269 research outputs found
Myth and Magic in Early Byzantine Marriage Jewelry: The Persistence of Pre-Christian Traditions
The Constitutional Case for the Impeachability of Former Federal Officials: An Analysis of the Law, History, and Practice of Late Impeachment
Televised Executions and the Constitution: Recognizing a First Amendment Right of Access to State Executions
The effects of aging of scientists on their publication and citation patterns
The average age at which U.S. researchers get their first grant from NIH has
increased from 34.3 in 1970, to 41.7 in 2004. These data raise the crucial
question of the effects of aging on the scientific creativity and productivity
of researchers. Those who worry about the aging of scientists usually believe
that the younger they are the more creative and productive they will be. Using
a large population of 13,680 university professors in Quebec, we show that,
while scientific productivity rises sharply between 28 and 40, it increases at
a slower pace between 41 and 50 and stabilizes afterward until retirement for
the most active researchers. The average scientific impact per paper decreases
linearly until 50-55 years old, but the average number of papers in highly
cited journals and among highly cited papers rises continuously until
retirement. Our results clearly show for the first time the natural history of
the scientific productivity of scientists over their entire career and bring to
light the fact that researchers over 55 still contribute significantly to the
scientific community by producing high impact papers.Comment: 12 pages, 4 figure
An experimental study of low-level laser therapy in rat Achilles tendon injury
The aim of this controlled animal study was to investigate the effect of low-level laser therapy (LLLT) administered 30 min after injury to the Achilles tendon. The study animals comprised 16 Sprague Dawley male rats divided in two groups. The right Achilles tendons were injured by blunt trauma using a mini guillotine, and were treated with LLLT or placebo LLLT 30 min later. The injury and LLLT procedures were then repeated 15 hours later on the same tendon. One group received active LLLT (λ = 904 nm, 60 mW mean output power, 0.158 W/cm2 for 50 s, energy 3 J) and the other group received placebo LLLT 23 hours after LLLT. Ultrasonographic images were taken to measure the thickness of the right and left Achilles tendons. Animals were then killed, and all Achilles tendons were tested for ultimate tensile strength (UTS). All analyses were performed by blinded observers. There was a significant increase in tendon thickness in the active LLLT group when compared with the placebo group (p < 0.05) and there were no significant differences between the placebo and uninjured left tendons. There were no significant differences in UTS between laser-treated, placebo-treated and uninjured tendons. Laser irradiation of the Achilles tendon at 0.158 W/cm2 for 50 s (3 J) administered within the first 30 min after blunt trauma, and repeated after 15 h, appears to lead to edema of the tendon measured 23 hours after LLLT. The guillotine blunt trauma model seems suitable for inflicting tendon injury and measuring the effects of treatment on edema by ultrasonography and UTS. More studies are needed to further refine this model
Rise and Demise of Bioinformatics? Promise and Progress
The field of bioinformatics and computational biology has gone through a number of transformations during the past 15 years, establishing itself as a key component of new biology. This spectacular growth has been challenged by a number of disruptive changes in science and technology. Despite the apparent fatigue of the linguistic use of the term itself, bioinformatics has grown perhaps to a point beyond recognition. We explore both historical aspects and future trends and argue that as the field expands, key questions remain unanswered and acquire new meaning while at the same time the range of applications is widening to cover an ever increasing number of biological disciplines. These trends appear to be pointing to a redefinition of certain objectives, milestones, and possibly the field itself
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