Detection of alteration associated with a porphyry copper deposit in southern Arizona

Computer processing of Landsat MSS data was performed using contrast stretching and band-to-band ratioing. A false color ratio composite picture showed color anomalies which coincided with known areas of alteration on and about Red Mountain. A helicopter survey of the study area was undertaken using a portable field reflectance spectrometer. One hundred fifty-six spectra were obtained in the 0.4 to 2.5 micrometer wavelength region. The spectra were digitized, and contour maps for 24 wavelength intervals were produced; no spectral anomalies were evident for the known altered areas. A contour map produced from the 1.6 and 2.2 micrometer ratio generally delineated the alteration areas. The 1.3, 1.6, and 2.2 micrometer wavelength data were canonically transformed using a transformation empirically derived from discriminant function analysis of altered and unaltered materials for the Goldfield, Nevada region, and a contour map was produced for the first canonical variable. The known areas of alteration were clearly defined on the contour map

Unresolved Unidentified Source Contribution to the Gamma-ray Background

The large majority of EGRET point sources remain without an identified low-energy counterpart, and a large fraction of these sources are most likely extragalactic. Whatever the nature of the extragalactic EGRET unidentified sources, faint unresolved objects of the same class must have a contribution to the diffuse extragalactic gamma-ray background (EGRB). Understanding this component of the EGRB, along with other guaranteed contributions from known sources, is essential if we are to use this emission to constrain exotic high-energy physics. Here, we follow an empirical approach to estimate whether a potential contribution of unidentified sources to the EGRB is likely to be important, and we find that it is. Additionally, we show how upcoming GLAST observations of EGRET unidentified sources, as well as of their fainter counterparts, can be combined with GLAST observations of the Galactic and extragalactic diffuse backgrounds to shed light on the nature of the EGRET unidentified sources even without any positional association of such sources with low-energy counterparts.Comment: 11 pages, 5 figures, submitted to Ap

The detection of geothermal areas from Skylab thermal data

Skylab-4 X-5 thermal data of the geysers area was analyzed to determine the feasibility of using midday Skylab images to detect geothermal areas. The hottest ground areas indicated on the Skylab image corresponded to south-facing barren or sparsely vegetated slopes. A geothermal area approximately 15 by 30 m coincided with one of the hottest areas indicated by Skylab. This area could not be unambiguously distinguished from the other areas which are believed to be hotter than their surroundings as a result of their topography, and micrometeorological conditions. A simple modification of a previous thermal model was performed and the predicted temperatures for the hottest slopes using representative values was in general agreement with the observed data. It is concluded that data from a single midday Skylab pass cannot be used to locate geothermal areas

1H, 13C, 15N backbone and IVL methyl group resonance assignment of the fungal β-glucosidase from Trichoderma reesei

β-glucosidases have received considerable attention due to their essential role in bioethanol production from lignocellulosic biomass. β-glucosidase can hydrolyse cellobiose in cellulose degradation and its low activity has been considered as one of the main limiting steps in the process. Large-scale conversions of cellulose therefore require high enzyme concentration which increases the cost. β-glucosidases with improved activity and thermostability are therefore of great commercial interest. The fungus Trichoderma reseei expresses thermostable cellulolytic enzymes which have been widely studied as attractive targets for industrial applications. Genetically modified β-glucosidases from Trichoderma reseei have been recently commercialised. We have developed an approach in which screening of low molecular weight molecules (fragments) identifies compounds that increase enzyme activity and are currently characterizing fragment-based activators of TrBgl2. A structural analysis of the 55 kDa apo form of TrBgl2 revealed a classical (α/β)8-TIM barrel fold. In the present study we present a partial assignment of backbone chemical shifts, along with those of the Ile (I)-Val (V)-Leu (L) methyl groups of TrBgl2. These data will be used to characterize the interaction of TrBgl2 with the small molecule activators

Ultrasound shear wave elastography and its association with rotator cuff tear characteristics

Background: Approximately 20-60% of rotator cuff repairs fail with higher failure rates in patients with larger or more chronic tears. Although MRI provides an objective estimate of tear size, it can only provide qualitative descriptions of tear chronicity. By contrast, ultrasound shear wave elastography (SWE) may assess tear chronicity by estimating tissue mechanical properties (ie, shear modulus). Furthermore, SWE imaging does not share many of the challenges associated with MRI (eg, high cost, risk of claustrophobia). Therefore, the objective of this study was to determine the extent to which estimated supraspinatus shear modulus is associated with conventional MRI-based measures of rotator cuff tear size and chronicity. Methods: Shear modulus was estimated using ultrasound SWE in two regions of the supraspinatus (intramuscular tendon, muscle belly) under two contractile conditions (passive, active) in 22 participants with full-thickness rotator cuff tears. The extent to which estimated supraspinatus shear modulus is associated with conventional MRI measures of tear size and chronicity was assessed using correlation coefficients and Kruskal-Wallis tests, as appropriate. Results: Estimated shear modulus was not significantly associated with anterior/posterior tear size (P \u3e .09), tear retraction (P \u3e .20), occupation ratio (P \u3e .11), or fatty infiltration (P \u3e .30) under any testing condition. Discussion: Although ultrasound SWE measurements have been shown to be altered in the presence of various tendinopathies, the findings of this study suggest the utility of ultrasound SWE in this population (ie, patients with a small to medium supraspinatus rotator cuff tear) before surgical rotator cuff repair remains unclear