Relating gravitational wave constraints from primordial nucleosynthesis, pulsar timing, laser interferometers, and the CMB: implications for the early universe

We derive a general master equation relating the gravitational-wave observables r and Omega_gw(f). Here r is the tensor-to-scalar ratio, constrained by cosmic-microwave-background (CMB) experiments; and Omega_gw(f) is the energy spectrum of primordial gravitational-waves, constrained e.g. by pulsar-timing measurements, laser-interferometer experiments, and Big Bang Nucleosynthesis (BBN). Differentiating the master equation yields a new expression for the tilt d(ln Omega_gw(f))/d(ln f). The relationship between r and Omega_gw(f) depends sensitively on the uncertain physics of the early universe, and we show that this uncertainty may be encapsulated (in a model-independent way) by two quantities: w_hat(f) and nt_hat(f), where nt_hat(f) is a certain logarithmic average over nt(k) (the primordial tensor spectral index); and w_hat(f) is a certain logarithmic average over w_tilde(a) (the effective equation-of-state in the early universe, after horizon re-entry). Here the effective equation-of-state parameter w_tilde(a) is a combination of the ordinary equation-of-state parameter w(a) and the bulk viscosity zeta(a). Thus, by comparing constraints on r and Omega_gw(f), one can obtain (remarkably tight) constraints in the [w_hat(f), nt_hat(f)] plane. In particular, this is the best way to constrain (or detect) the presence of a ``stiff'' energy component (with w > 1/3) in the early universe, prior to BBN. Finally, although most of our analysis does not assume inflation, we point out that if CMB experiments detect a non-zero value for r, then we will immediately obtain (as a free by-product) a new upper bound w_hat < 0.55 on the logarithmically averaged effective equation-of-state parameter during the ``primordial dark age'' between the end of inflation and the start of BBN.Comment: v1: 12 + 6 pages (main text + appendices), 7 figures; v2: fonts fixed in figure

Detecting relic gravitational radiation from string cosmology with LIGO

A characteristic spectrum of relic gravitational radiation is produced by a period of ``stringy inflation" in the early universe. This spectrum is unusual, because the energy-density rises rapidly with frequency. We show that correlation experiments with the two gravitational wave detectors being built for the Laser Interferometric Gravitational Observatory (LIGO) could detect this relic radiation, for certain ranges of the parameters that characterize the underlying string cosmology model.Comment: 6 pages, 5 eps figures, Revte

Relic Gravitational Waves from String Cosmology

A large class of string-cosmology backgrounds leads to a spectrum of relic stochastic gravitational waves, strongly tilted towards high frequencies, and characterized by two basic parameters of the cosmological model. We estimate the required sensitivity for detection of the predicted gravitational radiation and show that a region of our parameter space is within reach for some of the planned gravitational-wave detectors.Comment: 14 pages, latex, 2 figures included as epsf file

Peak and end point of the relic graviton background in string cosmology

Using general arguments we determine the allowed region for the end point frequency and the peak energy density of the stochastic background of gravity waves expected in string cosmology. We provide an accurate estimate of the minimal experimental sensitivity required to detect a signal in the Hz to GHz range.Comment: 11 pages, LATEX, one figure included using eps. A complete collection of papers and references on the pre-big-bang scenario in string cosmology is available at http://www.to.infn.it/teorici/gasperini

Thermal history of the plasma and high-frequency gravitons

Possible deviations from a radiation-dominated evolution, occurring prior the synthesis of light nuclei, impacted on the spectral energy density of high-frequency gravitons. For a systematic scrutiny of this situation, the $\Lambda$CDM paradigm must be complemented by (at least two) physical parameters describing, respectively, a threshold frequency and a slope. The supplementary frequency scale sets the lower border of a high-frequency domain where the spectral energy grows with a slope which depends, predominantly, upon the total sound speed of the plasma right after inflation. While the infra-red region of the graviton energy spectrum is nearly scale-invariant, the expected signals for typical frequencies larger than 0.01 nHz are hereby analyzed in a model-independent framework by requiring that the total sound speed of the post-inflationary plasma be smaller than the speed of light. Current (e.g. low-frequency) upper limits on the tensor power spectra (determined from the combined analysis of the three large-scale data sets) are shown to be compatible with a detectable signal in the frequency range of wide-band interferometers. In the present context, the scrutiny of the early evolution of the sound speed of the plasma can then be mapped onto a reliable strategy of parameter extraction including not only the well established cosmological observables but also the forthcoming data from wide band interferometers.Comment: 47 pages, 31 included figures, to appear in Classical and Quantum Gravit

Scalar and Tensor Inhomogeneities from Dimensional Decoupling

We discuss some perturbative techniques suitable for the gauge-invariant treatment of the scalar and tensor inhomogeneities of an anisotropic and homogeneous background geometry whose spatial section naturally decomposes into the direct product of two maximally symmetric Eucledian manifolds, describing a general situation of dimensional decoupling in which $d$ external dimensions evolve (in conformal time) with scale factor $a(\eta)$ and $n$ internal dimensions evolve with scale factor $b(\eta)$. We analyze the growing mode problem which typically arises in contracting backgrounds and we focus our attention on the situation where the amplitude of the fluctuations not only depends on the external space-time but also on the internal spatial coordinates. In order to illustrate the possible relevance of this analysis we compute the gravity waves spectrum produced in some highly simplified model of cosmological evolution and we find that the spectral amplitude, whose magnitude can be constrained by the usual bounds applied to the stochastic gravity waves backgrounds, depends on the curvature scale at which the compactification occurs and also on the typical frequency of the internal excitations.Comment: 31 pages, Latex, DAMTP 96-92, UCM 96-04, to appear in Phys. Rev. D 55 (1997

Portuguese Ministers, 1851-1999: Social Background and Paths to Power

Disponível em: http://193.136.113.6/Opac/Pages/Search/Results.aspx?SearchText=UID=bb8aa8d5-c6b6-466a-81bb-fe8a67693cee&DataBase=10449_UNLFCSHThis paper provides an empirical analysis of the impact of regime changes in the composition and patterns of recruitment of the Portuguese ministerial elite throughout the last 150 years. The ‘out-of-type’, violent nature of most regime transformations accounts for the purges in and the extensive replacements of the political personnel, namely of the uppermost officeholders. In the case of Cabinet members, such discontinuities did not imply, however, radical changes in their social profile. Although there were some significant variations, a series of salient characteristics have persisted over time. The typical Portuguese minister is a male in his midforties, of middle-class origin and predominantly urban-born, highly educated and with a state servant background. The two main occupational contingents have been university professors - except for the First Republic (1910-26) - and the military, the latter having only recently been eclipsed with the consolidation of contemporary democracy. As regards career pathways, the most striking feature is the secular trend for the declining role of parliamentary experience, which the democratic regime did not clearly reverse. In this period, a technocratic background rather than political experience has been indeed the privileged credential for a significant proportion of minister

Stochastic backgrounds of relic gravitons: a theoretical appraisal

Stochastic backgrounds or relic gravitons, if ever detected, will constitute a prima facie evidence of physical processes taking place during the earliest stages of the evolution of the plasma. The essentials of the stochastic backgrounds of relic gravitons are hereby introduced and reviewed. The pivotal observables customarily employed to infer the properties of the relic gravitons are discussed both in the framework of the $\Lambda$CDM paradigm as well as in neighboring contexts. The complementarity between experiments measuring the polarization of the Cosmic Microwave Background (such as, for instance, WMAP, Capmap, Quad, Cbi, just to mention a few) and wide band interferometers (e.g. Virgo, Ligo, Geo, Tama) is emphasized. While the analysis of the microwave sky strongly constrains the low-frequency tail of the relic graviton spectrum, wide-band detectors are sensitive to much higher frequencies where the spectral energy density depends chiefly upon the (poorly known) rate of post-inflationary expansion.Comment: 94 pages, 32 figure

Diretriz sobre Diagnóstico e Tratamento da Cardiomiopatia Hipertrófica – 2024

Hypertrophic cardiomyopathy (HCM) is a form of genetically caused heart muscle disease, characterized by the thickening of the ventricular walls. Diagnosis requires detection through imaging methods (Echocardiogram or Cardiac Magnetic Resonance) showing any segment of the left ventricular wall with a thickness &gt; 15 mm, without any other probable cause. Genetic analysis allows the identification of mutations in genes encoding different structures of the sarcomere responsible for the development of HCM in about 60% of cases, enabling screening of family members and genetic counseling, as an important part of patient and family management. Several concepts about HCM have recently been reviewed, including its prevalence of 1 in 250 individuals, hence not a rare but rather underdiagnosed disease. The vast majority of patients are asymptomatic. In symptomatic cases, obstruction of the left ventricular outflow tract (LVOT) is the primary disorder responsible for symptoms, and its presence should be investigated in all cases. In those where resting echocardiogram or Valsalva maneuver does not detect significant intraventricular gradient (&gt; 30 mmHg), they should undergo stress echocardiography to detect LVOT obstruction. Patients with limiting symptoms and severe LVOT obstruction, refractory to beta-blockers and verapamil, should receive septal reduction therapies or use new drugs inhibiting cardiac myosin. Finally, appropriately identified patients at increased risk of sudden death may receive prophylactic measure with implantable cardioverter-defibrillator (ICD) implantation.La miocardiopatía hipertrófica (MCH) es una forma de enfermedad cardíaca de origen genético, caracterizada por el engrosamiento de las paredes ventriculares. El diagnóstico requiere la detección mediante métodos de imagen (Ecocardiograma o Resonancia Magnética Cardíaca) que muestren algún segmento de la pared ventricular izquierda con un grosor &gt; 15 mm, sin otra causa probable. El análisis genético permite identificar mutaciones en genes que codifican diferentes estructuras del sarcómero responsables del desarrollo de la MCH en aproximadamente el 60% de los casos, lo que permite el tamizaje de familiares y el asesoramiento genético, como parte importante del manejo de pacientes y familiares. Varios conceptos sobre la MCH han sido revisados recientemente, incluida su prevalencia de 1 entre 250 individuos, por lo tanto, no es una enfermedad rara, sino subdiagnosticada. La gran mayoría de los pacientes son asintomáticos. En los casos sintomáticos, la obstrucción del tracto de salida ventricular izquierdo (TSVI) es el trastorno principal responsable de los síntomas, y su presencia debe investigarse en todos los casos. En aquellos en los que el ecocardiograma en reposo o la maniobra de Valsalva no detecta un gradiente intraventricular significativo (&gt; 30 mmHg), deben someterse a ecocardiografía de esfuerzo para detectar la obstrucción del TSVI. Los pacientes con síntomas limitantes y obstrucción grave del TSVI, refractarios al uso de betabloqueantes y verapamilo, deben recibir terapias de reducción septal o usar nuevos medicamentos inhibidores de la miosina cardíaca. Finalmente, los pacientes adecuadamente identificados con un riesgo aumentado de muerte súbita pueden recibir medidas profilácticas con el implante de un cardioversor-desfibrilador implantable (CDI).A cardiomiopatia hipertrófica (CMH) é uma forma de doença do músculo cardíaco de causa genética, caracterizada pela hipertrofia das paredes ventriculares. O diagnóstico requer detecção por métodos de imagem (Ecocardiograma ou Ressonância Magnética Cardíaca) de qualquer segmento da parede do ventrículo esquerdo com espessura &gt; 15 mm, sem outra causa provável. A análise genética permite identificar mutações de genes codificantes de diferentes estruturas do sarcômero responsáveis pelo desenvolvimento da CMH em cerca de 60% dos casos, permitindo o rastreio de familiares e aconselhamento genético, como parte importante do manejo dos pacientes e familiares. Vários conceitos sobre a CMH foram recentemente revistos, incluindo sua prevalência de 1 em 250 indivíduos, não sendo, portanto, uma doença rara, mas subdiagnosticada. A vasta maioria dos pacientes é assintomática. Naqueles sintomáticos, a obstrução do trato de saída do ventrículo esquerdo (OTSVE) é o principal distúrbio responsável pelos sintomas, devendo-se investigar a sua presença em todos os casos. Naqueles em que o ecocardiograma em repouso ou com Manobra de Valsalva não detecta gradiente intraventricular significativo (&gt; 30 mmHg), devem ser submetidos à ecocardiografia com esforço físico para detecção da OTSVE.&nbsp;&nbsp; Pacientes com sintomas limitantes e grave OTSVE, refratários ao uso de betabloqueadores e verapamil, devem receber terapias de redução septal ou uso de novas drogas inibidoras da miosina cardíaca. Por fim, os pacientes adequadamente identificados com risco aumentado de morta súbita podem receber medida profilática com implante de cardiodesfibrilador implantável (CDI)

Coupled Approach for Reliability Study of Fully Self Aligned SiGe:C 250GHz HBTs.

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