847 research outputs found
Experimental characterization of gasoline sprays under highly evaporating conditions
An experimental investigation of multistream gasoline sprays under highly evaporating conditions is carried out in this paper. Temperature increase of fuel and low engine pressure could lead to flash boiling. The spray shape is normally modified significantly under flash boiling conditions. The spray plumes expansion along with reduction in the axial momentum causes the jets to merge and creates a low-pressure area below the injector’s nozzle. These effects initiate the collapse of spray cone and lead to the formation of a single jet plume or a big cluster like structure. The collapsing sprays reduces exposed surface and therefore they last longer and subsequently penetrate more. Spray plume momentum increase, jet plume reduction and spray target widening could delay or prevent the closure condition and limit the penetration (delayed formation of the cluster promotes evaporation). These spray characteristics are investigated experimentally using shadowgraphy, for five and six hole injectors, under various boundary conditions. Six hole injectors produce more collapsing sprays in comparison to five hole injector due to enhanced jet to jet interactions. The spray collapse tendency reduces with increase in injection pressure due high axial momentum of spray plumes. The spray evaporation rates of five hole injector are observed to be higher than six hole injectors. Larger spray cone angles of the six hole injectors promote less penetrating and less collapsing sprays
Natural convection in polyethylene glycol based molybdenum disulfide nanofluid with thermal radiation, chemical reaction and ramped wall temperature
© 2018 International Information and Engineering Technology Association. All Rights Reserved. The aim of this study is to investigate the unsteady magnetohydrodynamic (MHD) flow of Casson nanofluid over an infinite oscillating vertical plate with ramped wall temperature. The effects of porosity, thermal radiation and first order chemical reaction have been considered. Polyethylene glycol (PEG) is chosen as base fluid which contained molybdenum disulfide (MoS 2 ) nanoparticles. The Laplace transform technique is applied to the momentum, energy and concentration equations to obtain the closed form solutions. The obtained solutions are for both cases ramped and isothermal boundary conditions and compared graphically. From graphical analysis, it is observed that for isothermal plate, the magnitude of velocity, temperature and concentration profiles are greater than ramped wall temperature. Skin-friction, Nusselt number and Sherwood number are evaluated and presented in tabular forms. The effects of various embedded parameters on velocity, temperature and concentration profiles are discussed graphically
Boundary Peeling: Outlier Detection Method Using One-Class Peeling
Unsupervised outlier detection constitutes a crucial phase within data
analysis and remains a dynamic realm of research. A good outlier detection
algorithm should be computationally efficient, robust to tuning parameter
selection, and perform consistently well across diverse underlying data
distributions. We introduce One-Class Boundary Peeling, an unsupervised outlier
detection algorithm. One-class Boundary Peeling uses the average signed
distance from iteratively-peeled, flexible boundaries generated by one-class
support vector machines. One-class Boundary Peeling has robust hyperparameter
settings and, for increased flexibility, can be cast as an ensemble method. In
synthetic data simulations One-Class Boundary Peeling outperforms all state of
the art methods when no outliers are present while maintaining comparable or
superior performance in the presence of outliers, as compared to benchmark
methods. One-Class Boundary Peeling performs competitively in terms of correct
classification, AUC, and processing time using common benchmark data sets
Experiment and Prediction of Ablation Depth in Excimer Laser Micromachining of Optical Polymer Waveguides
Extending the data transfer rates through dense interconnections at inter- and intraboard levels is a well-established technique especially in consumer electronics at the expense of more cross talk, electromagnetic interference (EMI), and power dissipation. Optical transmission using optical fibre is practically immune to the aforementioned factors. Among the manufacturing methods, UV laser ablation using an excimer laser has been repeatedly demonstrated as a suitable technique to fabricate multimode polymer waveguides. However, the main challenge is to precisely control and predict the topology of the waveguides without the need for extensive characterisation which is both time consuming and costly. In this paper, the authors present experimental results of investigation to relate the fluence, scanning speed, number of shots, and passes at varying pulse repetition rate with the depth of ablation of an acrylate-based photopolymer. The depth of ablation essentially affects total internal reflection and insertion loss, and these must be kept at minimum for a successful optical interconnection on printed circuit boards. The results are then used to predict depth of ablation for this material by means of adaptive neurofuzzy inference system (ANFIS) modelling. The predicted results, with a correlation of 0.9993, show good agreement with the experimental values. This finding will be useful in better predictions along with resource optimisation and ultimately helps in reducing cost of polymer waveguide fabrication.</jats:p
Effects of air pollution and the introduction of the London Low Emission Zone on the prevalence of respiratory and allergic symptoms in schoolchildren in East London: a sequential cross-sectional study
The adverse effects of traffic-related air pollution on children’s respiratory health have been widely reported, but few studies have evaluated the impact of traffic-control policies designed to reduce urban air pollution. We assessed associations between traffic-related air pollutants and respiratory/allergic symptoms amongst 8–9 year-old schoolchildren living within the London Low Emission Zone (LEZ). Information on respiratory/allergic symptoms was obtained using a parent-completed questionnaire and linked to modelled annual air pollutant concentrations based on the residential address of each child, using a multivariable mixed effects logistic regression analysis. Exposure to traffic-related air pollutants was associated with current rhinitis: NOx (OR 1.01, 95% CI 1.00–1.02), NO2 (1.03, 1.00–1.06), PM10 (1.16, 1.04–1.28) and PM2.5 (1.38, 1.08–1.78), all per μg/m3 of pollutant, but not with other respiratory/allergic symptoms. The LEZ did not reduce ambient air pollution levels, or affect the prevalence of respiratory/allergic symptoms over the period studied. These data confirm the previous association between traffic-related air pollutant exposures and symptoms of current rhinitis. Importantly, the London LEZ has not significantly improved air quality within the city, or the respiratory health of the resident population in its first three years of operation. This highlights the need for more robust measures to reduce traffic emissions
Self-management support interventions for stroke survivors: a systematic meta-review
There is considerable policy interest in promoting self-management in patients with long-term conditions, but it remains uncertain whether these interventions are effective in stroke patients.Systematic meta-review of the evidence for self-management support interventions with stroke survivors to inform provision of healthcare services.We searched MEDLINE, EMBASE, CINAHL, PsychINFO, AMED, BNI, Database of Abstracts of Reviews for Effectiveness, and Cochrane Database of Systematic Reviews for systematic reviews of self-management support interventions for stroke survivors. Quality was assessed using the R-AMSTAR tool, and data extracted using a customised data extraction form. We undertook a narrative synthesis of the reviews' findings.From 12,400 titles we selected 13 systematic reviews (published 2003-2012) representing 101 individual trials. Although the term 'self-management' was rarely used, key elements of self-management support such as goal setting, action planning, and problem solving were core components of therapy rehabilitation interventions. We found high quality evidence that supported self-management in the context of therapy rehabilitation delivered soon after the stroke event resulted in short-term (< 1 year) improvements in basic and extended activities of daily living, and a reduction in poor outcomes (dependence/death). There is some evidence that rehabilitation and problem solving interventions facilitated reintegration into the community.Self-management terminology is rarely used in the context of stroke. However, therapy rehabilitation currently successfully delivers elements of self-management support to stroke survivors and their caregivers with improved outcomes. Future research should focus on managing the emotional, medical and social tasks of long-term survivorship
Mobile phone intervention for increasing adherence to treatment for type 2 diabetes in an urban area of Bangladesh: protocol for a randomized controlled trial
A qualitative exploration of Malaysian cancer patients' perspectives on cancer and its treatment
<p>Abstract</p> <p>Background</p> <p>Cancer patients' knowledge about cancer and experiences with its treatment play an important role in long-term adherence in their disease management. This study aimed to explore cancer patients' knowledge about cancer, their perceptions of conventional therapies and the factors that contribute to medication adherence in the Malaysian population.</p> <p>Methods</p> <p>A qualitative research approach was adopted to gain a better understanding of the current perceptions and knowledge held by cancer patients. Twenty patients were interviewed using a semi-structured interview guide. A saturation point was reached after the 18<sup>th </sup>interview, and no new information emerged with the subsequent 2 interviews. All interviews were transcribed verbatim and analysed by means of a standard content analysis framework.</p> <p>Results</p> <p>The majority of patients related the cause of their cancer to be God's will. Participants perceived conventional therapies as effective due to their scientific methods of preparations. A fear of side effects was main reasons given for delay in seeking treatment; however, perceptions were reported to change after receiving treatment when effective management to reduce the risk of side effects had been experienced.</p> <p>Conclusions</p> <p>This study provides basic information about cancer patients' perceptions towards cancer and its treatment. These findings can help in the design of educational programs to enhance awareness and acceptances of cancer screening. Priorities for future research should focus on patients who refused the conventional therapies at any stage.</p
The Healthy Steps Study: A randomized controlled trial of a pedometer-based Green Prescription for older adults. Trial protocol
Background: Graded health benefits of physical activity have been demonstrated for the reduction of coronary heart disease, some cancers, and type-2 diabetes, and for injury reduction and improvements in mental health. Older adults are particularly at risk of physical inactivity, and would greatly benefit from successful targeted physical activity interventions. Methods/Design: The Healthy Steps study is a 12-month randomized controlled trial comparing the efficacy of a pedometer-based Green Prescription with the conventional time-based Green Prescription in increasing and maintaining physical activity levels in low-active adults over 65 years of age. The Green Prescription interventions involve a primary care physical activity prescription with 3 follow-up telephone counselling sessions delivered by trained physical activity counsellors over 3 months. Those in the pedometer group received a pedometer and counselling based around increasing steps that can be monitored on the pedometer, while those in the standard Green Prescription group received counselling using time-based goals. Baseline, 3 month (end of intervention), and 12 month measures were assessed in face-to-face home visits with outcomes measures being physical activity (Auckland Heart Study Physical Activity Questionnaire), quality of life (SF-36 and EQ-5D), depressive symptoms (Geriatric Depression Scale), blood pressure, weight status, functional status (gait speed, chair stands, and tandem balance test) and falls and adverse events (self-report). Utilisation of health services was assessed for the economic evaluation carried out alongside this trial. As well, a process evaluation of the interventions and an examination of barriers and motives for physical activity in the sample were conducted. The perceptions of primary care physicians in relation to delivering physical activity counselling were also assessed. Discussion: The findings from the Healthy Steps trial are due in late 2009. If successful in improving physical activity in older adults, the pedometer-based Green Prescription could assist in reducing utilisation of health services and improve cardiovascular health and reduction of risk for a range of non-communicable lifestyles diseases
Impact of the introduction of pneumococcal conjugate vaccination on pneumonia in The Gambia: population-based surveillance and case-control studies.
BACKGROUND: Pneumococcal conjugate vaccines (PCVs) are used in many low-income countries but their impact on the incidence of pneumonia is unclear. The Gambia introduced PCV7 in August, 2009, and PCV13 in May, 2011. We aimed to measure the impact of the introduction of these vaccines on pneumonia incidence. METHODS: We did population-based surveillance and case-control studies. The primary endpoint was WHO-defined radiological pneumonia with pulmonary consolidation. Population-based surveillance was for suspected pneumonia in children aged 2-59 months (minimum age 3 months in the case-control study) between May 12, 2008, and Dec 31, 2015. Surveillance for the impact study was limited to the Basse Health and Demographic Surveillance System (BHDSS), whereas surveillance for the case-control study included both the BHDSS and Fuladu West Health and Demographic Surveillance System. Nurses screened all outpatients and inpatients at all health facilities in the surveillance area using standardised criteria for referral to clinicians in Basse and Bansang. These clinicians recorded clinical findings and applied standardised criteria to identify patients with suspected pneumonia. We compared the incidence of pneumonia during the baseline period (May 12, 2008, to May 11, 2010) and the PCV13 period (Jan 1, 2014, to Dec 31, 2015). We also investigated the effectiveness of PCV13 using case-control methods between Sept 12, 2011, and Sept 31, 2014. Controls were aged 90 days or older, and were eligible to have received at least one dose of PCV13; cases had the same eligibility criteria with the addition of having WHO-defined radiological pneumonia. FINDINGS: We investigated 18 833 children with clinical pneumonia and identified 2156 cases of radiological pneumonia. Among children aged 2-11 months, the incidence of radiological pneumonia fell from 21·0 cases per 1000 person-years in the baseline period to 16·2 cases per 1000 person-years (23% decline, 95% CI 7-36) in 2014-15. In the 12-23 month age group, radiological pneumonia decreased from 15·3 to 10·9 cases per 1000 person-years (29% decline, 12-42). In children aged 2-4 years, incidence fell from 5·2 to 4·1 cases per 1000 person-years (22% decline, 1-39). Incidence of all clinical pneumonia increased by 4% (-1 to 8), but hospitalised cases declined by 8% (3-13). Pneumococcal pneumonia declined from 2·9 to 1·2 cases per 1000 person-years (58% decline, 22-77) in children aged 2-11 months and from 2·6 to 0·7 cases per 1000 person-years (75% decline, 47-88) in children aged 12-23 months. Hypoxic pneumonia fell from 13·1 to 5·7 cases per 1000 person-years (57% decline, 42-67) in children aged 2-11 months and from 6·8 to 1·9 cases per 1000 person-years (72% decline, 58-82) in children aged 12-23 months. In the case-control study, the best estimate of the effectiveness of three doses of PCV13 against radiological pneumonia was an adjusted odds ratio of 0·57 (0·30-1·08) in children aged 3-11 months and vaccine effectiveness increased with greater numbers of doses (p=0·026). The analysis in children aged 12 months and older was underpowered because there were few unvaccinated cases and controls. INTERPRETATION: The introduction of PCV in The Gambia was associated with a moderate impact on the incidence of radiological pneumonia, a small reduction in cases of hospitalised pneumonia, and substantial reductions of pneumococcal and hypoxic pneumonia in young children. Low-income countries that introduce PCV13 with reasonable coverage can expect modest reductions in hospitalised cases of pneumonia and a marked impact on the incidence of severe childhood pneumonia. FUNDING: GAVI's Pneumococcal vaccines Accelerated Development and Introduction Plan, Bill & Melinda Gates Foundation, and UK Medical Research Council
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