Connections of the Mesencephalic Locomotor Region (MLR) in the Cat

The cat entopeduncular nucleus (EN), which is the main output of the basal ganglia, is known to project to the mesencephalic tegmentum. We have been able to elicit antidromic responses in single EN neurons from the region of the mesencephalic locomotor region (MLR), then transect (precollicular-postmamillary) the brainstem and elicit rhythmic movements of the limbs by stimulation of the same site in the same animal. Injections of the fluorescent dye 2,4 diamidino phenylindole 2 HCL (DAPI) into this area induces retrograde labeling of cell bodies in EN and motor cortex. Injections of a tritiated amino acid (leucine) into the motor cortex induce terminal labeling in the area of the MLR. These studies describe convergent projections from EN and motor cortex to the MLR. These connections may be involved in the sequencing and ordering of voluntary movements in which locomotion is necessary

Io: IUE observations of its atmosphere and the plasma torus

Two of the main components of the atmosphere of Io, neutral oxygen and sulfur, were detected with the IUE. Four observations yield brightnesses that are similar, regardless of whether the upstream or the downstream sides of the torus plasma flow around Io is observed. A simple model requires the emissions to be produced by the interaction of O and S columns in the exospheric range with 2 eV electrons. Cooling of the 5 eV torus electrons is required prior to their interaction with the atmosphere of Io. Inconsistencies in the characteristics of the spectra that cannot be accounted for in this model require further analysis with improved atomic data. The Io plasma torus was monitored with the IUE. The long-term stability of the warm torus is established. The observed brightnesses were analyzed using a model of the torus, and variations of less than 30 percent in the composition are observed, the quantitative results being model dependent

Can we predict the duration of an interglacial?

Differences in the duration of interglacials have long been apparent in palaeoclimate records of the Late and Middle Pleistocene. However, a systematic evaluation of such differences has been hampered by the lack of a metric that can be applied consistently through time and by difficulties in separating the local from the global component in various proxies. This, in turn, means that a theoretical framework with predictive power for interglacial duration has remained elusive. Here we propose that the interval between the terminal oscillation of the bipolar seesaw and three thousand years (kyr) before its first major reactivation provides an estimate that approximates the length of the sea-level highstand, a measure of interglacial duration. We apply this concept to interglacials of the last 800 kyr by using a recently-constructed record of interhemispheric variability. The onset of interglacials occurs within 2 kyr of the boreal summer insolation maximum/precession minimum and is consistent with the canonical view of Milankovitch forcing pacing the broad timing of interglacials. Glacial inception always takes place when obliquity is decreasing and never after the obliquity minimum. The phasing of precession and obliquity appears to influence the persistence of interglacial conditions over one or two insolation peaks, leading to shorter (~ 13 kyr) and longer (~ 28 kyr) interglacials. Glacial inception occurs approximately 10 kyr after peak interglacial conditions in temperature and CO2, representing a characteristic timescale of interglacial decline. Second-order differences in duration may be a function of stochasticity in the climate system, or small variations in background climate state and the magnitude of feedbacks and mechanisms contributing to glacial inception, and as such, difficult to predict. On the other hand, the broad duration of an interglacial may be determined by the phasing of astronomical parameters and the history of insolation, rather than the instantaneous forcing strength at inception

Topological Twistons in Crystalline Polyethylene

We introduce an alternate model to describe twistons in crystalline polyethylene. The model couples torsional and longitudinal degrees of freedom and appears as an extension of a model that describes only the torsional motion. We find exact solutions that describe stable topological twistons, in good agreement with the torsional and longitudinal interactions in polyethylene.Comment: Latex, 10 pages; some stylistic corrections, to appear in Chemical Physics Letter

The High Energy Telescope on EXIST

The Energetic X-ray Imaging Survey Telescope (EXIST) is a proposed next generation multi-wavelength survey mission. The primary instrument is a High Energy telescope (HET) that conducts the deepest survey for Gamma-ray Bursts (GRBs), obscured-accreting and dormant Supermassive Black Holes and Transients of all varieties for immediate followup studies by the two secondary instruments: a Soft X-ray Imager (SXI) and an Optical/Infrared Telescope (IRT). EXIST will explore the early Universe using high redshift GRBs as cosmic probes and survey black holes on all scales. The HET is a coded aperture telescope employing a large array of imaging CZT detectors (4.5 m^2, 0.6 mm pixel) and a hybrid Tungsten mask. We review the current HET concept which follows an intensive design revision by the HET imaging working group and the recent engineering studies in the Instrument and Mission Design Lab at the Goddard Space Flight Center. The HET will locate GRBs and transients quickly (<10-30 sec) and accurately (< 20") for rapid (< 1-3 min) onboard followup soft X-ray and optical/IR (0.3-2.2 micron) imaging and spectroscopy. The broad energy band (5-600 keV) and the wide field of view (~90 deg x 70 deg at 10% coding fraction) are optimal for capturing GRBs, obscured AGNs and rare transients. The continuous scan of the entire sky every 3 hours will establish a finely-sampled long-term history of many X-ray sources, opening up new possibilities for variability studies.Comment: 10 pages, 6 figures, 3 tables, SPIE conference proceedings (UV, X-ray, and Gamma-Ray Space Instrumentation for Astronomy XVI, 7435-9

Low-cost wave characterization modules for oil spill response

Marine oil spills can be remediated by mechanical skimmers in calm waters, but performance degrades with increased wave height. We have developed and demonstrated a system that quantifies local wave characteristics with an uncertainty of four inches of heave. Our system is intended for the measurement of wave characteristics during oil spill recovery. It conveys this information to coordinators and responders in real time via WiFi and remote reporting through a satellite network. This information will allow for enhanced situational awareness during an oil spill response, assisting stakeholders and optimizing mechanical skimming operations. Our wave characterization module (WCM) uses accelerometer outputs from a very small inertial measurement unit (IMU) to generate wave statistics and calculate wave characteristics. It is configured such that a WCM can either be attached to a skimmer float or incorporated into a microbuoy. Wave height and period are transmitted via WiFi and/or a satellite-enabled mesh-grid network to a cloud-hosted geographic information system (GIS). Here, we discuss the bare-bones sensors-plus-algorithm approach we developed by using spring-mass systems to approximate the wave height and period regime of interest. We then describe open water tests carried out using that development system both mounted to a weir skimmer mockup and packaged in a microbuoy. Finally, we present controlled tests in the wave tank at Ohmsett, the National Oil Spill Response Test Facility in New Jersey, with the WCMs communicating the wave characteristics via WiFi to tankside laptops and via satellite to the cloud-based GIS. Snapshot determinations of wave height calculated using the scalar magnitude of the three-axis accelerometer in the IMU were within four inches of the benchmark wave measurement system at Ohmsett. (C) 2018 Shanghai Jiaotong University. This is an open access article under the CC BY-NC-ND license

Coulomb gap in the one-particle density of states in three-dimensional systems with localized electrons

The one-particle density of states (1P-DOS) in a system with localized electron states vanishes at the Fermi level due to the Coulomb interaction between electrons. Derivation of the Coulomb gap uses stability criteria of the ground state. The simplest criterion is based on the excitonic interaction of an electron and a hole and leads to a quadratic 1P-DOS in the three-dimensional (3D) case. In 3D, higher stability criteria, including two or more electrons, were predicted to exponentially deplete the 1P-DOS at energies close enough to the Fermi level. In this paper we show that there is a range of intermediate energies where this depletion is strongly compensated by the excitonic interaction between single-particle excitations, so that the crossover from quadratic to exponential behavior of the 1P-DOS is retarded. This is one of the reasons why such exponential depletion was never seen in computer simulations.Comment: 6 pages, 1 figur

A Single Circumbinary Disk in the HD 98800 Quadruple System

We present sub-arcsecond thermal infrared imaging of HD 98800, a young quadruple system composed of a pair of low-mass spectroscopic binaries separated by 0.8'' (38 AU), each with a K-dwarf primary. Images at wavelengths ranging from 5 to 24.5 microns show unequivocally that the optically fainter binary, HD 98800B, is the sole source of a comparatively large infrared excess upon which a silicate emission feature is superposed. The excess is detected only at wavelengths of 7.9 microns and longer, peaks at 25 microns, and has a best-fit black-body temperature of 150 K, indicating that most of the dust lies at distances greater than the orbital separation of the spectroscopic binary. We estimate the radial extent of the dust with a disk model that approximates radiation from the spectroscopic binary as a single source of equivalent luminosity. Given the data, the most-likely values of disk properties in the ranges considered are R_in = 5.0 +/- 2.5 AU, DeltaR = 13+/-8 AU, lambda_0 = 2(+4/-1.5) microns, gamma = 0+/-2.5, and sigma_total = 16+/-3 AU^2, where R_in is the inner radius, DeltaR is the radial extent of the disk, lambda_0 is the effective grain size, gamma is the radial power-law exponent of the optical depth, tau, and sigma_total is the total cross-section of the grains. The range of implied disk masses is 0.001--0.1 times that of the moon. These results show that, for a wide range of possible disk properties, a circumbinary disk is far more likely than a narrow ring.Comment: 11 page Latex manuscript with 3 postscript figures. Accepted for publication in Astrophysical Journal Letters. Postscript version of complete paper also available at http://www.hep.upenn.edu/PORG/web/papers/koerner00a.p

Game On? Smoking Cessation Through the Gamification of mHealth: A Longitudinal Qualitative Study

BACKGROUND: Finding ways to increase and sustain engagement with mHealth interventions has become a challenge during application development. While gamification shows promise and has proven effective in many fields, critical questions remain concerning how to use gamification to modify health behavior. OBJECTIVE: The objective of this study is to investigate how the gamification of mHealth interventions leads to a change in health behavior, specifically with respect to smoking cessation. METHODS: We conducted a qualitative longitudinal study using a sample of 16 smokers divided into 2 cohorts (one used a gamified intervention and the other used a nongamified intervention). Each participant underwent 4 semistructured interviews over a period of 5 weeks. Semistructured interviews were also conducted with 4 experts in gamification, mHealth, and smoking cessation. Interviews were transcribed verbatim and thematic analysis undertaken. RESULTS: Results indicated perceived behavioral control and intrinsic motivation acted as positive drivers to game engagement and consequently positive health behavior. Importantly, external social influences exerted a negative effect. We identified 3 critical factors, whose presence was necessary for game engagement: purpose (explicit purpose known by the user), user alignment (congruency of game and user objectives), and functional utility (a well-designed game). We summarize these findings in a framework to guide the future development of gamified mHealth interventions. CONCLUSIONS: Gamification holds the potential for a low-cost, highly effective mHealth solution that may replace or supplement the behavioral support component found in current smoking cessation programs. The framework reported here has been built on evidence specific to smoking cessation, however it can be adapted to health interventions in other disease categories. Future research is required to evaluate the generalizability and effectiveness of the framework, directly against current behavioral support therapy interventions in smoking cessation and beyond