CURCUMIN PROTECTION AGAINST CADMIUM-INDUCED OXIDATIVE STRESS IN PANCREAS OF SWISS ALBINO MICE

Objective: This study was planned to explore the protective efficacy of Curcuma longa (curcumin) against cadmium chloride (CdCl2)-induced oxidative stress in pancreatic tissue of albino mice.Methods: A total of 40 albino mice were equally divided into eight groups (five mice for each). The mice were kept on standard feed and water ad libitum. Control Groups 1 and 5 mice were given equal amount of distilled water, Groups 2 and 6 mice received 1 mg/kg body weight of CdCl2 on alternate days, and Group 3 and 7 received 1 mg/kg body weight of CdCl2 on alternate days and 100 mg/kg body weight of curcumin every day. Groups 4 and 8 received 100 mg/kg body weight of curcumin daily and were kept as positive control. Autopsies were done on 15 and 45 days post-treatment. The pancreas was collected from each mouse and homogenized for biochemical study.Results: The results of the present study revealed that Cd-induced oxidative stress depleted the antioxidant scavenger system and curcumin showed free radical scavenging potential. The activities of antioxidant enzymes, i.e., superoxide dismutase, catalase, glutathione peroxidase were observed to be significantly decreased, and methylenedioxyamphetamine concentration was increased in CdCl2-treated group which was restored to normal level after curcumin treatment.Conclusion: It can be concluded that curcumin acts as a powerful and beneficial antioxidant against oxidative stress by scavenging the free radicals produced by CdCl2

Role of ICT in the Process of Teaching and Learning

ICT enables self-paced learning through various tools such as assignment, computer etc as a result of this the teaching learning enterprise has become more productive and meaningful. ICT helps facilitate the transaction between producers and users by keeping the students updated and enhancing teachers capacity and ability fostering a live contact between the teacher and the student through e-mail, chalk session, e-learning, web-based learning including internet, intranet, extranet, CD-ROM, TV audio-videotape. Edusat technology has become very powerful media for interactive participation of experts and learners and it reaches the unreachable. Emerging learning Technology (ELT) of bogging, Integrated Learning  Modules, a pod cast, Wikis, Enhancement of Browsers, e-learning, M-learning, U-learning have started making rapid strides in teaching learning processes. Keywords: Web Browsers, Technology enhanced learning, Self paced learning, Instructional software, Interactive learning, Integrated Learning Module, U- learning. E-learning ,M-learning

Spontaneous heterotopic pregnancy: a case report

Heterotopic pregnancy is defined as multiple gestation in which intrauterine and extrauterine gestational sacs co-exist. The extra uterine gestational sac is most commonly tubal ectopic pregnancy. We presented case of a 26 years old multigravida who presented to emergency with complaints of pain abdomen and giddiness for 2-3 days. She was at period of gestation (POG) 7 weeks and on clinical examination patient was anxious with mild pallor, mildly tachycardiac and blood pressure (BP) was 90/60 mm of Hg. After thorough clinical examination and sonography diagnosis of heterotopic pregnancy with ruptured tubal ectopic was made. She was taken up for Emergency laparotomy after investigations and consent. Left salpingectomy was done and she was discharged with a single intrauterine live pregnancy on 6th post op day. For early detection of cases of heterotopic pregnancy careful evaluation of adnexa is mandatory in early gestation scan

The Occupational Stress Women Teachers Towards Joint and Nuclear Society

Work is a central part of human life. It is the expression of the basic need to accomplish, to create, to feel satisfaction, and to feel meaningful. The rapidly changing nature of work has resulted in new and far-reaching mechanisms for management control in the form of monitoring, layoffs, and change in work rules, all of which contribute to increased levels of occupational stress. Although office work has always been stressful, several scientific studies and surveys have helped focus attention on the issue of job stress. Among the major negative effects of the job, stress is its impact on a person's self-image and self-esteem, which in turn, affects one's relationship with family, friends, and co-workers. The problems last far longer than the time we spend at work and are not easily left behind at the end of the day

Testing the Psychometric Properties of the Modeling Self-Efficacy Scale

The Modeling Self-Efficacy Scale was developed to measure middle and high school students’ confidence in understanding and solving modeling tasks. The scale was administered to 225 eighth- and ninth-grade students. Participants read modeling tasks adapted from Programme for International Student Assessment’s 2003 problem-solving assessment and rated their confidence on a 100-point self-efficacy scale. Confirmatory factor analysis indicated that modeling self-efficacy is a unidimensional construct, best elicited by a repeated-measures-style survey design in which participants responded to the same self-efficacy items across multiple modeling problems. The omega reliability coefficient for the scale was .88. The findings suggest that the Modeling Self-Efficacy Scale is a reliable and valid instrument for middle and high school mathematics students

Estudio del efecto moderador en una localidad encuestada sobre la intención de adopción de M-Commerce

Introduction: The present research was conducted at the University of Delhi in 2018. Problem: With the increase in usage of internet technology through wireless devices, the relevance of m-commerce has amplified. In a developing country like India, the rural and urban population is not equally divided on the use of m-commerce and this demands a detailed study regarding this problem.  Objective: The study aims to determine the factors that influence the m-commerce adoption intention of customers and how the effect varies over rural and urban populations. Methodology: This study combines the TAM and UTAUT model to consider the determinants as perceived ease of use, perceived usefulness, perceived risk, perceived cost, social interaction, and facilitating conditions, taking the endogenous variable as intention to adopt m-commerce.     Results: The results of PLS-SEM accepted the hypotheses underlying the model and also validated the moderating role played by a respondent’s locality over the intention to adopt m-commerce. Conclusion: The proposed model was validated by using PLS-SEM approach on a sample size of 200 collected from the urban and rural areas of Delhi NCR. Moreover, the moderating effect of a respondent’s locality was observed over adoption intention. Originality: With the advancement in technological infrastructure and improvement in mobile data facilities, customers have shown enthusiasm towards making online transactions using their phones. The advantage of mobile commerce over computer based electronic commerce is its mobility. Extant research has shown interest in studying the adoption intention of mobile commerce, based on determinants from the TAM or UTAUT model or their combinations. This study combines both models to choose the determinants of mobile adoption intention.  Limitation: Further studies can be conducted by considering other combinations of determinants and extending the model to incorporate the loyalty measures.Introducción: la presente investigación se realizó en la Universidad de Delhi en 2018. Problema: con el aumento en el uso de la tecnología de Internet a través de dispositivos inalámbricos, larelevancia del comercio móvil se ha ampliado. En un país en desarrollo como India, la población rural y urbana no está dividida por igual en el uso del comercio móvil y esto exige un estudio detallado sobre este problema. Objetivo: el estudio tiene como objetivo determinar los factores que influyen en la intención de adopción deM-Commerce de los clientes y cómo varía el efecto sobre las poblaciones rurales y urbanas.Metodología: este estudio combina el modelo TAM y UTAUT para considerar los determinantes como facilidad de uso percibida, utilidad percibida, riesgo percibido, costo percibido, interacción social y condiciones facilitadoras, tomando la variable endógena como intención de adoptar el comercio móvil. Resultados: los resultados de PLS-SEM aceptaron las hipótesis subyacentes al modelo y también validaronel papel moderador desempeñado por la localidad del encuestado sobre la intención de adoptar el comerciomóvil. Conclusión: el modelo propuesto fue validado utilizando el enfoque PLS-SEM en un tamaño de 200 muestras recolectadas de las áreas urbanas y rurales de Delhi NCR. Además, el efecto moderador de la localidad del encuestado se observó sobre la intención de adopción. Originalidad: con el avance en la infraestructura tecnológica y la mejora en las instalaciones de datos móviles, los clientes han mostrado entusiasmo por realizar transacciones en línea usando sus teléfonos. La ventaja del comercio móvil sobre el comercio electrónico basado en computadora es su movilidad. La investigación existente ha mostrado interés en estudiar la intención de adopción del comercio móvil, basada en determinantes de la intención de adopción móvil

Evaluation of hybrid problem-based learning in large classrooms: a qualitative and quantitative analysis

Background: Problem Based Learning (PBL) for teaching preclinical sciences has been proposed in curricular reform by Medical Council of India. PBL is a student-centred approach, enabling deep and transformative student learning. A 'hybrid' approach to PBL uses a range of class-based teaching methods; delivering a mode of PBL which is less resource intensive and more flexible than ‘pure’ PBL. In hybrid PBL, problems are solved in groups, but lectures are used to present the fundamental concepts and difficult topics. Our institution follows a traditional lecture-based curriculum. The present cohort study was undertaken to determine student and faculty perceptions for hybrid PBL as well as impact on student engagement.Methods: Hybrid PBL method was implemented for one cohort of hundred first year medical students. Previous batch was used as control taught by traditional lecture-based curriculum alone. Methodological triangulation design was employed for impact of hybrid PBL on student engagement (attendance scores-Chi square) and student and faculty perception to hybrid PBL (reflections- grounded theory)Results: The mean attendance score of MBBS batch 2016 was significantly better than batch 2015 (p=0.0001). The emerging themes in student reflections were innovative method, collaborative learning, quest for knowledge, promote long term retention and links to real-life scenario. Acquisition of soft skills (social and moral responsibility) was novel emerging theme in student reflections. Active student participation and improved critical thinking were themes expressed in faculty perceptions.Conclusions: Hybrid PBL with small groups is successful in large classrooms. Introduced at the initial phase of undergraduate medical education, it can assist robust self-appraisal in students and strengthen soft skills

Scanning Electron Microscopy study of root tissue of muskmelon: Transferring Fusarium wilt resistance from snapmelon to muskmelon

The overall aim of this study was to investigate the level of Fusarium oxysporum f. sp. Melonis (F.o.m.) infection by studying the Scanning electron micrographs of transverse sections of parent inbred lines and developed F1 hybrid. The current study involved KP4HM-15 (Fusarium wilt resistant inbred line) in a crossing program with well adapted muskmelon cv. Punjab Sunehri (PS) to develop FW resistant hybrid possessing high yield and quality traits. Fom infects melon root and trails through the cortical and endodermal cells to reach xylem vessels by penetrating through pits. This is the first SEM appraisal of the whole tap root of field grown melon accessions, KP4HM-15, PS and PSxKP4HM-15 (MH-41) (F1 hybrid) aimed to discern the role of the root morphometric characters for imparting FW resistance. The trend for root epidermo-cortical thickness was KP4HM-15>PS>MH-41 while for the xylem diameter was MH-41> KP4HM-15>PS. The F1 hybrid exhibited FW resistance intermediate among the two parents i.e. absence or presence of less mycelia as compared to the susceptible parent (PS). However, the extent of infection was higher than the resistant parent KP4HM-15, which shows that partial resistance was transferred from KP4HM-15 to MH-41. This study accentuates the resistance gene mining and use of wild melon accessions to introgress FW resistance in commercial melon cultivars

Primary ovarian ectopic pregnancy: an unusual case study

Ovarian pregnancy is rare variant of ectopic pregnancy. An accurate preoperative diagnosis is very challenging various advances in diagnostic modalities like Transvaginal ultrasonography has evolved in identifying an ovarian pregnancy. It results in significant maternal morbidity, fetal loss, repeat ectopic, impairment of subsequent fertility. The case report a 34-year female who presented with pain and severe anemia and explored keeping in view ruptured tubal ectopic but intraoperatively diagnosed as primary ovarian pregnancy and managed conservatively by ovarian wedge resection