424 research outputs found

    BAICE Thematic Forum:Challenging deficit discourses in international education and development

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    Research and policy in international education has o en been framed in terms of a deficit discourse. For instance, policy debates on women’s literacy and education have begun by positioning women as a group who need to ‘catch up’ on certain skills in order to become more active in development. Rather than recognising the skills and knowledge that participants already have and prac se in their everyday lives, researchers who adopt this deficit perspective on learning and education may find that the research agenda and questions will already be shaped to a large extent by the providers’/ policy makers’ standpoint. This BAICE Thematic Forum aimed to deepen understanding around how deficit discourses have shaped the questions and objectives of international educational research. As well as deconstructing and gaining greater knowledge into why and how these dominant deficit discourses have influenced the research agenda, we also set out to investigate and propose alternative conceptual models through two linked seminars. The seminars were intended to explore and challenge dominant deficit discourses that have shaped the way researchers/policy makers look at specific groups in development and thematic policy areas

    Fasciola hepatica:The therapeutic potential of a worm secretome

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    The success of helminth parasites is partly related to their ability to modulate host immune responses towards an anti-inflammatory/regulatory phenotype. This ability resides with the molecules contained in the secretome of various helminths that have been shown to interact with host immune cells and influence their function. Consequently, there exists a unique opportunity to exploit these molecules for the prophylactic and therapeutic treatment of human pro- and auto-inflammatory disorders (for example septic shock, transplant rejection and autoimmune disease). In this review, we describe the mechanisms used by the trematode parasite, Fasciola hepatica, to modulate the immune responses of its host and discuss the potent immune-modulatory effects of three individual molecules within the secretome; namely cathepsin L1, peroxiredoxin and helminth defence molecule. With a focus on the requirements from industry, we discuss the strategies by which these molecules may be clinically developed to control human immune responses in a way that is conducive to the prevention of immune-mediated diseases

    New Theories and Methods for Screen-Centred Interfaces: A Pilot Study

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    There is an urgent need to examine the ways in which screen-centred interfaces present images and encode and decode meaning, identity, and culture. This project is an interdisciplinary collaboration by four researchers at the University of Regina and builds on our work on screen-centred interfaces in our respective disciplines of cognitive psychology, literary studies, media studies, and software systems engineering. The fundamental goals of our collaborative project are to engage interdisciplinary means and perspectives to systematically develop effective methodologies to measure cognitive processes, aesthetic effects, and software and hardware efficacy of the new and developing digital media. In this project/pilot study we intend to select a series of media fragments that include poetic, visual, and language texts, as well as those that combine these features, and present them on a variety of screen-centred interfaces to explore their cognitive and aesthetic effects and features. &nbsp

    Ozone loss derived from balloon-borne tracer measurements and the SLIMCAT CTM

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    Balloon-borne measurements of CFC-11 (on flights of the DIRAC in situ gas chromatograph and the DESCARTES grab sampler), ClO and O3 were made during the 1999/2000 winter as part of the SOLVE-THESEO 2000 campaign. Here we present the CFC-11 data from nine flights and compare them first with data from other instruments which flew during the campaign and then with the vertical distributions calculated by the SLIMCAT 3-D CTM. We calculate ozone loss inside the Arctic vortex between late January and early March using the relation between CFC-11 and O3 measured on the flights, the peak ozone loss (1200 ppbv) occurs in the 440–470 K region in early March in reasonable agreement with other published empirical estimates. There is also a good agreement between ozone losses derived from three independent balloon tracer data sets used here. The magnitude and vertical distribution of the loss derived from the measurements is in good agreement with the loss calculated from SLIMCAT over Kiruna for the same days

    Low reservoir ages for the surface ocean from mid-Holocene Florida corals

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    Author Posting. © American Geophysical Union, 2008. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Paleoceanography 23 (2008): PA2209, doi:10.1029/2007PA001527.The 14C reservoir age of the surface ocean was determined for two Holocene periods (4908–4955 and 3008–3066 calendar (cal) B.P.) using U/Th-dated corals from Biscayne National Park, Florida, United States. We found that the average reservoir ages for these two time periods (294 ± 33 and 291 ± 27 years, respectively) were lower than the average value between A.D. 1600 and 1900 (390 ± 60 years) from corals. It appears that the surface ocean was closer to isotopic equilibrium with CO2 in the atmosphere during these two time periods than it was during recent times. Seasonal ÎŽ 18O measurements from the younger coral are similar to modern values, suggesting that mixing with open ocean waters was indeed occurring during this coral's lifetime. Likely explanations for the lower reservoir age include increased stratification of the surface ocean or increased Δ14C values of subsurface waters that mix into the surface. Our results imply that a more correct reservoir age correction for radiocarbon measurements of marine samples in this location from the time periods ∌3040 and ∌4930 cal years B.P. is ∌292 ± 30 years, less than the canonical value of 404 ± 20 years.NSF Chemical Oceanography program provided monetary support under grants OCE-9711326, OCE-0137207, and OCE-0551940 (to ERMD)
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