Dilemmas of Rawlsian Opportunity

John Rawls's repeated assertions that the basic structure of society creates profound and inevitable differences in life prospects for people born in different starting places seems to contradict his assertions that, under fair equality of opportunity, a person's life prospects would not be affected by class of origin for those similarly endowed and motivated. This seeming contradiction seems to be resolved by Rawls's apparent belief that class of origin inevitably affects motivation. This reconciliation leaves us with a very weak conception of "fair equality of opportunity." Should Rawls have advocated something stronger? Within the constraints of his theory of justice nothing stronger seems possible. Still, his theory harbors highly implausible sociological assumptions. A more plausible sociology requires us to reject distributive justice in favor of contributive justice

Resampling Strategies to Estimate Mean Concentrations from Low SNR In Vivo MR Spectra

A resampling method for quantitative MRS is presented that retains absolute concentrations. Averaging the spectra from a subset improved the concentrationestimates via increased SNR. Using short-TE STEAM spectra from human thalamus, the influence of subset size was systematically studied and verifiedagainst conventional bootstrap re-sampling. Even small subsets provided considerably better signal-to-noise ratio and reliability. The standard deviation orconfidence intervals can be derived by correcting the variance over all subset estimates for the inherent redundancy. Subsets of about half the group size arerecommended, because of their large number and the almost normal distribution of mean concentration estimates

Reprint of “Structural and functional correlates of epileptogenesis — Does gender matter?"

In the majority of neuropsychiatric conditions, marked gender-based differences have been found in the epidemiology,clinical manifestations, and therapy of disease. One possible reason is that sex differences in cerebral morphology, structural and functional connections, render men and women differentially vulnerable to various disease processes. The present review addresses this issue with respect to the functional and structural correlates to some forms of epilepsy

Reprint of "Structural and functional correlates of epileptogenesis--does gender matter?".

In the majority of neuropsychiatric conditions, marked gender-based differences have been found in the epidemiology,clinical manifestations, and therapy of disease. One possible reason is that sex differences in cerebral morphology, structural and functional connections, render men and women differentially vulnerable to various disease processes. The present review addresses this issue with respect to the functional and structural correlates to some forms of epilepsy

Androstenol – a Steroid Derived Odor Activates the Hypothalamus in Women

Background: Whether pheromone signaling exists in humans is still a matter of intense discussion. In the present study we tested if smelling of Androstenol, a steroid produced by the human body and reported to affect human behavior, may elicit cerebral activation. A further issue was to evaluate whether the pattern of activation resembles the pattern of common odors. Methodology: PET measurements of regional cerebral blood flow (rCBF) were conducted in 16 healthy heterosexual women during passive smelling of Androstenol, four ordinary odors (OO), and odorless air (the base line condition). Principal findings: Smelling Androstenol caused activation of a portion of the hypothalamus, which according to animal data mediates the pheromone triggered mating behavior. Smelling of OO, on the other hand, engaged only the classical olfactory regions (the piriform cortex, lateral amygdala, anterior insular and anterior cingulate cortex). Conclusions: The observed pattern of activation is very similar to the pattern previously detected with 4,16-androstadien-3one in heterosexual females. It suggests that several compounds released by human body may activate cerebral networks involved in human reproduction

Reprint of "Structural and functional correlates of epileptogenesis--does gender matter?".

In the majority of neuropsychiatric conditions, marked gender-based differences have been found in the epidemiology,clinical manifestations, and therapy of disease. One possible reason is that sex differences in cerebral morphology, structural and functional connections, render men and women differentially vulnerable to various disease processes. The present review addresses this issue with respect to the functional and structural correlates to some forms of epilepsy

Structural and functional correlates of epileptogenesis - does gender matter?

In the majority of neuropsychiatric conditions, marked gender-based differences have been found in the epidemiology, clinical manifestations, and therapy of disease. One possible reason is that sex differences in cerebral morphology, structural and functional connections, render men and women differentially vulnerable to various disease processes. The present review addresses this issue with respect to the functional and structural correlates to some forms of epilepsy