104 research outputs found
Are rises in Electro-Magnetic Field in the human environment, interacting with multiple environmental pollutions, the tripping point for increases in neurological deaths in the Western World?
Š 2019 Elsevier Ltd Whilst humans evolved in the earth's Electro-Magnetic-Field (EMF) and sun-light, both being essential to life but too much sun and we burn. What happens if background EMF rise to critical levels, coinciding with increasing environmental pollutants? Two of the authors can look back over 50 clinical years and appreciate the profound changes in human morbidity across a range of disparate conditions â autoimmune diseases, asthma, earlier cancer incidence and reduced male sperm counts. In particular have been increased autism, dyslexia, Attention Deficit Hyperactivity Disorder and neurological diseases, such as Amyotrophic Lateral Sclerosis, Multiple Sclerosis, Parkinson's Disease, Early Onset Dementia, Multiple System Atrophy and Progressive Supranuclear Palsy. What might have caused these changes-whilst genetic factors are taken as given, multiple environmental pollutants are associated with neurological disease although the mechanisms are unclear. The pace of increased neurological deaths far exceeds any Gompertzian explanation - that because people are living longer they are more likely to develop more age-related problems such as neurological disease. Using WHO global mortality categories of Neurological Disease Deaths (NDD) and Alzheimer's and Dementia deaths (Alz), updated June 2018, together they constitute Total Neurological Mortality (TNM), to calculate mortality rates per million for people aged 55â74 and for the over-75's in twenty-one Western countries. Recent increases in American people aged over-75's rose 49% from 1989 to 2015 but US neurological deaths increased five-fold. In 1989 based on Age-Standardised-Deaths-Rates America USA was 17th at 324 pm but rising to 539 pm became second highest. Different environmental/occupational factors have been found to be associated with neuro-degenerative diseases, including background EMF. We briefly explore how levels of EMF interact upon the human body, which can be described as a natural antennae and provide new evidence that builds upon earlier research to propose the following hypothesis. Based upon recent and new evidence we hypothesise that a major contribution for the relative sudden upsurge in neurological morbidity in the Western world (1989â2015), is because of increased background EMF that has become the tipping point-impacting upon any genetic predisposition, increasing multiple-interactive pollutants, such as rises in petro-chemicals, hormone disrupting chemicals, industrial, agricultural and domestic chemicals. The unprecedented neurological death rates, all within just twenty-five years, demand a re-examination of long-term EMF safety related to the increasing background EMF on human health. We do not wish to 'stop the modern worldâ, only make it safer
Two-Year Cohort of 88 Multiple System Atrophy Patientsâ Occupations and Incidence of Electric Shock and Head Injury: A Hypothesis Stimulating Pilot Study
Introduction: Multiple Systematic Atrophy (MSA) whose incidences have virtually doubled, in ⌠years (how many) coinciding with confirmed major rises in total neurological mortality in the developed world. The aetiology of neurological diseases is linked to various `Possible Occupations Linkedâ (POL) to neurological disease- Electronics and IT; Engineering, Chemicals, Solvents. Two inconsistent findings - electric shock and head injury have been reported by many MSA patients. This pilot study analyses differences between MSA patients and the general population in regard to occupation and incidence of electric shock and head injury. Methodology: A two-year cohort of MSA patients attending support groups completed a one page self-administered questionnaire. It explored age, sex, occupation and electric shock and head injury, contrasted with estimates in the General Public, occupations were determined from ONS data, from which odds ratios of patients and general population were calculated. Results: [Colin these figures are a bit puzzling but I am not a statistician] Of the 88 patients, 34% were aged <60; 56% occupations were POL compared to 24% in the regional population; one in 1.52 MSA patients reported head injury 1:1.52 and 1:3.26 electric shock. This yielded odd ratios of patients to general population of 1: 91.4 and 1: 589.9 respectively. Patents with Other occupations had significantly more trauma than POL patients. Discussion: Despite the limits of the study 34% of the cohort were relatively young for neurological disease, double the 'possible occupational linksâ to neurological disease than the general population and substantially higher trauma incidence. This pilot study indicates the need for a more focused analysis of possible tripping [? or is contributory better] factors in the aetiology of MSA
Acute Flaccid Myelitis-Possible Link with Electro-Magnetism? A Hypothesis Stimulating Study.
âWonder grows when knowledge failsâ (Francis
Bacon 1561-1626) A new polio-like condition mainly
affecting children (mean 5 years old) is being
observed, starting with viral and respiratory
symptoms, followed by a demyelination paralysis.
Known as Acute Flaccid Myelitis, first identified in
2010 in America, 28% to 95% of cases are associated
with Enterovirus EVD68. Yet EVD68 itself was
identified decades previously in China and the
Netherlands.
Prior to hospitalisation some children had no
evidence of neurological symptoms, hinting a possible
environmental trigger. Acute hospitals have multiple
sources of background Electro-Magnetic-Field
(EMF), some above recommended safety levels.
Hence the hypothesis âAre critical rises in human
background electromagnetism, interacting with other
environmental factors, possibly a casual factor, in
Acute Flaccid Myelitis? âThere is evidence that low
frequency EFM creates cellular oxidative stress
leading to neurodegeneration. Mechanisms are
unclear but could ubiquitous background EMF play a
role in childrenâs vulnerability to EVD68?
The context of the hypothesis is the evidence of
accelerating rates of neurological morbidity in the
21st Century and whether the range and multiplicity
of environmental factors are impacting upon an
immune-compromised childâs neurology. As health
environmental factors were ignored in the past, e.g.
smoking and asbestos, another possible environmental
linked anomaly is feared, though we note the recent
establishment of the UK Acute Flaccid Paralysis Task
Force in 2019. This hypothesis, whilst remaining
speculative, needs to be refuted through independent
research to ensure that AFM is not another childrenâs
neurological condition, which once were rare but now
becoming more commonplace
Neurological Deaths in the 21st Century in 21 Western Countries: Demographics or Environmental Causes
Introduction: There is evidence of rising neurological deaths in the Western world. This study examines any
changes during the 21st century to indicate whether the causes are primarily demographic or environmental.
Method: All data based upon WHO mortality rates per million (pm) for WHO mortality categories Nervous
Disease Deaths (NDD) and Alzheimer and Other Dementias Deaths (AlzD) to calculate a Combined
Neurological Mortality rate for people aged 55-74 Year Olds (lower than Western life-expectancy) and
AGE-STANDARDISED-DEATH-RATES (ASDR) (pm) for both sexes. Over75âs neurological deaths and
population numbers analyzed to determine if increased mortality mainly due to an ageing population.
Results: 55-74Year Olds: NDD rates were higher than AlzD in every country. Combined rates rose
substantially in ten countries, although Canadian and French rates fell. Total ASDR: NDD and AlzD
increased substantially in all countries. Highest combined rates rose from 476 per million (pm) to 973pm
in Finland, followed by America 336 pm to 592 pm and UK 205 pm to 553 pm. Notable increases in
numbers of deaths of 55-74-year-olds, below Western life-expectancy olds, were Austria 77%, Germany
52%, Sweden 48%, Finland 44%, America 39%, Japan 36% the UK 32% in just 16 years. Examples of
major rises in Total neurological deaths was in Britain going from 24,601 to 103,550 and in America from
174,708 to 436,43, whilst Over75âs neurological deaths substantially outstripped population increases.
Conclusions: Neurological death rates are accelerating at an unprecedented rate, challenging the
Gompertzian hypothesis that these increases are primarily due demographics, strongly indicating multiple
interactive environmental cause
Covid-19 Pandemic: Lessons from Peak Years of Influenza & Suicide Deaths by Age in Ten Western Countries 1979-2016: An alert for psychiatry and childrenâs services
Background: The IMF fears the COVID-19 pandemic will create an economic down-turn matching the Great Depression. More recent recessions
have led to physical and mental health problems including suicide deaths of
young adults (15 - 34). We aim to identify risk patterns of mortality by age
from influenza and suicide mortality in peak years from 1979 to 2016 to see if
there are lessons to be learned for policy makers and psychiatric services.
Method: Using WHO mortality data for 1979-2016 peak years of influenza
deaths and suicides are identified in ten Western countries. Death rates per
million in each age-band are calculated for both sexes and the percentage of
the total deaths accruing in each of five age-bands for influenza and suicides.
Ratios of influenza to suicide by age in regard to rates and percentages of
deaths indicate differential risk mortality and morbidity patterns. Results: Of
the ten countryâs average Influenza deaths, 95% occurred in people over 55,
including 80% - 85% for the over 75âs. Conversely it was 59% of suicides occurred in peoples aged <55 years. Young adults (15 - 34) influenza to suicide
ratios were 1:12.1 and 35 - 54 years ratio 1:9.3. Discussion: IMF predicts major unemployment, which is likely to create mental health problems, including suicide as well as worsening child health outcomes linked to relative poverty. These wider inter-related factors should be considered by policy-makers and mental health services. The age patterns of risk of mortality
point towards a cumulative summation of morbidity and mortality risks of the
socio-economic consequences of the COVID pandemic
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Building communities for student success: facilitating student belonging through online inductions
In 2022, The Open University in Wales launched a series of online induction events for new students, aiming to develop studentsⲠsense of belonging, provide an effective transition to the university, and ultimately, to support students to succeed.
A theory of change (ToC) model informed the design and evaluation of the induction events. This article presents the initial evaluation, using qualitative and quantitative data to test the assumptions underpinning the ToC and explore questions such as: are online induction events effective for developing a sense of belonging? Which students attended the events? What do we know about the subsequent academic performance of students who attended compared to those who did not?
The results suggest that well-designed online induction events can effectively foster a sense of belonging among students. However, when examining factors such as socio-demographic characteristics, certain groups of students appear less likely to participate. The authors emphasise the importance of using data to develop awareness of potential systemic barriers to engagement, and using these insights to remove barriers, address the specific needs of diverse student populations, and foster a more supportive and inclusive educational environment
Female chacma baboons form strong, equitable, and enduring social bonds
Analyses of the pattern of associations, social interactions, coalitions, and aggression among chacma baboons (Papio hamadryas ursinus) in the Okavango Delta of Botswana over a 16-year period indicate that adult females form close, equitable, supportive, and enduring social relationships. They show strong and stable preferences for close kin, particularly their own mothers and daughters. Females also form strong attachments to unrelated females who are close to their own age and who are likely to be paternal half-sisters. Although absolute rates of aggression among kin are as high as rates of aggression among nonkin, females are more tolerant of close relatives than they are of others with whom they have comparable amounts of contact. These findings complement previous work which indicates that the strength of social bonds enhances the fitness of females in this population and support findings about the structure and function of social bonds in other primate groups
Frequency and Risk Indicators of Tooth Decay among Pregnant Women in France: A Cross-Sectional Analysis
INTRODUCTION: Little is known on the prevalence of tooth decay among pregnant women. Better knowledge of tooth decay risk indicators during pregnancy could help to develop follow-up protocols for women at risk, along with better prevention strategies. The aim of this study was to assess the frequency of tooth decay and the number of decayed teeth per woman in a large sample of pregnant women in France, and to study associated risk indicators. METHODS: A secondary cross-sectional analysis of data from a French multicentre case-control study was performed. The sample was composed of 1094 at-term women of six maternity units. A dental examination was carried out within 2 to 4 days post-partum. Socio-demographic and behavioural characteristics were obtained through a standardised interview with the women. Medical characteristics were obtained from the women's medical records. Risk indicators associated with tooth decay were identified using a negative binomial hurdle model. RESULTS: 51.6% of the women had tooth decay. The mean number of decayed teeth among women having at least one was 3.1 (s.d. = 2.8). Having tooth decay was statistically associated with lower age (aOR = 1.58, 95%CI [1.03,2.45]), lower educational level (aOR = 1.53, 95%CI [1.06,2.23]) and dental plaque (aOR = 1.75, 95%CI [1.27,2.41]). The number of decayed teeth was associated with the same risk indicators and with non-French nationality and inadequate prenatal care. DISCUSSION: The frequency of tooth decay and the number of decayed teeth among pregnant women were high. Oral health promotion programmes must continue to inform women and care providers about the importance of dental care before, during and after pregnancy. Future research should also assess the effectiveness of public policies related to oral health in target populations of pregnant women facing challenging social or economic situations
The long lives of primates and the âinvariant rate of ageingâ hypothesis
This work was supported by NIA P01AG031719 to J.W.V. and S.C.A., with additional support provided by the Max Planck Institute of Demographic Research and the Duke University Population Research Institute.Is it possible to slow the rate of ageing, or do biological constraints limit its plasticity? We test the âinvariant rate of ageingâ hypothesis, which posits that the rate of ageing is relatively fixed within species, with a collection of 39 human and nonhuman primate datasets across seven genera. We first recapitulate, in nonhuman primates, the highly regular relationship between life expectancy and lifespan equality seen in humans. We next demonstrate that variation in the rate of ageing within genera is orders of magnitude smaller than variation in pre-adult and age-independent mortality. Finally, we demonstrate that changes in the rate of ageing, but not other mortality parameters, produce striking, species-atypical changes in mortality patterns. Our results support the invariant rate of ageing hypothesis, implying biological constraints on how much the human rate of ageing can be slowed.Publisher PDFPeer reviewe
Remembering the City: Changing Conceptions of Community in Urban China
Adopting complimentary integrative research methodologies, this article examines changing conceptions of community amongst urban residents within the city of Suzhou, Jiangsu province, China. Whilst the impact of urban transformation from a macro-perspective, deploying large scale quantitative measures to capture resident perceptions within Chinaâs mega-cities, has been addressed, there is something of a scholarly lacuna that adopts a micro-perspective to explore the
nation-stateâs smaller developing cities. Thus, through local residentsâ past memories, âeverydayâ experiences of (former) urban communities, and reflections on a particular way of life, we focus upon the subjective/affective meanings and memories attached to processes of urban change. We place emphasis on the manner in which residents make sense of socio-spatial transformations in relation to the (re)making of community, local social interaction, and a sense of belonging. Discussion centres on the affective and embodied notions of a particular way of life in (older) communities; sensory performances that were deemed difficult to replicate within modern development zones and the broader field of contemporary Chinese society
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