Protocol biopsies in renal transplantation: Prognostic value of structural monitoring

The natural history of renal allograft damage has been characterized in serial protocol biopsies. The prevalence of subclinical rejection (SCR) is maximal during the first months and it is associated with the progression of interstitial fibrosis/tubular atrophy (IF/TA) and a decreased graft survival. IF/TA rapidly progress during the first months and constitutes an independent predictor of graft survival. IF/TA associated with transplant vasculopathy, SCR, or transplant glomerulopathy implies a poorer prognosis than IF/TA without additional lesions. These observations suggest that protocol biopsies could be considered a surrogate of graft survival. Preliminary data suggest that the predictive value of protocol biopsies is not inferior to acute rejection or renal function. Additionally, protocol biopsies have been employed as a secondary efficacy variable in clinical trials. This strategy has been useful to demonstrate a decrease in the progression of IF/TA in some calcineurin-free regimens. Quantification of renal damage is associated with graft survival suggesting that quantitative parameters might improve the predictive value of protocol biopsies. Validation of protocol biopsies as a surrogate of graft survival is actively pursued, as the utility of classical surrogates of graft outcome such as acute rejection has become less useful because of its decreased prevalence with actual immunosuppression

PPROC, an ontology for transparency in'public procurement

Public procurement or tendering refers to the process followed by public authorities for the procurement of goods and services. In most developed countries, the law requires public authorities to provide online information to ensure competitive tendering as far as possible, for which the adequate announcement of tenders is an essential requirement. In addition, transparency laws being proposed in such countries are making the monitoring of public contracts by citizens a fundamental right. This paper describes the PPROC ontology, which has been developed to give support to both processes, publication and accountability, by semantically describing public procurement processes and contracts. The PPROC ontology is extensive, since it covers not only the usual data about the tender, its objectives, deadlines and awardees, but also details of the whole process, from the initial contract publication to its termination. This makes it possible to use the ontology for both open data publication purposes and for the overall management of the public contract procurement process

Modeling flocks with perceptual agents from a dynamicist perspective

Computational simulations of flocks and crowds have typically been processed by a set of logic or syntactic rules. In recent decades, a new generation of systems has emerged from dynamicist approaches in which the agents and the environment are treated as a pair of dynamical systems coupled informationally and mechanically. Their spontaneous interactions allow them to achieve the desired behavior. The main proposition assumes that the agent does not need a full model or to make inferences before taking actions; rather, the information necessary for any action can be derived from the environment with simple computations and very little internal state. In this paper, we present a simulation framework in which the agents are endowed with a sensing device, an oscillator network as controller and actuators to interact with the environment. The perception device is designed as an optic array emulating the principles of the animal retina, which assimilates stimuli resembling optic flow to be captured from the environment. The controller modulates informational variables to action variables in a sensory-motor flow. Our approach is based on the Kuramoto model that describes mathematically a network of coupled phase oscillators and the use of evolutionary algorithms, which is proved to be capable of synthesizing minimal synchronization strategies based on the dynamical coupling between agents and environment. We carry out a comparative analysis with classical implementations taking into account several criteria. It is concluded that we should consider replacing the metaphor of symbolic information processing by that of sensory-motor coordination in problems of multi-agent organizations

Building Fuzzy Elevation Maps from a Ground-based 3D Laser Scan for Outdoor Mobile Robots

Mandow, A; Cantador, T.J.; Reina, A.J.; Martínez, J.L.; Morales, J.; García-Cerezo, A. "Building Fuzzy Elevation Maps from a Ground-based 3D Laser Scan for Outdoor Mobile Robots," Robot2015: Second Iberian Robotics Conference, Advances in Robotics, (2016) Advances in Intelligent Systems and Computing, vol. 418. This is a self-archiving copy of the author’s accepted manuscript. The final publication is available at Springer via http://link.springer.com/book/10.1007/978-3-319-27149-1.The paper addresses terrain modeling for mobile robots with fuzzy elevation maps by improving computational speed and performance over previous work on fuzzy terrain identification from a three-dimensional (3D) scan. To this end, spherical sub-sampling of the raw scan is proposed to select training data that does not filter out salient obstacles. Besides, rule structure is systematically defined by considering triangular sets with an unevenly distributed standard fuzzy partition and zero order Sugeno-type consequents. This structure, which favors a faster training time and reduces the number of rule parameters, also serves to compute a fuzzy reliability mask for the continuous fuzzy surface. The paper offers a case study using a Hokuyo-based 3D rangefinder to model terrain with and without outstanding obstacles. Performance regarding error and model size is compared favorably with respect to a solution that uses quadric-based surface simplification (QSlim).This work was partially supported by the Spanish CICYT project DPI 2011-22443, the Andalusian project PE-2010 TEP-6101, and Universidad de Málaga-Andalucía Tech

The Carnegie Supernova Project I: photometry data release of low-redshift stripped-envelope supernovae

The first phase of the Carnegie Supernova Project (CSP-I) was a dedicated supernova follow-up program based at the Las Campanas Observatory that collected science data of young, low-redshift supernovae between 2004 and 2009. Presented in this paper is the CSP-I photometric data release of low-redshift stripped-envelope core-collapse supernovae. The data consist of optical (uBgVri) photometry of 34 objects, with a subset of 26 having near-infrared (YJH) photometry. Twenty objects have optical pre-maximum coverage with a subset of 12 beginning at least five days prior to the epoch of B-band maximum brightness. In the near-infrared, 17 objects have pre-maximum observations with a subset of 14 beginning at least five days prior to the epoch of J-band maximum brightness. Analysis of this photometric data release is presented in companion papers focusing on techniques to estimate host-galaxy extinction (Stritzinger et al., submitted) and the light-curve and progenitor star properties of the sample (Taddia et al., submitted). The analysis of an accompanying visual-wavelength spectroscopy sample of ~150 spectra will be the subject of a future paper.Comment: Updated a couple of small error

The Carnegie Supernova Project. I. Third Photometry Data Release of Low-redshift Type Ia Supernovae and Other White Dwarf Explosions

We present final natural-system optical (ugriBV) and near-infrared (YJH) photometry of 134 supernovae (SNe) with probable white dwarf progenitors that were observed in 2004-2009 as part of the first stage of the Carnegie Supernova Project (CSP-I). The sample consists of 123 Type Ia SNe, 5 Type Iax SNe, 2 super-Chandrasekhar SN candidates, 2 Type Ia SNe interacting with circumstellar matter, and 2 SN 2006bt-like events. The redshifts of the objects range from to 0.0835; the median redshift is 0.0241. For 120 (90%) of these SNe, near-infrared photometry was obtained. Average optical extinction coefficients and color terms are derived and demonstrated to be stable during the five CSP-I observing campaigns. Measurements of the CSP-I near-infrared bandpasses are also described, and near-infrared color terms are estimated through synthetic photometry of stellar atmosphere models. Optical and near-infrared magnitudes of local sequences of tertiary standard stars for each supernova are given, and a new calibration of Y-band magnitudes of the Persson et al. standards in the CSP-I natural system is presented.Fil: Krisciunas, Kevin. Texas A&M University; Estados UnidosFil: Contreras, Carlos. University Aarhus; Dinamarca. Las Campanas Observatory; ChileFil: Burns, Christopher R.. Las Campanas Observatory; ChileFil: Phillips, M. M.. Las Campanas Observatory; ChileFil: Stritzinger, Maximilian D.. Las Campanas Observatory; Chile. University Aarhus; DinamarcaFil: Morrell, Nidia Irene. Las Campanas Observatory; ChileFil: Hamuy, Mario. Universidad de Chile; ChileFil: Anais, Jorge. Las Campanas Observatory; ChileFil: Boldt, Luis. Las Campanas Observatory; ChileFil: Busta, Luis. Las Campanas Observatory; ChileFil: Campillay, Abdo. Las Campanas Observatory; ChileFil: Castellón, Sergio. Las Campanas Observatory; ChileFil: Folatelli, Gaston. Las Campanas Observatory; Chile. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas; ArgentinaFil: Freedman, Wendy L.. University of Chicago; Estados UnidosFil: González, Consuelo. Las Campanas Observatory; ChileFil: Hsiao, Eric Y.. Florida State University; Estados Unidos. University Aarhus; Dinamarca. Las Campanas Observatory; ChileFil: Krzeminski, Wojtek. Las Campanas Observatory; ChileFil: Persson, Sven Eric. Carnegie Observatories;Fil: Roth, Miguel. Gmto Corporation; Chile. Las Campanas Observatory; ChileFil: Salgado, Francisco. Leiden Observatory Research Institute; . Las Campanas Observatory; ChileFil: Serón, Jacqueline. Las Campanas Observatory; Chile. Cerro Tololo Inter American Observatory; ChileFil: Suntzeff, Nicholas B.. Texas A&M University; Estados UnidosFil: Torres, Simón. Soar Telescope; Chile. Las Campanas Observatory; ChileFil: Filippenko, Alexei V.. University of California at Berkeley; Estados UnidosFil: Li, Weidong. University of California at Berkeley; Estados UnidosFil: Madore, Barry F.. Jet Propulsion Laboratory, California Institute Of Technology; . Las Campanas Observatory; ChileFil: DePoy, D.L.. Texas A&M University; Estados UnidosFil: Marshall, Jennifer L.. Texas A&M University; Estados UnidosFil: Rheault, Jean Philippe. Texas A&M University; Estados UnidosFil: Villanueva, Steven. Texas A&M University; Estados Unidos. Ohio State University; Estados Unido

Implementación de un sistema de información geográfica en municipios de la zona norte de la provincia de Santa Cruz

Los Sistemas de Información Geográfica, nacen de la necesidad constante de la sociedad de obtener información acerca de los territorios, constituyendo uno de los campos más dinámicos y novedosos de aplicación de la Informática, con un indudable efecto en la sociedad. Este artículo pretende presentar la iniciativa de investigación acerca de Sistemas de Información Geográfica (SIG) en general, y en particular aplicados en la Subsecretaría de Planeamiento de la Municipalidad de Caleta Olivia (MCO), en la provincia de Santa Cruz, en áreas tales como Catastro, Obras Particulares, Tierras, Topografía, Infraestructura Urbana y Producción. Esta investigación se está realizando en el Laboratorio de Tecnologías Emergentes de la Universidad Nacional de la Patagonia Austral, con el objetivo de desarrollar una aplicación de Software Libre y permitir la unificación de la información de dicha Municipalidad que posibilite agilizar la gestión administrativa.Eje: Ingeniería de Software y Base de DatosRed de Universidades con Carreras en Informática (RedUNCI

Carnegie Supernova Project-II: Extending the Near-Infrared Hubble Diagram for Type Ia Supernovae to z∼0.1z\sim0.1

The Carnegie Supernova Project-II (CSP-II) was an NSF-funded, four-year program to obtain optical and near-infrared observations of a "Cosmology" sample of $\sim100$ Type Ia supernovae located in the smooth Hubble flow ($0.03 \lesssim z \lesssim 0.10$). Light curves were also obtained of a "Physics" sample composed of 90 nearby Type Ia supernovae at $z \leq 0.04$ selected for near-infrared spectroscopic time-series observations. The primary emphasis of the CSP-II is to use the combination of optical and near-infrared photometry to achieve a distance precision of better than 5%. In this paper, details of the supernova sample, the observational strategy, and the characteristics of the photometric data are provided. In a companion paper, the near-infrared spectroscopy component of the project is presented.Comment: 43 pages, 10 figures, accepted for publication in PAS

Implementación de un sistema de información geográfica en municipios de la zona norte de la provincia de Santa Cruz

Los Sistemas de Información Geográfica, nacen de la necesidad constante de la sociedad de obtener información acerca de los territorios, constituyendo uno de los campos más dinámicos y novedosos de aplicación de la Informática, con un indudable efecto en la sociedad. Este artículo pretende presentar la iniciativa de investigación acerca de Sistemas de Información Geográfica (SIG) en general, y en particular aplicados en la Subsecretaría de Planeamiento de la Municipalidad de Caleta Olivia (MCO), en la provincia de Santa Cruz, en áreas tales como Catastro, Obras Particulares, Tierras, Topografía, Infraestructura Urbana y Producción. Esta investigación se está realizando en el Laboratorio de Tecnologías Emergentes de la Universidad Nacional de la Patagonia Austral, con el objetivo de desarrollar una aplicación de Software Libre y permitir la unificación de la información de dicha Municipalidad que posibilite agilizar la gestión administrativa.Eje: Ingeniería de Software y Base de DatosRed de Universidades con Carreras en Informática (RedUNCI

The Carnegie Supernova Project II. The shock wave revealed through the fog: The strongly interacting Type IIn SN 2013L

We present ultra-violet to mid-infrared observations of the long-lasting Type IIn supernova (SN) 2013L obtained by the Carnegie Supernova Project II (CSP-II). The spectra of SN 2013L are dominated by H emission features characterized by three components attributed to different regions. A unique feature of this Type IIn SN is that the blue shifted line profile is dominated by the macroscopic velocity of the expanding shock wave of the SN. We are therefore able to trace the evolution of the shock velocity in the dense and partially opaque circumstellar medium (CSM), from $\sim 4800~km~s^{-1}$ at +48 d, decreasing as $t^{-0.23}$ to $\sim 2700~km~s^{-1}$ after a year. We perform spectral modeling of both the broad- and intermediate-velocity components of the H$\alpha$ line profile. The high-velocity component is consistent with emission from a radially thin, spherical shell located behind the expanding shock with emission wings broadened by electron scattering. We propose that the intermediate component originates from pre-ionized gas from the unshocked dense CSM with the same velocity as the narrow component, $\sim 100~km~s^{-1}$, but also broadened by electron scattering. The spectral energy distributions (SEDs) of SN 2013L after +132 d are well reproduced by a two-component black-body (BB) model. The circumstellar-interaction model of the bolometric light curve reveals a mass-loss rate history with large values ($1.7\times 10^{-2} - 0.15~M_\odot~yr^{-1}$) over the $\sim$25 - 40 years before explosion. The drop in the light curve at $\sim 350$ days and presence of electron scattering wings at late epochs indicate an anisotropic CSM. The mass-loss rate values and the unshocked CSM velocity are consistent with the characteristics of a massive star, such as a luminous blue variable (LBV) undergoing strong eruptions, similar to $\eta$ Carina.Comment: Replaced after language editor corrections, accepted for publication on Astronomy and Astrophysics, 43 pages, 29 figures. Abstract abridge