The Hybrid Hanger: A lightweight, portable hang-on tree stand with high durability and ease of use.

The Hybrid Hanger is a fully carbon fiber-epoxy composite hang-on tree stand. This 12-pound tree stand design allows a hunter to carry the stand further without fatiguing, which is perfect for public land hunters. In order to support the weight of a person and the harshness of hunting environments, the Hybrid Hanger will need to be strong and weather resistant. It has been tested to 600 pounds and the carbon fiber is an improvement upon the current metal stands of today’s market. Other qualities of the Hybrid Hanger that improve upon current tree stands in the market include: noise reduction, corrosion 41 resistance, and the compact and sleek design. The Hybrid Hanger will also be foldable with backpack straps to easily carry on a hunter’s back as they walk to their hunting location.https://openriver.winona.edu/urc2019/1021/thumbnail.jp

Thiol-based antioxidant supplementation alters human skeletal muscle signaling and attenuates its inflammatory response and recovery after intense eccentric exercise

Background: The major thiol-disulfide couple of reduced glutathione (GSH) and oxidized glutathione is a key regulator of major transcriptional pathways regulating aseptic inflammation and recovery of skeletal muscle after aseptic injury. Antioxidant supplementation may hamper exercise-induced cellular adaptations. Objective: The objective was to examine how thiol-based antioxidant supplementation affects skeletal muscle's performance and redox-sensitive signaling during the inflammatory and repair phases associated with exercise-induced microtrauma. Design: In a double-blind, crossover design, 10 men received placebo or N-acetylcysteine (NAC; 20 mg . kg(-1) . d(-1)) after muscle-damaging exercise (300 eccentric contractions). In each trial, muscle performance was measured at baseline, after exercise, 2 h after exercise, and daily for 8 consecutive days. Muscle biopsy samples from vastus lateralis and blood samples were collected before exercise and 2 h, 2 d, and 8 d after exercise. Results: NAC attenuated the elevation of inflammatory markers of muscle damage (creatine kinase activity, C-reactive protein, proinflammatory cytokines), nuclear factor kappa B phosphorylation, and the decrease in strength during the first 2 d of recovery. NAC also blunted the increase in phosphorylation of protein kinase B, mammalian target of rapamycin, p70 ribosomal S6 kinase, ribosomal protein S6, and mitogen activated protein kinase p38 at 2 and 8 d after exercise. NAC also abolished the increase in myogenic determination factor and reduced tumor necrosis factor-alpha 8 d after exercise. Performance was completely recovered only in the placebo group. Conclusion: Although thiol-based antioxidant supplementation enhances GSH availability in skeletal muscle, it disrupts the skeletal muscle inflammatory response and repair capability, potentially because of a blunted activation of redox-sensitive signaling pathways