593 research outputs found
Corrosion Control in Industry
The economic development of any region, state or country, depends not only on its natural reâ sources and productive activities, but also on the infrastructure that account for the exploitaâ tion, processing and marketing of goods. Irrigation systems, roads, bridges, airports, maritime, land and air transport, school buildings, offices and housing, industrial installations are affectâ ed by corrosion and therefore susceptible to deterioration and degradation processes
First direct measurements of behavioural responses by Cuvier's beaked whales to mid-frequency active sonar
Most marine mammal strandings coincident with naval sonar exercises have involved Cuvier's beaked whales (Ziphius cavirostris). We recorded animal movement and acoustic data on two tagged Ziphius and obtained the first direct measurements of behavioural responses of this species to mid-frequency active (MFA) sonar signals. Each recording included a 30-min playback (one 1.6-s simulated MFA sonar signal repeated every 25 s); one whale was also incidentally exposed to MFA sonar from distant naval exercises. Whales responded strongly to playbacks at low received levels (RLs; 89–127 dB re 1 µPa): after ceasing normal fluking and echolocation, they swam rapidly, silently away, extending both dive duration and subsequent non-foraging interval. Distant sonar exercises (78–106 dB re 1 µPa) did not elicit such responses, suggesting that context may moderate reactions. The observed responses to playback occurred at RLs well below current regulatory thresholds; equivalent responses to operational sonars could elevate stranding risk and reduce foraging efficiency.Publisher PDFPeer reviewe
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Aspiration therapy for the treatment of obesity: 4-year results of a multicenter randomized controlled trial.
BackgroundThe AspireAssist is the first Food and Drug Administration-approved endoluminal device indicated for treatment of class II and III obesity.ObjectivesWe earlier reported 1-year results of the PATHWAY study. Here, we report 4-year outcomes.SettingUnited States-based, 10-center, randomized controlled trial involving 171 participants with the treatment arm receiving Aspiration Therapy (AT) plus Lifestyle Therapy and the control arm receiving Lifestyle Therapy (2:1 randomization).MethodsAT participants were permitted to continue in the study for an additional year up to a maximum of 5 years providing they maintained at least 10% total weight loss (TWL) from baseline at each year end. For AT participants who continued the study, 5 medical monitoring visits were provided at weeks 60, 68, 76, 90, and 104 and thereafter once every 13 weeks up to week 260. Exclusion criteria were a history of eating disorder or evidence of eating disorder on a validated questionnaire. Follow-up weight, quality of life, and co-morbidities were compared with the baseline levels. In addition, rates of serious adverse event, persistent fistula, withdrawal, and A-tube replacement were reported. All analyses were performed using a per-protocol analysis.ResultsOf the 82 AT participants who completed 1 year, 58 continued to this phase of the trial. Mean baseline body mass index of these 58 patients was 41.6 ± 4.5 kg/m2. At the end of first year (at the beginning of the follow-up study), these 58 patients had a body mass index of 34.1 ± 5.4 kg/m2 and had achieved an 18.3 ± 8.0% TWL. On a per protocol basis, patients experienced 14.2%, 15.3%, 16.6%, and 18.7% TWL at 1, 2, 3, and 4 years, respectively (P < .01 for all). Forty of 58 patients (69%) achieved at least 10% TWL at 4 years or at time of study withdrawal. Improvements in quality of life scores and select cardiometabolic parameters were also maintained through 4 years. There were 2 serious adverse events reported in the second through fourth years, both of which resolved with removal or replacement of the A tube. Two persistent fistulas required surgical repair, representing approximately 2% of all tube removals. There were no clinically significant metabolic or electrolytes disorders observed, nor any evidence for development of any eating disorders.ConclusionsThe results of this midterm study have shown that AT is a safe, effective, and durable weight loss alternative for people with class II and III obesity and who are willing to commit to using the therapy and adhere to adjustments in eating behavior
Reducing recurrent care proceedings: initial evidence from new interventions
The English family justice system faces a crisis of recurrence. As many as one in four birth mothers involved in public law care proceedings in English family courts are likely to reappear in a subsequent set of proceedings within seven years. These mothers are involved in up to one-third of total care applications, as they are – by definition – linked to more than one child . Few birth mothers experiencing the removal of a child to care are offered any follow-up support, despite often facing multiple challenges including poverty, addiction, domestic violence and mental health problems. Since 2011, however, a number of new services have been established to begin to address their unmet needs. This article summarises the findings of the first academic-led evaluation of two of these initiatives. Presenting evidence from a mixed-methods evaluative study, it concludes that the new services were able to foster relationships that ‘worked’ in reducing recurrent proceedings. None of the women engaging with the services went on to experience what could be described as a ‘rapid repeat pregnancy’ within the evaluation window. Just as significantly, a number of clients reported some improvement in their psychological functioning, and the practitioners involved reported positively on their experience of delivering and managing innovative services. The article closes with a discussion of the challenges of evaluating personalised, strengths-based interventions and the possibilities of evidencing empowerment in these cases
Antiperiodic dynamical 6-vertex model I: Complete spectrum by SOV, matrix elements of the identity on separate states and connections to the periodic 8-vertex model
The spin-1/2 highest weight representations of the dynamical 6-vertex and the
standard 8-vertex Yang-Baxter algebra on a finite chain are considered in this
paper. For the antiperiodic dynamical 6-vertex transfer matrix defined on
chains with an odd number of sites, we adapt the Sklyanin's quantum separation
of variable (SOV) method and explicitly construct SOV representations from the
original space of representations. We provide the complete characterization of
eigenvalues and eigenstates proving also the simplicity of its spectrum.
Moreover, we characterize the matrix elements of the identity on separated
states by determinant formulae. The matrices entering in these determinants
have elements given by sums over the SOV spectrum of the product of the
coefficients of separate states. This SOV analysis is not reduced to the case
of the elliptic roots of unit and the results here derived define the required
setup to extend to the dynamical 6-vertex model the approach recently developed
in [1]-[5] to compute the form factors of the local operators in the SOV
framework, these results will be presented in a future publication. For the
periodic 8-vertex transfer matrix, we prove that its eigenvalues have to
satisfy a fixed system of equations. In the case of a chain with an odd number
of sites, this system of equations is the same entering in the SOV
characterization of the antiperiodic dynamical 6-vertex transfer matrix
spectrum. This implies that the set of the periodic 8-vertex eigenvalues is
contained in the set of the antiperiodic dynamical 6-vertex eigenvalues. A
criterion is introduced to find simultaneous eigenvalues of these two transfer
matrices and associate to any of such eigenvalues one nonzero eigenstate of the
periodic 8-vertex transfer matrix by using the SOV results. Moreover, a
preliminary discussion on the degeneracy of the periodic 8-vertex spectrum is
also presented.Comment: 36 pages, main modifications in section 3 and one appendix added, no
result modified for the dynamical 6-vertex transfer matrix spectrum and the
matrix elements of identity on separate states for chains with an odd number
of site
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.
OBJECTIVE: To provide an update to "Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012." DESIGN: A consensus committee of 55 international experts representing 25 international organizations was convened. Nominal groups were assembled at key international meetings (for those committee members attending the conference). A formal conflict-of-interest (COI) policy was developed at the onset of the process and enforced throughout. A stand-alone meeting was held for all panel members in December 2015. Teleconferences and electronic-based discussion among subgroups and among the entire committee served as an integral part of the development. METHODS: The panel consisted of five sections: hemodynamics, infection, adjunctive therapies, metabolic, and ventilation. Population, intervention, comparison, and outcomes (PICO) questions were reviewed and updated as needed, and evidence profiles were generated. Each subgroup generated a list of questions, searched for best available evidence, and then followed the principles of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system to assess the quality of evidence from high to very low, and to formulate recommendations as strong or weak, or best practice statement when applicable. RESULTS: The Surviving Sepsis Guideline panel provided 93 statements on early management and resuscitation of patients with sepsis or septic shock. Overall, 32 were strong recommendations, 39 were weak recommendations, and 18 were best-practice statements. No recommendation was provided for four questions. CONCLUSIONS: Substantial agreement exists among a large cohort of international experts regarding many strong recommendations for the best care of patients with sepsis. Although a significant number of aspects of care have relatively weak support, evidence-based recommendations regarding the acute management of sepsis and septic shock are the foundation of improved outcomes for these critically ill patients with high mortality
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Using accelerometers to determine the calling behavior of tagged baleen whales
Low-frequency acoustic signals generated by baleen whales can
propagate over vast distances, making the assignment of calls to
specific individuals problematic. Here, we report the novel use of
acoustic recording tags equipped with high-resolution accelerometers
to detect vibrations from the surface of two tagged fin whales that
directly match the timing of recorded acoustic signals. A tag deployed
on a buoy in the vicinity of calling fin whales and a recording from a
tag that had just fallen off a whale were able to detect calls
acoustically but did not record corresponding accelerometer signals
that were measured on calling individuals. Across the hundreds of
calls measured on two tagged fin whales, the accelerometer
response was generally anisotropic across all three axes, appeared
to depend on tag placement and increased with the level of received
sound. These data demonstrate that high-sample rate accelerometry
can provide important insights into the acoustic behavior of baleen
whales that communicate at low frequencies. This method helps
identify vocalizing whales, which in turn enables the quantification of
call rates, a fundamental component of models used to estimate
baleen whale abundance and distribution from passive acoustic
monitoring.Keywords: Whale, Acceleration, Acoustic
Towards a ‘Long View’: Historical Perspectives on the Scaling and Replication of Social Ventures
Social ventures are now widely regarded as playing an essential role in addressing persistent and pervasive societal challenges. This insight has prompted an active search for readily-scaleable and replicable business models. However, relatively little consideration has been given to the longer-term growth and performance of these hybrid organizational forms. This paper examines how historically-informed research might enhance our understanding of growth processes. It considers the conceptualization of organizational growth in social ventures and the relevance of prevailing constructs. The explanatory potential of ‘long view’ approaches examined by applying three constructs, opportunity recognition, entrepreneurial adjustment, and institutional structure, in a comparative historical analysis of two British social ventures
Participatory action research in two communities in Bolivia and the United States
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66665/2/10.1177_002087289203500214.pd
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