Investigation of ejector re-compression absorption refrigeration cycle

This thesis describes a theoretical and experimental investigation of the ejector re-compression lithium bromide absorption refrigeration cycle. In this novel cycle, a steam ejector is used to enhance the concentration process by compressing the vapour to a state that it can be used to re-heat the solution from where it was evolved. Since this cycle recovers the heat otherwise wasted in a conventional absorption cycle, the energy performance of the cycle is improved. The theoretical study shows that the improvement of the efficiency is proportional to the performance of the steam ejector. A COP of 1.013 was achieved from the experiment in this investigation. The novel cycle does not only improve the energy efficiency but also avoids the corrosion that will happen when high temperature heat sources are used to drive a lithium bromide absorption refrigerator. The steam ejector in the novel cycle acts as an efficient temperature converter in acceptance of different temperature heat sources, which reduces the energy loss when the temperature difference between the solution and the heat source is big. Therefore, the solution temperature can be set to a low level while the heat source temperature is high. This is significant to avoid the corrosion of lithium bromide solution at high temperature. Furthermore, the construction of the machine based on the novel cycle is simpler than that based on the conventional double-effect cycle. This refrigerator will be more reliable and have a lower initial capital cost. The cycle was investigated comprehensively in this thesis. In the theoretical study, a mathematical model for this novel cycle was established. The theoretical study reveals the operation characteristics and the factors that affect the energy efficiency of the cycle as well as how to design a refrigerator based on the novel cycle. In the experimental study, a concept-approved refrigerator was manufactured and tested. The part-load performance of the novel cycle was investigated from the experiment. The theoretical results had a good agreement with the experimental ones. NB. This ethesis has been created by scanning the typescript original and contains some inaccuracies. In case of difficulty, please refer to the original text

Investigation of ejector re-compression absorption refrigeration cycle

This thesis describes a theoretical and experimental investigation of the ejector re-compression lithium bromide absorption refrigeration cycle. In this novel cycle, a steam ejector is used to enhance the concentration process by compressing the vapour to a state that it can be used to re-heat the solution from where it was evolved. Since this cycle recovers the heat otherwise wasted in a conventional absorption cycle, the energy performance of the cycle is improved. The theoretical study shows that the improvement of the efficiency is proportional to the performance of the steam ejector. A COP of 1.013 was achieved from the experiment in this investigation. The novel cycle does not only improve the energy efficiency but also avoids the corrosion that will happen when high temperature heat sources are used to drive a lithium bromide absorption refrigerator. The steam ejector in the novel cycle acts as an efficient temperature converter in acceptance of different temperature heat sources, which reduces the energy loss when the temperature difference between the solution and the heat source is big. Therefore, the solution temperature can be set to a low level while the heat source temperature is high. This is significant to avoid the corrosion of lithium bromide solution at high temperature. Furthermore, the construction of the machine based on the novel cycle is simpler than that based on the conventional double-effect cycle. This refrigerator will be more reliable and have a lower initial capital cost. The cycle was investigated comprehensively in this thesis. In the theoretical study, a mathematical model for this novel cycle was established. The theoretical study reveals the operation characteristics and the factors that affect the energy efficiency of the cycle as well as how to design a refrigerator based on the novel cycle. In the experimental study, a concept-approved refrigerator was manufactured and tested. The part-load performance of the novel cycle was investigated from the experiment. The theoretical results had a good agreement with the experimental ones. NB. This ethesis has been created by scanning the typescript original and contains some inaccuracies. In case of difficulty, please refer to the original text

An experimental investigation of a micro-tubular SOFC membrane-separated liquid desiccant dehumidification and cooling tri-generation system

This paper reports the results of experimental work carried out on a micro-tubular solid oxide fuel cell tri-generation systemthat uses the waste heat from the fuel cell for dehumidification and cooling though the integration of an open cycle liquid desiccant dehumidification and cooling system. The experimental results demonstrate regeneration of the potassium formate solution using the thermal output from the SOFC in the first of its kind tri-generation system. Optimisation has shown that a 2.2L.min-1 regenerator desiccant volumetric flow facilitates best performance.When integrated with the micro-SOFC, the open cycle desiccant system demonstrates a COP of approaching 0.7, an encouraging value for a waste heat driven cooling system of this capacity. A tri-generation performance analysis is presented which serves to demonstrate the novel system operating in a building. The system achieved an electrical efficiency of 11% and regeneration efficiency of approximately 37%. The electrical efficiency is lower than that predicted by the company supplying the micro-tubular SOFC, because the unit suffered sulphur poisoning during preliminary tests. The electrical power output decreased from 250W to 150W, which reduced the electrical efficiency from around 18% to 11% and the overall efficiency from approximately 45% to just over 37%. Low temperature (33-36°C) regeneration was demonstrated

PRL-3 promotes the motility, invasion, and metastasis of LoVo colon cancer cells through PRL-3-integrin β1-ERK1/2 and-MMP2 signaling

<p>Abstract</p> <p>Background</p> <p>Phosphatase of regenerating liver-3 (PRL-3) plays a causative role in tumor metastasis, but the underlying mechanisms are not well understood. In our previous study, we observed that PRL-3 could decrease tyrosine phosphorylation of integrin β1 and enhance activation of ERK1/2 in HEK293 cells. Herein we aim to explore the association of PRL-3 with integrin β1 signaling and its functional implications in motility, invasion, and metastasis of colon cancer cell LoVo.</p> <p>Methods</p> <p>Transwell chamber assay and nude mouse model were used to study motility and invasion, and metastsis of LoVo colon cancer cells, respectively. Knockdown of integrin β1 by siRNA or lentivirus were detected with Western blot and RT-PCR. The effect of PRL-3 on integrin β1, ERK1/2, and MMPs that mediate motility, invasion, and metastasis were measured by Western blot, immunofluorencence, co-immunoprecipitation and zymographic assays.</p> <p>Results</p> <p>We demonstrated that PRL-3 associated with integrin β1 and its expression was positively correlated with ERK1/2 phosphorylation in colon cancer tissues. Depletion of integrin β1 with siRNA, not only abrogated the activation of ERK1/2 stimulated by PRL-3, but also abolished PRL-3-induced motility and invasion of LoVo cells in vitro. Similarly, inhibition of ERK1/2 phosphorylation with U0126 or MMP activity with GM6001 also impaired PRL-3-induced invasion. In addition, PRL-3 promoted gelatinolytic activity of MMP2, and this stimulation correlated with decreased TIMP2 expression. Moreover, PRL-3-stimulated lung metastasis of LoVo cells in a nude mouse model was inhibited when integrin β1 expression was interfered with shRNA.</p> <p>Conclusion</p> <p>Our results suggest that PRL-3's roles in motility, invasion, and metastasis in colon cancer are critically controlled by the integrin β1-ERK1/2-MMP2 signaling.</p

An experimental investigation on the effect of ferrofluids on the efficiency of novel parabolic trough solar collector under laminar flow conditions

The paper is related to the use of magnetic nanofluids (ferrofluids) in a direct absorption solar parabolic trough collectors enhances thermal efficiency compared to conventional solar collectors. By applying the right magnetic intensity and magnetic field direction, the thermal conductivity of the fluid increased higher than typical nanofluids. Moreover, the ferrofluids exhibit excellent optical properties. The external magnetic source is installed to alter the thermos-physical properties of the fluid, and the absorber tube does not have selective surface allowing ferrofluids to absorb the incoming solar irradiance directly. In this paper, an experimental investigation of the performance of direct absorption solar collector using ferrofluids as an absorber. Various nanoparticle concentrations 0% to 1vol% at the operational temperatures between 19°C and 40°C were used in the current study. The results show that using ferrofluids as a heat transfer fluid increases the efficiency of solar collectors. In the presence of the external magnetic field, the solar collector efficiency increases to the maximum, 25% higher than the conventional parabolic trough. At higher temperatures, the ferrofluids show much better efficiency than conventional heat transfer fluid. The study indicated that nanofluids, even of low-content, have good absorption of solar radiation, and can improve the outlet temperatures and system efficiencies

Simultaneous Extraction and Identification of Phenolic Compounds in Anoectochilus roxburghii Using Microwave-Assisted Extraction Combined with UPLC-Q-TOF-MS/MS and Their Antioxidant Activities

This study used MAE and RSM to extract phenolic compounds from Anoectochilus roxburghii, and the optimum conditions defined by the model to give an optimum yield of 1.31%. The antioxidant activity in vitro showed when the concentration of phenolic compounds was reached 1 mg mL-1, the clearance rates were 82.58% for DPPH and 97.62% for ABTS+. In vivo antioxidant experiments used D-galactose to build oxidative damage in healthy Kunming mice. The result showed that the extractions of A. roxburghii can improve the antioxidant ability and the medium and low dose groups had better ability to scavenge free radicals. The UPLC-Q-TOF-MS/MS was developed to identify 21 kinds of phenolic compounds by molecular mass, ms/ms fragmentation, as well as retention time. The result showed that the phenolic compounds of A. roxburghii had significant potential as a natural antioxidant to promote health and to reduce the risk of disease

An experimental study of a novel integrated desiccant air conditioning system for building applications

To date, the application of liquid desiccant air conditioning systems in built environment applications, particularly small scale, has been limited. This is primarily due to large system size and complexity, issues of desiccant solution leakage and carry-over and equipment corrosion. As a result, a novel integrated desiccant air conditioning system (IDCS) has been developed. The system combines the regenerator, dehumidifier and evaporative inter-cooler into a single membrane based heat and mass exchanger. This paper presents an evaluation, based on experimental data, of the novel IDCS operating with a potassium formate (CHKO2) desiccant working fluid. A range of tests have been completed to characterise the performance of the dehumidifier, regenerator and complete IDCS. Cooling output in the range of 570 to 1362W and dehumidifier effectiveness in the range of 30 to 47% are presented. An issue encountered has been an imbalance between moisture removal rate in the dehumidifier and moisture addition rate in the regenerator. As a result, an adjusted thermal COP (COPth,adj) value has been calculated. COPth,adj values of 1.26 have been achieved with an average of 0.72. Electrical COP (COPel) values of 3.67 have been achieved with an average of 2.5. The work demonstrates that the novel IDCS concept is viable and has provided progressto the field of liquid desiccant air conditioning technology for building applications. Further work is required in order to address the main issue of mass imbalance between the dehumidifier and regenerator

Emission and economic performance assessment of a solid oxide fuel cell micro-combined heat and power system in a domestic building

Combined heat and power (CHP) is a promising technological configuration for reducing energy consumption and increasing energy security in the domestic built environment. Fuel cells, on account of their: high electrical efficiency, low emissions and useful heat output have been identified as a key technological option for improving both building energy efficiency and reducing emissions in domestic CHP applications. The work presented in this paper builds upon results currently reported in the literature of fuel cells operating in domestic building applications, with an emission and economic performance assessment of a real, commercially available SOFC mCHP system operating in a real building; under a UK context. This paper aims to assess the emission and economic performance of a commercially available solid oxide fuel cell (SOFC) mCHP system, operating at The University of Nottingham's Creative Energy Homes. The performance assessment evaluates, over a one year period, the associated carbon (emission assessment) and operational costs (economic assessment) of the SOFC mCHP case compared to a ‘base case’ of grid electricity and a highly efficient gas boiler. Results from the annual assessment show that the SOFC mCHP system can generate annual emission reductions of up to 56% and cost reductions of 177% compared to the base case scenario. However support mechanisms such as; electrical export, feed in tariff and export tariff, are required in order to achieve this, the results are significantly less without. A net present value (NPV) analysis shows that the base case is still more profitable over a 15 year period, even though the SOFC mCHP system generates annual revenue; this is on account of the SOFC's high capital cost. In summary, grid interaction and incubator support is essential for significant annual emission and cost reductions compared to a grid electricity and gas boiler scenario. Currently capital cost is the greatest barrier to the economic viability of the system

Assessment of a novel solid oxide fuel cell tri-generation system for building applications

The paper provides a performance analysis assessment of a novel solid oxide fuel cell (SOFC) liquid desiccant tri-generation system for building applications. The work presented serves to build upon the current literature related to experimental evaluations of SOFC tri-generation systems, particularly in domestic built environment applications. The proposed SOFC liquid desiccant tri-generation system will be the first-of-its-kind. No research activity is reported on the integration of SOFC, or any fuel cell, with liquid desiccant air conditioning in a tri-generation system configuration. The novel tri-generation system is suited to applications that require simultaneous electrical power, heating and dehumidification/cooling. There are several specific benefits to the integration of SOFC and liquid desiccant air conditioning technology, including; very high operational electrical efficiencies even at low system capacities and the ability to utilise low-grade thermal energy in a (useful) cooling process. Furthermore, the novel tri-generation system has the potential to increase thermal energy utilisation and thus the access to the benefits achievable from on-site electrical generation, primarily; reduced emissions and operating costs. Using empirical SOFC and liquid desiccant component data, an energetic, economic and environmental performance analysis assessment of the novel system is presented. Significant conclusions from the work include: (1) SOFC and liquid desiccant are a viable technological pairing in the development of an efficient and effective tri-generation system. High tri-generation efficiencies in the range of 68-71% are attainable. (2) The inclusion of liquid desiccant provides an efficiency increase of 9-15% compared to SOFC electrical operation only, demonstrating the potential of the system in building applications that require simultaneous electrical power, heating and/or dehumidification/cooling. (3) Compared to an equivalent base case system, the novel tri-generation system is currently only economically viable with a government’s financial support. SOFC capital cost and stack replacement are the largest inhibitors to economic viability. Environmental performance is closely linked to electrical emission factor, and thus performance is heavily country dependent. (4) The economic and environmental feasibility of the novel tri-generation system will improve with predicted SOFC capital cost reductions and the transition to clean hydrogen production

Fuel cell technology for domestic built environment applications: state of-the-art review

Fuel cells produce heat when generating electricity, thus they are of particular interest for combined heat and power (CHP) and combined cooling heat and power (CCHP) applications, also known as tri-generation systems. CHP and tri-generation systems offer high energy conversion efficiency and hence the potential to reduce fuel costs and CO2 emissions. This article serves to provide a state-of-the-art review of fuel cell technology operating in the domestic built environment in CHP and tri-generation system applications. The review aims to carry out an assessment of the following topics: (1) the operational advantages fuel cells offer in CHP and tri-generation system configurations, specifically, compared to conventional combustion-based technologies such as Stirling engines, (2) how decarbonisation, running cost and energy security in the domestic built environment may be addressed through the use of fuel cell technology, and (3) what has been done to date and what needs to be done in the future. The article commences with a review of fuel cell technology, then moves on to examine fuel cell CHP systems operating in the domestic built environment, and finally explores fuel cell tri-generation systems in domestic built environment applications. The article concludes with an assessment of the present development of, and future challenges for, domestic fuel cells operating in CHP and tri-generation systems. As fuel cells are an emergent technology the article draws on a breadth of literature, data and experience, mostly from the United Kingdom, Germany, Japan, America and Australia. Fuel cells are a technology of the future here today, providing a change in the way heat and power are supplied to end users. Fuel cells operating in CHP and tri-generation systems in domestic built environment applications could finally provide the means by which energy generation can transfer from centralised to decentralised locales in a sustainable and effective manner