The Action of Introvit A + WS and Monocalcium Phosphate in the Prevention of Vitamin and Mineral Deficiency of Infertility in Cows

This article describes the clinical signs, blood tests, and diagnosis of nutritional infertility in dairy cows

Clinical features and results of treatment of patients with coronavirus infection complicated by interstitial pneumonia, as well as with concurrent diseases in the Fergana Region of the Republic of Uzbekistan

To analyze the clinical features and treatment results, as well as concomitant diseases in patients with coronavirus infection complicated by interstitial pneumonia in the Fergana region of the Republic of Uzbekistan

Modern tools and methods for ensuring the accuracy of measurement results

Production of high-quality products and provision of modern production hightech processes requires establishing the accuracy of measurements by introducing modern methods and tools.Производство качественной продукции и обеспечение современных производственных высокотехнологичных процессов требует установления точности производимых измерений путем внедрения современных методов и средств

Exploring the antibacterial and dermatitis-mitigating properties of chicken egg white-synthesized zinc oxide nano whiskers

IntroductionZinc oxide nanoparticles (ZnO-NPs) have garnered considerable interest in biomedical research primarily owing to their prospective therapeutic implications in combatting pathogenic diseases and microbial infections. The primary objective of this study was to examine the biosynthesis of zinc oxide nanowhiskers (ZnO-NWs) using chicken egg white (albumin) as a bio-template. Furthermore, this study aimed to explore the potential biomedical applications of ZnO NWs in the context of infectious diseases.MethodsThe NWs synthesized through biological processes were observed using electron microscopy, which allowed for detailed examination of their characteristics. The results of these investigations indicated that the NWs exhibited a size distribution ranging from approximately 10 to 100 nm. Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy-energy dispersive X-ray spectroscopy (SEM-EDX) mapping analyses successfully corroborated the size, dimensions, and presence of biological constituents during their formation. In this study, XTT assay and confocal imaging were employed to provide evidence of the efficacy of ZnO-NWs in the eradication of bacterial biofilms. The target bacterial strains were Staphylococcus aureus and Escherichia coli. Furthermore, we sought to address pertinent concerns regarding the biocompatibility of the ZnO-NWs. This was achieved through comprehensive evaluation of the absence of cytotoxicity in normal HEK-293T and erythrocytes.ResultsThe findings of this investigation unequivocally confirmed the biocompatibility of the ZnO-NWs. The biosynthesized ZnO-NWs demonstrated a noteworthy capacity to mitigate the dermatitis-induced consequences induced by Staphylococcus aureus in murine models after a therapeutic intervention lasting for one week.DiscussionThis study presents a comprehensive examination of the biosynthesis of zinc oxide nanowhiskers (ZnO-NWs) derived from chicken egg whites. These findings highlight the considerable potential of biosynthesized ZnO-NWs as a viable option for the development of therapeutic agents targeting infectious diseases. The antibacterial efficacy of ZnO-NWs against both susceptible and antibiotic-resistant bacterial strains, as well as their ability to eradicate biofilms, suggests their promising role in combating infectious diseases. Furthermore, the confirmed biocompatibility of ZnO-NWs opens avenues for their safe use in biomedical applications. Overall, this research underscores the therapeutic promise of ZnO-NWs and their potential significance in future biomedical advancements

СЛУЧАЙ САРКОМЫ КАПОШИ У ЖЕНЩИНЫ СТАРЧЕСКОГО ВОЗРАСТА

The article presents an analysis of a clinical  case of a patient  of 76 years, describes the key links  in the pathogenesis of Kaposi’s  sarcoma  virus,  and  the  modern concept of participation in the pathogenesis of the disease. A feature of this clinical  observation was the  development of the  disease on the background of the functional immunosuppression, which developed because of old age. Besides the standard protocol of conducting a similar  profile  of patients therapy led to the development of side  effects. In turn,  the optimization of the therapeutic protocol  has  allowed to avoid  side  effects from the  treatment, continue therapy led  to  complete convalescence.В статье представлен анализ клинического случая у пациентки 76 лет,  описаны ключевые звенья патогенеза  саркомы  Капоши и современная концепция участия вируса в  патогенезе заболевания. Особенностью данного  клинического наблюдения явилось развитие заболевания на  фоне  функциональной иммуносупрессии, развившейся ввиду преклонного возраста. Кроме  того, терапия стандартного протокола ведения пациентов подобного профиля привела к развитию побочных эффектов. В свою очередь, оптимизация терапевтического протокола позволила избежать  побочных эффектов от  лечения, продолжить терапию и привела к полной реконвалесценции

Observation of a nuclear recoil peak at the 100 eV scale induced by neutron capture

Coherent elastic neutrino-nucleus scattering and low-mass Dark Matter detectors rely crucially on the understanding of their response to nuclear recoils. We report the first observation of a nuclear recoil peak at around 112 eV induced by neutron capture. The measurement was performed with a CaWO$_4$ cryogenic detector from the NUCLEUS experiment exposed to a $^{252}$Cf source placed in a compact moderator. The measured spectrum is found in agreement with simulations and the expected peak structure from the single-$\gamma$ de-excitation of $^{183}$W is identified with 3 $\sigma$ significance. This result demonstrates a new method for precise, in-situ, and non-intrusive calibration of low-threshold experiments

Innovative technologies to increase the fertility of irrigated soils and crop yield

The main feature of non-traditional fertilizers is that they have a complex composition. They are new-generation fertilizers that contain the nutrients plants need and are able to provide plants with mobile nutrients for a long time. The development of non-traditional fertilizers will create new resources of fertilizers from the waste products of industry, households, and agricultural sectors. With the use of non-traditional fertilizers, agricultural products of good quality are obtained; this prolongs their shelf life. The use of non-traditional fertilizers is an alternative to the negative effects of chemical fertilizers and pesticides. The article considers innovative technologies for increasing the fertility of irrigated soils and crop yields using non-traditional fertilizers produced from agricultural waste. Technology for making compost from waste and manure was developed; the influence of non-traditional fertilizers on the agrochemical properties of soil and cotton yields was revealed; the optimal rate of their application was determined

Clinical features and results of treatment of patients with coronavirus infection complicated by interstitial pneumonia, as well as with concurrent diseases in the Fergana Region of the Republic of Uzbekistan

To analyze the clinical features and treatment results, as well as concomitant diseases in patients with coronavirus infection complicated by interstitial pneumonia in the Fergana region of the Republic of Uzbekistan

STUDYING THE MECHANISM OF PROTECTIVE ACTION OF INHIBITED PAINT COATING

The article studies the diffusion of nitrobenzene as an inhibitor through the enamel coating EP-750, the calculation of the diffusion rate constant and diffusion coefficient is given in the article