104 research outputs found

    Are rises in Electro-Magnetic Field in the human environment, interacting with multiple environmental pollutions, the tripping point for increases in neurological deaths in the Western World?

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    © 2019 Elsevier Ltd Whilst humans evolved in the earth's Electro-Magnetic-Field (EMF) and sun-light, both being essential to life but too much sun and we burn. What happens if background EMF rise to critical levels, coinciding with increasing environmental pollutants? Two of the authors can look back over 50 clinical years and appreciate the profound changes in human morbidity across a range of disparate conditions – autoimmune diseases, asthma, earlier cancer incidence and reduced male sperm counts. In particular have been increased autism, dyslexia, Attention Deficit Hyperactivity Disorder and neurological diseases, such as Amyotrophic Lateral Sclerosis, Multiple Sclerosis, Parkinson's Disease, Early Onset Dementia, Multiple System Atrophy and Progressive Supranuclear Palsy. What might have caused these changes-whilst genetic factors are taken as given, multiple environmental pollutants are associated with neurological disease although the mechanisms are unclear. The pace of increased neurological deaths far exceeds any Gompertzian explanation - that because people are living longer they are more likely to develop more age-related problems such as neurological disease. Using WHO global mortality categories of Neurological Disease Deaths (NDD) and Alzheimer's and Dementia deaths (Alz), updated June 2018, together they constitute Total Neurological Mortality (TNM), to calculate mortality rates per million for people aged 55–74 and for the over-75's in twenty-one Western countries. Recent increases in American people aged over-75's rose 49% from 1989 to 2015 but US neurological deaths increased five-fold. In 1989 based on Age-Standardised-Deaths-Rates America USA was 17th at 324 pm but rising to 539 pm became second highest. Different environmental/occupational factors have been found to be associated with neuro-degenerative diseases, including background EMF. We briefly explore how levels of EMF interact upon the human body, which can be described as a natural antennae and provide new evidence that builds upon earlier research to propose the following hypothesis. Based upon recent and new evidence we hypothesise that a major contribution for the relative sudden upsurge in neurological morbidity in the Western world (1989–2015), is because of increased background EMF that has become the tipping point-impacting upon any genetic predisposition, increasing multiple-interactive pollutants, such as rises in petro-chemicals, hormone disrupting chemicals, industrial, agricultural and domestic chemicals. The unprecedented neurological death rates, all within just twenty-five years, demand a re-examination of long-term EMF safety related to the increasing background EMF on human health. We do not wish to 'stop the modern world’, only make it safer

    Two-Year Cohort of 88 Multiple System Atrophy Patients’ Occupations and Incidence of Electric Shock and Head Injury: A Hypothesis Stimulating Pilot Study

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    Introduction: Multiple Systematic Atrophy (MSA) whose incidences have virtually doubled, in … years (how many) coinciding with confirmed major rises in total neurological mortality in the developed world. The aetiology of neurological diseases is linked to various `Possible Occupations Linked’ (POL) to neurological disease- Electronics and IT; Engineering, Chemicals, Solvents. Two inconsistent findings - electric shock and head injury have been reported by many MSA patients. This pilot study analyses differences between MSA patients and the general population in regard to occupation and incidence of electric shock and head injury. Methodology: A two-year cohort of MSA patients attending support groups completed a one page self-administered questionnaire. It explored age, sex, occupation and electric shock and head injury, contrasted with estimates in the General Public, occupations were determined from ONS data, from which odds ratios of patients and general population were calculated. Results: [Colin these figures are a bit puzzling but I am not a statistician] Of the 88 patients, 34% were aged <60; 56% occupations were POL compared to 24% in the regional population; one in 1.52 MSA patients reported head injury 1:1.52 and 1:3.26 electric shock. This yielded odd ratios of patients to general population of 1: 91.4 and 1: 589.9 respectively. Patents with Other occupations had significantly more trauma than POL patients. Discussion: Despite the limits of the study 34% of the cohort were relatively young for neurological disease, double the 'possible occupational links’ to neurological disease than the general population and substantially higher trauma incidence. This pilot study indicates the need for a more focused analysis of possible tripping [? or is contributory better] factors in the aetiology of MSA

    Acute Flaccid Myelitis-Possible Link with Electro-Magnetism? A Hypothesis Stimulating Study.

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    “Wonder grows when knowledge fails” (Francis Bacon 1561-1626) A new polio-like condition mainly affecting children (mean 5 years old) is being observed, starting with viral and respiratory symptoms, followed by a demyelination paralysis. Known as Acute Flaccid Myelitis, first identified in 2010 in America, 28% to 95% of cases are associated with Enterovirus EVD68. Yet EVD68 itself was identified decades previously in China and the Netherlands. Prior to hospitalisation some children had no evidence of neurological symptoms, hinting a possible environmental trigger. Acute hospitals have multiple sources of background Electro-Magnetic-Field (EMF), some above recommended safety levels. Hence the hypothesis “Are critical rises in human background electromagnetism, interacting with other environmental factors, possibly a casual factor, in Acute Flaccid Myelitis? “There is evidence that low frequency EFM creates cellular oxidative stress leading to neurodegeneration. Mechanisms are unclear but could ubiquitous background EMF play a role in children’s vulnerability to EVD68? The context of the hypothesis is the evidence of accelerating rates of neurological morbidity in the 21st Century and whether the range and multiplicity of environmental factors are impacting upon an immune-compromised child’s neurology. As health environmental factors were ignored in the past, e.g. smoking and asbestos, another possible environmental linked anomaly is feared, though we note the recent establishment of the UK Acute Flaccid Paralysis Task Force in 2019. This hypothesis, whilst remaining speculative, needs to be refuted through independent research to ensure that AFM is not another children’s neurological condition, which once were rare but now becoming more commonplace

    Neurological Deaths in the 21st Century in 21 Western Countries: Demographics or Environmental Causes

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    Introduction: There is evidence of rising neurological deaths in the Western world. This study examines any changes during the 21st century to indicate whether the causes are primarily demographic or environmental. Method: All data based upon WHO mortality rates per million (pm) for WHO mortality categories Nervous Disease Deaths (NDD) and Alzheimer and Other Dementias Deaths (AlzD) to calculate a Combined Neurological Mortality rate for people aged 55-74 Year Olds (lower than Western life-expectancy) and AGE-STANDARDISED-DEATH-RATES (ASDR) (pm) for both sexes. Over75’s neurological deaths and population numbers analyzed to determine if increased mortality mainly due to an ageing population. Results: 55-74Year Olds: NDD rates were higher than AlzD in every country. Combined rates rose substantially in ten countries, although Canadian and French rates fell. Total ASDR: NDD and AlzD increased substantially in all countries. Highest combined rates rose from 476 per million (pm) to 973pm in Finland, followed by America 336 pm to 592 pm and UK 205 pm to 553 pm. Notable increases in numbers of deaths of 55-74-year-olds, below Western life-expectancy olds, were Austria 77%, Germany 52%, Sweden 48%, Finland 44%, America 39%, Japan 36% the UK 32% in just 16 years. Examples of major rises in Total neurological deaths was in Britain going from 24,601 to 103,550 and in America from 174,708 to 436,43, whilst Over75’s neurological deaths substantially outstripped population increases. Conclusions: Neurological death rates are accelerating at an unprecedented rate, challenging the Gompertzian hypothesis that these increases are primarily due demographics, strongly indicating multiple interactive environmental cause

    Covid-19 Pandemic: Lessons from Peak Years of Influenza & Suicide Deaths by Age in Ten Western Countries 1979-2016: An alert for psychiatry and children’s services

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    Background: The IMF fears the COVID-19 pandemic will create an economic down-turn matching the Great Depression. More recent recessions have led to physical and mental health problems including suicide deaths of young adults (15 - 34). We aim to identify risk patterns of mortality by age from influenza and suicide mortality in peak years from 1979 to 2016 to see if there are lessons to be learned for policy makers and psychiatric services. Method: Using WHO mortality data for 1979-2016 peak years of influenza deaths and suicides are identified in ten Western countries. Death rates per million in each age-band are calculated for both sexes and the percentage of the total deaths accruing in each of five age-bands for influenza and suicides. Ratios of influenza to suicide by age in regard to rates and percentages of deaths indicate differential risk mortality and morbidity patterns. Results: Of the ten country’s average Influenza deaths, 95% occurred in people over 55, including 80% - 85% for the over 75’s. Conversely it was 59% of suicides occurred in peoples aged <55 years. Young adults (15 - 34) influenza to suicide ratios were 1:12.1 and 35 - 54 years ratio 1:9.3. Discussion: IMF predicts major unemployment, which is likely to create mental health problems, including suicide as well as worsening child health outcomes linked to relative poverty. These wider inter-related factors should be considered by policy-makers and mental health services. The age patterns of risk of mortality point towards a cumulative summation of morbidity and mortality risks of the socio-economic consequences of the COVID pandemic

    Female chacma baboons form strong, equitable, and enduring social bonds

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    Analyses of the pattern of associations, social interactions, coalitions, and aggression among chacma baboons (Papio hamadryas ursinus) in the Okavango Delta of Botswana over a 16-year period indicate that adult females form close, equitable, supportive, and enduring social relationships. They show strong and stable preferences for close kin, particularly their own mothers and daughters. Females also form strong attachments to unrelated females who are close to their own age and who are likely to be paternal half-sisters. Although absolute rates of aggression among kin are as high as rates of aggression among nonkin, females are more tolerant of close relatives than they are of others with whom they have comparable amounts of contact. These findings complement previous work which indicates that the strength of social bonds enhances the fitness of females in this population and support findings about the structure and function of social bonds in other primate groups

    Frequency and Risk Indicators of Tooth Decay among Pregnant Women in France: A Cross-Sectional Analysis

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    INTRODUCTION: Little is known on the prevalence of tooth decay among pregnant women. Better knowledge of tooth decay risk indicators during pregnancy could help to develop follow-up protocols for women at risk, along with better prevention strategies. The aim of this study was to assess the frequency of tooth decay and the number of decayed teeth per woman in a large sample of pregnant women in France, and to study associated risk indicators. METHODS: A secondary cross-sectional analysis of data from a French multicentre case-control study was performed. The sample was composed of 1094 at-term women of six maternity units. A dental examination was carried out within 2 to 4 days post-partum. Socio-demographic and behavioural characteristics were obtained through a standardised interview with the women. Medical characteristics were obtained from the women's medical records. Risk indicators associated with tooth decay were identified using a negative binomial hurdle model. RESULTS: 51.6% of the women had tooth decay. The mean number of decayed teeth among women having at least one was 3.1 (s.d. = 2.8). Having tooth decay was statistically associated with lower age (aOR = 1.58, 95%CI [1.03,2.45]), lower educational level (aOR = 1.53, 95%CI [1.06,2.23]) and dental plaque (aOR = 1.75, 95%CI [1.27,2.41]). The number of decayed teeth was associated with the same risk indicators and with non-French nationality and inadequate prenatal care. DISCUSSION: The frequency of tooth decay and the number of decayed teeth among pregnant women were high. Oral health promotion programmes must continue to inform women and care providers about the importance of dental care before, during and after pregnancy. Future research should also assess the effectiveness of public policies related to oral health in target populations of pregnant women facing challenging social or economic situations

    The long lives of primates and the ‘invariant rate of ageing’ hypothesis

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    This work was supported by NIA P01AG031719 to J.W.V. and S.C.A., with additional support provided by the Max Planck Institute of Demographic Research and the Duke University Population Research Institute.Is it possible to slow the rate of ageing, or do biological constraints limit its plasticity? We test the ‘invariant rate of ageing’ hypothesis, which posits that the rate of ageing is relatively fixed within species, with a collection of 39 human and nonhuman primate datasets across seven genera. We first recapitulate, in nonhuman primates, the highly regular relationship between life expectancy and lifespan equality seen in humans. We next demonstrate that variation in the rate of ageing within genera is orders of magnitude smaller than variation in pre-adult and age-independent mortality. Finally, we demonstrate that changes in the rate of ageing, but not other mortality parameters, produce striking, species-atypical changes in mortality patterns. Our results support the invariant rate of ageing hypothesis, implying biological constraints on how much the human rate of ageing can be slowed.Publisher PDFPeer reviewe

    Remembering the City: Changing Conceptions of Community in Urban China

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    Adopting complimentary integrative research methodologies, this article examines changing conceptions of community amongst urban residents within the city of Suzhou, Jiangsu province, China. Whilst the impact of urban transformation from a macro-perspective, deploying large scale quantitative measures to capture resident perceptions within China’s mega-cities, has been addressed, there is something of a scholarly lacuna that adopts a micro-perspective to explore the nation-state’s smaller developing cities. Thus, through local residents’ past memories, ‘everyday’ experiences of (former) urban communities, and reflections on a particular way of life, we focus upon the subjective/affective meanings and memories attached to processes of urban change. We place emphasis on the manner in which residents make sense of socio-spatial transformations in relation to the (re)making of community, local social interaction, and a sense of belonging. Discussion centres on the affective and embodied notions of a particular way of life in (older) communities; sensory performances that were deemed difficult to replicate within modern development zones and the broader field of contemporary Chinese society
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