Analysis of volatile compounds of Malaysian Tualang (Koompassia excelsa) honey using gas chromatography mass spectrometry

The constituents of honey’s volatile compounds depend on the nectar source and differ depending on the place of origin. To date, the volatile constituents of Tualang honey have never been investigated. The objective of this study was to analyze the volatile compounds in local Malaysian Tualang honey. A continuous extraction of Tualang honey using five organic solvents was carried out starting from non-polar to polar solvents and the extracted samples were analysed using gas chromatography-massspectrometry (GC-MS). Overall, 35 volatile compounds were detected. Hydrocarbons constitute 58.5% of the composition of Tualang honey. Other classes of chemical compounds detected included acids, aldehydes, alcohols, ketones, terpenes, furans and a miscellaneous group. Methanol yielded the highest number of extracted compounds such as acids and 5-(Hydroxymethyl) furfural (HMF). This is the first study to describe the volatile compounds in Tualang honey. The use of a simple one tube, stepwise, non-thermal liquid-liquid extraction of honey is a advantageous as it prevents sample loss. Further research to test the clinical benefits of these volatile compounds is recommended

Partial Oxidation of Surrogate Jet-A Fuel Over SiO\u3csub\u3e2\u3c/sub\u3e Supported MoO\u3csub\u3e2\u3c/sub\u3e

A SiO2-supported MoO2 nanoparticle catalyst was synthesized by a sol-gel method and tested as catalytic material for the partial oxidation of n-dodecane. MoO2 nanoparticles supported on SiO2 are °C, which is a typical reforming temperature for n-dodecane. The formation of Mo O Si bonds at the interface between MoO2 nanoparticles and SiO2 support appear to be responsible for the enhanced stability to sintering displayed by the nanoparticles. As a result of this particle size stabilization, SiO2 supported MoO2 nanoparticles show an improved reforming activity in terms of syngas generation compared to micron-size commercial MoO2. Thus, commercial MoO2 exhibits a good initial activity at space velocities up to 15 h−1, but showing only gas-phase reactions at larger values. Conversely, MoO2 nanoparticles supported on SiO2 show a high initial reforming activity (e.g., 69% H2 yield, 82% CO yield and 100% carbon conversion) even at space velocities up to 30 h−1. Supported MoO2 nanoparticles also show good stability for the partial oxidation of n-dodecane at 850 ◦C without any sign of deactivation during the first 24 h on-stream

Enabling Grant-Free URLLC for AoI Minimization in RAN-Coordinated 5G Health Monitoring System

Age of information (AoI) is used to evaluate the performance of 5G health monitoring systems because stale data can be fatal for patients with serious illness. Recently, grant-free ultra-reliable and low latency communications (URLLC) have shown greater potential of minimizing AoI than conventional grant-based approaches; however, existing grant-free schedulers cannot provide guaranteed performance in 5G health monitoring systems because they involve two fundamental problems in time and frequency domains, namely the joint scheduling problem and physical resource block (PRB) allocation. In this study, we investigate two resource allocation problems for the first time, aiming to enable grant-free URLLC to minimize AoI in 5G health monitoring systems. Specifically, we propose two adaptive solutions based on an open radio access network-coordinated wireless system: 1) a joint scheduling algorithm and 2) an adaptive PRB allocation algorithm. To verify the effectiveness of the proposed solutions, we built a simulation environment similar to a real health monitoring system and captured the performance variations under realistic deployment scenarios

Primary Squamous Cell Carcinoma in the Testis: A Case Report

A 51-yr-old man presented with an enlarged right testis for two months. The radically resected testis showed a relatively well-circumscribed ovoid mass, nearly replacing the normal architecture with central cystic changes. Microscopically, the mass was composed of ovoid shaped tumor cells of a moderately differentiated squamous cell carcinoma (SCC). The central portion of the mass was filled with well-formed laminated keratinous materials and the remnant cavity lined by dysplastic squamous epithelium, indicated SCC may be derived from an epidermal cyst. SCC is among the most common types of neoplasm afflicting human beings, but it is rare in the testis. To our knowledge, this is the second report of the testicular squamous cell carcinoma occurring in a patient without other primary tumors, and the firstly reported case in Korea

Systematic Analysis of Poly(o-aminophenol) Humidity Sensors

This is the final version. Available on open access from the American Chemical Society via the DOI in this recordA thin film of poly(o-aminophenol), POAP, has been used as a sensor for various types of toxic and nontoxic gases: a gateway between the digital and physical worlds. We have carried out a systematic mechanistic investigation of POAP as a humidity sensor; how does it sense different gases? POAP has several convenient features such as flexibility, transparency, and suitability for large-scale manufacturing. With an appropriate theoretical method, molecular oligomers of POAP, NH and O functional groups and the perpendicular side of the polymeric body, are considered as attacking sites for humidity sensing. It is found that the NH position of the polymer acts as an electrophilic center: able to accept electronic cloud density and energetically more favorable compared to the O site. The O site acts as a nucleophilic center and donates electronic cloud density toward H2Ovap. In conclusion, only these two sites are involved in the sensing process which leads to strong intermolecular hydrogen bonding, having a 1.96 Å bond distance and ΔE ∼ -35 kcal mol-1. The results suggest that the sensitivity of the sensor improved with the oxidization state of POAP.Higher Education Commission (HEC) Islamabad, Pakista

Spontaneous Resolution of IgG4-Related Hepatic Inflammatory Pseudotumor Mimicking Malignancy

Hepatic inflammatory pseudotumor (IPT) is characterized by a well-circumscribed benign tumor mimicking or often mistaken for a malignant lesion. A 48-year-old male presented to the hospital with complaints of epigastric pain, with initial laboratory findings showing mildly elevated alkaline phosphatase (140 U/L) with normal AST, ALT, bilirubin, and lipase, a CD4 count of 384, and an HIV viral load of > 10 million copies. The total IgG level was elevated to 2,228 mg/dL (normal IgG4 level 114 mg/dL). Contrast-enhanced MRI of the abdomen showed heterogeneous mass-like infiltration in the right lobe of the liver measuring 9.6 cm. The liver mass was biopsied which showed dense collagenous fibrosis with abundant lymphoplasmacytic infiltrates with 18 IgG4-positive plasma cells per high-power field. The patient was not given any treatment for this IPT. For more than 1 year of follow-up triple-phase CT scan of the liver was repeated, which showed no liver mass. As radiological images of hepatic IPTs, including IgG4-related hepatic IPT, mimic liver malignancy, histological analysis of the biopsy remains the cornerstone for the diagnosis. Symptomatic patients with IgG4-related hepatic IPT have shown improvement with corticosteroid use; however, spontaneous resolution has also been reported like in the present case

Personality, gender, and age in the language of social media: the open-vocabulary approach

We analyzed 700 million words, phrases, and topic instances collected from the Facebook messages of 75,000 volunteers, who also took standard personality tests, and found striking variations in language with personality, gender, and age. In our open-vocabulary technique, the data itself drives a comprehensive exploration of language that distinguishes people, finding connections that are not captured with traditional closed-vocabulary word-category analyses. Our analyses shed new light on psychosocial processes yielding results that are face valid (e.g., subjects living in high elevations talk about the mountains), tie in with other research (e.g., neurotic people disproportionately use the phrase ‘sick of’ and the word ‘depressed’), suggest new hypotheses (e.g., an active life implies emotional stability), and give detailed insights (males use the possessive ‘my’ when mentioning their ‘wife’ or ‘girlfriend’ more often than females use ‘my’ with ‘husband’ or 'boyfriend’). To date, this represents the largest study, by an order of magnitude, of language and personalit

How does morphology impact on diastolic function in hypertrophic cardiomyopathy? A single centre experience.

Objectives It is unclear if morphology impacts on diastole in hypertrophic cardiomyopathy (HCM). We sought to determine the relationship between various parameters of diastolic function and morphology in a large HCM cohort. Setting Tertiary referral centre from Stanford, California, USA. Partecipants 383 patients with HCM and normal systolic function between 1999 and 2011. A group of 100 prospectively recruited age-matched and sex-matched healthy participants were used as controls. Primary and secondary outcome measures Echocardiograms were assessed by two blinded board-certified cardiologists. HCM morphology was classified as described in the literature (reverse, sigmoid, symmetric, apical and undefined). Results Reverse curvature morphology was most commonly observed (218 (57%). Lateral mitral annular E′40 mL/m2 was present in 47% in reverse curvature, 33% in sigmoid, 32% in symmetric, 37% in apical and 32% in undefined, p=0.09. Each morphology showed altered parameters of diastolic function when compared with the control population. Left ventricular (LV) obstruction was independently associated with all three diastolic parameters considered, in particular with LAVi>40 mL/m2 (OR 2.04 (95% CI 1.23 to 3.39), p=0.005), E/E′>15 (OR 4.66 (95% CI 2.51 to 8.64), p<0.001) and E′<8 (OR 2.55 (95% CI 1.42 to 4.53), p=0.001). Other correlates of diastolic dysfunction were age, LV wall thickness and moderate-to-severe mitral regurgitation. Conclusions In HCM, diastolic dysfunction is present to similar degrees independently from the morphological pattern. The main correlates of diastolic dysfunction are LV obstruction, age, degree of hypertrophy and degree of mitral regurgitation

A bayesian meta-analysis of multiple treatment comparisons of systemic regimens for advanced pancreatic cancer

© 2014 Chan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Background: For advanced pancreatic cancer, many regimens have been compared with gemcitabine (G) as the standard arm in randomized controlled trials. Few regimens have been directly compared with each other in randomized controlled trials and the relative efficacy and safety among them remains unclear