Vichy goes to Brazil: the road to success

The objective of this case was to study how the cultural variables can influence the internationalization process of a brand, and how the marketing strategy can be designed balancing standardization and adaptation in order to not only achieve scale gains, but also guarantee a certain level of appropriateness to the characteristics of the consumer market being considered. The case was organized as follows: first the history of the Vichy brand is contextualized; then, its expansion process for the Brazilian market is approached; and, finally, the future challenges for Vichy in Brazil are discussed.info:eu-repo/semantics/acceptedVersio

Laser Induced Breakdown Spectroscopy

This review describes the fundamentals, instrumentation, applications and future trends of an analytical technique that is in its early stages of consolidation and is establishing its definitive niches among modern spectrometric techniques. The technique has been named Laser Induced Breakdown Spectroscopy (LIBS) and its main characteristic stands in the use of short laser pulses as the energy source to vaporize samples and excite the emission of electromagnetic radiation from its elements and/or molecular fragments. The emitted radiation is analyzed by high resolution optics and the intensities are recorded, usually by fast triggered solid state detectors. Together, these devices allow producing and registering a wide ranging emission spectrum of the short-lived phenomenon induced by the laser pulse. The spectrum contains qualitative and quantitative information which can be correlated with sample identity or can be used to determine the amount of its constituents. This review is divided in four parts. First, the relevant historical and theoretical concepts associated with LIBS are presented; then the main practical aspects of the several experimental and instrumental approaches employed for implementation of the technique are critically described; the applications related in the literature, including those making use of chemometrics, are classified and exemplified with relevant and recently published work. Finally, an attempt to portray an overall evaluation and future perspectives of the technique are presented.Esta revisão descreve os aspectos fundamentais, a instrumentação, as aplicações e tendências futuras de uma técnica analítica que se encontra em seu estágio de consolidação e que está em vias de estabelecer o seu nicho entre as técnicas espectrofotométricas modernas. A técnica é denominada Espectroscopia de Emissão em Plasma Induzido por Laser (em inglês, Laser Induced Breakdown Spectroscopy, LIBS) e sua principal característica está no uso de pulsos de laser como fonte de energia para vaporizar a amostra e excitar a emissão de radiação eletromagnética, a partir de seus elementos e/ou fragmentos moleculares. A radiação emitida é analisada por meio de instrumentos ópticos de alta resolução e as suas intensidades são medidas, usualmente com detectores rápidos de estado sólido. Em conjunto, esses dispositivos permitem a geração e a medida de um espectro de emissão de faixa ampla do fenômeno induzido pelo pulso de laser. O espectro registrado contém informação qualitativa e quantitativa que pode ser correlacionada com a identidade da amostra ou empregada na determinação da quantidade de seus constituintes. Essa revisão é dividida em quatro partes. A primeira aborda aspectos históricos da técnica e os conceitos teóricos relevantes associados com LIBS; então, os aspectos práticos de diversas abordagens experimentais e instrumentais empregadas na implementação da técnica são revistos de forma crítica; as aplicações encontradas na literatura, incluindo aquelas que empregam quimiometria, são classificadas e exemplificadas por meio de trabalhos relevantes recentemente publicados. Finalmente, uma tentativa de estabelecer uma avaliação global e as perspectivas futuras para a técnica é apresentada.463512Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Inequalities for eigenvalues of operators in divergence form on Riemannian manifolds isometrically immersed in Euclidean space

In this paper, we compute universal inequalities of eigenvalues of a large class of second-order elliptic differential operators in divergence form, that includes, e.g., the Laplace and Cheng-Yau operators, on a bounded domain in a complete Riemannian manifolds isometrically immersed in Euclidean space. A key step in order to obtain the sequence of our estimates is to get the right Yang-type first inequality. We also prove some inequalities for manifolds supporting some special functions and tensors.Comment: 15 pages. arXiv admin note: text overlap with arXiv:2206.0943

Growing healthy is fun! A co-creation nutrition intervention to children aged 3-6 years

In order to promote healthier eating habits and consequently lower obesity levels, that it is important for children to have knowledge of diet and nutrition. Objectives: Increase nutritional knowledge about healthy eating and Portuguese food wheel in children aged 3-6years. Methods: Our group developed the Growing Healthy is Fun! to 3-6 years old children, at the Kindergarten of Obra Kolping. Several funny activities were planned, in order to instill knowledge about healthy eating and Portuguese food wheel, leading to best eating practices and adequate nutritional status. Structured interviews were conducted with the children pre and post the intervention for all children that parents or guardian delivered a written informed consent. Results: At pre intervention, the percentages of children that considered the example food as healthy food are: 100% for apple, beans, carrots and unflavored milk; 57.1% for fish; 28.6% for chocolate and cake. At post intervention the results are: 100% for apple, beans, carrots and unflavored milk; 85,7% for fish; and 0% for chocolate, cake and pizza. About Portuguese food wheel knowledge, at pre intervention, all children indicated cauliflower and banana, 71.4% considered olive oil and plain milk, 42.9% considered cake, and 28.7% considered egg and candy as foods belonging to the wheel. In post intervention, 100% of children considered egg, olive oil, cauliflower and bananas as food belonging to the wheel and 71.4% of them considered milk as belonging to the food wheel. Chocolate, candies, hamburger and cake were not classified as part of the food wheel.info:eu-repo/semantics/publishedVersio

Companion animals-An overlooked and misdiagnosed reservoir of carbapenem resistance

Research Areas: Infectious Diseases ; Pharmacology & PharmacyABSTRACT - The dissemination of antimicrobial-resistance is a major global threat affecting both human and animal health. Carbapenems are human use β-lactams of last resort; thus. the dissemination of carbapenemase-producing (CP) bacteria creates severe limitations for the treatment of multidrugresistant bacteria in hospitalized patients. Even though carbapenems are not routinely used in veterinary medicine, reports of infection or colonization by carbapenemase-producing Enterobacterales in companion animals are being reported. NDM-5 and OXA-48-like carbapenemases are among the most frequently reported in companion animals. Like in humans, Escherichia coli and Klebsiella pneumoniae are the most represented CP Enterobacterales found in companion animals, alongside with Acinetobacter baumannii. Considering that the detection of carbapenemase-producing Enterobacterales presents several difficulties, misdiagnosis of CP bacteria in companion animals may lead to important animal and public-health consequences. It is of the upmost importance to ensure an adequate monitoring and detection of CP bacteria in veterinary microbiology in order to safeguard animal health and minimise its dissemination to humans and the environment. This review encompasses an overview of the carbapenemase detection methods currently available, aiming to guide veterinary microbiologists on the best practices to improve its detection for clinical or research purposes.info:eu-repo/semantics/publishedVersio

Productivity of three sugarcane cultivars under dry and drip irrigated management

O objetivo neste trabalho foi estudar o efeito da tecnologia de irrigação por gotejamento, em cultivares de cana-de-açúcar, em dois ciclos de produção (cana-planta e cana-soca). O delineamento experimental utilizado foi o de blocos ao acaso, com quatro repetições, constituídos pela combinação de três cultivares de cana-de-açúcar: RB867515; RB855536 e SP80-3280, e dois manejos da cultura: sistema de irrigação por gotejamento subterrâneo e sistema de sequeiro, totalizando seis tratamentos. O primeiro ciclo teve duração de 336 dias, ocorrendo precipitação de 1.480 mm. O volume de água disponibilizado pelo sistema de irrigação por gotejamento foi de 400 mm, totalizando 1.880 mm. O segundo ciclo teve duração de 365 dias, cujo volume de água por meio de precipitação foi de 1.394 mm; somados aos 320 mm fornecidos pelo sistema de irrigação, totalizaram 1.714 mm. Ocorreu interação entre manejo e cultivar para as variáveis: produtividade de colmos (TCH) e produtividade de açúcar (TPH) em que a maior diferença foi observada para a cultivar SP80-3280. As cultivares apresentaram respostas diferenciadas na eficiência de utilização da água. No manejo irrigado por gotejamento houve elevação de 24% na produtividade de colmos e de 23% na produtividade de açúcar, em relação ao manejo de sequeiro.This study aimed to evaluate the effect of drip irrigation technology in different sugarcane varieties in two crop cycles (plant cane and ratoon). The experimental design was in completly randomized blocks, in split-plot with four replications, constituted by three sugarcane genotypes: RB867515; RB855536 and SP80-3280 and two crop management: drip irrigation system and rainfed system, totalizing six treatments. The first cycle lasted for 336 days, with rainfall of 1,480 mm. The volume of water provided by the system of drip irrigation was 400 mm, totaling 1,880 mm. The second cycle lasted for 365 days, the volume of water through rainfall was 1,394 mm, added to 320 mm provided by the system of irrigation, totaled 1,714 mm. Interaction between management and cultivars was found significant for the variables: productivity of stalks (TCH) and sugar yield (TPH), in which the largest difference was observed for cultivar SP80-3280. There was significant response to drip irrigation, on average the increase of production of stalks and sugar was 24 and 23%, respectively

Sex Differences in Desiccation Tolerance Varies by Colony in the Mesic Liverwort \u3ci\u3ePlagiochila porelloides\u3c/i\u3e

Water scarcity, a common stress factor, negatively impacts plant performance. Strategies to cope with it, such as desiccation tolerance, are becoming increasingly important to investigate. However, phenomena, such as intraspecific variation in stress responses have not received much attention. Knowledge of this variability and the environmental drivers can be leveraged to further investigate the mechanisms of desiccation tolerance. Here we tested for variation in desiccation tolerance in Plagiochila porelloides among colonies and sexes within the same riparian zone. Field-collected dehardened plants were subjected to a desiccation event, under controlled conditions and then rehydrated. Plant water status, photosynthetic rates, net carbon gain, and efficiency of photosystem II (PSII) were assayed to evaluate tissue desiccation, basic metabolic processes and plant recovery. To establish a linkage between plant response and environmental factors, field light conditions were measured. We detected intraspecific variation, where a more exposed colony (high percentage of open sky, large temporal range of light quantity, and high red/far-red ratio) showed sex differences in desiccation tolerance and recovery. Overall, PSII recovery occurred by 72 h after rehydration, with a positive carbon gain occurring by day 30. This within species variation suggests plastic or genetic effects, and likely association with light conditions

GAMBARAN PERAN PENGAWAS MENELAN OBAT (PMO) PADA KELUARGA DENGAN TBC PARU DI WILAYAH KERJA PUSKESMAS KOTA ATAMBUA DAN PUSKESMAS HALIWEN

Pendahuluan: Tuberculosis disebabkan oleh kuman mycobakterium tuberculosis. Pengobatan TB paru memerlukan waktu yang cukup panjang yaitu selama 6 bulan, sehingga salah satu faktor yang dapat mempengaruhi keberhasilan pengobatan tuberculosis adalah peran pengawas menelan obat (PMO). Tujuan: penelitian ini bertujuan untuk mengetahui gambaran peran pengawas menelan obat (PMO) pada anggota keluarga dengan TBC paru di Wilayah kerja Puskesmas Kota Atambua dan Puskesma Haliwen. Metode penelitian: Penelitian ini adalah penelitian deskriptif yang dilakukan di Puskesmas Kota Atambua dan Puskesmas Haliwen pada tanggal 11 November – 25 November 2022. Sampel diambil menggunakan total sampling dengan total responden sebanyak 30 PMO yang tersebar di Wilayah kerja Puskesmas Kota Atambua dan Puskesmas Haliwen. Hasil: Hasil penelitian menunjukan bahwa 83.3% PMO berhasil menjalankan peran sebagai PMO, 16% tidak berhasil menjalankan peran sebagai PMO. Kesimpulan: Hasil penelitian menunjukan bahwa sebagian besar subjek penelitian berhasil melakukan peran sebagai PMO

Endothelial Wall Thickness, Cardiorespiratory Fitness And Inflammatory Markers In Obese And Non-obese Adolescents.

Increased carotid intima-media thickness (c-IMT) is considered a marker of early-onset atherosclerosis and it has been found in obese children and adolescents, but the risk factors associated with this population remain to be elucidated. To compare and verify the relationship between c-IMT, metabolic profile, inflammatory markers, and cardiorespiratory fitness in obese and non-obese children and adolescents. Thirty-five obese subjects (19 boys) and 18 non-obese subjects (9 boys), aged 10-16 years, were included. Anthropometry, body composition, blood pressure, maximal oxygen consumption (VO2max), and basal metabolic rate were evaluated. Serum glucose, insulin, homeostasis model assessment of insulin resistance (HOMA-IR), blood lipids, C-reactive protein (CRP), and adiponectin were assessed. c-IMT was measured by ultrasound. The results showed that c-IMT, triglycerides, insulin, HOMA-IR, and CRP values were significantly higher in the obese group than in the non-obese group, and high-density lipoprotein cholesterol (HDL-c), adiponectin, and VO2max values were significantly lower in the obese group than in the non-obese group. The c-IMT was directly correlated with body weight, waist circumference, % body fat, and HOMA-IR and inversely correlated with % free fat mass, HDL-c, and VO2max. Our findings show that c-IMT correlates not only with body composition, lipids, insulin resistance, and inflammation but also with low VO2max values in children and adolescents.1847-5