Hydrographic data from the OPTOMA Program: OPTOMA11, 5-June-5 August, 1984

The six cruises and one aircraft flight comprising OPTOMA11 were undertaken in June, July and August 1984 to sample two subdomains of the California Current. This report presents the hydrographic data, acquired by XBT, AXBT and CTD casts, from the cruises and the flight.Research project "Ocean Prediction Through Observations, Modeling and Analysis" sponsored by the Physical Oceanography Program of the Office of Naval Research under Program Element 61153N.http://archive.org/details/hydrographicdata011wittN000148WR24051NAApproved for public release; distribution is unlimited

Measurement of ϒ production in pp collisions at √s = 2.76 TeV

The production of ϒ(1S), ϒ(2S) and ϒ(3S) mesons decaying into the dimuon final state is studied with the LHCb detector using a data sample corresponding to an integrated luminosity of 3.3 pb−1 collected in proton–proton collisions at a centre-of-mass energy of √s = 2.76 TeV. The differential production cross-sections times dimuon branching fractions are measured as functions of the ϒ transverse momentum and rapidity, over the ranges pT < 15 GeV/c and 2.0 < y < 4.5. The total cross-sections in this kinematic region, assuming unpolarised production, are measured to be σ (pp → ϒ(1S)X) × B ϒ(1S)→μ+μ− = 1.111 ± 0.043 ± 0.044 nb, σ (pp → ϒ(2S)X) × B ϒ(2S)→μ+μ− = 0.264 ± 0.023 ± 0.011 nb, σ (pp → ϒ(3S)X) × B ϒ(3S)→μ+μ− = 0.159 ± 0.020 ± 0.007 nb, where the first uncertainty is statistical and the second systematic

Auditing environmental impact statements using information held in public registers of environmental information

SIGLEAvailable from British Library Document Supply Centre-DSC:9349.83402(OBU-SP-WP--165) / BLDSC - British Library Document Supply CentreGBUnited Kingdo

Hydrographic data from the slope waters off central California : 26 November 1978 - 26 June 1980 /

This report presents hydrographic data acquired by STD casts from the period November, 1978 through June, 1980 from the slope waters off central California.Minerals Management Service, Department of the Interiorhttp://archive.org/details/hydrographicdata010birdNAApproved for public release; distribution is unlimited

R-loops and PRC1 repress Polycomb-target genes in mouse embryonic stem cells

Experiment type: Genome binding/occupancy profiling by high throughput sequencing. Overall design: Genome-wide distribution of PRC2 subunits EZH2 and SUZ12 in mESC in presence or absence of R-loops.R-loops are three-stranded nucleic acid structures that form naturally during transcription, especially over unmethylated CpG-rich promoters. In mESC, such promoters of developmental regulator genes are occupied by the Polycomb-repressor complexes PRC1 and PRC2. Here we have explored the possibility that R-loops form over Polycomb-repressed genes and play a role in their transcriptional silencing. Using single gene and genome-wide analyses, we show that R-loops form at a specific subset of PRC-target genes and contribute to Polycomb occupancy on chromatin. Removal of R-loops leads to an up-regulation of nascent and processed transcripts and the appearance of the elongating form of RNA polymerase II. In contrast, removal of PRC2 does not influence R-loop formation, transcriptional repression and PRC1 recruitment. We finally show that R-loops and PRC1 can repress Polycomb-target genes in the absence of PRC2. Our results uncover an unanticipated synergy between R-loops and PRC1 in Polycomb repression mechanisms.Skourti-Stathaki K, Torlai Triglia E, Warburton M, Voigt P et al. R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes. Mol Cell 2019 Mar 7;73(5):930-945.e4. PMID: 3070970