23 research outputs found
Emergent Semantics and Cooperation in Multi-knowledge Communities: the ESTEEM Approach
15In the present global society, information has to be exchangeable in open and dynamic environments, where interacting users do not necessarily share a common understanding of the world at hand. This is particularly true in P2P scenarios, where millions of autonomous users (peers) need to cooperate by sharing their resources (such as data and services). We propose the Esteem approach (Emergent Semantics and cooperaTion in multi-knowledgE EnvironMents), where a comprehensive framework and a platform for data and service discovery in P2P systems are proposed, with advanced solutions for trust and quality-based data management, P2P infrastructure definition, query processing and dynamic service discovery in a context-aware scenario. In Esteem, semantic communities are built around declared interests in the form of manifesto ontologies and their autonomous nature is preserved by allowing a shared semantics to naturally emerge from the peer interactions. Inside the borders of semantic communities data and services are discovered, queried and invoked in a resource sharing scenario, where the context in which users interoperate and the trust of exchanged information are also relevant aspects to take into account.reservedmixedBianchini D.; Montanelli S.; Aiello C.; Baldoni R.; Bolchini C.; Bonomi S.; Castano S.; Catarci T.; De Antonellis V.; Ferrara A.; Melchiori M.; Quintarelli E.; Scannapieco M.; Schreiber F.A.; Tanca L.Bianchini, Devis; Montanelli, S.; Aiello, C.; Baldoni, R.; Bolchini, C.; Bonomi, S.; Castano, S.; Catarci, T.; DE ANTONELLIS, Valeria; Ferrara, A.; Melchiori, Michele; Quintarelli, E.; Scannapieco, M.; Schreiber, F. A.; Tanca, L
The ESTEEM platform: enabling P2P semantic collaboration through emerging collective knowledge
In this paper, we present Esteem (Emergent Semantics and cooperaTion in multi-knowledgE EnvironMents), a community-based P2P platform for supporting semantic collaboration among a set of independent peers, without prior reciprocal knowledge and no predefined relationships. Goal of Esteem is to go beyond the existing state-of-the-art solutions for P2P knowledge sharing and to provide an integrated platform for both data and service discovery. A distinguishing feature of Esteem is the use of semantic communities to explicitly give shape to the collective knowledge and expertise of peer groups with similar interests. Key techniques of Esteem will be presented in the paper and concern: shuffling-based communication, ontology and service matchmaking, context management, and quality-aware data integration. An application example of data and service discovery in the health-care domain will be presented, by also discussing results of system and user evaluation
Emergent Semantics and Cooperation in Multi-knowledge Communities: the ESTEEM Approach
In the present global society, information has to be exchangeable in open and dynamic environments, where interacting users do not necessarily share a common understanding of the world at hand. This is particularly true in P2P scenarios, where millions of autonomous users (peers) need to cooperate by sharing their resources (such as data and services). We propose the Esteem approach (Emergent Semantics and cooperaTion in multi-knowledgE EnvironMents), where a comprehensive framework and a platform for data and service discovery in P2P systems are proposed, with advanced solutions for trust and quality-based data management, P2P infrastructure definition, query processing and dynamic service discovery in a context-aware scenario. In Esteem, semantic communities are built around declared interests in the form of manifesto ontologies and their autonomous nature is preserved by allowing a shared semantics to naturally emerge from the peer interactions. Inside the borders of semantic communities data and services are discovered, queried and invoked in a resource sharing scenario, where the context in which users interoperate and the trust of exchanged information are also relevant aspects to take into account
Streptococcus gordonii's sequenced strain CH1 glucosyltransferase determines persistent but not initial colonization of teeth of rats
Emergent semantics and cooperation in multi−knowledge environments: The ESTEEM architecture
In the present global society, information has to be exchangeable in open and dynamic environments, where interacting peers do not necessarily share a common understanding of the world at hand, and do not have a complete picture of the context where the interaction occurs. In this paper, we present the Esteem approach and the related peer architecture for emergent semantics in dynamic and multi-knowledge environments. In Esteem, semantic communities are built around declared interests in the form of manifesto ontologies, and their autonomous nature is preserved by allowing a shared semantics to naturally emerge from peer interactions
Emergent Semantics and Cooperation in Multi-Knowledge Environments: the ESTEEM Architecture
In the present global society, information has to be exchangeable in open and dynamic environments, where interacting peers do not necessarily share a common,understanding of the world at hand, and do not have a complete picture of the context where the interaction occurs. In this paper, we present the Esteem approach and the related peer architecture for emergent semantics in dynamic and multi-knowledge environments. In Esteem, semantic communities are built around declared interests in the form of manifesto ontologies, and their autonomous nature is preserved by allowing a shared semantics to naturally emerge, from peer interactions
Attributable mortality of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised prevention studies
Item does not contain fulltextBACKGROUND: Estimating attributable mortality of ventilator-associated pneumonia has been hampered by confounding factors, small sample sizes, and the difficulty of doing relevant subgroup analyses. We estimated the attributable mortality using the individual original patient data of published randomised trials of ventilator-associated pneumonia prevention. METHODS: We identified relevant studies through systematic review. We analysed individual patient data in a one-stage meta-analytical approach (in which we defined attributable mortality as the ratio between the relative risk reductions [RRR] of mortality and ventilator-associated pneumonia) and in competing risk analyses. Predefined subgroups included surgical, trauma, and medical patients, and patients with different categories of severity of illness scores. FINDINGS: Individual patient data were available for 6284 patients from 24 trials. The overall attributable mortality was 13%, with higher mortality rates in surgical patients and patients with mid-range severity scores at admission (ie, acute physiology and chronic health evaluation score [APACHE] 20-29 and simplified acute physiology score [SAPS 2] 35-58). Attributable mortality was close to zero in trauma, medical patients, and patients with low or high severity of illness scores. Competing risk analyses could be done for 5162 patients from 19 studies, and the overall daily hazard for intensive care unit (ICU) mortality after ventilator-associated pneumonia was 1.13 (95% CI 0.98-1.31). The overall daily risk of discharge after ventilator-associated pneumonia was 0.74 (0.68-0.80), leading to an overall cumulative risk for dying in the ICU of 2.20 (1.91-2.54). Highest cumulative risks for dying from ventilator-associated pneumonia were noted for surgical patients (2.97, 95% CI 2.24-3.94) and patients with mid-range severity scores at admission (ie, cumulative risks of 2.49 [1.81-3.44] for patients with APACHE scores of 20-29 and 2.72 [1.95-3.78] for those with SAPS 2 scores of 35-58). INTERPRETATION: The overall attributable mortality of ventilator-associated pneumonia is 13%, with higher rates for surgical patients and patients with a mid-range severity score at admission. Attributable mortality is mainly caused by prolonged exposure to the risk of dying due to increased length of ICU stay. FUNDING: None