9,607 research outputs found

    Data Analytics

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    This chapter sets out to illustrate the dictum that there is (almost) nothing new under the sun. More specifically, its goal is to make the unfamiliar familiar within the field of data analytics. The need for such a treatment can be gauged from the plethora of terms currently vying for attention in the contemporary data analysis landscape, which can be puzzling even for seasoned researchers. These terms include: data mining, data science, data analytics, machine learning, deep learning, neural networks, and artificial intelligence. Hybrid terms such as ‘big data analytics’ are also emerging. As for the current front-runner term, data analytics, the evidence provided by the number of search engine hits reveals multiple competing versions subdivided by application domains, ranging from business analytics and crime analytics, to performance analytics, visual analytics, and many more. There is also an emerging software sub-industry providing tools for data analytics, many of which are named after the company which originally developed them

    The non-existence of stable Schottky forms

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    Let AgSA_g^S be the Satake compactification of the moduli space AgA_g of principally polarized abelian gg-folds and MgSM_g^S the closure of the image of the moduli space MgM_g of genus gg curves in AgA_g under the Jacobian morphism. Then AgSA_g^S lies in the boundary of Ag+mSA_{g+m}^S for any mm. We prove that Mg+mSM_{g+m}^S and AgSA_g^S do not meet transversely in Ag+mSA_{g+m}^S, but rather that their intersection contains the mmth order infinitesimal neighbourhood of MgSM_g^S in AgSA_g^S. We deduce that there is no non-trivial stable Siegel modular form that vanishes on MgM_g for every gg. In particular, given two inequivalent positive even unimodular quadratic forms PP and QQ, there is a curve whose period matrix distinguishes between the theta series of PP and QQ.Comment: Corrected version, using Yamada's correct version of Fay's formula for the period matrix of a certain degenerating family of curves. To appear in Compositio Mathematic

    The two sided parsec scale structure of the Low Luminosity Active Galactic Nucleus in NGC 4278

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    We present new Very Long Baseline Interferometry observations of the LINER galaxy NGC 4278. The observations were taken with the Very Long Baseline Array (VLBA) and a single antenna of the Very Large Array (VLA) at 5 GHz and 8.4 GHz and have a linear resolution of <0.1 pc. Our radio data reveal a two sided structure, with symmetric S-shaped jets emerging from a flat spectrum core. We fit the jet brightness with gaussian components, which we identify from a previous observation taken five years before. By comparing the positions of the components in the two epochs, we measure motions between 0.45 +/- 0.14 and 3.76 +/- 0.65 mas, corresponding to apparent velocities < 0.2c, and to ages in the range 8.3 - 65.8 years. Assuming that the radio morphology is intrinsically symmetric and its appearance is governed by Doppler beaming effects, we find that NGC4278 has mildly relativistic jets (beta ~ 0.75), closely aligned to the line-of-sight (2 degrees < theta < 4 degrees). Alternatively, the source could be oriented at a larger angle and asymmetries could be related to the jet interaction with the surrounding medium. We also present new simultaneous VLA observations between 1.4 and 43 GHz, and a 5 GHz light curve between 1972 and 2003. The radio spectrum can be fit by a relatively steep power-law (alpha = 0.54). We find significant variability at 5 GHz. All these arguments indicate that the radiation from NGC 4278 is emitted via the synchrotron process by relativistic particles accelerated by a supermassive black hole. Despite a much lower power, this is the same process that takes place in ordinary radio loud AGNs.Comment: 29 pages, 9 figures, ApJ accepte

    Circuit and plasticity defects in the developing somatosensory cortex of FMR1 knock-out mice

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    Silencing of the Fmr1 gene causes fragile X syndrome. Although defects in synaptic plasticity in the cerebral cortex have been linked to cognitive impairments in Fmr1 knock-out (ko) mice, the specific cortical circuits affected in the syndrome are unknown. Here, we investigated the development of excitatory projections in the barrel cortex of Fmr1 ko mice. In 2-week-old Fmr1 ko mice, a major ascending projection connecting layer 4 (L4) to L3 (L4-->L3), was defective in multiple and independent ways: its strength was reduced, caused by a lower connection probability; the axonal arbors of L4 cells were spatially diffuse in L2/3; the L4-->L3 projection did not show experience-dependent plasticity. By 3 weeks, the strength of the L4-->L3 projection was similar to that of wild type. Our data indicate that Fmr1 shapes sensory cortical circuits during a developmental critical period

    Blood rheology, cardiovascular risk factors, and cardiovascular disease: The West of Scotland Coronary Prevention Study

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    The West of Scotland Coronary Prevention Study (WOSCOPS) showed that pravastatin reduced the risk of coronary heart disease (CHD) events in 6,595 middle-aged hypercholesterolaemic men aged 45-64 years without prior myocardial infarction followed for an average of 4.9 years. We hypothesised prospectively (a) that baseline levels of haemorheological variables were related to baseline and incident CHD and to mortality; and (b) that reduction in lipoproteins by pravastatin would lower plasma and blood viscosity, a potential contributory mechanism to CHD events. We therefore studied plasma and blood viscosity, fibrinogen, haematocrit, and blood cell counts at baseline and 1 year. At baseline, plasma and blood viscosity were related to risk factors, CHD measures, and claudication. On univariate analysis, baseline levels of all rheological variables (except platelet count) were related to incident CHD; CHD mortality; and total mortality. On multivariate analysis including baseline CHD and risk factors, plasma and blood viscosity, haematocrit and white cell count each remained significantly associated with incident CHD; while fibrinogen remained an independent predictor of mortality (all p&lt;0.03). After one year, lipoprotein reduction by pravastatin was associated with significant reductions (about one quarter of a standard deviation) in plasma viscosity (mean difference 0.02 mPa.s, p&lt;0.001) and in blood viscosity (mean difference 0.06 mPa.s, p&lt;0.001), but was not associated with significant changes in other rheological variables. We therefore suggest that pravastatin therapy, which reduces elevated lipoproteins in hypercholesterolaemic men, may lower risks of CHD and mortality partly by lowering plasma and blood viscosity. Further studies are required to test this hypothesis
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