First assessment of Mercury (Hg) concentrations in skin and Carapace of Flatback Turtles (Natator depressus) (Garman) from Western Australia

Mercury pollution in the surface ocean has more than doubled over the past century. Within oceanic food webs, sea turtles have life history characteristics that make them especially vulnerable to mercury (Hg) accumulation. In this study we investigated Hg concentrations in the skin and carapace of nesting flatback turtles (Natator depressus) from two rookeries in Western Australia. A total of 50 skin samples and 52 carapace samples were collected from nesting turtles at Thevenard Island, and 23 skin and 28 carapace samples from nesting turtles at Eighty Mile Beach. We tested the influence of turtle size on Hg concentrations, hypothesising that larger and likely older adult turtles would exhibit higher concentrations due to more prolonged exposure to Hg. We compared the rookeries, hypothesising that the turtles from the southern rookery (Thevenard Island) were more likely to forage and reside in the Pilbara region closer to industrial mining activity and loading ports (potential exposure to higher environmental Hg concentrations) with turtles from the northern rookery (Eighty Mile Beach) more likely to reside and feed in the remote Kimberley. Turtles from the Eighty Mile Beach rookery had significantly higher skin Hg concentrations (x̄ = 19.4 ± 4.8 ng/g) than turtles from Thevenard Island (x̄ = 15.2 ± 5.8 ng/g). There was no significant difference in carapace Hg concentrations in turtles between Eighty Mile Beach (x̄ = 48.4 ± 21.8 ng/g) and Thevenard Island (x̄ = 41.3 ± 16.5 ng/g). Turtle size did not explain Hg concentrations in skin samples from Eighty Mile Beach and Thevenard Island, but turtle size explained 43.1% of Hg concentrations in the carapace of turtles from Eighty Mile Beach and 44.2% from Thevenard Island. Mercury concentrations in the flatback turtles sampled in this study are relatively low compared to other sea turtles worldwide, likely a result of the generally low concentrations of Hg in the Australian environment. Although we predicted that mining activities would influence flatback turtle Hg bioaccumulations, our data did not support this effect. This may be a result of foraging ground overlap between the two rookeries, or the predominant wind direction carrying atmospheric Hg inland rather than seaward. This is the first Hg study in skin and carapace of flatback turtles and represents a baseline to compare Hg contamination in Australia’s surrounding oceans

Tensor completion in hierarchical tensor representations

Compressed sensing extends from the recovery of sparse vectors from undersampled measurements via efficient algorithms to the recovery of matrices of low rank from incomplete information. Here we consider a further extension to the reconstruction of tensors of low multi-linear rank in recently introduced hierarchical tensor formats from a small number of measurements. Hierarchical tensors are a flexible generalization of the well-known Tucker representation, which have the advantage that the number of degrees of freedom of a low rank tensor does not scale exponentially with the order of the tensor. While corresponding tensor decompositions can be computed efficiently via successive applications of (matrix) singular value decompositions, some important properties of the singular value decomposition do not extend from the matrix to the tensor case. This results in major computational and theoretical difficulties in designing and analyzing algorithms for low rank tensor recovery. For instance, a canonical analogue of the tensor nuclear norm is NP-hard to compute in general, which is in stark contrast to the matrix case. In this book chapter we consider versions of iterative hard thresholding schemes adapted to hierarchical tensor formats. A variant builds on methods from Riemannian optimization and uses a retraction mapping from the tangent space of the manifold of low rank tensors back to this manifold. We provide first partial convergence results based on a tensor version of the restricted isometry property (TRIP) of the measurement map. Moreover, an estimate of the number of measurements is provided that ensures the TRIP of a given tensor rank with high probability for Gaussian measurement maps.Comment: revised version, to be published in Compressed Sensing and Its Applications (edited by H. Boche, R. Calderbank, G. Kutyniok, J. Vybiral

Inter-cultural differences in response to a computer-based anti-bullying intervention

Background and purpose: Many holistic anti-bullying interventions have been attempted, with mixed success, while little work has been done to promote a 'self-help' approach to victimisation. The rise of the ICT curriculum and computer support in schools now allows for approaches that benefit from technology to be implemented. This study evaluates the cross-cultural effects of a computer-based anti-bullying intervention on primary school-aged children's knowledge about bullying and relevant coping strategies. Programme description: FearNot! is an interactive computer-based virtual learning environment designed for use as an anti-bullying intervention. It includes interactive virtual agents who assume the most common participant roles found in episodes of bullying. FearNot! was used by children over three consecutive weeks to allow its effectiveness to be evaluated in a longitudinal in situ programme. Sample: Two comparable samples were drawn from the UK and Germany. In the UK, 651 participants (aged 8-11) were recruited from primary schools in Hertfordshire, Coventry and Warwickshire, whereas the 535 German participants (aged 7-10) were sourced from Grundschulen in the Bayern and Hessen regions. Because of lack of parental consent, late joiners and absences/missing responses, data from 908 participants (UK 493; Germany 415) were analysed. Design and methods: A quasi-experimental, pre/post-tests control group design employed pre-published and bespoke questionnaires to collect data. Descriptive and inferential analyses were conducted. Results: UK students possessed higher coping strategy knowledge scores than German participants, but German children's scores improved over time and as a result of the FearNot! intervention. Conclusions: Overall, while not effective at increasing children's coping strategy knowledge in this study, the FearNot! intervention could prove a useful classroom tool to approach the issue of bullying as part of a wider initiative. Cultural differences at baseline and reactions to the intervention are discussed

Last interglacial temperature evolution – a model inter-comparison

Abstract. There is a growing number of proxy-based reconstructions detailing the climatic changes during the Last Interglacial period. This period is of special interest because large parts of the globe were characterized by a warmer-than-present-day climate, making this period an interesting test bed for climate models in the light of projected global warming. However, mainly because synchronizing the different records is difficult, there is no consensus on a global picture of Last Interglacial temperature changes. Here we present the first model inter-comparison of transient simulations covering the Last Interglacial period. By comparing the different simulations we aim at investigating the robustness of the simulated surface air temperature evolution. The model inter-comparison shows a robust Northern Hemisphere July temperature evolution characterized by a maximum between 130–122 ka BP with temperatures 0.4 to 6.8 K above pre-industrial values. This temperature evolution is in line with the changes in June insolation and greenhouse-gas concentrations. For the evolution of July temperatures in the Southern Hemisphere, the picture emerging from the inter-comparison is less clear. However, it does show that including greenhouse-gas concentration changes is critical. The simulations that include this forcing show an early, 128 ka BP July temperature anomaly maximum of 0.5 to 2.6 K. The robustness of simulated January temperatures is large in the Southern Hemisphere and the mid-latitudes of the Northern Hemisphere. In these latitudes maximum January temperature anomalies of respectively −2.5 to 2 K and 0 to 2 K are simulated for the period after 118 ka BP. The inter-comparison is inconclusive on the evolution of January temperatures in the high-latitudes of the Northern Hemisphere. Further investigation of regional anomalous patterns and inter-model differences indicate that in specific regions, feedbacks within the climate system are important for the simulated temperature evolution. Firstly in the Arctic region, changes in the summer sea-ice cover control the evolution of Last Interglacial winter temperatures. Secondly, for the Atlantic region, the Southern Ocean and the North Pacific, possible changes in the characteristics of the Atlantic meridional overturning circulation are critical. The third important feedback, having an impact on the temperature evolution of the Northern Hemisphere, is shown to be the presence of remnant continental ice from the preceding glacial period. Another important feedback are changes in the monsoon regime which controls the evolution of temperatures over parts of Africa and India. Finally, the simulations reveal an important land-sea contrast, with temperature changes over the oceans lagging continental temperatures by up to several thousand years. The aforementioned feedback mechanisms tend to be highly model-dependent, indicating that specific proxy-data is needed to constrain future climate simulations and to further enhance our understanding of the evolution of the climate during the Last Interglacial period

Using the past to constrain the future: how the palaeorecord can improve estimates of global warming

Climate sensitivity is defined as the change in global mean equilibrium temperature after a doubling of atmospheric CO2 concentration and provides a simple measure of global warming. An early estimate of climate sensitivity, 1.5-4.5{\deg}C, has changed little subsequently, including the latest assessment by the Intergovernmental Panel on Climate Change. The persistence of such large uncertainties in this simple measure casts doubt on our understanding of the mechanisms of climate change and our ability to predict the response of the climate system to future perturbations. This has motivated continued attempts to constrain the range with climate data, alone or in conjunction with models. The majority of studies use data from the instrumental period (post-1850) but recent work has made use of information about the large climate changes experienced in the geological past. In this review, we first outline approaches that estimate climate sensitivity using instrumental climate observations and then summarise attempts to use the record of climate change on geological timescales. We examine the limitations of these studies and suggest ways in which the power of the palaeoclimate record could be better used to reduce uncertainties in our predictions of climate sensitivity.Comment: The final, definitive version of this paper has been published in Progress in Physical Geography, 31(5), 2007 by SAGE Publications Ltd, All rights reserved. \c{opyright} 2007 Edwards, Crucifix and Harriso

A Single Laser System for Ground-State Cooling of 25-Mg+

We present a single solid-state laser system to cool, coherently manipulate and detect $^{25}$Mg$^+$ ions. Coherent manipulation is accomplished by coupling two hyperfine ground state levels using a pair of far-detuned Raman laser beams. Resonant light for Doppler cooling and detection is derived from the same laser source by means of an electro-optic modulator, generating a sideband which is resonant with the atomic transition. We demonstrate ground-state cooling of one of the vibrational modes of the ion in the trap using resolved-sideband cooling. The cooling performance is studied and discussed by observing the temporal evolution of Raman-stimulated sideband transitions. The setup is a major simplification over existing state-of-the-art systems, typically involving up to three separate laser sources

Toward understanding covid-19 recovery: national institutes of health workshop on postacute covid-19

Over the past year, the SARS-CoV-2 pandemic has swept the globe, resulting in an enormous worldwide burden of infection and mortality. However, the additional toll resulting from long-term consequences of the pandemic has yet to be tallied. Heterogeneous disease manifestations and syndromes are now recognized among some persons after their initial recovery from SARS-CoV-2 infection, representing in the broadest sense a failure to return to a baseline state of health after acute SARS-CoV-2 infection. On 3 to 4 December 2020, the National Institute of Allergy and Infectious Diseases, in collaboration with other Institutes and Centers of the National Institutes of Health, convened a virtual workshop to summarize existing knowledge on postacute COVID-19 and to identify key knowledge gaps regarding this condition

Toward an internally consistent astronomical distance scale

Accurate astronomical distance determination is crucial for all fields in astrophysics, from Galactic to cosmological scales. Despite, or perhaps because of, significant efforts to determine accurate distances, using a wide range of methods, tracers, and techniques, an internally consistent astronomical distance framework has not yet been established. We review current efforts to homogenize the Local Group's distance framework, with particular emphasis on the potential of RR Lyrae stars as distance indicators, and attempt to extend this in an internally consistent manner to cosmological distances. Calibration based on Type Ia supernovae and distance determinations based on gravitational lensing represent particularly promising approaches. We provide a positive outlook to improvements to the status quo expected from future surveys, missions, and facilities. Astronomical distance determination has clearly reached maturity and near-consistency.Comment: Review article, 59 pages (4 figures); Space Science Reviews, in press (chapter 8 of a special collection resulting from the May 2016 ISSI-BJ workshop on Astronomical Distance Determination in the Space Age

POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumors

Human germ cell tumors (GCTs) may have variable histology and clinical behavior, depending on factors such as sex of the patient, age at clinical diagnosis, and anatomical site of the tumor. Some types of GCT, i.e., the seminomas/germinomas/dysgerminomas and embryonal carcinomas (the stem cell component of nonseminomas), have pluripotent potential, which is demonstrated by their capacity to differentiate into somatic and/or extraembryonic elements. Although embryonal carcinoma cells are intrinsically pluripotent, seminoma/germinoma/dysgerminoma cells, as well as their precursor carcinoma in situ/gonadoblastoma cells, have the phenotype of early germ cells that can be activated to pluripotency. The other types of GCT (teratomas and yolk sac tumors of infants and newborn, dermoid cyst of the ovary, and spermatocytic seminoma of elderly) are composed of (fully) differentiated tissues and lack the appearance of undifferentiated and pluripotent stem cells. OCT3/4, a transcription factor also known as OTF3 and POU5F1, is involved in regulation of pluripotency during normal development and is detectable in embryonic stem and germ cells. We analyzed the presence of POU5F1 in GCT and other tumor types using immunohistochemistry. The protein was consistently detected in carcinoma in situ/gonadoblasto