2,498 research outputs found

    Struggling with the Freshman Fifteen: College Students’ Recollections of Parents’ Memorable Messages about Weight

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    Considering the college years are considered a critical time in one’s life for changes in diet and exercise behavior and an increase in weight gain, this study explored the significant and impactful communication between college students and their parents during this transitional period. Using open-ended responses to an online questionnaire (N = 222), we explored the Memorable Messages (Knapp, Stohl, & Reardon, 1981) college students recall receiving from their parents about overweight and obesity. Students’ responses demonstrate that not only is weight a difficult topic to talk about, but it is also a difficult issue for people to manage on an individual basis. Students gave examples of messages and conversations referencing their own and their parents’ struggles with weight, and their responses illustrate the complex nature (i.e., emotions, interpretations of compliments versus criticism) of these important communication episodes

    Ultracold Molecule Production Via a Resonant Oscillating Magnetic Field

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    A novel atom-molecule conversion technique has been investigated. Ultracold 85Rb atoms sitting in a dc magnetic field near the 155 G Feshbach resonance are associated by applying a small sinusoidal oscillation to the magnetic field. There is resonant atom to molecule conversion when the modulation frequency closely matches the molecular binding energy. We observe that the atom to molecule conversion efficiency depends strongly on the frequency, amplitude, and duration of the applied modulation and on the phase space density of the sample. This technique offers high conversion efficiencies without the necessity of crossing or closely approaching the Feshbach resonance and allows precise spectroscopic measurements. Efficiencies of 55% have been observed for pure Bose-Einstein condensates

    Language-Naive Chimpanzees (Pan troglodytes) Judge Relations Between Relations in a Conceptual Matching-to-Sample Task

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    Three chimpanzees with a history of conditional and numeric token training spontaneously matched relations between relations under conditions of nondifferential reinforcement. Heretofore, this conceptual ability was demonstrated only in language-trained chimpanzees. The performance levels of the language-naive animals in this study, however, were equivalent to those of a 4th animal—Sarah—whose history included language training and analogical problem solving. There was no evidence that associative factors mediated successful performance in any of the animals. Prior claims of a profound disparity between language-trained and language-naive chimpanzees apparently can be attributed to prior experience with arbitrary tokens consistently associated with abstract relations and not language per se

    Spatial and Temporal Patterns of Small-Scale Mixing in Drake Passage

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    Temperature and salinity profiles obtained with expendable CTD probes throughout Drake Passage between February 2002 and July 2005 are analyzed to estimate turbulent diapycnal eddy diffusivities to a depth of 1000 m. Diffusivity values are inferred from density/temperature inversions and internal wave vertical strain. Both methods reveal the same pattern of spatial variability across Drake Passage; diffusivity estimates from inversions exceed those from vertical strain by a factor of 3 over most of Drake Passage. The Polar Front (PF) separates two dynamically different regions. Strong thermohaline intrusions characterize profiles obtained north of the PF. South of the PF, stratification is determined largely by salinity, and temperature is typically unstably stratified between 100- and 600-m depth. In the upper 400 m, turbulent diapycnal diffusivities are O(10^(−3) m2 s^(−1)) north of the PF but decrease to O(10^(−4) m2 s^(−1)) or smaller south of the PF. Below 400 m diffusivities typically exceed 10^(−4) m^2 s^(−1). Diffusivities decay weakly with depth north of the PF, whereas diffusivities increase with depth and peak near the local temperature maximum south of the PF. The meridional pattern in near-surface mixing corresponds to local maxima and minima of both wind stress and wind stress variance. Near-surface diffusivities are also found to be larger during winter months north of the PF. Wind-driven near-inertial waves, strong mesoscale eddy activity, and double-diffusive convection are suggested as possible factors contributing to observed mixing pattern

    MicroRNA Expression Patterns in Human Anterior Cingulate and Motor Cortex: A Study of Dementia with Lewy Bodies Cases and Controls

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    Overview MicroRNAs (miRNAs) have been implicated in neurodegenerative diseases including Parkinson’s disease and Alzheimer’s disease (AD). Here, we evaluated the expression of miRNAs in anterior cingulate (AC; Brodmann area [BA] 24) and primary motor (MO; BA 4) cortical tissue from aged human brains in the University of Kentucky AD Center autopsy cohort, with a focus on dementia with Lewy bodies (DLB). Methods RNA was isolated from gray matter of brain samples with pathology-defined DLB, AD, AD+DLB, and low-pathology controls, with n=52 cases initially included (n=23 with DLB), all with low (\u3c4hrs) postmortem intervals. RNA was profiled using Exiqon miRNA microarrays. Quantitative PCR for post-hoc replication was performed on separate cases (n=6 controls) and included RNA isolated from gray matter of MO, AC, primary somatosensory (BA 3), and dorsolateral prefrontal (BA 9) cortical regions. Results The miRNA expression patterns differed substantially according to anatomic location: of the relatively highly-expressed miRNAs, 150/481 (31%) showed expression that was different between AC versus MO (at p\u3c0.05 following correction for multiple comparisons), most (79%) with higher expression in MO. A subset of these results were confirmed in qPCR validation focusing on miR-7, miR-153, miR-133b, miR-137, and miR-34a. No significant variation in miRNA expression was detected in association with either neuropathology or sex after correction for multiple comparisons. Conclusion A subset of miRNAs (some previously associated with α-synucleinopathy and/or directly targeting α-synuclein mRNA) were differentially expressed in AC and MO, which may help explain why these brain regions show differences in vulnerability to Lewy body pathology

    Selective Hydrogenation of Furfural in a Proton Exchange Membrane Reactor Using Hybrid Pd/Pd Black on Alumina

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    Invited for this month’s cover picture are the groups of Dr. Peter Pintauro (Vanderbilt University, Tennessee, USA), Dr. Levi Thompson (University of Delaware, Delaware, USA), and Dr. William Tarpeh (Stanford University, California, USA). The cover picture shows the controlled variation of furfural hydrogenation product speciation based on varying cathode formulations of hybrid Pd black and Pd on alumina support. Read the full text of the article at 10.1002/celc.201901314.“The performance of different cathode compositions is evaluated at different current densities (which varies with hydrogen production) in terms of production rate, faradaic efficiency, and selectivity. To isolate the influences of the electrocatalyst in the hybrid catalyst, the performance of electrocatalyst Pd black is evaluated separately. These four variations of the hybrid cathode are investigated to test the hypothesis that the addition of the metal loaded on metal oxide to the electrocatalyst enhances the production rate for hydrogenated products compared to electrodes with only an electrocatalyst…“ Learn more about the story behind the research featured on the front cover in this issue’s Cover Profile. Read the corresponding Article at 10.1002/celc.201901314.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/152714/1/celc201901737.pd

    Collisional Stripping and Disruption of Super-Earths

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    The final stage of planet formation is dominated by collisions between planetary embryos. The dynamics of this stage determine the orbital configuration and the mass and composition of planets in the system. In the solar system, late giant impacts have been proposed for Mercury, Earth, Mars, and Pluto. In the case of Mercury, this giant impact may have significantly altered the bulk composition of the planet. Here we present the results of smoothed particle hydrodynamics simulations of high-velocity (up to ~5 v_esc) collisions between 1 and 10 M_Earth planets of initially terrestrial composition to investigate the end stages of formation of extrasolar super-Earths. As found in previous simulations of collisions between smaller bodies, when collision energies exceed simple merging, giant impacts are divided into two regimes: (1) disruption and (2) hit-and-run (a grazing inelastic collision and projectile escape). Disruption occurs when the impact parameter is near zero, when the projectile mass is small compared to the target, or at extremely high velocities. In the disruption regime, we derive the criteria for catastrophic disruption (when half the total colliding mass is lost), the transition energy between accretion and erosion, and a scaling law for the change in bulk composition (iron-to-silicate ratio) resulting from collisional stripping of a mantle.Comment: 10 pages, 1 table, 4 figures. Accepted for publication in ApJ Letter

    Real-Time Adaptive Event Detection in Astronomical Data Streams

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    A new generation of observational science instruments is dramatically increasing collected data volumes in a range of fields. These instruments include the Square Kilometer Array (SKA), Large Synoptic Survey Telescope (LSST), terrestrial sensor networks, and NASA satellites participating in "decadal survey"' missions. Their unprecedented coverage and sensitivity will likely reveal wholly new categories of unexpected and transient events. Commensal methods passively analyze these data streams, recognizing anomalous events of scientific interest and reacting in real time. Here, the authors report on a case example: Very Long Baseline Array Fast Transients Experiment (V-FASTR), an ongoing commensal experiment at the Very Long Baseline Array (VLBA) that uses online adaptive pattern recognition to search for anomalous fast radio transients. V-FASTR triages a millisecond-resolution stream of data and promotes candidate anomalies for further offline analysis. It tunes detection parameters in real time, injecting synthetic events to continually retrain itself for optimum performance. This self-tuning approach retains sensitivity to weak signals while adapting to changing instrument configurations and noise conditions. The system has operated since July 2011, making it the longest-running real-time commensal radio transient experiment to date

    Extracorporeal membrane oxygenation support after the Fontan operation

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    ObjectiveExtracorporeal membrane oxygenation has been used to support children with cardiac failure after the Fontan operation. Mortality is high, and causes of mortality remain unclear. We evaluated the in-hospital mortality and factors associated with mortality in these patients.MethodsExtracorporeal Life Support Organization registry data on patients requiring extracorporeal membrane oxygenation after the Fontan operation from 1987 to 2009 were retrospectively analyzed. Demographics and extracorporeal membrane oxygenation data were compared for survivors and nonsurvivors. A multivariable logistic regression model was used to identify factors associated with mortality.ResultsOf 230 patients, 81 (35%) survived to hospital discharge. Cardiopulmonary resuscitation was more frequent (34% vs 17%, P = .04), and median fraction of inspired oxygen concentration was higher (1 [confidence interval, 0.9–1.0] vs 0.9 [confidence interval, 0.8–1.0], P = .03) before extracorporeal membrane oxygenation in nonsurvivors compared with survivors. Extracorporeal membrane oxygenation duration and incidence of complications, including surgical bleeding, neurologic injury, renal failure, inotrope use on extracorporeal membrane oxygenation, and bloodstream infection, were higher in nonsurvivors compared with survivors (P < .05 for all). In a multivariable model, neurologic injury (odds ratio, 5.18; 95% confidence interval, 1.97–13.61), surgical bleeding (odds ratio, 2.36; 95% confidence interval, 1.22–4.56), and renal failure (odds ratio, 2.81; 95% confidence interval, 1.41–5.59) increased mortality. Extracorporeal membrane oxygenation duration of more than 65 hours to 119 hours (odds ratio, 0.33; 95% confidence interval, 0.14–0.76) was associated with decreased mortality.ConclusionsCardiac failure requiring extracorporeal membrane oxygenation after the Fontan operation is associated with high mortality. Complications during extracorporeal membrane oxygenation support increase mortality odds. Prompt correction of surgical bleeding when possible may improve survival
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