6,648 research outputs found
Roofing Nail Performance In Structural Flakeboards
Phenolic structural flakeboard might be commonly used as roof and wall sheathing and as subfloor panels in housing. Important in the acceptability of such flakeboard as roof sheathing is the ability to hold the shingles in place. Failure of the roofing nails to perform this function is exhibited by nail "pop"—the slow natural withdrawal of a nail due to shrinkage and swelling of the panel and shingles. Such tendency of 1-inch roofing nails that had been driven into and through commercial and experimental flakeboards was compared with that in 5-ply exterior grade Douglas-fir plywood. Cyclic moisture conditions (including freeze-thaw) were generated employing an ASTM accelerated aging procedure. Nail pop was not evidenced in any of the panels. Rather, the nailheads were observed to subside further into shingle and panel surfaces with increasing exposure. This subsidence was highly correlated to the thickness swell of the panels. It can be concluded that nail pop will not be a problem with nails driven through the flakeboard
ddml: Double/debiased machine learning in Stata
We introduce the package ddml for Double/Debiased Machine Learning (DDML) in
Stata. Estimators of causal parameters for five different econometric models
are supported, allowing for flexible estimation of causal effects of endogenous
variables in settings with unknown functional forms and/or many exogenous
variables. ddml is compatible with many existing supervised machine learning
programs in Stata. We recommend using DDML in combination with stacking
estimation which combines multiple machine learners into a final predictor. We
provide Monte Carlo evidence to support our recommendation.Comment: The package can be installed from https://github.com/aahrens1/ddml
Native architecture of the Chlamydomonas chloroplast revealed by in situ cryo-electron tomography
Chloroplast function is orchestrated by the organelle's intricate architecture. By combining cryo-focused ion beam milling of vitreous Chlamydomonas cells with cryo-electron tomography, we acquired three-dimensional structures of the chloroplast in its native state within the cell. Chloroplast envelope inner membrane invaginations were frequently found in close association with thylakoid tips, and the tips of multiple thylakoid stacks converged at dynamic sites on the chloroplast envelope, implicating lipid transport in thylakoid biogenesis. Subtomogram averaging and nearest neighbor analysis revealed that RuBisCO complexes were hexagonally packed within the pyrenoid, with similar to 15 nm between their centers. Thylakoid stacks and the pyrenoid were connected by cylindrical pyrenoid tubules, physically bridging the sites of light-dependent photosynthesis and light-independent carbon fixation. Multiple parallel minitubules were bundled within each pyrenoid tubule, possibly serving as conduits for the targeted one-dimensional diffusion of small molecules such as ATP and sugars between the chloroplast stroma and the pyrenoid matrix
Why Compact Tori For Fusion?
A compact torus (CT) has a toroidal magnetic and plasma geometry, but is contained within a simply-connected vacuum vessel such as a cylinder. Spheromaks and field-reversed configurations fall into this category. Compact tori are translatable and have a high engineering beta. The primary benefit of CTs for fusion is the absence of toroidal field and Ohmic Heating coils and the many problems brought on by them. Studying fusion-relevant plasma in simply-connected geometries affords the world fusion program both physics and technology opportunities not found in other configurations. This paper outlines the technology and physics opportunities of compact tori, and presents a cost model based on geometry for comparison with less compact configurations
Genome-wide changes in protein translation efficiency are associated with autism
We previously proposed that changes in the efficiency of protein translation are associated with autism spectrum disorders (ASDs). This hypothesis connects environmental factors and genetic factors because each can alter translation efficiency. For genetic factors, we previously tested our hypothesis using a small set of ASD-associated genes, a small set of ASD-associated variants, and a statistic to quantify by how much a single nucleotide variant (SNV) in a protein coding region changes translation speed. In this study, we confirm and extend our hypothesis using a published set of 1,800 autism quartets (parents, one affected child and one unaffected child) and genome-wide variants. Then, we extend the test statistic to combine translation efficiency with other possibly relevant variables: ribosome profiling data, presence/absence of CpG dinucleotides, and phylogenetic conservation. The inclusion of ribosome profiling abundances strengthens our results for male–male sibling pairs. The inclusion of CpG information strengthens our results for female–female pairs, giving an insight into the significant gender differences in autism incidence. By combining the single-variant test statistic for all variants in a gene, we obtain a single gene score to evaluate how well a gene distinguishes between affected and unaffected siblings. Using statistical methods, we compute gene sets that have some power to distinguish between affected and unaffected siblings by translation efficiency of gene variants. Pathway and enrichment analysis of those gene sets suggest the importance of Wnt signaling pathways, some other pathways related to cancer, ATP binding, and ATP-ase pathways in the etiology of ASDs
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Fish Bulletin 180. California Coastal Salmonid Population Monitoring: Strategy, Design, and Methods
California’s salmon and steelhead populations have experienced marked declines leading to listing of almost all of California’s anadromous salmonids under the California Endangered Species Act (CESA) and Federal Endan-gered Species Act (ESA). Both CESA and ESA listings require recovery plans that call for monitoring to provide some measure of progress toward recovery. In addition, there are related monitoring needs for other management activi-ties such as hatchery operations and fisheries management
Typical-Medium Theory of Mott-Anderson Localization
The Mott and the Anderson routes to localization have long been recognized as
the two basic processes that can drive the metal-insulator transition (MIT).
Theories separately describing each of these mechanisms were discussed long
ago, but an accepted approach that can include both has remained elusive. The
lack of any obvious static symmetry distinguishing the metal from the insulator
poses another fundamental problem, since an appropriate static order parameter
cannot be easily found. More recent work, however, has revisited the original
arguments of Anderson and Mott, which stressed that the key diference between
the metal end the insulator lies in the dynamics of the electron. This physical
picture has suggested that the "typical" (geometrically averaged) escape rate
from a given lattice site should be regarded as the proper dynamical order
parameter for the MIT, one that can naturally describe both the Anderson and
the Mott mechanism for localization. This article provides an overview of the
recent results obtained from the corresponding Typical-Medium Theory, which
provided new insight into the the two-fluid character of the Mott-Anderson
transition.Comment: to be published in "Fifty Years of Anderson localization", edited by
E. Abrahams (World Scientific, Singapore, 2010); 29 pages, 22 figures
Mass modification of D-meson in hot hadronic matter
We evaluate the in-medium and -meson masses in hot hadronic
matter induced by interactions with the light hadron sector described in a
chiral SU(3) model. The effective Lagrangian approach is generalized to SU(4)
to include charmed mesons. We find that the D-mass drops substantially at
finite temperatures and densities, which open the channels of the decay of the
charmonium states (, , ) to pairs in
the thermal medium. The effects of vacuum polarisations from the baryon sector
on the medium modification of the -meson mass relative to those obtained in
the mean field approximation are investigated. The results of the present work
are compared to calculations based on the QCD sum-rule approach, the
quark-meson coupling model, chiral perturbation theory, as well as to studies
of quarkonium dissociation using heavy quark potential from lattice QCD.Comment: 18 pages including 7 figures, minor revision of the text, figure
styles modified, to appear in Phys. Rev.
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