75 research outputs found
Early Spring Feeding Habits of Bearded Seals (Erignathus Barbatus) in the Central Bering Sea, 1981
The diet of bearded seals, Erignathus barbatus, near St. Matthew Island, Bering Sea, was studied during the early spring of 1981. Eighty-six percent of the 78 seals' stomachs examined contained fish. Other prey taxon groups, in decreasing order of their percentages of occurrence, were crabs (73%), clams (55%), snails (47%), amphipods (32%), shrimp (18%), mysids (13%), marine worms (13%) and cephalopods (4%). The most frequently occurring prey species were capelin, Mallotus villosus, (82%); codfishes, Gadidae (64%); narrow snow crab, Chionoecetes opilio (63%); eelpouts, Lycodes spp. (56%); longsnout prickleback, Lumpenella longirostris (49%); nutshell clams, Nuculana sp. (42%); and moon snails, Polinices sp. (27%). Seventy-seven percent of the seals examined had consumed prey from three or more different taxon groups. We identified seven food items not previously reported as prey of the bearded seal in the Bering Sea. No differences were detected between the diets of males and females and between adults and juveniles, indicating no apparent segregation of foraging by sex or age. Bearded seals in the St. Matthew Island region of the Bering Sea forage in a manner similar to their conspecifics in other areas where fish constitute a major portion of their diet. Prey selection is probably dependent on availability, and diet may be highly diversified even within a relatively small area during a short period of time. Variety in prey consumption exemplified the ability of the bearded seal to forage in the seasonally changing habitat associated with the advance and retreat of the ice front.Key words: bearded seal, Erignathus barbatus, diet, demersal and pelagic fish, benthic invertebrates, prey species diversity On a étudié le régime alimentaire du phoque barbu, Erignathus barbatus, près de l'île Saint Matthew dans la mer de Béring, tôt au printemps de 1981. Quatre-vingt six p. cent des 78 estomacs de phoques examinés contenaient du poisson. Parmi les autres groupes de taxons servant de proies, on retrouvait, par pourcentages décroissants, les crabes (73 p. cent), les myes (55 p. cent), les gastéropodes (47 p. cent), les amphipodes (32 p. cent), les crevettes (18 p. cent), les mysis (13 p. cent), les vers marins (13 p. cent) et les céphalopodes (4 p. cent). Les espèces de proies les plus courantes étaient le capelan, Mallotus villosus (82 p. cent); la morue, Gadidae (64 p. cent); le crabe des neiges, Chionoecetes opilio (63 p. cent); la lotte, sp. Lycodes (56 p. cent); Lumpenella longirostris (49 p. cent); sp. Nuculana (42 p. cent); et la natice, sp. Polinices (27 p. cent). Soixante-dix-sept p. cent des phoques étudiés avaient ingéré des proies venant d'au moins trois différents groupes de taxons. On a identifié sept produits alimentaires qui n'avaient pas encore été reportés comme constituant une proie pour le phoque barbu dans la mer de Béring. On n'a détecté aucune différence entre les régimes alimentaires des mâles et ceux des femelles, ni entre ceux des adultes et ceux des petits, ce qui indique qu'il n'existe apparemment pas de ségrégation quant au sexe ou à l'âge lors du comportement visant la quête de nourriture. Les phoques barbus de la région de l'île Saint Matthew dans la mer de Béring recherchent leur nourriture comme leurs congénères dans d'autres régions où le poisson constitue une grande partie de leur régime. La sélection des proies dépend probablement de leur disponibilité et le régime peut être hautement diversifié, même dans une zone relativement petite et durant une courte période. La variété qui se manifeste dans la consommation des proies montre bien la capacité du phoque barbu à rechercher sa nourriture dans un habitat qui varie selon les saisons et est associé à l'avancée et au retrait du front glaciaire.Mots clés: phoque barbu, Erignathus barbatus, régime alimentaire, poissons démersaux et pélagiques, invertébres benthiques, variété des espèces servant de proi
a report from the Children's Oncology Group and the Utah Population Database
Relatively little is known about the epidemiology and factors underlying
susceptibility to childhood rhabdomyosarcoma (RMS). To better characterize
genetic susceptibility to childhood RMS, we evaluated the role of family
history of cancer using data from the largest case–control study of RMS and
the Utah Population Database (UPDB). RMS cases (n = 322) were obtained from
the Children's Oncology Group (COG). Population-based controls (n = 322) were
pair-matched to cases on race, sex, and age. Conditional logistic regression
was used to evaluate the association between family history of cancer and
childhood RMS. The results were validated using the UPDB, from which 130 RMS
cases were identified and matched to controls (n = 1300) on sex and year of
birth. The results were combined to generate summary odds ratios (ORs) and 95%
confidence intervals (CI). Having a first-degree relative with a cancer
history was more common in RMS cases than controls (ORs = 1.39, 95% CI:
0.97–1.98). Notably, this association was stronger among those with embryonal
RMS (ORs = 2.44, 95% CI: 1.54–3.86). Moreover, having a first-degree relative
who was younger at diagnosis of cancer (<30 years) was associated with a
greater risk of RMS (ORs = 2.37, 95% CI: 1.34–4.18). In the largest analysis
of its kind, we found that most children diagnosed with RMS did not have a
family history of cancer. However, our results indicate an increased risk of
RMS (particularly embryonal RMS) in children who have a first-degree relative
with cancer, and among those whose relatives were diagnosed with cancer at <30
years of age
Short-term effects and long-term changes of FUEL—a digital sports nutrition intervention on REDs related symptoms in female athletes
Female endurance athletes are at high risk for developing Relative Energy Deficiency in Sport (REDs), resulting in symptoms such as menstrual dysfunction and gastrointestinal (GI) problems. The primary aim of this study was to investigate effects of the FUEL (Food and nUtrition for Endurance athletes—a Learning program) intervention consisting of weekly online lectures combined with individual athlete-centered nutrition counseling every other week for sixteen weeks on REDs related symptoms in female endurance athletes at risk of low energy availability [Low Energy Availability in Females Questionnaire (LEAF-Q) score ≥8]. Female endurance athletes from Norway (n = 60), Sweden (n = 84), Ireland (n = 17), and Germany (n = 47) were recruited. Fifty athletes with risk of REDs (LEAF-Q score ≥8) and with low risk of eating disorders [Eating Disorder Examination Questionnaire (EDE-Q) global score <2.5], with no use of hormonal contraceptives and no chronic diseases, were allocated to either the FUEL intervention (n = 32) (FUEL) or a sixteen-week control period (n = 18) (CON). All but one completed FUEL and n = 15 completed CON. While no evidence for difference in change in LEAF-Q total or subscale scores between groups was detected post-intervention (BFincl < 1), the 6- and 12-months follow-up revealed strong evidence for improved LEAF-Q total (BFincl = 123) and menstrual score (BFincl = 840) and weak evidence for improved GI-score (BFincl = 2.3) among FUEL athletes. In addition, differences in change between groups was found for EDE-Q global score post-intervention (BFincl = 1.9). The reduction in EDE-Q score remained at 6- and 12- months follow-up among FUEL athletes. Therefore, the FUEL intervention may improve REDs related symptoms in female endurance athletes.Clinical Trial Registrationwww.clinicaltrials.gov (NCT04959565)
MODEL PENGELOLAAN PASCA TANGKAP SEBAGAI UPAYA PENGENTASAN KEMISKINAN MASYARAKAT KAMPUNG NELAYAN DI PULAU ENGGANO
Relatively little is known about the epidemiology and factors underlying susceptibility to childhood rhabdomyosarcoma (RMS). To better characterize genetic susceptibility to childhood RMS, we evaluated the role of family history of cancer using data from the largest case-control study of RMS and the Utah Population Database (UPDB). RMS cases (n=322) were obtained from the Children's Oncology Group (COG). Population-based controls (n=322) were pair-matched to cases on race, sex, and age. Conditional logistic regression was used to evaluate the association between family history of cancer and childhood RMS. The results were validated using the UPDB, from which 130 RMS cases were identified and matched to controls (n=1300) on sex and year of birth. The results were combined to generate summary odds ratios (ORs) and 95% confidence intervals (CI). Having a first-degree relative with a cancer history was more common in RMS cases than controls (ORs=1.39, 95% CI: 0.97-1.98). Notably, this association was stronger among those with embryonal RMS (ORs=2.44, 95% CI: 1.54-3.86). Moreover, having a first-degree relative who was younger at diagnosis of cancer (<30years) was associated with a greater risk of RMS (ORs=2.37, 95% CI: 1.34-4.18). In the largest analysis of its kind, we found that most children diagnosed with RMS did not have a family history of cancer. However, our results indicate an increased risk of RMS (particularly embryonal RMS) in children who have a first-degree relative with cancer, and among those whose relatives were diagnosed with cancer at <30years of age
Targeted Sequencing in Chromosome 17q Linkage Region Identifies Familial Glioma Candidates in the Gliogene Consortium
Glioma is a rare, but highly fatal, cancer that accounts for the majority of malignant primary brain tumors. Inherited predisposition to glioma has been consistently observed within non-syndromic families. Our previous studies, which involved non-parametric and parametric linkage analyses, both yielded significant linkage peaks on chromosome 17q. Here, we use data from next generation and Sanger sequencing to identify familial glioma candidate genes and variants on chromosome 17q for further investigation. We applied a filtering schema to narrow the original list of 4830 annotated variants down to 21 very rare (,0.1% frequency), non-synonymous variants. Our findings implicate the MYO19 and KIF18B genes and rare variants in SPAG9 and RUNDC1 as candidates worthy of further investigation. Burden testing and functional studies are planned
Cyclical changes in seroprevalence of leptospirosis in California sea lions: endemic and epidemic disease in one host species?
BackgroundLeptospirosis is a zoonotic disease infecting a broad range of mammalian hosts, and is re-emerging globally. California sea lions (Zalophus californianus) have experienced recurrent outbreaks of leptospirosis since 1970, but it is unknown whether the pathogen persists in the sea lion population or is introduced repeatedly from external reservoirs.MethodsWe analyzed serum samples collected over an 11-year period from 1344 California sea lions that stranded alive on the California coast, using the microscopic agglutination test (MAT) for antibodies to Leptospira interrogans serovar Pomona. We evaluated seroprevalence among yearlings as a measure of incidence in the population, and characterized antibody persistence times based on temporal changes in the distribution of titer scores. We conducted multinomial logistic regression to determine individual risk factors for seropositivity with high and low titers.ResultsThe serosurvey revealed cyclical patterns in seroprevalence to L. interrogans serovar Pomona, with 4-5 year periodicity and peak seroprevalence above 50%. Seroprevalence in yearling sea lions was an accurate index of exposure among all age classses, and indicated on-going exposure to leptospires in non-outbreak years. Analysis of titer decay rates showed that some individuals probably maintain high titers for more than a year following exposure.ConclusionThis study presents results of an unprecedented long-term serosurveillance program in marine mammals. Our results suggest that leptospirosis is endemic in California sea lions, but also causes periodic epidemics of acute disease. The findings call into question the classical dichotomy between maintenance hosts of leptospirosis, which experience chronic but largely asymptomatic infections, and accidental hosts, which suffer acute illness or death as a result of disease spillover from reservoir species
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk
BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk-modifying loci, we performed a multi-stage GWAS of 11,705 BRCA1 carriers (of whom 5,920 were diagnosed with breast and 1,839 were diagnosed with ovarian cancer), with a further replication in an additional sample of 2,646 BRCA1 carriers. We identified a novel breast cancer risk modifier locus at 1q32 for BRCA1 carriers (rs2290854, P = 2.7×10-8, HR = 1.14, 95% CI: 1.09-1.20). In addition, we identified two novel ovarian cancer risk modifier loci: 17q21.31 (rs17631303, P = 1.4×10-8, HR = 1.27, 95% CI: 1.17-1.38) and 4q32.3 (rs4691139, P = 3.4×10-8, HR = 1.20, 95% CI: 1.17-1.38). The 4q32.3 locus was not associated with ovarian cancer risk in the general population or BRCA2 carriers, suggesting a BRCA1-specific associat
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State of the California Current 2014-15: Impacts of the Warm-Water "Blob"
In 2014, the California Current (~28˚–48˚N) saw average, or below average, coastal upwelling and relatively low productivity in most locations, except from 38˚–43˚N during June and July. Chlorophyll-a levels were low throughout spring and summer at most locations, except in a small region around 39˚N. Catches of juvenile rockfish (an indicator of upwelling-related fish species) remained high throughout the area surveyed (32˚–43˚N). In the fall of 2014, as upwelling ceased, many locations saw an unprecedented increase in sea surface temperatures (anomalies as large as 4˚C), particularly at 45˚N due to the coastal intrusion of an extremely anomalous pool of warm water. This warm surface anomaly had been building offshore in the Gulf of Alaska since the fall of 2013, and has been referred to as the “blob.” Values of the Pacific Decadal Oscillation index (PDO) continued to climb during 2014, indicative of the increase in warm coastal surface waters, whereas the North Pacific Gyre Oscillation index (NPGO) saw a slight rebound to more neutral values (indicative of average productivity levels) during 2014. During spring 2015, the upwelling index was slightly higher than average for locations in the central and northern region, but remained below average at latitudes south of 35˚N. Chlorophyll a levels were slightly higher than average in ~0.5˚ latitude patches north of 35˚N, whereas productivity and phytoplankton biomass were low south of Pt. Conception. Catches of rockfish remained high along most of the coast, however, market squid remained high only within the central coast (36˚–38˚N), and euphausiid abundance decreased everywhere, as compared to the previous year. Sardine and anchovy were nearly absent from the southern portion of the California Current system (CCS), whereas their larvae were found off the coast of Oregon and Washington during winter for the first time in many years. Waters warmed dramatically in the southern California region due to a change in wind patterns similar to that giving rise to the blob in the broader northeast Pacific. For most of the coast, there were intrusions of species never found before or found at much higher abundances than usual, including fish, crustaceans, tunicates and other gelatinous zooplankton, along with other species often indicative of an El Niño. Thus species richness was high in many areas given the close juxtaposition of coastal upwelling-related species with the offshore warm-water intrusive or El Niño-typical taxa. Thus the California Current by 2015 appears to have transitioned to a very different state than previous observations
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State of the California Current 2013-14: El Niño Looming
In 2013, the California current was dominated by
strong coastal upwelling and high productivity. Indices
of total cumulative upwelling for particular coastal
locations reached some of the highest values on record.
Chlorophyll a levels were high throughout spring and
summer. Catches of upwelling-related fish species were
also high. After a moderate drop in upwelling during fall
2013, the California current system underwent a major
change in phase. Three major basin-scale indicators, the
PDO, the NPGO, and the ENSO-MEI, all changed
phase at some point during the winter of 2013/14. The
PDO changed to positive values, indicative of warmer
waters in the North Pacific; the NPGO to negative values,
indicative of lower productivity along the coast; and
the MEI to positive values, indicative of an oncoming
El Niño. Whereas the majority of the California Current
system appears to have transitioned to an El Niño
state by August 2014, based on decreases in upwelling
and chlorophyll a concentration, and increases in SST,
there still remained pockets of moderate upwelling,
cold water, and high chlorophyll a biomass at various central
coast locations, unlike patterns seen during the
more major El Niños (e.g., the 97–98 event). Catches of
rockfish, market squid, euphausiids, and juvenile sanddab
remained high along the central coast, whereas catches
of sardine and anchovy were low throughout the CCS.
2014 appears to be heading towards a moderate El Niño
state, with some remaining patchy regions of upwelling-driven
productivity along the coast. Superimposed on
this pattern, three major regions have experienced possibly
non-El Niño-related warming since winter: the
Bering Sea, the Gulf of Alaska, and offshore of southern
California. It is unclear how this warming may interact
with the predicted El Niño, but the result will likely be
reduced growth or reproduction for many key fisheries
species
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State of the California Current 2012–13: No Such Thing as an "Average" Year
This report reviews the state of the California Current System (CCS) between winter 2012 and spring 2013, and includes observations from Washington State to Baja California. During 2012, large-scale climate modes indicated the CCS remained in a cool, productive phase present since 2007. The upwelling season was delayed north of 42˚N, but regions to the south, especially 33˚ to 36˚N, experienced average to above average upwelling that persisted throughout the summer. Contrary to the indication of high production suggested by the climate indices, chlorophyll observed from surveys
and remote sensing was below average along much of
the coast. As well, some members of the forage assemblages
along the coast experienced low abundances in
2012 surveys. Specifically, the concentrations of all lifestages
observed directly or from egg densities of Pacific
sardine, Sardinops sagax, and northern anchovy, Engraulis
mordax, were less than previous years’ survey estimates.
However, 2013 surveys and observations indicate an
increase in abundance of northern anchovy. During winter
2011/2012, the increased presence of northern copepod
species off northern California was consistent with
stronger southward transport. Krill and small-fraction
zooplankton abundances, where examined, were generally
above average. North of 42˚N, salps returned to
typical abundances in 2012 after greater observed concentrations
in 2010 and 2011. In contrast, salp abundance
off central and southern California increased after a
period of southward transport during winter 2011/2012.
Reproductive success of piscivorous Brandt’s cormorant,
Phalacrocorax penicillatus, was reduced while planktivorous
Cassin’s auklet, Ptychoramphus aleuticus was elevated.
Differences between the productivity of these two seabirds
may be related to the available forage assemblage observed in the surveys. California sea lion pups from
San Miguel Island were undernourished resulting in a
pup mortality event perhaps in response to changes in
forage availability. Limited biological data were available
for spring 2013, but strong winter upwelling coastwide
indicated an early spring transition, with the strong
upwelling persisting into early summer
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