Luziânia, Plano Diretor e inserção metropolitana

Dissertação (mestrado)—Universidade de Brasília, Faculdade de Arquitetura e Urbanismo, Programa de Pós-Graduação em Arquitetura e Urbanismo, 2019.O fenômeno da urbanização sem planejamento trouxe consequências sérias para o Brasil, como problemas de infraestrutura e mobilidade urbana e afetou cidades metropolitanas, como Brasília. O município de Luziânia, integrante da Área Metropolitana de Brasília, é uma das cidades que sofre com as mazelas causadas pela metropolização descontrolada, dependendo de serviços e empregos oferecidos pelo Plano Piloto de Brasília. O Plano Diretor de Luziânia de 2006, embora busque trazer alternativas para estimular a autonomia da cidade, propondo uso misto para quase todo o território, pouco colabora para promover uma dinâmica econômica que gere tal independência, já que a pesquisa evidenciou que o crescimento de Luziânia se deu majoritariamente pelo uso residencial unifamiliar, que reforça o estereótipo de cidades-dormitório da coroa metropolitana de Brasília.The phenomenon ofunplanned urbanization has had serious consequences for Brazil, such as infrastructure problems and urban mobility, and affected metropolitan cities such as Brasília. The municipality of Luziania, part ofthe Metropolitan Area of Brasília, is one of the cities that suffers from the ills caused by uncontrolled metropolization, depending on Services and jobs offered by the Plan Pilot of Brasília. The 2006 Master Plan of Luziania, although seeking to bring alternatives to stimulate the autonomy of the City, proposing mixed use for almost the whole territory, does little to promote an economic dynamic that generates such independence, since the research evidenced that the growth of Luziania was given mainly by single-family residential use, which reinforces the stereotype of dormitory cities ofthe metropolitan crown of Brasília

Reforzando el vínculo paternal: relato de un evento de incentivo a la participación activa de la figura paterna en la inmunización infantil

A imunização é uma das principais estratégias para garantir a proteção de seres humanos contra determinadas doenças infectocontagiosas. Sabe-se que a indução artificial de imunidade humana contra enfermidades ocorre desde os primeiros dias de vida, exigindo, portanto, a participação efetiva dos pais de recém nascidos nesse processo de proteção. Nesse contexto, destaca-se, expressivamente, a atuação das figuras maternas, o que confere a necessidade de se promover ações educativas as quais induzem e instruem figuras paternas a terem maior contato com a vacinação de seus descendentes. O presente artigo tem o objetivo de relatar a vivência de estudantes de medicina ao promoverem um momento educativo para figuras paternas acerca de sua participação na vacinação de seus filhos. Trata-se de um relato de experiência, que expõe a percepção de estudantes de Medicina ao planejarem e executarem um evento educativo-extensionista. Tal acontecimento embasou-se na distribuição de panfletos e apresentação de banners, os quais continham informações acerca da necessidade da participação paterna na imunização infantil, bem como acerca do reaparecimento de doenças erradicadas. Após as atividades educativas, percebeu-se que a ação foi bem sucedida, que o público alvo aceitou e envolveu-se nessa proposta de comunicação em saúde e que as informações foram passadas de forma eficiente. Ainda, ficou claro que muitos personagens paternos convivem com muitas dúvidas acerca da importância da imunização e admitem não serem atuantes na imunização de seus filhos.Immunization is one of the main strategies to ensure the protection of human beings against certain infectious diseases. It is known that artificial induction of human immunity against diseases occurs from the first days of life, thus requiring the effective participation of parents of newborns in this process of protection. In this context, the role of maternal figures is significantly highlighted, which gives the need to promote educational actions that induce and instruct father figures to have greater contact with the vaccination of their descendants. This article aims to report the experience of medical students to promote an educational moment for father figures about their participation in the vaccination of their children. This is an experience report, which exposes the perception of medical students when planning and executing an educational-extensionist event. This event was based on the distribution of pamphlets and presentation of banners, which contained information about the need for paternal participation in childhood immunization, as well as about the reappearance of eradicated diseases. After the educational activities, it was noticed that the action was successful, that the target audience accepted and was involved in this health communication proposal and that the information was passed efficiently. Still, it was clear that many paternal characters live with many doubts about the importance of immunization and admit not being active in the immunization of their children.La inmunización es una de las principales estrategias para garantizar la protección de los seres humanos contra determinadas enfermedades infectocontagiosas. Se sabe que la inducción artificial de inmunidad humana contra enfermedades ocurre desde los primeros días de vida, exigiendo, por lo tanto, la participación efectiva de los padres de recién nacidos en este proceso de protección. En ese contexto, se destaca, expresivamente, la actuación de las figuras maternas, lo que confiere la necesidad de promover acciones educativas las cuales inducen e instruyen figuras paternas a tener mayor contacto con la vacunación de sus descendientes. El presente artículo tiene el objetivo de relatar la vivencia de estudiantes de medicina al promover un momento educativo para figuras paternas acerca de su participación en la vacunación de sus hijos. Se trata de un relato de experiencia, que expone la percepción de estudiantes de Medicina al planificar y ejecutar un evento educativo-extensionista. Este acontecimiento se basó en la distribución de folletos y la presentación de pancartas, que contenían información sobre la necesidad de la participación paterna en la inmunización infantil, así como sobre la reaparición de enfermedades erradicadas. Después de las actividades educativas, se percibió que la acción fue exitosa, que el público objetivo aceptó y se involucró en esa propuesta de comunicación en salud y que las informaciones fueron transmitidas de forma eficiente. Aún, quedó claro que muchos personajes paternos conviven con muchas dudas acerca de la importancia de la inmunización y admiten no ser actuantes en la inmunización de sus hijos

Estudo dos dados epidemiológicos dos casos de Covid-19 na região metropolitana do Cariri, Ceará, Brasil: Study of epidemiological data on Covid-19 cases in the metropolitan region of Cariri, Ceará, Brazil

O SARS-CoV-2 é altamente contagioso e é transmitido rapidamente por via respiratória. Os focos iniciais de transmissão da COVID-19 no Brasil ocorreram nos estados de São Paulo e do Rio de Janeiro, com disseminação célere para as restantes das capitais. Nos primeiros meses, o Ceará liderou posições no Nordeste e no Brasil em número de casos confirmados da doença. Esta não apresenta distribuição de forma homogênea nas regiões do país, especialmente em regiões interioranas. Dessa forma, este estudo tem como objetivo avaliar a dinâmica dos dados epidemiológicos dos casos de COVID-19 na Região Metropolitana do Cariri cearense. Efetuou-se uma pesquisa descritiva de natureza qualitativa e método dedutivo, a qual foi verificada a distribuição de casos na Região Metropolitana do Cariri (RMC) através de dados por meio do Boletim Epidemiológico Novo Coronavírus (COVID-19), disponível no site do IntegraSUS da Secretaria da Saúde do Ceará. Os resultados mostraram que, até o dia 30 de junho de 2022, contabilizam 245.382 casos notificados, sendo 94.408 confirmados da COVID-19, distribuídos em todos os 9 municípios da RMC. Desse total de casos confirmados, 89.400 casos são casos recuperados, equivalente a 94,69%. O número de óbitos notificados foi 1.500, sendo a taxa de letalidade em 1,6%. Atualmente, foram registrados 266.369 exames, sendo 36,2% testes rápidos para antígenos, seguidos de 35,4% de testes rápidos para pesquisa de anticorpos IGG, 24,3% RT-PCR e os demais números somam teste sorológico para pesquisa de anticorpos IgG e IgM, ECLIA, ELISA, RT-LAMP e Imunocromatografia. Em relação ao quadro sociodemográfico, há predominância da contaminação em mulheres, em indivíduos pardos e na faixa etária de 20 a 44 anos. Desse modo, embora o auge da pandemia causada pelo vírus SARS-CoV-2 já tenha sido superado em grande parte do mundo graças, principalmente, à vacinação em massa, a COVID-19 persiste como um problema de saúde pública que deve ser constantemente monitorado e estudado, com o fito de demonstrar caminhos para a criação de estratégias que visem o enfrentamento de epidemias

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Panoramic snapshot of serum soluble mediator interplay in pregnant women with convalescent COVID-19: an exploratory study

IntroductionSARS-CoV-2 infection during pregnancy can induce changes in the maternal immune response, with effects on pregnancy outcome and offspring. This is a cross-sectional observational study designed to characterize the immunological status of pregnant women with convalescent COVID-19 at distinct pregnancy trimesters. The study focused on providing a clear snapshot of the interplay among serum soluble mediators.MethodsA sample of 141 pregnant women from all prenatal periods (1st, 2nd and 3rd trimesters) comprised patients with convalescent SARS-CoV-2 infection at 3-20 weeks after symptoms onset (COVID, n=89) and a control group of pre-pandemic non-infected pregnant women (HC, n=52). Chemokine, pro-inflammatory/regulatory cytokine and growth factor levels were quantified by a high-throughput microbeads array.ResultsIn the HC group, most serum soluble mediators progressively decreased towards the 2nd and 3rd trimesters of pregnancy, while higher chemokine, cytokine and growth factor levels were observed in the COVID patient group. Serum soluble mediator signatures and heatmap analysis pointed out that the major increase observed in the COVID group related to pro-inflammatory cytokines (IL-6, TNF-α, IL-12, IFN-γ and IL-17). A larger set of biomarkers displayed an increased COVID/HC ratio towards the 2nd (3x increase) and the 3rd (3x to 15x increase) trimesters. Integrative network analysis demonstrated that HC pregnancy evolves with decreasing connectivity between pairs of serum soluble mediators towards the 3rd trimester. Although the COVID group exhibited a similar profile, the number of connections was remarkably lower throughout the pregnancy. Meanwhile, IL-1Ra, IL-10 and GM-CSF presented a preserved number of correlations (≥5 strong correlations in HC and COVID), IL-17, FGF-basic and VEGF lost connectivity throughout the pregnancy. IL-6 and CXCL8 were included in a set of acquired attributes, named COVID-selective (≥5 strong correlations in COVID and <5 in HC) observed at the 3rd pregnancy trimester.Discussion and conclusionFrom an overall perspective, a pronounced increase in serum levels of soluble mediators with decreased network interplay between them demonstrated an imbalanced immune response in convalescent COVID-19 infection during pregnancy that may contribute to the management of, or indeed recovery from, late complications in the post-symptomatic phase of the SARS-CoV-2 infection in pregnant women

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost