-cell level and uses fluorescent detection, allowing for the simultaneous analysis of two cytokines from the same population of isolated cells. By this approach, human monocytes from healthy volunteers could be divided into several subgroups as IL-1β, IL-6, TNF-α and MIP-1β were secreted by larger populations of responding cells (25.9–39.2%) compared with the smaller populations of GM-CSF (9.1%), IL-10 (1.3%) and IL-12p40 (1.2%). Furthermore, when studying co-secretion in FluoroSpot, an intricate relationship between the monocytes secreting IL-1β and/or IL-6 and those secreting TNF-α, MIP-1β, GM-CSF, IL-10 and IL-12p40 was revealed. In this way, dissecting the secretion pattern of the monocytes in response to TLR-2 or TLR-4 stimulation, several subpopulations with distinct cytokine-secreting profiles could be identified

    Revisiting the Local Scaling Hypothesis in Stably Stratified Atmospheric Boundary Layer Turbulence: an Integration of Field and Laboratory Measurements with Large-eddy Simulations

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    The `local scaling' hypothesis, first introduced by Nieuwstadt two decades ago, describes the turbulence structure of stable boundary layers in a very succinct way and is an integral part of numerous local closure-based numerical weather prediction models. However, the validity of this hypothesis under very stable conditions is a subject of on-going debate. In this work, we attempt to address this controversial issue by performing extensive analyses of turbulence data from several field campaigns, wind-tunnel experiments and large-eddy simulations. Wide range of stabilities, diverse field conditions and a comprehensive set of turbulence statistics make this study distinct

    Stroke and plasma markers of milk fat intake – a prospective nested case-control study

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    <p>Abstract</p> <p>Background</p> <p>Dairy products are high in saturated fat and are traditionally a risk factor for vascular diseases. The fatty acids 15:0 and 17:0 of plasma lipids are biomarkers of milk fat intake. The aim of the present study was to evaluate the risk of a first-ever stroke in relation to the plasma milk fat biomarkers.</p> <p>Methods</p> <p>A prospective case-control study was nested within two population based health surveys in Northern Sweden. Among 129 stroke cases and 257 matched controls, plasma samples for fatty acid analyses were available in 108 cases and 216 control subjects. Proportions of 15:0 and 17:0 of plasma lipids, weight, height, blood lipids, blood pressures, and lifestyle data were employed in conditional logistic regression modelling.</p> <p>Results</p> <p>The proportions of fatty acids 17:0 and 15:0+17:0 of total plasma phospholipids were significantly higher in female controls than cases, but not in men. 17:0 and 15:0+17:0 were significantly and inversely related to stroke in the whole study sample as well as in women. The standardised odds ratio (95% CI) in women to have a stroke was 0.41 (0.24–0.69) for 17:0 in plasma phospholipids. Adjustment for traditional cardiovascular risk factors, physical activity and diet had marginal effects on the odds ratios. A similar, but non-significant, trend was seen in men.</p> <p>Conclusion</p> <p>It is hypothesised that dairy or milk fat intake may be inversely related to the risk of a first event of stroke. The intriguing results of this study should be interpreted with caution. Follow up studies with greater power, and where intakes are monitored both by dietary recordings and fatty acid markers are needed.</p

    Greenhouse gas emissions of realistic dietary choices in Denmark: the carbon footprint and nutritional value of dairy products

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    Background: Dairy products are important in a healthy diet due to their high nutritional value; they are, however, associated with relatively large greenhouse gas emissions (GHGE) per kg product. When discussing the need to reduce the GHGE caused by the food system, it is crucial to consider the nutritional value of alternative food choices. Objective: The objective of this study was to elucidate the role of dairy products in overall nutrition and to clarify the effects of dietary choices on GHGE, and to combine nutritional value and GHGE data. Methods: We created eight dietary scenarios with different quantity of dairy products using data from the Danish National Dietary Survey (1995–2006). Nutrient composition and GHGE data for 71 highly consumed foods were used to estimate GHGE and nutritional status for each dietary scenario. An index was used to estimate nutrient density in relation to nutritional recommendation and climate impact for solid food items; high index values were those with the highest nutrient density scores in relation to the GHGE. Results: The high-dairy scenario resulted in 27% higher protein, 13% higher vitamin D; 55% higher calcium; 48% higher riboflavin; and 18% higher selenium than the non-dairy scenario. There was a significant correlation between changes in calcium and changes in vitamin D, selenium, and riboflavin content (P=0.0001) throughout all of the diets. The estimated GHGE for the dietary scenario with average-dairy consumption was 4,631 g CO2e/day. Conclusions: When optimizing a diet with regard to sustainability, it is crucial to account for the nutritional value and not solely focus on impact per kg product. Excluding dairy products from the diet does not necessarily mitigate climate change but in contrast may have nutritional consequences

    Scalar flux profile relationships over the open ocean

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    Author Posting. © American Geophysical Union, 2004. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research 109 (2004): C08S09, doi:10.1029/2003JC001960.The most commonly used flux-profile relationships are based on Monin-Obukhov (MO) similarity theory. These flux-profile relationships are required in indirect methods such as the bulk aerodynamic, profile, and inertial dissipation methods to estimate the fluxes over the ocean. These relationships are almost exclusively derived from previous field experiments conducted over land. However, the use of overland measurements to infer surface fluxes over the ocean remains questionable, particularly close to the ocean surface where wave-induced forcing can affect the flow. This study investigates the flux profile relationships over the open ocean using measurements made during the 2000 Fluxes, Air-Sea Interaction, and Remote Sensing (FAIRS) and 2001 GasEx experiments. These experiments provide direct measurement of the atmospheric fluxes along with profiles of water vapor and temperature. The specific humidity data are used to determine parameterizations of the dimensionless gradients using functional forms of two commonly used relationships. The best fit to the Businger-Dyer relationship [ Businger, 1988 ] is found using an empirical constant of a q = 13.4 ± 1.7. The best fit to a formulation that has the correct form in the limit of local free convection [e.g., Wyngaard, 1973 ] is found using a q = 29.8 ± 4.6. These values are in good agreement with the consensus values from previous overland experiments and the Coupled Ocean-Atmosphere Response Experiment (COARE) 3.0 bulk algorithm [ Fairall et al., 2003 ]; e.g., the COARE algorithm uses empirical constants of 15 and 34.2 for the Businger-Dyer and convective forms, respectively. Although the flux measurements were made at a single elevation and local similarity scaling is applied, the good agreement implies that MO similarity is valid within the marine atmospheric surface layer above the wave boundary layer.The FAIRS work was supported by the Office of Naval Research grant N00014-00-1-0403 while the GasEx work was supported by the National Science Foundation grant OCE-9986724
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