555 research outputs found
A Rare Case of Effusive Constrictive Cholesterol Pericarditis: A Case Report and Review
Effusive constrictive cholesterol pericarditis is exceedingly rare. Most cases have an unclear etiology but can be associated with rheumatoid arthritis, tuberculosis infection, and hypothyroidism. The hallmark of the effusion is the distinctively high levels of cholesterol. We present the case of a 68-year-old male with prolonged symptoms of dyspnea with associated moderate pericardial effusion that were later determined to be constrictive effusive etiology, and the patient was referred for stripping with pathologic cholesterol crystal formation on pathology review
The effect of dietary fish oil on weight gain and insulin sensitivity is dependent on APOE genotype in humanized targeted replacement mice
We investigated the independent and interactive impact of the common APOE genotype and marine n-3 polyunsaturated fatty acids (PUFA) on the development of obesity and associated cardiometabolic dysfunction in a murine model. Human APOE3 and APOE4 targeted replacement mice were fed either a high-fat control diet (HFD) or a HFD supplemented with 3% n-3 PUFA from fish oil (HFD + FO) for 8 wk. We established the impact of intervention on food intake, bodyweight, and visceral adipose tissue (VAT) mass; plasma, lipids (cholesterol and triglycerides), liver enzymes, and adipokines; glucose and insulin during an intraperitoneal glucose tolerance test; and Glut4 and ApoE expression in VAT. HFD feeding induced more weight gain and higher plasma lipids in APOE3 compared to APOE4 mice (P < 0.05), along with a 2-fold higher insulin and impaired glucose tolerance. Supplementing APOE3, but not APOE4, animals with dietary n-3 PUFA decreased bodyweight gain, plasma lipids, and insulin (P < 0.05) and improved glucose tolerance, which was associated with increased VAT Glut4 mRNA levels (P < 0.05). Our findings demonstrate that an APOE3 genotype predisposes mice to develop obesity and its metabolic complications, which was attenuated by n-3 PUFA supplementation.—Slim, K. E., Vauzour, D., Tejera, N., Voshol, P. J., Cassidy, A., Minihane, A. M. The effect of dietary fish oil on weight gain and insulin sensitivity is dependent on APOE genotype in humanized targeted replacement mice
Effecten van verschillen in mestsoort en waterstand op vegetatie en fauna van klei-op-veen graslanden in de Alblasserwaard
Tracking beats and microtiming in Afro-Latin American music using conditional random fields and deep learning
Trabajo presentado en ISMIR 2019 : 20th Conference of the International Society for Music Information Retrieval, Delft, Netherlands, 4-8 nov, 2019PostprintEvents in music frequently exhibit small-scale temporal deviations (microtiming), with respect to the underlying regular metrical grid. In some cases, as in music from the Afro-Latin American tradition, such deviations appear systematically, disclosing their structural importance in rhythmic and stylistic configuration. In this work we explore the idea of automatically and jointly tracking beats and microtiming in timekeeper instruments of Afro-Latin American music, in particular Brazilian samba and Uruguayan candombe. To that end, we propose a language model based on conditional random fields that integrates beat and onset likelihoods as observations. We derive those activations using deep neural networks and evaluate its performance on manually annotated data using a scheme adapted to this task. We assess our approach in controlled conditions suitable for these timekeeper instruments, and study the microtiming profiles’ dependency on genre and performer, illustrating promising aspects of this technique towards a more comprehensive understanding of these music traditions
Is markerless acquisition of speech production accurate ?
International audienceIn this study, the precision of markerless acquisition techniques have been assessed when used to acquire articulatory data for speech production studies. Two different markerless systems have been evaluated and compared to a marker-based one. The main finding is that both markerless systems provide reasonable result during normal speech and the quality is uneven during fast articulated speech. The quality of the data is dependent on the temporal resolution of the markerless system
Phase Measurement for Driven Spin Oscillations in a Storage Ring
This paper reports the first simultaneous measurement of the horizontal and
vertical components of the polarization vector in a storage ring under the
influence of a radio frequency (rf) solenoid. The experiments were performed at
the Cooler Synchrotron COSY in J\"ulich using a vector polarized, bunched
deuteron beam. Using the new spin feedback system, we
set the initial phase difference between the solenoid field and the precession
of the polarization vector to a predefined value. The feedback system was then
switched off, allowing the phase difference to change over time, and the
solenoid was switched on to rotate the polarization vector. We observed an
oscillation of the vertical polarization component and the phase difference.
The oscillations can be described using an analytical model. The results of
this experiment also apply to other rf devices with horizontal magnetic fields,
such as Wien filters. The precise manipulation of particle spins in storage
rings is a prerequisite for measuring the electric dipole moment (EDM) of
charged particles
Spin tune mapping as a novel tool to probe the spin dynamics in storage rings
Precision experiments, such as the search for electric dipole moments of
charged particles using storage rings, demand for an understanding of the spin
dynamics with unprecedented accuracy. The ultimate aim is to measure the
electric dipole moments with a sensitivity up to 15 orders in magnitude better
than the magnetic dipole moment of the stored particles. This formidable task
requires an understanding of the background to the signal of the electric
dipole from rotations of the spins in the spurious magnetic fields of a storage
ring. One of the observables, especially sensitive to the imperfection magnetic
fields in the ring is the angular orientation of stable spin axis. Up to now,
the stable spin axis has never been determined experimentally, and in addition,
the JEDI collaboration for the first time succeeded to quantify the background
signals that stem from false rotations of the magnetic dipole moments in the
horizontal and longitudinal imperfection magnetic fields of the storage ring.
To this end, we developed a new method based on the spin tune response of a
machine to artificially applied longitudinal magnetic fields. This novel
technique, called \textit{spin tune mapping}, emerges as a very powerful tool
to probe the spin dynamics in storage rings. The technique was experimentally
tested in 2014 at the cooler synchrotron COSY, and for the first time, the
angular orientation of the stable spin axis at two different locations in the
ring has been determined to an unprecedented accuracy of better than
rad.Comment: 32 pages, 15 figures, 7 table
Phase locking the spin precession in a storage ring
This letter reports the successful use of feedback from a spin polarization
measurement to the revolution frequency of a 0.97 GeV/ bunched and polarized
deuteron beam in the Cooler Synchrotron (COSY) storage ring in order to control
both the precession rate ( kHz) and the phase of the horizontal
polarization component. Real time synchronization with a radio frequency (rf)
solenoid made possible the rotation of the polarization out of the horizontal
plane, yielding a demonstration of the feedback method to manipulate the
polarization. In particular, the rotation rate shows a sinusoidal function of
the horizontal polarization phase (relative to the rf solenoid), which was
controlled to within a one standard deviation range of rad. The
minimum possible adjustment was 3.7 mHz out of a revolution frequency of 753
kHz, which changes the precession rate by 26 mrad/s. Such a capability meets a
requirement for the use of storage rings to look for an intrinsic electric
dipole moment of charged particles
The influence of Mechanical bowel preparation in elective colorectal surgery for diverticulitis
Background: Mechanical bowel preparation (MBP) has been shown to have no influence on the incidenc
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