362 research outputs found
Unifying notions of pasting diagrams
In this work, we relate the three main formalisms for the notion of pasting diagram in strict ω-categories: Street's parity complexes, Johnson's pasting schemes and Steiner's augmented directed complexes. We first show that parity complexes and pasting schemes do not induce free ω-categories in general, contrarily to the claims made in their respective papers, by providing a counterexample. Then, we introduce a new formalism that is a strict generalization of augmented directed complexes, and corrected versions of parity complexes and pasting schemes, which moreover satisfies the aforementioned freeness property. Finally, we show that there are no other embeddings between these four formalisms
Exact synthesis of single-qubit unitaries over Clifford-cyclotomic gate sets
We generalize an efficient exact synthesis algorithm for single-qubit
unitaries over the Clifford+T gate set which was presented by Kliuchnikov,
Maslov and Mosca. Their algorithm takes as input an exactly synthesizable
single-qubit unitary--one which can be expressed without error as a product of
Clifford and T gates--and outputs a sequence of gates which implements it. The
algorithm is optimal in the sense that the length of the sequence, measured by
the number of T gates, is smallest possible. In this paper, for each positive
even integer we consider the "Clifford-cyclotomic" gate set consisting of
the Clifford group plus a z-rotation by . We present an
efficient exact synthesis algorithm which outputs a decomposition using the
minimum number of z-rotations. For the Clifford+T case
the group of exactly synthesizable unitaries was shown to be equal to the group
of unitaries with entries over the ring .
We prove that this characterization holds for a handful of other small values
of but the fraction of positive even integers for which it fails to hold is
100%.Comment: v2: published versio
Coherence of Gray Categories via Rewriting
Over the recent years, the theory of rewriting has been extended in order to provide systematic techniques to show coherence results for strict higher categories. Here, we investigate a further generalization to low-dimensional weak categories, and consider in details the first non-trivial case: presentations of tricategories. By a general result, those are equivalent to the stricter Gray categories, for which we introduce a notion of rewriting system, as well as associated tools: critical pairs, termination orders, etc. We show that a finite rewriting system admits a finite number of critical pairs and, as a variant of Newman\u27s lemma in our context, that a convergent rewriting system is coherent, meaning that two parallel 3-cells are necessarily equal. This is illustrated on rewriting systems corresponding to various well-known structures in the context of Gray categories (monoids, adjunctions, Frobenius monoids). Finally, we discuss generalizations in arbitrary dimension
Développement d’une méthode SPRi-MALDI-IMS pour la quantification et l’identification des protéines dans des empreintes de tissus biologiques
Plusieurs tests médicaux, comme celui du dépistage du cancer du sein, se basent sur l’observation de section tissulaire sous un microscope. Ces tests se basent sur l’interprétation d’un spécialiste et les résultats peuvent varier d’un expert à un autre dû la subjectivité des observations. L’utilisation d’une technique analytique offrant une quantification et une identification de cibles moléculaires dans une section tissulaire permettrait aux experts de produire des diagnostics plus objectifs et diminuerait possiblement le nombre de faux diagnostics.
Les travaux présentés dans ce mémoire portent sur le développement d’une technique SPRi-MALDI-IMS permettant l’imagerie en deux dimensions de protéines contenues dans une section tissulaire. La MALDI-IMS est la technique de choix pour l’imagerie de biomolécules dans les sections tissulaires. Par contre, elle ne parvient pas à elle seule à quantifier de façon absolue le matériel adsorbé à la surface. Donc, le couplage de la MALDI-IMS avec la SPRi permet la quantification absolue de protéines en deux dimensions et crée une technique répondant aux besoins des experts médicaux. Pour ce faire, nous avons étudié, l’effet de la chimie de surface sur la nature et la quantité de matériel adsorbé à la surface du capteur. De plus, la cinétique de transfert des protéines du tissu vers le capteur a dû être optimisée afin de produire des empreintes correspondant au tissu d’origine, afin d’atteindre la gamme dynamique des instruments SPRi et MALDI-IMS. La technique résultante de ces optimisations permet d’obtenir les premières images quantitatives et qualitatives de protéines en deux dimensions d’une seule section tissulaire.Several medical tests, such as breast cancer screening, are based on the observation of tissue section under a microscope. These tests rely on the interpretation of a specialist and the results can vary due to subjectivity of these analyses. Using an analytical technique able to quantify and identify molecular targets in a tissue section would enable experts to produce more objective diagnostic and possibly reduce the number of misdiagnosis.
The work presented in this thesis focuses on the development of a SPRi-MALDI-IMS technique for imaging proteins in a tissue section. MALDI-IMS is the contemporary technique of choice for biomolecule imaging in tissue sections. However, absolute quantification of material absorbed to the surface cannot be performed using MALDI-IMS. The absolute quantification of proteins in two dimensions was successfully achieved by coupling of the MALDI-IMS with SPRi. Accordingly, we investigated by studying the nature of the surface chemistry and the amount of material adsorbed on the sensor’s surface. In addition, the kinetics of the protein transfer had to be optimized to produce imprints corresponding to the transferred tissue and to reach the dynamic ranges of both SPRi and MALDI-IMS instruments. The resulting technique led to quantitative and qualitative images of proteins in two dimensions of a single tissue section. It is envisioned that SPRi-MALDI-IMS can eventually meet the needs of medical experts for pathological screening
Higher-order calculations of electron-deuteron scattering in nuclear effective theory
Motivated by recent advances in the application of effective field theory
techniques to light nuclei we revisit the problem of electron-deuteron
scattering in these approaches. By sidestepping problems with the description
of electron-nucleon scattering data in effective field theories, we show that
the effective theory expansion for deuteron physics converges well over a wide
range of momentum transfers. The resultant description of the physics of the
two-nucleon system is good up to virtual photon momenta of order 700 MeV.Comment: 18 pages, 7 figure
Neutron charge form factor at large
The neutron charge form factor is determined from an analysis of
the deuteron quadrupole form factor data. Recent calculations, based
on a variety of different model interactions and currents, indicate that the
contributions associated with the uncertain two-body operators of shorter range
are relatively small for , even at large momentum transfer . Hence,
can be extracted from at large without undue
systematic uncertainties from theory.Comment: 8 pages, 3 figure
Electron-deuteron scattering in a current-conserving description of relativistic bound states: formalism and impulse approximation calculations
The electromagnetic interactions of a relativistic two-body bound state are
formulated in three dimensions using an equal-time (ET) formalism. This
involves a systematic reduction of four-dimensional dynamics to a
three-dimensional form by integrating out the time components of relative
momenta. A conserved electromagnetic current is developed for the ET formalism.
It is shown that consistent truncations of the electromagnetic current and the
interaction kernel may be made, order-by-order in the coupling constants,
such that appropriate Ward-Takahashi identities are satisfied. A meson-exchange
model of the interaction is used to calculate deuteron vertex functions.
Calculations of electromagnetic form factors for elastic scattering of
electrons by deuterium are performed using an impulse-approximation current.
Negative-energy components of the deuteron's vertex function and retardation
effects in the meson-exchange interaction are found to have only minor effects
on the deuteron form factors.Comment: 42 pages, RevTe
Meson exchange currents in electromagnetic one-nucleon emission
The role of meson exchange currents (MEC) in electron- and photon-induced
one-nucleon emission processes is studied in a nonrelativistic model including
correlations and final state interactions. The nuclear current is the sum of a
one-body and of a two-body part. The two-body current includes pion seagull,
pion-in-flight and the isobar current contributions. Numerical results are
presented for the exclusive 16O(e,e'p)15N and 16O(\gamma,p)15N reactions. MEC
effects are in general rather small in (e,e'p), while in (\gamma,p) they are
always large and important to obtain a consistent description of (e,e'p) and
(\gamma,p) data, with the same spectroscopic factors. The calculated (\gamma,p)
cross sections are sensitive to short-range correlations at high values of the
recoil momentum, where MEC effects are larger and overwhelm the contribution of
correlations.Comment: 9 pages, 6 figure
Femtometer Toroidal Structures in Nuclei
The two-nucleon density distributions in states with isospin , spin
=1 and projection =0 and 1 are studied in H, He,
Li and O. The equidensity surfaces for =0 distributions are
found to be toroidal in shape, while those of =1 have dumbbell shapes
at large density. The dumbbell shapes are generated by rotating tori. The
toroidal shapes indicate that the tensor correlations have near maximal
strength at fm in all these nuclei. They provide new insights and simple
explanations of the structure and electromagnetic form factors of the deuteron,
the quasi-deuteron model, and the , and =2 (-wave)
components in He, He and Li. The toroidal distribution has a
maximum-density diameter of 1 fm and a half-maximum density thickness of
0.9 fm. Many realistic models of nuclear forces predict these values,
which are supported by the observed electromagnetic form factors of the
deuteron, and also predicted by classical Skyrme effective Lagrangians, related
to QCD in the limit of infinite colors. Due to the rather small size of this
structure, it could have a revealing relation to certain aspects of QCD.Comment: 35 pages in REVTeX, 25 PostScript figure
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