In what ways can Community Integrated Management of Neonatal and Childhood Illnesses (C-IMNCI) improve child health?

Background: In addition to access to quality health services, family child care practices play a major role in improving child health and achieving reduction in childhood mortality.Objective: To assess the effect of community integrated management of neonatal and childhood illness interventions on family practices for child care.Methods: A comparative cross-sectional survey was conducted in Dabat District, northwest Ethiopia. A total of 800 mothers or caretakers of children of under two years form the Community Integrated Management of Childhood Illnesses intervention and non-intervention areas were selected using a multistage sampling procedure and interviewed in November 2007.Result: Three hundred thirty seven (84.3%) of the mothers from the intervention area and 358 (89.5%) from nonintervention area were illiterate. Thre vast majority (99.5%) of the fathers in each of the areas were farmers. Mothers/care takers from community IMNCI intervention areas reported better child care practices in terms of time of breastfeeding initiation (OR=9.10, 95% CI=5.45, 12.43), avoiding prelacteal feeding (OR=11.01, 95% CI=7.98, 15.43), initiation of supplementary feeding (OR=3.63, 95% CI=2.23, 5.93) compared to mothers/care takers form non intervention areas. Regarding water, personal hygiene and environmental sanitation, statistical significant differences were observed in using a safe drinking source of water (OR=6.36, 95% CI=4.49, 9.01) and availability of pit latrines (OR=43.52, 95% CI=25.46, 67.89) between the intervention and non-intervention areas. The likelihood of seeking care for diarrhea was about five times and that of fever is three times higher in the intervention areas compared to the non-intervention one.Conclusion: Community IMNCI has positive effects on child feeding, disease prevention, health care seeking practices and these practices are expected to improve child health and survival. Thus the program needs to be scaled up in other areas. Further studies may assess the actual effect of the intervention on child morbidity and mortality. [Ethiop. J. Health Dev. 2011;25(2):143-149

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The status of rabies in Ethiopia: A retrospective record review

Background: Rabies, a viral disease that affects all warm-blooded animals, is widespread in many regions of the world. Human rabies, transmitted by dogs is an important public health issue in Ethiopia. To-date, effective rabies control program still remains to be a reality and needs to be strengthened..Objective: Reviewing of recorded data to generate information on the status of rabies in Ethiopia for the year 2001-2009.Methods: A retrospective data were used from the Ethiopian Health and Nutrition Research Institute rabies case record book registered between 2001 and 2009.Results: The fatal human cases during the period of study were 386 humans with annual range of 35 to 58. The over all post exposure treatment for humans was 17,204 within and around Addis Ababa. During the same period, 20,414 suspected rabid animals were clinically examined; nevertheless, only 10%were positive for rabies. Among 3,460 animal brains investigated in the laboratory with FAT, 75% were confirmed as rabies positive. The production and distribution of anti-rabies vaccine reached 130,673 treatment doses for human vaccine and 85,055 doses for animal vaccine respectively in the period of 2001-2009.Conclusion: The recorded data showed the underestimate of rabies diagnosis, post exposure prophylaxis and fatal human cases, which could be attributed due to the absence of national rabies surveillance system. Therefore, It is of paramount importance to assess and map the national picture of rabies within a given time interval to launch a national rabies control strategy. [Ethiop. J. Health Dev. 2010;24(2):127-132

An Analysis of Market Integration for Selected Vegetables in Indonesia

IndonesianSayur-sayuran adalah salah satu jenis komoditas penting di Indonesia yang termasuk dalam penyurnbang devisa ekspor nonmigas di Indonesia. Studi ini bertujuan untuk menguji konsep integrasi pasar pada komoditas sayur-sayuran terpilih di Indonesia. Spesifikasi model digunakan merupakan aplikasi model yang kembangkan oleh Ravallion (1986). Empat jenis sayur-sayuran di antara 21 sayuran yang diproduksi di Indonesia dipilih untuk pengujian integrasi pasar. Pemilihan tersebut berdasarkan pada urutan rangking luasan tanam dan hasil panen yang diproduksi selama periode 1969-1990. Hasil uji statistik dengan F-test menunjukkan bahwa tidak ada satu pun kombinasi pasar yang tersegmentasi. Hal ini memberikan implikasi penting bagi petani dan pengambil kebijakan di Indonesia. Hanya beberapa kombinasi pasar sayur-sayuran yang terintegrasi dalam jangka pendek. Hasil lain juga menunjukkan bahwa fasilitas sarana transportasi diantara pasar produsen-konsumen dan sifat karakteristik sayur-sayuran yang mudah rusak (perishable) adalah hal penting dalam menjelaskan faktor yang mempengaruhi kecepatan transmisi harga. Integrasi pasar yang terjadi bersifat langsung (directional) di mana pasar di Jawa Barat dan Jakarta terintegrasi dengan pasar di Sumatera; sedangkan pasar di Jawa Tengah terintegrasi dengan Jawa Timur, Nusa Tenggara Barat dan Sulawesi Selatan

Patterns of language and auditory dysfunction in 6-year-old children with epilepsy

In a previous study we reported difficulty with expressive language and visuoperceptual ability in preschool children with epilepsy and otherwise normal development. The present study analysed speech and language dysfunction for each individual in relation to epilepsy variables, ear preference, and intelligence in these children and described their auditory function. Twenty 6-year-old children with epilepsy (14 females, 6 males; mean age 6:5 y, range 6 y–6 y 11 mo) and 30 reference children without epilepsy (18 females, 12 males; mean age 6:5 y, range 6 y–6 y 11 mo) were assessed for language and auditory ability. Low scores for the children with epilepsy were analysed with respect to speech-language domains, type of epilepsy, site of epileptiform activity, intelligence, and language laterality. Auditory attention, perception, discrimination, and ear preference were measured with a dichotic listening test, and group comparisons were performed. Children with left-sided partial epilepsy had extensive language dysfunction. Most children with partial epilepsy had phonological dysfunction. Language dysfunction was also found in children with generalized and unclassified epilepsies. The children with epilepsy performed significantly worse than the reference children in auditory attention, perception of vowels and discrimination of consonants for the right ear and had more left ear advantage for vowels, indicating undeveloped language laterality

A novel approach to frequency support in a wind integrated power system

This paper discusses the impact of wind penetration on frequency control of a thermal dominated system considering Generation Rate Constraints (GRC) and dead band non-linearities. The hidden inertia emulation and coordinated operation of conventional power generation systems with wind energy can effectively alleviate the frequency excursions during sudden load disturbances. Conventional energy storage device like Flywheel Energy Storage (FES) system can be used in conjunction with wind integrated power system to overcome the intermittent nature of power generation. Thyristor Controlled Series Compensator (TCSC) is found to be effective in damping low frequency oscillations in weak tie-lines and supplement the frequency regulation. A stochastic population based evolutionary computation technique - Particle Swarm Optimization (PSO) is used to tune the controller gains. A strategy comprising inertia control, coordinated operation of conventional generation units with wind energy and TCSC-FES has been proposed to enhance the frequency regulation which is effective in controlling low frequency oscillations as established by the simulation results

The Embryonic Transcriptome Of The Red-Eared Slider Turtle (Trachemys Scripta)

The bony shell of the turtle is an evolutionary novelty not found in any other group of animals, however, research into its formation has suggested that it has evolved through modification of conserved developmental mechanisms. Although these mechanisms have been extensively characterized in model organisms, the tools for characterizing them in non-model organisms such as turtles have been limited by a lack of genomic resources. We have used a next generation sequencing approach to generate and assemble a transcriptome from stage 14 and 17 Trachemys scripta embryos, stages during which important events in shell development are known to take place. The transcriptome consists of 231,876 sequences with an N-50 of 1,166 bp. GO terms and EC codes were assigned to the 61,643 unique predicted proteins identified in the transcriptome sequences. All major GO categories and metabolic pathways are represented in the transcriptome. Transcriptome sequences were used to amplify several cDNA fragments designed for use as RNA in situ probes. One of these, BMP5, was hybridized to a T. scripta embryo and exhibits both conserved and novel expression patterns. The transcriptome sequences should be of broad use for understanding the evolution and development of the turtle shell and for annotating any future T. scripta genome sequences

Is Audio Computer-Assisted Self-Interview (ACASI) Useful in Risk Behaviour Assessment of Female and Male Sex Workers, Mombasa, Kenya?

BACKGROUND: Audio computer-assisted self-interview (ACASI) may elicit more frequent reporting of socially sensitive behaviours than face-to-face (FtF)-interview. However, no study compared responses to both methods in female and male sex workers (FSW; MSW) in Africa. METHODOLOGY/PRINCIPAL FINDINGS: We sequentially enrolled adults recruited for an HIV-1 intervention trial into a comparative study of ACASI and FtF-interview, in a clinic near Mombasa, Kenya. Feasibility and acceptability of ACASI, and a comparative analysis of enrolment responses between ACASI and FtF on an identical risk assessment questionnaire were evaluated. In total, 139 women and 259 men, 81% of eligible cohort participants, completed both interviews. ACASI captured a higher median number of regular (2 vs. 1, p<0.001, both genders) and casual partners in the last week (3 vs. 2, p = 0.04 in women; 2 vs. 1, p<0.001 in men). Group sex (21.6 vs. 13.5%, p<0.001, in men), intravenous drug use (IDU; 10.8 vs. 2.3%, p<0.001 in men; 4.4 vs. 0%, p = 0.03 in women), and rape (8.9 vs. 3.9%, p = 0.002, in men) were reported more frequently in ACASI. A surprisingly high number of women reported in ACASI that they had paid for sex (49.3 vs. 5.8%, p<0.001). Behaviours for recruitment (i.e. anal sex, sex work, sex between males) were reported less frequently in ACASI. The majority of women (79.2%) and men (69.7%) felt that answers given in ACASI were more honest. Volunteers who were not able to take ACASI (84 men, and 37 women) mostly lacked reading skills. CONCLUSIONS/SIGNIFICANCE: About 1 in 5 cohort participants was not able to complete ACASI, mostly for lack of reading skills. Participants who completed ACASI were more likely to report IDU, rape, group sex, and payment for sex by women than when asked in FtF interview. ACASI appears to be a useful tool for high risk behaviour assessments in the African context

Clinical-pathological study on β-APP, IL-1β, GFAP, NFL, Spectrin II, 8OHdG, TUNEL, miR-21, miR-16, miR-92 expressions to verify DAI-diagnosis, grade and prognosis

Traumatic brain injury (TBI) is one of the most important death and disability cause, involving substantial costs, also in economic terms, when considering the young age of the involved subject. Aim of this paper is to report a series of patients treated at our institutions, to verify neurological results at six months or survival; in fatal cases we searched for βAPP, GFAP, IL-1β, NFL, Spectrin II, TUNEL and miR-21, miR-16, and miR-92 expressions in brain samples, to verify DAI diagnosis and grade as strong predictor of survival and inflammatory response. Concentrations of 8OHdG as measurement of oxidative stress was performed. Immunoreaction of β-APP, IL-1β, GFAP, NFL, Spectrin II and 8OHdG were significantly increased in the TBI group with respect to control group subjects. Cell apoptosis, measured by TUNEL assay, were significantly higher in the study group than control cases. Results indicated that miR-21, miR-92 and miR-16 have a high predictive power in discriminating trauma brain cases from controls and could represent promising biomarkers as strong predictor of survival, and for the diagnosis of postmortem traumatic brain injury