Integration of fuzzy reasoning approach (FRA) and fuzzy analytic hierarchy process (FAHP) for risk assessment in mining industry

Purpose: Mining industry has always been known for its unsafe working environment. This industry is one of the most hazard prone industries. To maintain safety in workplace timely assessment of risk associated with different operations performed to extract ore from the ore body has become necessity. To serve the said purpose, present work demonstrates a robust hybrid risk assessment approach for mining industry. Design/Methodology: Accident data from 1995 to 2012 is reviewed to identify hazards contributed to negative outcomes. The FRA approach is implemented to evaluate the risk levels associated with identified hazard factors. Thereafter AHP pairwise comparison matrix is developed to obtain priority weights for the hazard factors. Final priority of hazards based on severity of level of risk associated with them is obtained considering the outcome of FRA approach in terms of risk score for the hazards, combined with the priority weights obtained from AHP technique. Findings: Defuzzified FAHP weight of hazard factors, this weight gives priority sequence of hazards to be considered for development of plan of mitigation. Originality/Value: Risk assessment is a requirement of the Occupational Health and Safety Act 2000 (Section 7 & 8). The data required to assess the risk is uncertain, and in such case fuzzy approach is well suited to process the data and get the crisp output. The output of fuzzy approach is made robust with its integration to AHP. In this way FAHP can be used as robust technique for risk assessment in this industry and this technique develops an efficient safety management system for the achievement of goal to develop the workplace with zero accident, which many other countries have already achieved.Peer Reviewe

GROWTH OF OPEN ACCESS SCHOLARLY COMMUNICATION IN BRICS COUNTRIES

This paper aims to investigate the present status of open access (OA) scholarly communication from Brazil, Russia, India, China and South Africa (BRICS) countries from 2011 to 2020 and compare their performance in terms of scholarly communication. Articles contributed by the scholars of BRICS countries, the data collected from Scopus database. The retrieved results are limited to the “all open access, Publisher full Gold OA, Publisher Hybrid Gold OA, Publisher Free to read Bronze OA and repository Green OA”, “articles” published in the “English language” from 2011 to 2020. Total 13,943,979 papers published from BRICS countries, out of which 1578902 articles published in Open Access sources. Brazil has published the highest number of OA publications (21%) regarding its total Publications. China has the highest contribution (65%) in OA publications in comparison to other BRICS countries. Although, there has been a constant growth in OA publications in BRICS countries from 66,481 in 2011 to 280,150 in 2020. China has the highest publications in all open access models. Brazil, India and South Africa have contributed more OA publications in Medicine discipline than other disciplines. The PLOS One open access scientific journal is at the top with 43,532 OA publications from Brazil, China and South Africa. This paper also includes the ranking of institutions of BRICS countries based on their OA publications from 2016 to 2019, i.e. CWTS Leiden Ranking 2021. The study is limited to BRICS countries and may increase the awareness of OA publications from BRICS countries

1960−1980-luvun omakotitalojen rakennusvirheet ja niiden korjaus

Tämän insinöörityön esimerkkikohteena on käytetty Kajaanissa sijaitsevaa omakotitaloa, joka on rakennettu 1960-luvulla ja myöhemmin laajennettu 1980-luvulla. Vuonna 2012 - 2013 taloon rakennettiin uusi laajennus, jonka yhteydessä 1960- ja 1980-luvulla tehdyt osat rakennuksesta muutettiin vastaamaan nykypäivän tasoa kaikilta osin. Rakennuksen lämmöneristeet uusittiin osittain, ja samalla seinät ja yläpohja lisälämmöneristettiin. Samassa yhteydessä seiniin ja yläpohjiin vaihdettiin nykyaikainen höyrynsulku ilmansulkupaperin tilalle. Lattiarakenteet muutettiin 1960-luvulla tehdyn talon osalta ilmastoiduksi lattiaksi. Lattiarakenteet ovat osittain puukoolattuja lat-tioita ja osittain kaksoislaatallisia lattioita. Rakennus nykyaikaistettiin myös ilmanvaihdon ja sähköistyksen osalta. Remontin lopputuloksena saatiin lähes kaikilta osin nykyaikainen omakotitalo teknisesti ja ulkonäöllisesti. Insinöörityössä käydään läpi tyypillisimmät rakennusvirheet ja niiden korjaaminen 1960−1980-luvun omakotita-loissa sekä omakotitalojen eri rakenneosat ja niissä mahdollisesti olevat ongelmat kyseiseltä aikaväliltä, kuten pe-rustusrakenteiden kosteusvaurioiden ja vesikattorakenteiden korjaaminen. Perustusrakenteiden suurimpana on-gelman aiheuttajana ovat maaperästä kapillaarisesti nouseva kosteus, ja vesikatteiden tyypillisiä ongelmia ovat puutteelliset läpiviennit, pinnoitevauriot ja vesikatteen teknisen käyttöiän päättyminen. Puutteellinen höyrynsulku ja vähäinen lämmöneriste voivat aiheuttaa kosteus- ja mikrobivaurioita yläpohjassa rakennuksen sisältä vuotavan lämmön ja kosteuden takia. Tämän insinöörityön tarkoituksena on selvittää rakennusosien tyypillisimmät ongelmat sekä toimia oppaana ky-seisen ajanjakson omakotitaloja remontoivalle ja niille, jotka harkitsevat omakotitalon ostoa. Tässä työssä tulee ilmi yleisimmät riskirakenteet, joihin kannattaa kiinnittää erityistä huomiota taloa remontoitaessa tai sitä ostaessa. Työstä on tehty kattava kokonaisuus, jota voidaan hyödyntää remontointiin ryhtyessä. Työstä voi saada vihjeitä tyypillisistä vaurioista, jotka kannattaa tutkia ja korjata remontin yhteydessä.The basis for this thesis is a detached house located in Kajaani built in the 1960s and extended in the 1980s. In the years 2012 and 2013 the building was extended and at the same time the old part of the building was reno-vated totally to meet today`s specifications. The building was completely demolished inside and rebuilt. The thermal insulation, roof and façade were renovated and the floor structures fixed. This work includes information about typical construction defects in the 1960 – 1980s and gives instructions on how to repair them. The biggest cause of damage is ground moisture and defective rooftop. Defective thermal insulation and steam lock can cause moisture and mold problems in the roof. The objective of this thesis work is to survey different structural defects and give instructions for house renova-tion. The most typical structural risks are paid special attention to. This work is a comprehensive guide book for persons who are thinking of renovating or buying a house built in the 1960s– 1980s

Regulation of wound strength by Ocimum sanctum: in silico and in vivo evidences

Background: The present work has been an attempt to facilitate the scientific understanding of the wound strength by Ocimum sanctum (OS, holy basil) a traditional knowledge practiced since ancient times in India.Methods: The in vivo Incision (wound strength) and Dead space wound models (biochemical estimation of components of ECM) in rats and  In silico method, where one of the target proteins from each class of MMPs involved in wound strength was selected for molecular docking with eugenol (one of the flavonoid present in OS).Results: Molecular docking showed that eugenol was able to inhibit all selected MMPs, i.e. collagenase (-6.37 Kcal/mol), gelatinase (-5.99 Kcal/mol), elastase (-6.31 Kcal/mol) and stromelysin (-5.79 Kcal/mol). Ethanolic extract of Ocimum sanctum (OSE, 200-800 mg/kg) when administered as suspension showed dose-dependent increase in wound breaking strength in in vivo Incision wound rat model. OSE 400 mg/kg produced a significant increase in protein and collagen constituents like hydroxyproline, hexuronic acid and hexosamine in the connective tissue content of extracellular matrix when studied in Dead space wound model in rat.Conclusions: The present study is an attempt to correlate the in vivo findings on wound strength promoting activity by Ocimum sanctum with in silico tools

Context-NER : Contextual Phrase Generation at Scale

NLP research has been focused on NER extraction and how to efficiently extract them from a sentence. However, generating relevant context of entities from a sentence has remained under-explored. In this work we introduce the task Context-NER in which relevant context of an entity has to be generated. The extracted context may not be found exactly as a substring in the sentence. We also introduce the EDGAR10-Q dataset for the same, which is a corpus of 1,500 publicly traded companies. It is a manually created complex corpus and one of the largest in terms of number of sentences and entities (1 M and 2.8 M). We introduce a baseline approach that leverages phrase generation algorithms and uses the pre-trained BERT model to get 33% ROUGE-L score. We also do a one shot evaluation with GPT-3 and get 39% score, signifying the hardness and future scope of this task. We hope that addition of this dataset and our study will pave the way for further research in this domain.Comment: 12 pages, 2 Figures, 1 Algorithm, 8 Tables. Accepted in NeurIPS 2022 - Efficient Natural Language and Speech Processing (ENLSP) Worksho

A Blank Optimization by Effective Reverse Engineering and Metal Forming Analysis

143-148Finite element methods allow us to better understand the complex plastic deformation behaviour of a sheet metal component during forming. The purpose of the present work is to optimise the current 1535 × 1600 × 1.2 mm blank sheet of a commercial vehicle engine tunnel bottom using finite element simulation without violating safety and efficiency. The goal of this communication is to look at methods of finite element simulation that are used to solve the related problem. For generating the CAD data of the forming tools, a reverse engineering technique has been adopted. The formation simulation is performed using the commercially available PAMSTAMP explicit solver-based program. The blank holder force was increased by around 15 % (from the current force of 350 kN to 400 kN) while measuring the reduced blank width. The optimised blank sheet's simulation results have been compared to the current blank, ensuring that the optimised blank is appropriate for the bottom portion of the engine tunnel without any defects or failures being produced. In the application of sheet metal formation, finite element techniques have always enabled us in weight savings and cost-saving of automotive components

Open Access Extracts from Acacia catechu suppress HIV-1 replication by inhibiting the activities of the viral

Background: Acacia catechu (Mimosa family) stem bark extracts have been used traditionally as a dietary supplement as well as a folk medicine given its reported anti-inflammatory, immunomodulatory, hepatoprotective, antioxidant, anti-microbial and anti-tumor activities. The present study was undertaken to evaluate the anti-HIV-1 activity of the extracts from stem bark of A. catechu. Methods: The aqueous and 50 % ethanolic extracts of A. catechu stem bark were prepared and 50 % ethanolic extract was further fractioned by successively partitioning with petroleum ether, chloroform and n-butanol. All the extracts and fractions were evaluated for cytotoxicity and anti-HIV-1 activity using different in vitro assays. The active n-butanol fraction was evaluated for its inhibition against HIV-1 reverse transcriptase, integrase, protease, pro-viral genome integration and viral Tat protein mediated transactivation. The effect of n-butanol fraction on the induction of pro-inflammatory cytokines secretion in Vk2/E6E7 cells and transepithelial resistance in Caco-2 and HEC-1A cells was investigated. Results: The aqueous and 50 % ethanolic extracts of A. catechu showed IC50 values of 1.8 ± 0.18 μg/ml and 3.6 ± 0.31 μg/ml, respectively in cell-free virus based assay using TZM-bl cells and HIV-1NL4.3 (X-4 tropic). In the above assay, n-butanol fraction exhibited anti-HIV-1 activity with an IC50 of 1.7 ± 0.12 μg/ml. The n-butanol fractio

Cutaneous neurofibromas Current clinical and pathologic issues

ObjectiveTo present the current terminology and natural history of neurofibromatosis 1 (NF1) cutaneous neurofibromas (cNF).MethodsNF1 experts from various research and clinical backgrounds reviewed the terms currently in use for cNF as well as the clinical, histologic, and radiographic features of these tumors using published and unpublished data.ResultsNeurofibromas develop within nerves, soft tissue, and skin. The primary distinction between cNF and other neurofibromas is that cNF are limited to the skin whereas other neurofibromas may involve the skin, but are not limited to the skin. There are important cellular, molecular, histologic, and clinical features of cNF. Each of these factors is discussed in consideration of a clinicopathologic framework for cNF.ConclusionThe development of effective therapies for cNF requires formulation of diagnostic criteria that encompass the clinical and histologic features of these tumors. However, there are several areas of overlap between cNF and other neurofibromas that make distinctions between cutaneous and other neurofibromas more difficult, requiring careful deliberation with input across the multiple disciplines that encounter these tumors and ultimately, prospective validation. The ultimate goal of this work is to facilitate accurate diagnosis and meaningful therapeutics for cNF

The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis

Background: The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platform titled "International Natural Product Sciences Taskforce" (INPST) was established in 2018, to bring together in collaborative environment individuals and organizations interested in natural product scientific research, and to empower their interactions by using digital communication tools. Methods: In this work, we present a general overview of INPST activities and showcase the specific use of Twitter as a powerful networking tool that was used to host a one-week "2021 INPST Twitter Networking Event" (spanning from 31st May 2021 to 6th June 2021) based on the application of the Twitter hashtag #INPST. Results and Conclusion: The use of this hashtag during the networking event period was analyzed with Symplur Signals (https://www.symplur.com/), revealing a total of 6,036 tweets, shared by 686 users, which generated a total of 65,004,773 impressions (views of the respective tweets). This networking event's achieved high visibility and participation rate showcases a convincing example of how this social media platform can be used as a highly effective tool to host virtual Twitter-based international biomedical research events