5,457 research outputs found
Hedging Effectiveness around USDA Crop Reports
It is well documented that “unanticipated” information contained in USDA crop reports induces large price reactions in corn and soybean markets. Thus, a natural question that arises from this literature is: To what extent are futures hedges able to remove or reduce increased price risk around report release dates? This paper addresses this question by simulating daily futures returns, daily cash returns and daily hedged returns around report release dates for two storable commodities (corn and soybeans) in two market settings (North Central Illinois and Memphis Tennessee). Various risk measures, including “Value at Risk,” are used to determine hedging effectiveness, and “Analysis of Variance” is used to uncover the underlying factors that contribute to hedging effectiveness.Agribusiness, Research Methods/ Statistical Methods,
Structural Optimisation: Biomechanics of the Femur
A preliminary iterative 3D meso-scale structural model of the femur was
developed, in which bar and shell elements were used to represent trabecular
and cortical bone respectively. The cross-sectional areas of the bar elements
and the thickness values of the shell elements were adjusted over successive
iterations of the model based on a target strain stimulus, resulting in an
optimised construct. The predicted trabecular architecture, and cortical
thickness distribution showed good agreement with clinical observations, based
on the application of a single leg stance load case during gait. The benefit of
using a meso-scale structural approach in comparison to micro or macro-scale
continuum approaches to predictive bone modelling was achievement of the
symbiotic goals of computational efficiency and structural description of the
femur.Comment: Accepted by Engineering and Computational Mechanics (Proceedings of
the ICE
XMM-Newton Reflection Grating Spectrometer Observations of the Prototypical Starburst Galaxy M82
We present results from XMM-Newton Reflection Grating Spectrometer
observations of the prototypical starburst galaxy M82. These high resolution
spectra represent the best X-ray spectra to date of a starburst galaxy. A
complex array of lines from species over a wide range of temperatures is seen,
the most prominent being due to Lyman-alpha emission from abundant low Z
elements such as N, O, Ne, Mg and Si. Emission lines from Helium-like charge
states of the same elements are also seen in emission, as are strong lines from
the entire Fe-L series. Further, the OVII line complex is resolved and is seen
to be consistent with gas in collisional ionization equilibrium. Spectral
fitting indicates emission from a large mass of gas with a differential
emission measure over a range of temperatures (from 0.2 keV to 1.6 keV, peaking
at 0.7 keV), and evidence for super-solar abundances of several elements is
indicated. Spatial analysis of the data indicates that low energy emission is
more extended to the south and east of the nucleus than to the north and west.
Higher energy emission is far more centrally concentrated.Comment: 5 pages, 4 figures, MNRAS accepte
Pretransplant HLA typing revealed loss of heterozygosity in the major histocompatibility complex in a patient with acute myeloid leukemia
Introduction
Chromosomal abnormalities are frequent events in hematological malignancies. The degree of HLA compatibility between donor and recipient in hematopoietic stem cell transplantation is critical.
Purpose of the study
In this report, we describe an acute myeloid leukemia case with loss of heterozygosity (LOH) encompassing the entire HLA.
Materials and methods
HLA molecular typing was performed on peripheral blood (PB) and buccal swabs (BS). Chromosomal microarray analysis (CMA) was performed using a whole genome platform.
Results
Typing results on PB sample collected during blast crisis demonstrated homozygosity at the -A, -B, -C, -DR, and -DQ loci. A BS sample demonstrated heterozygosity at all loci. A subsequent PB sample drawn after count recovery confirmed heterozygosity. The CMA performed on PB samples collected during and after blast crisis revealed a large terminal region of copy-neutral LOH involving chromosome region 6p25.3p21.31, spanning approximately 35.9 Mb. The results of the CMA assay on sample collected after count recovery did not demonstrate LOH.
Conclusions
LOH at the HLA gene locus may significantly influence the donor search resulting in mistakenly choosing homozygous donors. We recommend confirming the HLA typing of recipients with hematological malignancies when homozygosity is detected at any locus by using BS samples, or alternatively from PB when remission is achieved
The prevalence of personality disorders in the community: a global systematic review and meta-analysis
Background
Personality disorders are now internationally recognised as a mental health priority. Nevertheless, there are no systematic reviews examining the global prevalence of personality disorders.
Aims
To calculate the worldwide prevalence of personality disorders and examine whether rates vary between high and low and middle-income countries (LAMICs).
Method
We systematically searched PsycINFO, MEDLINE, EMBASE and PubMed from 1980 to May 2018 to identify articles reporting personality disorder prevalence rates in community populations (PROSPERO registration number: CRD42017065094).
Results
Forty-six studies (from 21 different countries spanning six continents) satisfied inclusion criteria. The worldwide pooled prevalence of any personality disorder was 7.8 % (95% Confidence Intervals: 6.1-9.5). Rates were greater in high income (9.6%; 95% CI: 7.9-11.3%) compared with LAMI (4.3%; 95% CI =2.6-6.1%) countries. In univariate meta-regressions, significant heterogeneity was partly attributable to study design (two-stage versus one-stage assessment), county income (high versus LAMI) and interview administration (clinician versus trained graduate). In multiple meta-regression analysis, study design remained a significant predictor of heterogeneity. Global rates of Cluster-A, B and C personality disorders were 3.8 % (3.2, 4.4%), 2.8% (1.6, 3.7%) and 5.0% (4.2, 5.9%).
Conclusions
Personality disorders are prevalent globally. Nevertheless, pooled prevalence rates should be interpreted with caution due to high levels of heterogeneity. More large-scale studies with standardised methodologies are now needed to increase our understanding of population needs and regional variations
A metagenomic assessment of the bacteria associated with Lucilia sericata and Lucilia cuprina (Diptera: Calliphoridae)
Lucilia Robineau-Desvoidy (Diptera: Calliphoridae) is a blow fly genus of forensic, medical, veterinary, and agricultural importance. This genus is also famous because of its beneficial uses in maggot debridement therapy (MDT). Although the genus is of considerable economic importance, our knowledge about microbes associated with these flies and how these bacteria are horizontally and trans-generationally transmitted is limited. In this study, we characterized bacteria associated with different life stages of Lucilia sericata (Meigen) and Lucilia cuprina(Wiedemann) and in the salivary gland of L. sericata by using 16S rDNA 454 pyrosequencing. Bacteria associated with the salivary gland of L. sericata were also characterized using light and transmission electron microscopy (TEM). Results from this study suggest that the majority of bacteria associated with these flies belong to phyla Proteobacteria, Firmicutes, andBacteroidetes, and most bacteria are maintained intragenerationally, with a considerable degree of turnover from generation to generation. In both species, second-generation eggs exhibited the highest bacterial phylum diversity (20 % genetic distance) than other life stages. The Lucilia sister species shared the majority of their classified genera. Of the shared bacterial genera, Providencia, Ignatzschineria, Lactobacillus, Lactococcus, Vagococcus, Morganella, and Myroides were present at relatively high abundances. Lactobacillus, Proteus,Diaphorobacter, and Morganella were the dominant bacterial genera associated with a survey of the salivary gland of L. sericata. TEM analysis showed a sparse distribution of both Gram-positive and Gram-negative bacteria in the salivary gland of L. sericata. There was more evidence for horizontal transmission of bacteria than there was for trans-generational inheritance. Several pathogenic genera were either amplified or reduced by the larval feeding on decomposing liver as a resource. Overall, this study provides information on bacterial communities associated with different life stages of Lucilia and their horizontal and trans-generational transmission, which may help in the development of better vector-borne disease management and MDT methods
Water loss: A postharvest quality marker in apple storage
Apple fruit can be stored for long periods of time, especially with the use of controlled atmosphere storage, but like many fruits and vegetables are susceptible to water loss. Water loss can result in compromised appearance such as skin shriveling, as well as loss of firmness, and reduced saleable weight, which in turn affect the income of growers and other industry stakeholders. Preharvest factors that can influence water loss in apples during the postharvest period include climate, cultivar, fruit size, tree age, orchard practices, and harvest maturity. Postharvest factors such as the storage temperature, relative humidity, storage type, and duration can also affect water loss in apple fruit during storage. The mechanisms of cuticle biosynthesis in water permeance, the role of stomata and lenticels, microcracking, crosstalk with mechanical injuries, storage disorders, and decay incidence during the storage of apples are reviewed. Additionally, the review summarizes: preharvest and postharvest factors influencing water loss; recent management strategies including pre-cooling, cold storage, controlled atmospheres, packaging, and anti-senescence chemicals; the use of edible coatings, as well as other non-chemical approaches for modulating water loss and maintaining storage quality. The review also provides direction for the industry to manage this destructive problem in the postharvest supply chain of apple fruit
Meltwater flow through a rapidly deglaciating glacier and foreland catchment system: Virkisjökull, SE Iceland
Virkisjökull is a rapidly retreating glacier in south-east Iceland. A proglacial lake has formed in the last ten years underlain by buried ice. In this study we estimate water velocities through the glacier, proglacial foreland and proglacial river using tracer tests and continuous meltwater flow measurements. Tracer testing from a glacial moulin to the glacier outlet in September 2013 demonstrated a rapid velocity of 0.58 m s�1. This was comparable to the velocity within the proglacial river, also estimated from tracer testing. A subsequent tracer test from the same glacial moulin under low flow conditions in May 2014 demonstrated a slower velocity of 0.07 m s�1. The glacier outlet river sinks back into the buried ice, and a tracer test from this sink point through the proglacial foreland to the meltwater river beyond the lake indicated a velocity of 0.03 m s�1,suggesting that an ice conduit system within the buried ice is transferring water rapidly beneath the
lake. Ground penetrating radar profiles confirm the presence of this buried conduit system. This study provides an example of rapid deglaciation being associated with extensive conduit systems that enable rapid meltwater transfer from glaciers through the proglacial area to meltwater rivers
E-Learning: Case Studies in Web-Controlled Devices and Remote Manipulation
Chances are that distance learning will transparently extend colleges and institutes of education and could plausibly overtake and turn into a preferred choice of higher education, especially for adult and working students. The main idea in e-learning is to build adequate solutions that can assure educational training over the Internet, without requiring a personal presence at the degree offering institution. The advantages are immediate and of unique importance, to enumerate a few: Education costs can be reduced dramatically, both from a student's perspective and the institution's (no need for room and board, for example); The tedious immigration and naturalization issues common with international students are eliminated; The limited campus facilities, faculty members and course schedules an institution can offer are no longer a boundary; Working adults can consider upgrading skills without changing their lifestyles We are presenting through this material a sequence of projects developed at University of Bridgeport and than can serve well in distance learning education ranging from simple "hobby" style training to professional guidance material. The projects have an engineering / laboratory flavor and are being presented in an arbitrary order, topics ranging from vision and sensing to engineering design, scheduling, remote control and operation
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