Foot pedal operated fluid type exercising device

A foot pedal operated exercising device is reported that contains a dynamometer formed of a pair of cylinders each containing a piston. The pistons are linked to each other. The upper portions of the two cylinders are joined together by a common opening to provide a common fluid reservoir and each piston is provided with a one way check valve to maintain an adequate supply of working fluid. Fluid from the driven cylinder is transmitted to the other cylinder through separate constant force spring biased valves each valve takes the predominant portion of the pressure drop thereby providing a constant force hydraulic dynamometer. A device is provided to determine the amount of movement of piston travel

"It's the real thing": performance and murder in Sweden.

The article investigates contemporary experimental theatre in Sweden. It sums up and probes the implications of Sju tre (1999), the most controversial theatre production in Sweden in modern times. Lars Nor'n, the playwright and director, staged a dialogue involving three real convicts, of whom two were outspoken Nazis. The article explores the uncertain boundaries between aesthetic, ethical, and political issues with ramifications regarding the wider public opinion in Sweden, on racism and crime. It is methodologically motivated by reception research, performativity and idealogical discourse. By virtue of its performative impact, the theatrical event proved to be directly linked with critical questions of democracy, although conceivably at the expense of the artistic integrity of the director and the theatre as creator of public opinion. The article points to a paradox of democracy whereby hate speech is at once allowed and unjustified in the theatre as national arena. The actors are described and analysed as parasites in a societal body, that in Sju tre, becomes politically epitomised

Composite Finite Elements for Elliptic Boundary Value Problems with Discontinuous Coefficients

In this paper, we will introduce composite finite elements for solving elliptic boundary value problems with discontinuous coefficients. The focus is on problems where the geometry of the interfaces between the smooth regions of the coefficients is very complicated. On the other hand, efficient numerical methods such as, e.g., multigrid methods, wavelets, extrapolation, are based on a multi-scale discretization of the problem. In standard finite element methods, the grids have to resolve the structure of the discontinuous coefficients. Thus, straightforward coarse scale discretizations of problems with complicated coefficient jumps are not obvious. In this paper, we define composite finite elements for problems with discontinuous coefficients. These finite elements allow the coarsening of finite element spaces independently of the structure of the discontinuous coefficients. Thus, the multigrid method can be applied to solve the linear system on the fine scale. We focus on the construction of the composite finite elements and the efficient, hierarchical realization of the intergrid transfer operators. Finally, we present some numerical results for the multigrid method based on the composite finite elements (CFE-MG

Celecoxib decreases prostaglandin E\u3csub\u3e2\u3c/sub\u3e concentrations in nipple aspirate fluid from high risk postmenopausal women and women with breast cancer

Background Celecoxib inhibits PGE2 production in cancerous tissue. We previously reported that PGE2 levels in nipple aspirate fluid (NAF) and plasma were not decreased in women at increased breast cancer risk who received celecoxib 200 mg twice daily (bid). The endpoints of the current study were to determine if a short course of celecoxib 400 mg bid would decrease PGE2 levels in women 1) at increased breast cancer risk, and 2) with established breast cancer. Methods NAF and plasma samples were collected before, 2 weeks after taking celecoxib 400 mg bid, and two weeks after washout from 26 women who were at increased breast cancer risk. From 13 women with newly diagnosed breast cancer, NAF from the incident breast and plasma were collected before and on average 2 weeks after taking celecoxib. Additionally, in nine of the 13 women with breast cancer, NAF was collected from the contralateral breast. Results No consistent change in NAF or plasma PGE2 levels was noted in high risk premenopausal women. NAF PGE2 levels decreased after celecoxib administration in postmenopausal high risk women (p = 0.02), and in both the NAF (p = 0.02) and plasma (p = 0.03) of women with breast cancer. Conclusion Celecoxib 400 mg bid taken on average for 2 weeks significantly decreased NAF, but not plasma, PGE2 levels in postmenopausal high risk women, and decreased both NAF and plasma PGE2 levels in women with newly diagnosed breast cancer. PGE2 levels may predict celecoxib breast cancer prevention and treatment efficacy. Our observations are preliminary, and larger studies to confirm and extend these findings are warranted

Editorial: Safety monitoring for peripheral nerve blocks - Is there a state-of-the-art standard to avoid nerve injuries?

Highlights • Since there is only a low level of evidence, it is difficult to agree on state-of-the-art standards or to provide recommendations and guidelines. • The value of combining several monitoring devices for dual or triple guidance must be challenged. • The principle of fascial plane blocks is suitable to avoid traumatic needle-to-nerve contact. However, local toxicity must be regarded as a possible mechanism for nerve injuries. • Block procedures might be conducted during sedation or general anesthesia when considering the individual patients' clinical situations and the expertise of the anesthesiologist. • The quality of ultrasound equipment and education provided by the corresponding anesthesia department is highly relevan