NEETs civic and political participation in outermost islands: The mediating roles of sense of community and agency

Our aim is to test the associations between collectivism, social support, sense of community, as well as agency with civic and political participation levels of NEETs living in The Azores, a group of islands forming a small and outermost archipelago. We surveyed 332 participants (M = 26.78; 69.30% women). We found that all factors, except for social support, were associated with higher participation levels among NEETs. We also found that stronger sense of community and agency mediated the connection between stronger collectivism and higher levels of participation. Therefore, we conclude that setting emotional bonds with the community and being involved in local traditions and causes are necessary conditions to translate dominant local values into NEETs civic and political participation in outermost islands. We further discuss how these results can be translated into more effective, person-centred policies to support NEETs inclusion

Structural and Functional Evolution of Glucose Transporter 4 (GLUT4): A Look at GLUT4 in Fish

The insulin-responsive glucose transporter GLUT4 was first described in 1988 as a result of studies on the regulation of glucose metabolism by insulin [1]. Soon after the discovery of GLUT4, several groups cloned GLUT4 in the human [2], rat [3,4] and mouse [5]. Since its discovery, GLUT4 has received, together with GLUT1, more experimental attention than any other single membrane transport protein. Structurally, GLUT4 follows the predicted model for class I glucose transporters. GLUT4 has a high affinity for glucose, with a Km of approximately 5 mM [6], and also transports mannose, galactose, dehydroascorbic acid and glucosamine [7-10]. In mammals, GLUT4 is mainly expressed in cardiac and skeletal muscle, brown and white adipose tissue, and brain [6,11,12]. GLUT4 plays a pivotal role in whole body glucose homeostasis, mediating the uptake of glucose regulated by insulin [13,14]. GLUT4 is responsible for the reduction in the postprandial rise in plasma glucose levels [6]. Insulin acts by stimulating the translocation of specific GLUT4-containing vesicles from intracellular stores to the plasma membrane (PM) resulting in an immediate increase in glucose transport [6,15]. The disruption of GLUT4 expression has been extensively associated with pathologies of impaired glucose uptake and insulin resistance such as type 2 diabetes and obesity [13,16-18]..

Influence of temperature, strain-rate and aging on the mechanical behaviour of an Al-Mg-Si alloy

Ce travail vise à analyser l'influence de la température, de la vitesse de déformation et de la durée de vieillissement sur le comportement mécanique de l'alliage EN AW 6016-T4, vieilli naturellement. Cet alliage a été sélectionné car il est couramment utilisé dans l'industrie automobile. Les essais mécaniques de traction ont été réalisés pour une gamme de température comprise entre la température ambiante et 300°C, pour différentes vitesses de déformation et à des temps différents après leur production. Les résultats constituent une nouvelle base de données expérimentale qui permettra d'évaluer les applications potentielles de la mise en forme à chaud de cet alliage

Application of microbial fuel cell technology for vinasse treatment and bioelectricity generation

Our study evaluated the performance of different two-chambered microbial fuel cell (MFC) prototypes, operated with variable distance between electrodes and Nafion membrane and specific inoculum concentration, applied for vinasse treatment.Instituto de Pesquisa Tecnológica do Estado de São Paulo/Programa Novos Talentos, through individual Research Grant attributed to Cristiane Angélica Ottoni.info:eu-repo/semantics/publishedVersio

Giant atypical lipoma

Liposarcomas correspond to the most common histological subtype of soft tissue sarcomas. They can be subdivided into: well differentiated or atypical lipoma, undifferentiated, myxoid, round, and pleomorphic cells. Atypical lipomas are the most prevalent and usually appear as asymptomatic softened tumors. They are locally aggressive but rarely lead to distant metastases. The diagnosis of this tumor is based on the imaging and histopathologic findings. Treatment consists of excision surgery with complete tumor removal. It has a good prognosis due to the low percentage of distant metastases. We report a rare case of giant atypical lipoma as well as the adopted therapy and evolution.Univ Fed Sao Paulo UNIFESP, Dept Dermatol, Sao Paulo, SP, BrazilUniv Fed Sao Paulo UNIFESP, Dept Pathol, Sao Paulo, SP, BrazilUniv Fed Sao Paulo UNIFESP, Dept Dermatol, Sao Paulo, SP, BrazilUniv Fed Sao Paulo UNIFESP, Dept Pathol, Sao Paulo, SP, BrazilWeb of Scienc

Biotratamento de vinhaça sintética e geração de eletricidade utilizando uma célula a combustível microbiana

Avanços Científicos e Tecnológicos em BioprocessosO Brasil é um dos maiores produtores de etanol no mundo, no entanto, durante o processo de obtenção deste combustível, elevadas quantidades de vinhaça são geradas, em média, para cada litro de etanol produzido são gerados 13 litros deste resíduo. A vinhaça possui propriedades físicas e químicas que podem desencadear efeitos nocivos à biota, deste modo, existe um interesse crescente em identificar novas tecnologias para o seu tratamento. A utilização de células a combustível microbianas (CCMs) apresenta um enorme potencial, uma vez que, pode promover simultaneamente o tratamento deste resíduo e a biogeração de energia elétrica, pela conversão da energia química disponível nesses substratos biodegradáveis diretamente em eletricidade, por meio da ação catalítica de bactérias eletrogênicas aderidas ao eletrodo. Neste contexto, o presente estudo avaliou a utilização de uma CCM de câmara dupla no tratamento de vinhaça sintética. Durante a operação deste reator foi detectada uma máxima densidade de potência de 330 mW·m-2 e uma redução na demanda química de oxigênio (DQO) em 58,8% após 28 dias. Diante destes resultados preliminares, a tecnologia CCM pode ser considerada promissora no tratamento da vinhaça, contudo, estudos a respeito da configuração, tipo de inóculo e formas de operação da CCM são necessários para que amplie sua eficiência.Brazil is one of the largest producers of ethanol in the world, however, during the process of obtaining ethanol, high quantities of vinasse are generated, on average, for each liter of ethanol produced, 13 liters of this residue is generated. Vinasse has physical and chemical properties that can trigger harmful effects on biota, so there is a growing interest in identifying new technologies for its treatment. The use of microbial fuel cells (CCMs) presents a very high potential, since it can simultaneously promote the treatment of this residue and the biogeneration of electric energy, by converting the available chemical energy in these biodegradable substrates and directly into electricity, by means of the action of electrogenic bacteria adhered to the electrode. In this context, the present study evaluated the use of a double chamber CCM in the treatment of synthetic vinasse. During the operation of this reactor, a maximum power density of 330 mW m-2 and a reduction in chemical oxygen demand (COD) was detected at 58.8% after 28 days. Considering these preliminary results, CCM technology may be considered promising in the treatment of vinasse, however, studies regarding the configuration, type of inoculum and forms of CCM operation are necessary to increase its efficiency.info:eu-repo/semantics/publishedVersio

SILENCIO: Introduction of electric propulsion to small inshore fishing boats to reduce their impact in the environment

Human activities afects each environment, even the most remote, and the acoustic impact that these activities generate on the marine environment is not an exception. The Silencio project aims to developed innovative and sustainable solutions to reduce the impact of fsheries and shell-fsheries in ecosystems, mainly noise but also carbon footprint, by the assessment of the use of electric propulsion by small inshore fshing boat. Besides, the knowledge about the sources of underwater noise in areas under high fshing pressure will be improved by the characterization of the ambient noise in Rías Baixas. Further, the project will spread the idea of an environmentally sustainable, socially responsible and economically viable extractive sector.Peer Reviewe

Neuroretinitis caused by Bartonella henselae: case report

Bolest mačjeg ogreba je zarazna bolest uzrokovana bakterijom Bartonella henselae, a obilježena je regionalnom limfadenopatijom i vrućicom. Iako i drugi organi mogu biti zahvaćeni, oči su rijetko zahvaćene (5% - 10%), što se može manifestirati kao neuroretinitis. Prikazujemo slučaj 11-godišnjeg dječaka primljenog na hitni odjel zbog gubitka vida na desnom oku, što je otkriveno probirnim testiranjem vida. Oftalmološki pregled pokazao je otok diska, peripapilarna mikrokrvarenja i edem makule s eksudatima bogatim lipidima, što je ukazivalo na zvjezdastu makulu. Serološki testovi pokazali su povišeni titar protutijela na Bartonella henselae. Bolesnik je liječen rifampicinom i doksiciklinom, uz optimalan terapijski odgovor. Neuroretinitis je rijetka manifestacija infekcije bakterijom Bartonella henselae i na njega treba posumnjati u svakog bolesnika u kojega se uz gubitak vidne oštrine utvrdi oticanje diska, zvjezdasti eksudati makule te kontakt s mačkama u anamnezi. Kod većine bolesnika predinfekcijska vidna funkcija oporavi se u većoj mjeri ili potpuno, međutim, u manjeg broja bolesnika s naročito teškim neuroretinitisom mogu ostati posljedice u funkciji vida. Nema randomiziranih istraživanja učinkovitosti liječenja, no čini se da antibiotska terapija rifampicinom i doksiciklinom skraćuje tijek bolesti i ubrzava oporavak vida.Cat scratch disease is an infectious disease caused by Bartonella henselae characterized by regional lymphadenopathy and fever. Although it may involve other organs, ocular involvement is rare (5%-10%) and may manifest as neuroretinitis. We present a case of an 11-year-old patient admitted to the emergency department because of vision loss on the right eye, detected on a vision screening test. Ophthalmological evaluation showed disc swelling, peripapillary microhaemorrhages and macular oedema with lipid-rich exudates, suggestive of the macular star pattern. Serological studies revealed elevated titre of antibodies to Bartonella henselae. The patient was treated with rifampicin and doxycycline, with optimal response. Neuroretinitis is an uncommon manifestation of Bartonella henselae infection and should be suspected in any patient presenting loss of visual acuity, along with the fi nding of disc swelling, macular star exudates, and a history of contact with cats. Most patients recover most or all of their pre-infection visual function, however, a small subset of patients with particularly severe neuroretinitis may be left with optic sequelae. There are no randomized trials on the eff ectiveness of treatment but antibiotic therapy with rifampicin and doxycycline seems to shorten the course of the disease and hasten visual recovery