‘Educative leisure’ and the art museum

This paper argues that although museums have increasingly changed their mission to embrace ‘spectacular’ and ‘commercial’ goals in recent decades, their audiences resist this redefinition of the museum’s role. Based on a structural equation model derived from a survey of 1,900 visitors of the six main galleries of modern and contemporary art in Belgium, it shows that different kinds of visitors tend to share the same conceptualization of what museums signify, as a kind of ‘educative leisure’. They continue to differentiate museums from more commercial forms of leisure, and associate them with schooling and educational processes. We demonstrate that this appreciation of ‘educative leisure’ is shared by visitors from different socio-demographic backgrounds and is affected by other dimensions of the visitors’ profiles, such as the practice of creative activities or recent experiences of other art places (commercial galleries, fairs, contemporary art centers)

Operationalisation of European Identity, Cosmopolitanism and Cross-Border Practices

In this document we explore how the three key concepts of the EUCROSS project can effectively be operationalised in survey research. We see this step as an essential precondition to the development of the survey instrument itself, and as a contribution to the operationalisation of these concerns by other researchers, including outside the EUCROSS project. On the former point, our survey is only a 20 minute phone interview, and this format will necessarily constrain our question range and depth. However, our pragmatic choices should still be guided by a wider recognition of what questions might ideally be asked in view of experiences and findings from other projects. On the latter point, all three concepts are ones that interest a great many social scientists, yet there remains a stand-off between theorists of these concepts and qualitative researchers on the one hand, and those who use such concepts in survey research. We hope our operationalisation document may usefully bridge this divide, to some extent at least

Europeanisation and globalisation

Our paper will show preliminary results of the FP7 EUCROSS project to examine the scope and nature of cross-border practices within six European nations (Germany, Italy, Spain, UK, Denmark and Romania), based on a quantitative survey undertaken on a random telephone sample of more than 6,000 EU residents. The paper presents the results of two hierarchical logistic regressions assessing the extent to which cross-border practices (mobility and consumption practices) can be associated with both European and global identities (feeling European - feeling citizen of the world). We show that transnational consumption practices are crucially associated with both European and global identities, and indeed are more important than socio-demographic variables and personal experiences of mobility. The systematic comparison of the results of both regressions helps us disentangle processes of cosmopolitisation and europeanisation of daily lives in the context of globalisation. Are the most mobile the most European? Or is it only some specific practices that trigger a higher affinity with the idea of Europe? Can cross-border practices be related to a greater cosmopolitan attitude defined as openness to diversity? We show that specific cross-border practices related to Europe (e.g. purchase in the EU – and not outside the EU, preferences for European cuisines, familiarity with specifically European countries) are associated with a stronger European identity. Other practices are associated with a global identity, such as listening to global music, indicating a certain degree of differentiation between the two processes

Cultural sociology and new forms of distinction

In recent years growing sociological interest in new forms of cultural distinction has led some to argue that the advantages previously conveyed by the consumption of ‘high’ culture ‘or ‘omnivorousness’ are being overwritten by the possession of what has been termed ‘emerging cultural capital’. So far, though, this term has only been discussed in passing within empirical work and remains in need of further analytical specification. This special issue seeks to both critically interrogate and develop this concept by bringing together the work of leading cultural sociologists around four key themes: the role of age and generation in the formation of cultural capital; the power of visual display for distinction; the significance of new elite cultures; and the need for methodological pluralism to apprehend the expressions and mechanisms of distinction. This editorial introduction outlines the descriptive terrain on which the concept of emerging cultural capital has rested until now before exploring the common themes that sit across all five papers in the special issue

Creating a Professional Development Plan for a Simulation Consortium

As the United States struggles with health care reform and a nursing education system that inadequately prepares students for practice, dramatic advances in educational technology signal opportunities for both academic and practicing nurses to affect our profession as never before. Simulation technologies provide large and small institutions with the means to educate health care students and novice professionals effectively and efficiently through hands-on experience, but the costs of such a venture can be prohibitive. A simulation consortium offers a venue for different health care and educational institutions with shared goals to pool knowledge, monies, and labor toward health care education throughout a geographic area. This article details one Midwestern U.S. region's work in creating a professional development plan for a new simulation consortium

Semi-supervised learning towards automated segmentation of PET images with limited annotations: Application to lymphoma patients

The time-consuming task of manual segmentation challenges routine systematic quantification of disease burden. Convolutional neural networks (CNNs) hold significant promise to reliably identify locations and boundaries of tumors from PET scans. We aimed to leverage the need for annotated data via semi-supervised approaches, with application to PET images of diffuse large B-cell lymphoma (DLBCL) and primary mediastinal large B-cell lymphoma (PMBCL). We analyzed 18F-FDG PET images of 292 patients with PMBCL (n=104) and DLBCL (n=188) (n=232 for training and validation, and n=60 for external testing). We employed FCM and MS losses for training a 3D U-Net with different levels of supervision: i) fully supervised methods with labeled FCM (LFCM) as well as Unified focal and Dice loss functions, ii) unsupervised methods with Robust FCM (RFCM) and Mumford-Shah (MS) loss functions, and iii) Semi-supervised methods based on FCM (RFCM+LFCM), as well as MS loss in combination with supervised Dice loss (MS+Dice). Unified loss function yielded higher Dice score (mean +/- standard deviation (SD)) (0.73 +/- 0.03; 95% CI, 0.67-0.8) compared to Dice loss (p-value<0.01). Semi-supervised (RFCM+alpha*LFCM) with alpha=0.3 showed the best performance, with a Dice score of 0.69 +/- 0.03 (95% CI, 0.45-0.77) outperforming (MS+alpha*Dice) for any supervision level (any alpha) (p<0.01). The best performer among (MS+alpha*Dice) semi-supervised approaches with alpha=0.2 showed a Dice score of 0.60 +/- 0.08 (95% CI, 0.44-0.76) compared to another supervision level in this semi-supervised approach (p<0.01). Semi-supervised learning via FCM loss (RFCM+alpha*LFCM) showed improved performance compared to supervised approaches. Considering the time-consuming nature of expert manual delineations and intra-observer variabilities, semi-supervised approaches have significant potential for automated segmentation workflows

Telomere Length and the Risk of Cutaneous Malignant Melanoma in Melanoma-Prone Families with and without CDKN2A Mutations

Introduction: Recent evidence suggests a link between constitutional telomere length (TL) and cancer risk. Previous studies have suggested that longer telomeres were associated with an increased risk of melanoma and larger size and number of nevi. The goal of this study was to examine whether TL modified the risk of melanoma in melanoma-prone families with and without CDKN2A germline mutations. Materials and Methods We measured TL in blood DNA in 119 cutaneous malignant melanoma (CMM) cases and 208 unaffected individuals. We also genotyped 13 tagging SNPs in TERT. Results: We found that longer telomeres were associated with an increased risk of CMM (adjusted OR = 2.81, 95% CI = 1.02–7.72, P = 0.04). The association of longer TL with CMM risk was seen in CDKN2A- cases but not in CDKN2A+ cases. Among CMM cases, the presence of solar injury was associated with shorter telomeres (P = 0.002). One SNP in TERT, rs2735940, was significantly associated with TL (P = 0.002) after Bonferroni correction. Discussion Our findings suggest that TL regulation could be variable by CDKN2A mutation status, sun exposure, and pigmentation phenotype. Therefore, TL measurement alone may not be a good marker for predicting CMM risk

Effect of a reduction in glomerular filtration rate after nephrectomy on arterial stiffness and central hemodynamics: rationale and design of the EARNEST study

Background: There is strong evidence of an association between chronic kidney disease (CKD) and cardiovascular disease. To date, however, proof that a reduction in glomerular filtration rate (GFR) is a causative factor in cardiovascular disease is lacking. Kidney donors comprise a highly screened population without risk factors such as diabetes and inflammation, which invariably confound the association between CKD and cardiovascular disease. There is strong evidence that increased arterial stiffness and left ventricular hypertrophy and fibrosis, rather than atherosclerotic disease, mediate the adverse cardiovascular effects of CKD. The expanding practice of live kidney donation provides a unique opportunity to study the cardiovascular effects of an isolated reduction in GFR in a prospective fashion. At the same time, the proposed study will address ongoing safety concerns that persist because most longitudinal outcome studies have been undertaken at single centers and compared donor cohorts with an inappropriately selected control group.&lt;p&gt;&lt;/p&gt; Hypotheses: The reduction in GFR accompanying uninephrectomy causes (1) a pressure-independent increase in aortic stiffness (aortic pulse wave velocity) and (2) an increase in peripheral and central blood pressure.&lt;p&gt;&lt;/p&gt; Methods: This is a prospective, multicenter, longitudinal, parallel group study of 440 living kidney donors and 440 healthy controls. All controls will be eligible for living kidney donation using current UK transplant criteria. Investigations will be performed at baseline and repeated at 12 months in the first instance. These include measurement of arterial stiffness using applanation tonometry to determine pulse wave velocity and pulse wave analysis, office blood pressure, 24-hour ambulatory blood pressure monitoring, and a series of biomarkers for cardiovascular and bone mineral disease.&lt;p&gt;&lt;/p&gt; Conclusions: These data will prove valuable by characterizing the direction of causality between cardiovascular and renal disease. This should help inform whether targeting reduced GFR alongside more traditional cardiovascular risk factors is warranted. In addition, this study will contribute important safety data on living kidney donors by providing a longitudinal assessment of well-validated surrogate markers of cardiovascular disease, namely, blood pressure and arterial stiffness. If any adverse effects are detected, these may be potentially reversed with the early introduction of targeted therapy. This should ensure that kidney donors do not come to long-term harm and thereby preserve the ongoing expansion of the living donor transplant program.&lt;p&gt;&lt;/p&gt

Preference Transitivity and Symbolic Representation in Capuchin Monkeys (Cebus apella)

BACKGROUND: Can non-human animals comprehend and employ symbols? The most convincing empirical evidence comes from language-trained apes, but little is known about this ability in monkeys. Tokens can be regarded as symbols since they are inherently non-valuable objects that acquire an arbitrarily assigned value upon exchange with an experimenter. Recent evidence suggested that capuchin monkeys, which diverged from the human lineage 35 million years ago, can estimate, represent and combine token quantities. A fundamental and open question is whether monkeys can reason about symbols in ways similar to how they reason about real objects. METHODOLOGY/PRINCIPAL FINDINGS: Here we examined this broad question in the context of economic choice behavior. Specifically, we assessed whether, in a symbolic context, capuchins' preferences satisfy transitivity--a fundamental trait of rational decision-making. Given three options A, B and C, transitivity holds true if A > or = B, B > or = C and A > or = C (where > or = indicates preference). In this study, we trained monkeys to exchange three types of tokens for three different foods. We then compared choices monkeys made between different types of tokens with choices monkeys made between the foods. Qualitatively, capuchins' preferences revealed by the way of tokens were similar to those measured with the actual foods. In particular, when choosing between tokens, monkeys displayed strict economic preferences and their choices satisfied transitivity. Quantitatively, however, values measured by the way of tokens differed systematically from those measured with the actual foods. In particular, for any pair of foods, the relative value of the preferred food increased when monkeys chose between the corresponding tokens. CONCLUSIONS/SIGNIFICANCE: These results indicate that indeed capuchins are capable of treating tokens as symbols. However, as they do so, capuchins experience the cognitive burdens imposed by symbolic representation