269 research outputs found
A support vector-based interval type-2 fuzzy system
In this paper, a new fuzzy regression model that is supported by support vector regression is presented. Type-2 fuzzy systems are able to tackle applications that have significant uncertainty. However general type-2 fuzzy systems are more complex than type-1 fuzzy systems. Support vector machines are similar to fuzzy systems in that they can also model systems that are non-linear in nature. In the proposed model the consequent parameters of type-2 fuzzy rules are learnt using support vector regression and an efficient closed-form type reduction strategy is used to simplify the computations. Support vector regression improved the generalisation performance of the fuzzy rule-based system in which the fuzzy rules were a set of interpretable IF-THEN rules. The performance of the proposed model was demonstrated by conducting case studies for the non-linear system approximation and prediction of chaotic time series. The model yielded promising results and the simulation results are compared to the results published in the area
A support vector-based interval type-2 fuzzy system
In this paper, a new fuzzy regression model that is supported by support vector regression is presented. Type-2 fuzzy systems are able to tackle applications that have significant uncertainty. However general type-2 fuzzy systems are more complex than type-1 fuzzy systems. Support vector machines are similar to fuzzy systems in that they can also model systems that are non-linear in nature. In the proposed model the consequent parameters of type-2 fuzzy rules are learnt using support vector regression and an efficient closed-form type reduction strategy is used to simplify the computations. Support vector regression improved the generalisation performance of the fuzzy rule-based system in which the fuzzy rules were a set of interpretable IF-THEN rules. The performance of the proposed model was demonstrated by conducting case studies for the non-linear system approximation and prediction of chaotic time series. The model yielded promising results and the simulation results are compared to the results published in the area
Peptide-Mediated Constructs of Quantum Dot Nanocomposites for Enzymatic Control of Nonradiative Energy Transfer
Cataloged from PDF version of article.A bottom-up approach for constructing colloidal semiconductor quantum dot (QDot) nanocomposites that facilitate nonradiative Forster-type resonance energy transfer (FRET) using polyelectrolyte peptides was proposed and realized. The electrostatic interaction of these polypeptides with altering chain lengths was probed for thermodynamic, structural, and morphological aspects. The resulting nanocomposite film was successfully cut with the protease by digesting the biomimetic peptide layer upon which the QDot assembly was constructed. The ability to control photoluminescence decay lifetime was demonstrated by proteolytic enzyme activity, opening up new possibilities for biosensor applications
Engineered Peptides for Nanohybrid Assemblies
Cataloged from PDF version of article.Inspired by biological material synthesis, synthetic biomineralization peptides have been screened through a laboratory evolution using biocombinatorial techniques. In this study, using the fine examples in nature, silica binding peptides and gold binding peptides were fused together to form a hybrid peptide. We designed fusion peptides with different gold binding and silica binding parts. First, we have tested the binding capability of the fusion peptides using quartz crystal microbalance on gold surface and silica surface. Second, S1G1 hybrid peptide enabled assembly of gold nanoparticles on a silica surface was achieved. Finally, nanomaterial synthesis ability of the S1G1 peptide was presented by the formation of a silica film on a gold surface. In this study, we are presenting a hybrid peptide tool for nanohybrid assembly as a promising route for nanotechnology applications
Bio-nanohybrids of quantum dots and photoproteins facilitating strong nonradiative energy transfer
Cataloged from PDF version of article.Utilization of light is crucial for the life cycle of many organisms. Also, many organisms can create light by utilizing chemical energy emerged from biochemical reactions. Being the most important structural units of the organisms, proteins play a vital role in the formation of light in the form of bioluminescence. Such photoproteins have been isolated and identified for a long time; the exact mechanism of their bioluminescence is well established. Here we show a biomimetic approach to build a photoprotein based excitonic nanoassembly model system using colloidal quantum dots (QDs) for a new bioluminescent couple to be utilized in biotechnological and photonic applications. We concentrated on the formation mechanism of nanohybrids using a kinetic and thermodynamic approach. Finally we propose a biosensing scheme with an ON/OFF switch using the QD-GFP hybrid. The QD-GFP hybrid system promises strong exciton-exciton coupling between the protein and the quantum dot at a high efficiency level, possessing enhanced capabilities of light harvesting, which may bring new technological opportunities to mimic biophotonic events
Spatially Selective Assembly of Quantum Dot Light Emitters in an LED Using Engineered Peptides
Cataloged from PDF version of article.Semiconductor nanocrystal quantum dots are utilized in numerous applications in nano- and biotechnology. In device applications, where several different material components are involved, quantum dots typically need to be assembled at explicit locations for enhanced functionality. Conventional approaches cannot meet these requirements where assembly of nanocrystals is usually material-nonspecific, thereby limiting the control of their spatial distribution. Here we demonstrate directed self-assembly of quantum dot emitters at material-specific locations in a color-conversion LED containing several material components including a metal, a dielectric, and a semiconductor. We achieve a spatially selective immobilization of quantum dot emitters by using the unique material selectivity characteristics provided by the engineered solid-binding peptides as smart linkers. Peptide-decorated quantum dots exhibited several orders of magnitude higher photoluminescence compared to the control groups, thus, potentially opening up novel ways to advance these photonic platforms in applications ranging from chemical to biodetection. © 2011 American Chemical Society
La integración de los refugiados en el mercado laboral turco
La concesión en Turquía del derecho de acceso al trabajo formal a los refugiados sirios fue un primer paso hacia su integración económica, pero sigue habiendo retos. Con el apoyo de la comunidad internacional, el Gobierno turco está tomando medidas para superar algunos de ellos
An improvement of skin aging assessment by non-invasive laser speckle effect: A comparative texture analysis
Skin aging is a complex biological process that is yet to be successfully modelled as it depends on various internal and external factors. This work therefore investigates novel low-cost skin aging assessment technique and equipment by using robust analysis of textural features unified with a laser-speckle imaging method, which is found to be quite capable of detecting multi-layer cellular textural changes exhibited by the biological skin aging process. This study and low-cost product seem to be the first of its kind, which is expected to bring great benefit to both healthcare and cosmetic sectors
Twelve recommendations for advancing marine conservation in European and contiguous seas
Like most ocean regions today, the European and contiguous seas experience cumulative impacts from local human activities and global pressures. They are largely in poor environmental condition with deteriorating trends. Despite several success stories, European policies for marine conservation fall short of being effective. Acknowledging the challenges for marine conservation, a 4-year multi-national network, MarCons, supported collaborative marine conservation efforts to bridge the gap between science, management and policy, aiming to contribute in reversing present negative trends. By consolidating a large network of more than 100 scientists from 26 countries, and conducting a series of workshops over 4 years (2016–2020), MarCons analyzed challenges, opportunities and obstacles for advancing marine conservation in the European and contiguous seas. Here, we synthesize the major issues that emerged from this analysis and make 12 key recommendations for policy makers, marine managers, and researchers. To increase the effectiveness of marine conservation planning, we recommend (1) designing coherent networks of marine protected areas (MPAs) in the framework of marine spatial planning (MSP) and applying systematic conservation planning principles, including re-evaluation of existing management zones, (2) designing MPA networks within a broader transboundary planning framework, and (3) implementing integrated land-freshwater-sea approaches. To address inadequate or poorly informed management, we recommend (4) developing and implementing adaptive management plans in all sites of the Natura 2000 European conservation network and revising the Natura 2000 framework, (5) embedding and implementing cumulative effects assessments into a risk management process and making them operational, and (6) promoting actions to reach ‘good environmental status’ in all European waters. To account for global change in conservation planning and management, we further recommend (7) developing conservation strategies to address the impacts of global change, for example identifying climate-change refugia as high priority conservation areas, and (8) incorporating biological invasions in conservation plans and prioritizing management actions to control invasive species. Finally, to improve current practices that may compromise the effectiveness of conservation actions, we recommend (9) reinforcing the collection of high-quality open-access data, (10) improving mechanisms for public participation in MPA planning and management, (11) prioritizing conservation goals in full collaboration with stakeholders, and (12) addressing gender inequality in marine sciences and conservation
Multi-material specific, targeted self-assembly of nanocrystal emitters using genetically engineered peptides on optoelectronic microchips
[No abstract available
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