1,351 research outputs found
A new model for hemoglobin ingestion and transport by the human malaria parasite Plasmodium falciparum.
The current model for hemoglobin ingestion and transport by intraerythrocytic Plasmodium falciparum malaria parasites shares similarities with endocytosis. However, the model is largely hypothetical, and the mechanisms responsible for the ingestion and transport of host cell hemoglobin to the lysosome-like food vacuole (FV) of the parasite are poorly understood. Because actin dynamics play key roles in vesicle formation and transport in endocytosis, we used the actin-perturbing agents jasplakinolide and cytochalasin D to investigate the role of parasite actin in hemoglobin ingestion and transport to the FV. In addition, we tested the current hemoglobin trafficking model through extensive analysis of serial thin sections of parasitized erythrocytes (PE) by electron microscopy. We find that actin dynamics play multiple, important roles in the hemoglobin transport pathway, and that hemoglobin delivery to the FV via the cytostomes might be required for parasite survival. Evidence is provided for a new model, in which hemoglobin transport to the FV occurs by a vesicle-independent process
Continuum and Emission-Line Properties of Broad Absorption Line Quasars
We investigate the continuum and emission-line properties of 224 broad
absorption line quasars (BALQSOs) with 0.9<z<4.4 drawn from the Sloan Digital
Sky Survey (SDSS) Early Data Release (EDR), which contains 3814 bona fide
quasars. We find that low-ionization BALQSOs (LoBALs) are significantly
reddened as compared to normal quasars, in agreement with previous work.
High-ionization BALQSOs (HiBALs) are also more reddened than the average
nonBALQSO. Assuming SMC-like dust reddening at the quasar redshift, the amount
of reddening needed to explain HiBALs is E(B-V)~0.023 and LoBALs is
E(B-V)~0.077 (compared to the ensemble average of the entire quasar sample). We
find that there are differences in the emission-line properties between the
average HiBAL, LoBAL, and nonBAL quasar. These differences, along with
differences in the absorption line troughs, may be related to intrinsic quasar
properties such as the slope of the intrinsic (unreddened) continuum; more
extreme absorption properties are correlated with bluer intrinsic continua.
Despite the differences among BALQSO sub-types and nonBALQSOs, BALQSOs appear
to be drawn from the same parent population as nonBALQSOs when both are
selected by their UV/optical properties. We find that the overall fraction of
traditionally defined BALQSOs, after correcting for color-dependent selection
effects due to different SEDs of BALQSO and nonBALQSOs, is 13.4+/-1.2% and
shows no significant redshift dependence for 1.7<z<3.45. After a rough
completeness correction for the effects of dust extinction, we find that
approximately one in every six quasars is a BALQSO.Comment: 35 pages, 11 figures (1 color), 1 table; accepted by A
Emergence of microfrequency comb via limit cycles in dissipatively coupled condensates
Self-sustained oscillations, limit cycles, are a fundamental phenomenon unique to nonlinear dynamic systems of high-dimensional phase space. They enable understanding of a wide range of cyclic processes in natural, social and engineering systems. Here we show that limit cycles form in coupled polariton cavities following the breaking of Josephson coupling, leading to frequency-comb emission. The limit cycles and destruction of Josephson coupling both appear due to interplay between strong polariton-polariton interaction and a dissipative contribution to the cavity coupling. The resulting nonlinear dynamics of the condensates is characterized by asymmetric population distribution and nontrivial average phase difference between the two condensates, and by time-periodic modulation of their amplitudes and phases. The latter is manifested by coherent emission of new equidistant frequency components. The emission spectrum resembles that of a micro-frequency comb, but originates from a fundamentally different mechanism than that of existing frequency combs. It allows non-resonant excitation with a power input much below the conventional semiconductor laser threshold. The comb line spacing is determined by the interaction and coupling strengths, and is adjustable up to multi-terahertz frequency. The work establishes coupled polariton cavities as an experimental platform for rich nonlinear dynamic phenomena.PostprintPeer reviewe
Evidence for Reionization at z ~ 6: Detection of a Gunn-Peterson Trough in a z=6.28 Quasar
We present moderate resolution Keck spectroscopy of quasars at z=5.82, 5.99
and 6.28, discovered by the Sloan Digital Sky Survey (SDSS). We find that the
Ly Alpha absorption in the spectra of these quasars evolves strongly with
redshift. To z~5.7, the Ly Alpha absorption evolves as expected from an
extrapolation from lower redshifts. However, in the highest redshift object,
SDSSp J103027.10+052455.0 (z=6.28), the average transmitted flux is
0.0038+-0.0026 times that of the continuum level over 8450 A < lambda < 8710 A
(5.95<z(abs)<6.16), consistent with zero flux. Thus the flux level drops by a
factor of >150, and is consistent with zero flux in the Ly Alpha forest region
immediately blueward of the Ly Alpha emission line, compared with a drop by a
factor of ~10 at z(abs)~5.3. A similar break is seen at Ly Beta; because of the
decreased oscillator strength of this transition, this allows us to put a
considerably stronger limit, tau(eff) > 20, on the optical depth to Ly Alpha
absorption at z=6.
This is a clear detection of a complete Gunn-Peterson trough, caused by
neutral hydrogen in the intergalactic medium. Even a small neutral hydrogen
fraction in the intergalactic medium would result in an undetectable flux in
the Ly Alpha forest region. Therefore, the existence of the Gunn-Peterson
trough by itself does not indicate that the quasar is observed prior to the
reionization epoch. However, the fast evolution of the mean absorption in these
high-redshift quasars suggests that the mean ionizing background along the line
of sight to this quasar has declined significantly from z~5 to 6, and the
universe is approaching the reionization epoch at z~6.Comment: Revised version (2001 Sep 4) accepted by the Astronomical Journal
(minor changes
Five High-Redshift Quasars Discovered in Commissioning Imaging Data of the Sloan Digital Sky Survey
We report the discovery of five quasars with redshifts of 4.67 - 5.27 and
z'-band magnitudes of 19.5-20.7 M_B ~ -27. All were originally selected as
distant quasar candidates in optical/near-infrared photometry from the Sloan
Digital Sky Survey (SDSS), and most were confirmed as probable high-redshift
quasars by supplementing the SDSS data with J and K measurements. The quasars
possess strong, broad Lyman-alpha emission lines, with the characteristic sharp
cutoff on the blue side produced by Lyman-alpha forest absorption. Three
quasars contain strong, broad absorption features, and one of them exhibits
very strong N V emission. The amount of absorption produced by the Lyman-alpha
forest increases toward higher redshift, and that in the z=5.27 object (D_A ~
0.7) is consistent with a smooth extrapolation of the absorption seen in lower
redshift quasars. The high luminosity of these objects relative to most other
known objects at z >~ 5 makes them potentially valuable as probes of early
quasar properties and of the intervening intergalactic medium.Comment: 13 pages in LaTex format, two postscirpt figures. Submitted to the
Astronomical Journa
Testing the Asteroseismic Mass Scale Using Metal-Poor Stars Characterized with APOGEE and Kepler
Fundamental stellar properties, such as mass, radius, and age, can be
inferred using asteroseismology. Cool stars with convective envelopes have
turbulent motions that can stochastically drive and damp pulsations. The
properties of the oscillation frequency power spectrum can be tied to mass and
radius through solar-scaled asteroseismic relations. Stellar properties derived
using these scaling relations need verification over a range of metallicities.
Because the age and mass of halo stars are well-constrained by astrophysical
priors, they provide an independent, empirical check on asteroseismic mass
estimates in the low-metallicity regime. We identify nine metal-poor red giants
(including six stars that are kinematically associated with the halo) from a
sample observed by both the Kepler space telescope and the Sloan Digital Sky
Survey-III APOGEE spectroscopic survey. We compare masses inferred using
asteroseismology to those expected for halo and thick-disk stars. Although our
sample is small, standard scaling relations, combined with asteroseismic
parameters from the APOKASC Catalog, produce masses that are systematically
higher (=0.17+/-0.05 Msun) than astrophysical expectations. The
magnitude of the mass discrepancy is reduced by known theoretical corrections
to the measured large frequency separation scaling relationship. Using
alternative methods for measuring asteroseismic parameters induces systematic
shifts at the 0.04 Msun level. We also compare published asteroseismic analyses
with scaling relationship masses to examine the impact of using the frequency
of maximum power as a constraint. Upcoming APOKASC observations will provide a
larger sample of ~100 metal-poor stars, important for detailed asteroseismic
characterization of Galactic stellar populations.Comment: 4 figures; 1 table. Accepted to ApJ
High-Redshift Quasars Found in Sloan Digital Sky Survey Commissioning Data II: The Spring Equatorial Stripe
This is the second paper in a series aimed at finding high-redshift quasars
from five-color (u'g'r'i'z') imaging data taken along the Celestial Equator by
the Sloan Digital Sky Survey (SDSS) during its commissioning phase. In this
paper, we present 22 high-redshift quasars (z>3.6) discovered from ~250 deg^2
of data in the spring Equatorial Stripe, plus photometry for two previously
known high-redshift quasars in the same region of sky. Our success rate of
identifying high-redshift quasars is 68%. Five of the newly discovered quasars
have redshifts higher than 4.6 (z=4.62, 4.69, 4.70, 4.92 and 5.03). All the
quasars have i* < 20.2 with absolute magnitude -28.8 < M_B < -26.1 (h=0.5,
q_0=0.5). Several of the quasars show unusual emission and absorption features
in their spectra, including an object at z=4.62 without detectable emission
lines, and a Broad Absorption Line (BAL) quasar at z=4.92.Comment: 28 pages, AJ in press (Jan 2000), final version with minor changes;
high resolution finding charts available at
http://www.astro.princeton.edu/~fan/paper/qso2.htm
High-Redshift Quasars Found in Sloan Digital Sky Survey Commissioning Data IV: Luminosity Function from the Fall Equatorial Stripe Sampl
This is the fourth paper in a series aimed at finding high-redshift quasars
from five-color imaging data taken along the Celestial Equator by the SDSS.
during its commissioning phase. In this paper, we use the color-selected sample
of 39 luminous high-redshift quasars presented in Paper III to derive the
evolution of the quasar luminosity function over the range of 3.6<z<5.0, and
-27.5<M_1450<-25.5 (Omega=1, H_0=50 km s^-1 Mpc^-1). We use the selection
function derived in Paper III to correct for sample incompleteness. The
luminosity function is estimated using three different methods: (1) the 1/V_a
estimator; (2) a maximum likelihood solution, assuming that the density of
quasars depends exponentially on redshift and as a power law in luminosity and
(3) Lynden-Bell's non-parametric C^- estimator. All three methods give
consistent results. The luminous quasar density decreases by a factor of ~ 6
from z=3.5 to z=5.0, consistent with the decline seen from several previous
optical surveys at z<4.5. The luminosity function follows psi(L) ~ L^{-2.5} for
z~4 at the bright end, significantly flatter than the bright end luminosity
function psi(L) \propto L^{-3.5} found in previous studies for z<3, suggesting
that the shape of the quasar luminosity function evolves with redshift as well,
and that the quasar evolution from z=2 to 5 cannot be described as pure
luminosity evolution. Possible selection biases and the effect of dust
extinction on the redshift evolution of the quasar density are also discussed.Comment: AJ accepted, with minor change
Early-type galaxies in the SDSS. I. The sample
A sample of nearly 9000 early-type galaxies, in the redshift range 0.01 < z <
0.3, was selected from the Sloan Digital Sky Survey using morphological and
spectral criteria. This paper describes how the sample was selected, presents
examples of images and seeing corrected fits to the observed surface brightness
profiles, describes our method for estimating K-corrections, and shows that the
SDSS spectra are of sufficiently high quality to measure velocity dispersions
accurately. It also provides catalogs of the measured photometric and
spectroscopic parameters. In related papers, these data are used to study how
early-type galaxy observables, including luminosity, effective radius, surface
brightness, color, and velocity dispersion, are correlated with one another.Comment: 63 pages, 21 figures. Accepted by AJ (scheduled for April 2003). This
paper is part I of a revised version of astro-ph/0110344. The full version of
Tables 2 and 3, i.e. the tables listing the photometric and spectroscopic
parameters of ~ 9000 galaxies, are available at
http://astrophysics.phys.cmu.edu/~bernardi/SDSS/Etypes/TABLE
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