43 research outputs found
On the Lorentz structure of the symmetry energy
We investigate in detail the density dependence of the symmetry energy in a
relativistic description by decomposing the iso-vector mean field into
contributions with different Lorentz covariant properties. We find important
effects of the iso-vector, scalar channel (i.e. -meson like) on the
high density behavior of the symmetry energy. Applications to static properties
of finite nuclei and to dynamic situations of heavy ion collisions are explored
and related to each other. The nuclear structure studies show only moderate
effects originating from the virtual meson. At variance, in heavy ion
collisions one finds important contributions on the reaction dynamics arising
from the different Lorentz structure of the high density symmetry energy when a
scalar iso-vector field is introduced. Particularly interesting is the
related neutron/proton effective mass splitting for nucleon transport effects
and for resonance and particle production around the threshold. We show that
the -like channel turns out to be essential for the production of
pions, when comparing with experimental data, in particular for high momentum
selections.Comment: 30 pages, 12 figures (.eps
Ecological connectivity between the areas beyond national jurisdiction and coastal waters: Safeguarding interests of coastal communities in developing countries
The UN General Assembly has made a unanimous decision to start negotiations to establish an international, legally-binding instrument for the conservation and sustainable use of marine biological diversity within Areas Beyond National Jurisdiction (ABNJ). However, there has of yet been little discussion on the importance of this move to the ecosystem services provided by coastal zones in their downstream zone of influence. Here, we identify the ecological connectivity between ABNJ and coastal zones as critically important in the negotiation process and apply several approaches to identify some priority areas for protection from the perspective of coastal populations of Least Developed Countries (LDCs). Initially, we review the scientific evidence that demonstrates ecological connectivity between ABNJ and the coastal zones with a focus on the LDCs. We then use ocean modelling to develop a number of metrics and spatial maps that serve to quantify the connectivity of the ABNJ to the coastal zone. We find that the level of exposure to the ABNJ influences varies strongly between countries. Similarly, not all areas of the ABNJ are equal in their impacts on the coastline. Using this method, we identify the areas of the ABNJ that are in the most urgent need of protection on the grounds of the strength of their potential downstream impacts on the coastal populations of LDCs. We argue that indirect negative impacts of the ABNJ fishing, industrialisation and pollution, communicated via oceanographic, cultural and ecological connectivity to the coastal waters of the developing countries should be of concern
Long-term course of L-dopa-responsive dystonia caused by tyrosine hydroxylase deficiency.
Contains fulltext :
57504.pdf (publisher's version ) (Closed access)The authors report the long-term course of two siblings with L-dopa responsive dystonia (DRD) associated with a compound heterozygous mutation in the tyrosine hydroxylase (TH) gene. Both siblings manifested with lower-limb onset generalized DRD and had a sustained response to low-dose L-dopa therapy for over 35 years. Although the l-dopa therapy was delayed up to 20 years after disease onset, there were no cognitive or neurologic sequelae of the long-term catecholamine deficit