176 research outputs found

    Explicit CP violation in the Dine-Seiberg-Thomas model

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    The possibility of explicit CP violation is studied in a supersymmetric model proposed by Dine, Seiberg, and Thomas, with two effective dimension-five operators. The explicit CP violation may be triggered by complex phases in the coefficients for the dimension-five operators in the Higgs potential, and by a complex phase in the scalar top quark masses. Although the scenario of explicit CP violation is found to be inconsistent with the experimental data at LEP2 at the tree level, it may be possible at the one-loop level. For a reasonable parameter space, the masses of the neutral Higgs bosons and their couplings to a pair of ZZ bosons are consistent with the LEP2 data, at the one-loop level.Comment: 5 pages, 2 figure

    Alpha-synuclein: a pathological factor with Aβ and tau and biomarker in Alzheimers disease

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    Abstract Background Alpha-synuclein (α-syn) is considered the main pathophysiological protein component of Lewy bodies in synucleinopathies. α-Syn is an intrinsically disordered protein (IDP), and several types of structural conformations have been reported, depending on environmental factors. Since IDPs may have distinctive functions depending on their structures, α-syn can play different roles and interact with several proteins, including amyloid-beta (Aβ) and tau, in Alzheimers disease (AD) and other neurodegenerative disorders. Main body In previous studies, α-syn aggregates in AD brains suggested a close relationship between AD and α-syn. In addition, α-syn directly interacts with Aβ and tau, promoting mutual aggregation and exacerbating the cognitive decline. The interaction of α-syn with Aβ and tau presented different consequences depending on the structural forms of the proteins. In AD, α-syn and tau levels in CSF were both elevated and revealed a high positive correlation. Especially, the CSF α-syn concentration was significantly elevated in the early stages of AD. Therefore, it could be a diagnostic marker of AD and help distinguish AD from other neurodegenerative disorders by incorporating other biomarkers. Conclusion The overall physiological and pathophysiological functions, structures, and genetics of α-syn in AD are reviewed and summarized. The numerous associations of α-syn with Aβ and tau suggested the significance of α-syn, as a partner of the pathophysiological roles in AD. Understanding the involvements of α-syn in the pathology of Aβ and tau could help address the unresolved issues of AD. In particular, the current status of the CSF α-syn in AD recommends it as an additional biomarker in the panel for AD diagnosis

    Non-Drude Optical Conductivity of (III,Mn)V Ferromagnetic Semiconductors

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    We present a numerical model study of the zero-temperature infrared optical properties of (III,Mn)V diluted magnetic semiconductors. Our calculations demonstrate the importance of treating disorder and interaction effects simultaneously in modelling these materials. We find that the conductivity has no clear Drude peak, that it has a broadened inter-band peak near 220 meV, and that oscillator weight is shifted to higher frequencies by stronger disorder. These results are in good qualitative agreement with recent thin film absorption measurements. We use our numerical findings to discuss the use of f-sum rules evaluated by integrating optical absorption data for accurate carrier-density estimates.Comment: 7 pages, 3 figure

    Photometric Redshifts in the North Ecliptic Pole Wide Field based on a Deep Optical Survey with Hyper Suprime-Cam

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    The AKARIAKARI space infrared telescope has performed near- to mid-infrared (MIR) observations on the North Ecliptic Pole Wide (NEPW) field (5.4 deg2^2) for about one year. AKARIAKARI took advantage of its continuous nine photometric bands, compared with NASA's SpitzerSpitzer and WISE space telescopes, which had only four filters with a wide gap in the MIR. The AKARIAKARI NEPW field lacked deep and homogeneous optical data, limiting the use of nearly half of the IR sources for extra-galactic studies owing to the absence of photometric redshifts (photo-zs). To remedy this, we have recently obtained deep optical imaging over the NEPW field with 5 bands (gg, rr, ii, zz, and YY) of the Hyper Suprime-Camera (HSC) on the Subaru 8m telescope. We optically identify AKARI-IR sources along with supplementary SpitzerSpitzer and WISE data as well as pre-existing optical data. In this work, we derive new photo-zs using a χ2\chi^2 template-fitting method code (LeLe PharePhare) and reliable photometry from 26 selected filters including HSC, AKARIAKARI, CFHT, Maidanak, KPNO, SpitzerSpitzer and WISE data. We take 2026 spectroscopic redshifts (spec-z) from all available spectroscopic surveys over the NEPW to calibrate and assess the accuracy of the photo-zs. At z < 1.5, we achieve a weighted photo-z dispersion of σΔz/(1+z)\sigma_{\Delta{z/(1+z)}} = 0.053 with η\eta = 11.3% catastrophic errors.Comment: 20 pages, 13 figures, accepted for publication in MNRAS. For summary video, please see http://youtu.be/hjNJRCoBIg

    Cause of Chest Pain in a Patient with Previous Myocardial Infarction: Look Outside the Heart for Extracardiac Mass

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    We report a case of thymic carcinoma that was initially detected by echocardiography in an 80-year-old male who visited the emergency room for chest pain and had a history of myocardial infarction and percutaneous coronary intervention. Transthoracic echocardiography showed a huge extracardiac mass that was located in the anterior mediastinum and was diagnosed as a thymic carcinoma by biopsy

    S2COSMOS: evolution of gas mass with redshift using dust emission

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    We investigate the evolution of the gas mass fraction for galaxies in the COSMOS field using submillimetre emission from dust at 850μm. We use stacking methodologies on the 850 μm S2COSMOS map to derive the gas mass fraction of galaxies out to high redshifts, 0 ≤ z ≤ 5, for galaxies with stellar masses of 109.
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