29 research outputs found
X-shooter, NACO, and AMBER observations of the LBV Pistol Star \footnote{Based on ESO runs 85.D-0182A, 085.D-0625AC}
We present multi-instruments and multi-wavelengths observations of the famous
LBV star Pistol Star. These observations are part of a larger program about
early O stars at different metallicities. The Pistol star has been claimed as
the most massive star known, with 250 solar masses. We present the preliminary
results based on X-Shooter spectra, as well as the observations performed with
the VLTI-AMBER and the VLT-NACO adaptive optics. The X-shooter spectrograph
allows to obtain simultaneously a spectrum from the UV to the K-band with a
resolving power of 15000. The preliminary results obtained indicate that
Pistol Star has similar properties of Eta Car, including shells of matter, but
also the binarity. Other objects of the program, here briefly presented, were
selected for their particular nature: early O stars with mass discrepancies
between stellar evolution models and observations, discrepancies with the wind
momentum luminosity relation.Comment: Poster at the 39th LIAC, submitted version of the proceeding
High-angular resolution observations of the Pistol Star
First results of near-IR adaptive optics (AO)-assisted imaging,
interferometry, and spectroscopy of this Luminous Blue Variable (LBV) are
presented. They suggest that the Pistol Star is at least double. If the
association is physical, it would reinforce questions concerning the importance
of multiplicity for the formation and evolution of extremely massive stars.Comment: poster at IAUS27
Luminous blue variables: An imaging perspective on their binarity and near environment
Luminous blue variables (LBVs) are rare massive stars with very high
luminosity. They are characterized by strong photo-metric and spectroscopic
variability related to transient eruptions. The mechanisms at the origin of
these eruptions is not well known. In addition, their formation is still
problematic and the presence of a companion could help to explain how they
form. Aims. This article presents a study of seven LBVs (about 20% of the known
Galactic population), some Wolf-Rayet stars, and massive binaries. We probe the
environments that surround these massive stars with near-, mid-, and
far-infrared images, investigating potential nebula/shells and the companion
stars. Methods. To investigate large spatial scales, we used seeing-limited and
near diffraction-limited adaptive optics images to obtain a differential
diagnostic on the presence of circumstellar matter and to determine their
extent. From those images, we also looked for the presence of binary companions
on a wide orbit. Once a companion was detected, its gravitational binding to
the central star was tested. Tests include the chance projection probability,
the proper motion estimates with multi-epoch observations, flux ratio, and star
separations. Results. We find that two out of seven of LBVs may have a wide
orbit companion. Most of the LBVs display a large circumstellar envelope or
several shells. In particular, HD168625, known for its rings, possesses several
shells with possibly a large cold shell at the edge of which the rings are
formed. For the first time, we have directly imaged the companion of LBV stars
Oxidative stress and life histories: unresolved issues and current needs.
Life-history theory concerns the trade-offs that mold the patterns of investment by animals between reproduction, growth, and survival. It is widely recognized that physiology plays a role in the mediation of life-history trade-offs, but the details remain obscure. As life-history theory concerns aspects of investment in the soma that influence survival, understanding the physiological basis of life histories is related, but not identical, to understanding the process of aging. One idea from the field of aging that has gained considerable traction in the area of life histories is that life-history trade-offs may be mediated by free radical production and oxidative stress. We outline here developments in this field and summarize a number of important unresolved issues that may guide future research efforts. The issues are as follows. First, different tissues and macromolecular targets of oxidative stress respond differently during reproduction. The functional significance of these changes, however, remains uncertain. Consequently there is a need for studies that link oxidative stress measurements to functional outcomes, such as survival. Second, measurements of oxidative stress are often highly invasive or terminal. Terminal studies of oxidative stress in wild animals, where detailed life-history information is available, cannot generally be performed without compromising the aims of the studies that generated the life-history data. There is a need therefore for novel non-invasive measurements of multi-tissue oxidative stress. Third, laboratory studies provide unrivaled opportunities for experimental manipulation but may fail to expose the physiology underpinning life-history effects, because of the benign laboratory environment. Fourth, the idea that oxidative stress might underlie life-history trade-offs does not make specific enough predictions that are amenable to testing. Moreover, there is a paucity of good alternative theoretical models on which contrasting predictions might be based. Fifth, there is an enormous diversity of life-history variation to test the idea that oxidative stress may be a key mediator. So far we have only scratched the surface. Broadening the scope may reveal new strategies linked to the processes of oxidative damage and repair. Finally, understanding the trade-offs in life histories and understanding the process of aging are related but not identical questions. Scientists inhabiting these two spheres of activity seldom collide, yet they have much to learn from each other
Mitochondrial physiology
As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery
Mitochondrial physiology
As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery
Effects of formoterol and ipratropium bromide on repeated cadmium inhalation -induced pulmonary inflammation and emphysema in rats
Recommended from our members
Oxidative stress and life histories: unresolved issues and current needs.
Life-history theory concerns the trade-offs that mold the patterns of investment by animals between reproduction, growth, and survival. It is widely recognized that physiology plays a role in the mediation of life-history trade-offs, but the details remain obscure. As life-history theory concerns aspects of investment in the soma that influence survival, understanding the physiological basis of life histories is related, but not identical, to understanding the process of aging. One idea from the field of aging that has gained considerable traction in the area of life histories is that life-history trade-offs may be mediated by free radical production and oxidative stress. We outline here developments in this field and summarize a number of important unresolved issues that may guide future research efforts. The issues are as follows. First, different tissues and macromolecular targets of oxidative stress respond differently during reproduction. The functional significance of these changes, however, remains uncertain. Consequently there is a need for studies that link oxidative stress measurements to functional outcomes, such as survival. Second, measurements of oxidative stress are often highly invasive or terminal. Terminal studies of oxidative stress in wild animals, where detailed life-history information is available, cannot generally be performed without compromising the aims of the studies that generated the life-history data. There is a need therefore for novel non-invasive measurements of multi-tissue oxidative stress. Third, laboratory studies provide unrivaled opportunities for experimental manipulation but may fail to expose the physiology underpinning life-history effects, because of the benign laboratory environment. Fourth, the idea that oxidative stress might underlie life-history trade-offs does not make specific enough predictions that are amenable to testing. Moreover, there is a paucity of good alternative theoretical models on which contrasting predictions might be based. Fifth, there is an enormous diversity of life-history variation to test the idea that oxidative stress may be a key mediator. So far we have only scratched the surface. Broadening the scope may reveal new strategies linked to the processes of oxidative damage and repair. Finally, understanding the trade-offs in life histories and understanding the process of aging are related but not identical questions. Scientists inhabiting these two spheres of activity seldom collide, yet they have much to learn from each other
X-shooter, NACO, and AMBER observations of the LBV Pistol Star
International audienceWe present multi-instrument and multi-wavelength observations of the famous LBV star Pistol Star. These observations are part of a larger program on early O stars at different metallicities. The Pistol Star has been claimed to be one of the most massive star known, with 250 solar masses. We present preliminary results based on X-shooter spectra, as well as observations performed with the VLTI-AMBER and the VLT-NACO adaptive optics. The X-shooter spectrograph provides simultaneously a spectrum from the UV to the K-band with a resolving power of ˜15000. The preliminary results obtained indicate that Pistol Star has similar properties to eta Car, including shells of matter, but is also a binary
X-shooter, NACO, and AMBER observations of the LBV Pistol Star
International audienceWe present multi-instrument and multi-wavelength observations of the famous LBV star Pistol Star. These observations are part of a larger program on early O stars at different metallicities. The Pistol Star has been claimed to be one of the most massive star known, with 250 solar masses. We present preliminary results based on X-shooter spectra, as well as observations performed with the VLTI-AMBER and the VLT-NACO adaptive optics. The X-shooter spectrograph provides simultaneously a spectrum from the UV to the K-band with a resolving power of ˜15000. The preliminary results obtained indicate that Pistol Star has similar properties to eta Car, including shells of matter, but is also a binary