Kinematics of planet-host stars and their relation with dynamical streams in the solar neighbourhood

We present a detailed study on the kinematics of metal-rich stars with and without planets, and their relation with the Hyades, Sirius and Hercules dynamical streams in the solar neighbourhood. Accurate kinematics have been derived for all the stars belonging to the CORALIE planet search survey. We used precise radial velocity measurements and CCF parameters from the CORALIE database, and parallaxes, photometry and proper motions from the HIPPARCOS and Tycho-2 catalogues. The location of stars with planets in the thin or thick discs has been analysed using both kinematic and chemical constraints. We compare the kinematic behaviour of known planet-host stars to the remaining targets belonging to the volume-limited sample, in particular to its metal-rich population. The high average metallicity of the Hyades stream is confirmed. The planet-host targets show a kinematic behaviour similar to that of the metal-rich comparison subsample, rather than to that of the comparison sample as a whole, thus supporting a primordial origin for the metal excess observed in stars with known planetary companions. According to the scenarios proposed as an explanation for the dynamical streams, systems with giant planets could have formed more easily in metal-rich inner Galactic regions and then been brought into the solar neighbourhood by dynamical streams.Comment: 14 pages, 12 figures, accepted for publication in A&A (28 August 2006

Life-Threatening Cardiac Manifestations of Pheochromocytoma

Pheochromocytoma is a catecholamine-secreting tumor of the adrenal glands, usually with benign manifestations, whose typical clinical presentation includes the triad of headache, palpitations and diaphoresis. However, a wide range of signs and symptoms may be present. In the cardiovascular system, the most common signs are labile hypertension and sinus tachycardia. Systolic heart failure and ST-segment deviations mimicking myocardial infarction have also been reported, as well as QT interval prolongation and, rarely, ventricular tachycardia. We describe a challenging diagnosis of pheochromocytoma with many cardiovascular manifestations, which could have been missed due to the absence of typical symptoms

Quasi-normal modes of the scalar hairy black hole

We calculate QNMs of the scalar hairy black hole in the AdS background using Horowitz-Hubeny method for the potential that is not known in analytical form. For some black hole parameters we found pure imaginary frequencies. Increasing of the scalar field mass does not cause the imaginary part to vanish, it reaches some minimum and then increases, thus in the case under consideration the infinitely long living modes (quasi-resonances) do not appear.Comment: 17 pages, 17 figures, LaTe

IMPACTO AMBIENTAL NA IMPLANTAÇÃO DE AEROPORTOS

Os aeroportos são, caracterizados por serem estruturas com grande impacto modificador do meio ambiente. O presente trabalho apresenta os principais impactos que a implantação de aeroportos, bem como ações mitigadoras, que visam reduzir ou amenizar as conseqüências desses impactos. A questão ambiental passou a ser um fator de extrema importância na tomada de decisões para a sua autorização. Desta forma, ações mitigadoras tem auxiliado à combater os impactos negativos tanto de caráter local, como global, bastando aplicar as leis e normatizações vigentes no Brasil

Omega-3 intake is associated with attenuated inflammatory response and cardiac remodeling after myocardial infarction

Myocardial infarction (MI) elicits an intense acute inflammatory response that is essential for cardiac repair. However, an excessive inflammatory response also favors myocardial apoptosis, cardiac remodeling, and cardiovascular mortality. Omega-3 polyunsaturated fatty acids (-3) bear anti-inflammatory effects, which may mitigate the inflammatory response during MI. This study investigated whether -3 intake is associated with attenuation of the MI-related inflammatory response and cardiac remodeling. ST-elevation MI (STEMI) patients (n=421) underwent clinical, biochemical, nutritional, 3D echocardiogram, Cardiac Magnetic Resonance imaging (CMRi) at 30 days and 3D echocardiogram imaging at six months after the MI. Blood tests were performed at day one (D1) and day five (D5) of hospitalization. Changes in inflammatory markers (D5-D1) were calculated. A validated food frequency questionnaire estimated the nutritional consumption and -3 intake in the last 3months before admission. The intake of -3 below the median (<1.7g/day) was associated with a short-term increase in hs-C-reactive protein [OR:1.96(1.24-3.10); p=0.004], Interleukin-2 [OR:2.46(1.20-5.04); p=0.014], brain-type natriuretic peptide [OR:2.66(1.30-5.44); p=0.007], left-ventricle end-diastolic volume [OR:5.12(1.11-23.52)]; p=0.036] and decreases in left-ventricle ejection fraction [OR:2.86(1.47-6.88); p=0.017] after adjustment for covariates. No differences were observed in the extension of infarcted mass obtained by CMRi. These findings suggest that a reduced daily intake of -3 may intensify outcome-determining mechanisms after STEMI, such as acute inflammatory response and late left ventricular remodeling.18CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ308550/2010-

Complete mitochondrial genomes of the freshwater mussels Amblema plicata (Say, 1817), Pleurobema oviforme (Conrad, 1834), and Popenaias popeii (Lea, 1857) (Bivalvia: Unionidae: Ambleminae)

Freshwater mussels are a critically imperiled group of mollusks that play key ecological roles and provide important services to humans. The Ambleminae is the only subfamily of these mussels, endemic to North America. Complete mitogenomes have only been sequenced for two of five tribes of the subfamily. Pleurobema oviforme, Amblema plicata, and Popenaias popeii each belong to tribes Pleurobemini, Amblemini, and Popenaidini, respectively, and have not had published mitogenomes. Thus, this study aims to present the complete mitogenomes for these species, to provide a phylogeny of the Ambleminae and confirm the gene arrangements with representation from each of its tribes. The newly sequenced mitogenomes range from 15,852 to 15,993 nucleotides, are composed of 13 PCGs, 22 tRNAs, and two rRNAs and all share the same (UF1) gene order.This work was supported by Portuguese Foundation for Science and Technology (FCT) [grant number ConBioMics/BI-Lic/2019-037 (JTT), grant number SFRH/BD/137935/2018 (AGS)]; COMPETE 2020, Portugal 2020 and the European Union through the ERDF, and by Portuguese Foundation for Science and Technology (FCT) through national funds [UID/Multi/04423/2019] under project ConBiomics: the missing approach for the Conservation of Bivalves Project, and [project number NORTE-01- 0145-FEDER-030286]. Fieldwork in Texas was funded by the U.S. Fish and Wildlife Service, and Texas Parks and Wildlife Department (TPWD) as a Joint Traditional Section 6 Project 407348.info:eu-repo/semantics/publishedVersio

A narrative review of preschool teacher burnout

Preschool teacher burnout is a significant concern, including the lack of professionals in the field, high turnover rates, and understaffed facilities and schools. Burnout in general, has increased during the COVID-19 pandemic as preschool teacher stress is at an all-time high. Preschool teachers are an understudied population exiting the workforce at a high rate, and a lot of the focus is on attrition. The majority of literature involving teachers has focused on the K-12 sector, or the higher education population, indicating a significant need to study the pre-school population more in-depth. This narrative serves as a review of the literature in journals and educational organizational sites on burnout among early childhood educators over the last ten years. The current review of literature focused on poor wages, work-family conflict, and lack of support in the classroom. Future research should assess burnout and determine ways to counter stress among this population. The literature on burnout in the preschool and early childhood education professions are scarce, and further research is needed to understand how to combat burnout in this population

High incidence of acquiring methicillin-resistant <i>Staphylococcus aureus</i> in Brazilian children with Atopic Dermatitis and associated risk factors

BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) colonization in Atopic Dermatitis (AD) patients can contribute to worsening their clinical condition. OBJECTIVE: A cohort study was carried out to determine the incidence of MRSA acquisition and its risk factors in AD children. METHODS: Patients with AD (2 months-14 years old) were followed up for about 1 year at a reference center for AD treatment in Rio de Janeiro, Brazil, from September 2011 to February 2014. Nasal swabs from patients and contacts were collected every 2 months. The SCORAD system assessed the severity of the AD. S. aureus isolates were evaluated to determine the methicillin resistance and the clonal lineages. RESULTS: Among 117 AD patients, 97 (82.9%) were already colonized with S. aureus and 26 (22.2%) had MRSA at the first evaluation. The incidence of MRSA acquisition in the cohort study was 27.47% (n = 25). The SCORAD assessments were: mild (46.15%), moderate (37.36%) or severe (16.48%). Risk factors were: colonized MRSA contacts (HR = 2.27; 95% CI: 1.16-7.54), use of cyclosporine (HR = 5.84; 95% CI: 1.70-19.98), moderate or severe AD (HR = 3.26; 95% CI: 1.13-9.37). Protective factors were: availability of running water (HR = 0.21; 95% CI: 0.049-0.96) and use of antihistamines (HR = 0.21; 95% IC: 0.64-0.75). MRSA isolates carried the SCCmec type IV and most of them were typed as USA800/ST5. CONCLUSIONS: The high incidence of MRSA acquisition found among AD patients and the risk factors associated show that an effective surveillance of MRSA colonization in these patients is needed

Maternal periodontal disease as a factor associated with low birth weight

OBJETIVO: Estudos recentes têm apresentado evidências de que a doença periodontal em gestantes pode ser um dos determinantes do baixo peso ao nascer. Realizou-se estudo para verificar a existência de associação entre doença periodontal materna e baixo peso ao nascer. MÉTODOS: Estudo do tipo caso-controle com 302 mulheres, sendo 102 mães de nascidos vivos de baixo peso (grupo caso) e 200 mães de nascidos vivos com peso normal (grupo controle). A existência de associação entre doença periodontal e baixo peso ao nascer foi avaliada mediante modelo multivariado de regressão logística, considerando outros fatores de risco para o baixo peso. RESULTADOS: Ambos os grupos de mães eram comparáveis no que se refere a idade, altura, peso pré-gestacional, tabagismo, alcoolismo, doenças prévias, estado civil, situação socioeconômica, número de escovações e uso de fio dental, número de refeições diárias, e visitas ao dentista. A doença periodontal foi diagnosticada em 57,8% das mães do grupo caso e 39,0% do grupo controle. A análise de regressão logística indicou associação positiva entre doença periodontal e baixo peso ao nascer (ORbruto=2,15; IC 95%: 1,32-3,48), especialmente entre as mães com escolaridade menor ou igual a quatro anos (ORajustada=3,98; IC 95%: 1,58-10,10). CONCLUSÕES: A doença periodontal é um possível fator de risco para o baixo peso ao nascer.OBJECTIVE: Recent studies have presented evidence that periodontal disease in pregnant women may be a determining factor for low birth weight. The present investigation was carried out to verify whether or not there is an association between maternal periodontal disease and low birth weight. METHODS: This was a case-control study on 302 women, of whom 102 were the mothers of live newborns of low weight (case group) and 200 were the mothers of live newborns of normal birth weight (control group). The existence of an association between periodontal disease and low birth weight was evaluated by means of a multivariate logistic regression model that considered other risk factors for low weight. RESULTS: The two groups were comparable with regard to age, height, pre-gestational weight, smoking, alcohol use, previous diseases, marital status, socioeconomic status, frequency of tooth-brushing and use of dental floss, number of meals per day and visits to the dentist. Periodontal disease was diagnosed in 57.8% of the mothers in the case group and 39.0% in the control group. Logistic regression analysis indicated a positive association between periodontal disease and low birth weight (unadjusted OR=2.15; 95% CI: 1.32-3.48), especially among the mothers with schooling of less than or equal to four years (ORadjusted=3.98; 95% CI: 1.58-10.10). CONCLUSIONS: Periodontal disease is a possible risk factor for low birth weight

A new transdermal drug delivery system containing hydroquinone

Hydroquinone (HQ) is a drug reported to possess manifold biological activities. HQ is highly unstable into various topical vehicles, presenting low topical bioavailability and a relevant level of toxicity. The Pluronic® Lecithin Organogel (PLOme) is a phospholipidic microemulsion designed for transdermal purposes. The aim of this work was therefore to incorporate HQ into PLOme. We evaluated the stability, the kinetic profile and the antimicrobial activity of HQ- incorporated PLOme. No relevant pH variation was observed. Long-term stability test showed an HQ degradation which led to a short shelf life. HQ permeation rate obtained was lower from PLOme than from a gel matrix. Free and PLOme-encapsulated hydroquinone showed to have a great in vitro inhibitory potential against of S. aureus strains. The encapsulation of HQ due its unstable characteristics could be an alternative to optimize its therapeutic usage, and so further investigation is required on this pharmaceutical form before commercialization.Colegio de Farmacéuticos de la Provincia de Buenos Aire