Características da Evidenciação da Fase de Pesquisa e Desenvolvimento de Ativos Intangíveis nas Companhias de Capital Aberto Brasileiras

Esta pesquisa objetivou identificar as características da evidenciação da fase de pesquisa e desenvolvimento de ativos intangíveis nas companhias de capital aberto brasileiras. Para alcançar o objetivo proposto, utilizou-se uma Lista de Verificação com base nos requisitos estabelecidos pelo CPC 04 (R1), com uma amostra de 36 companhias de capital aberto. Os resultados demonstram que a média do nível de evidenciação apresentou um resultado de 24,31%. Percebe-se que as companhias que compuseram a amostra deste estudo pouco divulgaram informações a respeito dos detalhamentos e composições dos gastos com pesquisa e desenvolvimento. Destacam-se os seguintes pontos: i) qual intangível as companhias esperam que sejam desenvolvidos a partir das pesquisas realizadas; ii) como o desenvolvimento dos intangíveis irá gerar benefícios econômicos futuros; e iii) evidenciação da separação dos gastos com pesquisa e desenvolvimento. Constata-se que a evidenciação da fase de pesquisa e desenvolvimento de ativos intangíveis ainda é baixa no Brasil

Physicochemical characterization, microbiological quality and safety, and pharmacological potential of Hancornia speciosa Gomes

Hancornia speciosa Gomes is a fruit tree, commonly known as the mangaba tree, which is widespread throughout Brazil. The leaves of this plant are used in traditional medicine for medicinal purposes. Thus, the objective of this study was to perform a physicochemical characterization, identify the lipophilic antioxidants and fatty acids, and determine the microbiological quality and safety of H. speciosa leaves. In addition, the antioxidant, antimutagenic, and inhibitory activities of the ethanolic extract of H. speciosa leaves (EEHS) against enzymes related to neurodegenerative diseases, inflammation, obesity, and diabetes were investigated. Furthermore, this study aimed at assessing the in vivo effects of the EEHS on the glycemia of normoglycemic and diabetic Wistar rats. Physicochemical characterization was performed by colorimetry and gas-liquid chromatography with flame ionization detection (GC-FID). The total number of colonies of aerobic mesophiles, molds, and yeasts was determined. The total coliforms and Escherichia coli were counted using the SimPlates kit, and sulphite-reducing Clostridium spores were quantified using the sulphite-polymyxin-sulfadiazine agar method. Salmonella spp. were detected using the 1-2 Test. The antioxidant activity of the EEHS was measured by its inhibition of 2,2′-azobis(2-amidinopropane) dihydrochloride- (AAPH-) induced oxidative hemolysis of human erythrocytes. The antimutagenic activity was determined using the Ames test. The acetylcholinesterase, butyrylcholinesterase, tyrosinase, hyaluronidase, lipase, α-amylase, and α-glycosidase enzyme-inhibiting activities were assessed and compared with commercial controls. The in vivo effects of the EEHS were assessed using the oral glucose tolerance test in normoglycemic Wistar rats and measuring the blood glucose levels in diabetic rats. The results demonstrated physical-chemical parameters of microbiological quality and safety in the leaves of H. speciosa, as well as antioxidant and antimutagenic activities and inhibition of enzymes related to neurodegenerative diseases, inflammation, obesity, and diabetes. In in vivo assays, it was shown that the normoglycemic rats challenged with glucose overload show significantly decreased blood glucose levels when treated with the EEHS. Taken together, the results ensure the microbiological quality and safety as well as showing the contents of carotenoids and polyunsaturated fatty acids of H. speciosa leaves. Additionally, the antioxidant, antimutagenic, anti-inflammatory, anti-Alzheimer’s disease, anti-Parkinson’s disease, antiobesity, and antihyperglycemic activities of the EEHS were demonstrated.This work was supported by grants from Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul (FUNDECT), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Universidade Federal da Grande Dourados (UFGD), and PRODER (24.073–A, Portugal).info:eu-repo/semantics/publishedVersio

PRODUÇÃO DE CONHECIMENTO: PESQUISA E CURRÍCULO

Tal artigo constitui-se de uma pesquisa bibliográfica, onde utilizamos autores que tratam o tema “Pesquisa dentro da sala de aula”, nos anos iniciais do ensino básico. Abordamos aqui como se pode estar trazendo a pesquisa para o dia-a-dia do aluno. Como o professor pode instigar seus estudantes a querer pesquisar, e também da importância de formar alunos pesquisadores, e por sua vez, questionadores.Palavra-Chave: Pesquisa, Educação, Aprendizagem

BRIEF REVIEW ON THE MEDICINAL USES AND ANTIMICROBIAL ACTIVITY OF DIFFERENT PARTS OF SCHINUS TEREBINTHIFOLIUS RADDI

Populations all over the world make use of medicinal plants to treat health problems. Plants are pertaining to the Anacardiaceae family which largely occur throughout Brazil, such as the Schinus terenbithifolius Raddi species, commonly known as aroeira, have been adopted in Brazilian folk medicine for the treatment of countless diseases and have also been indicated and studied as an antimicrobial agent. Several parts of the plant such as the leaves, the fruits and barks have their antimicrobial activity attested. The indication for the part of the plant to be used as an antimicrobial for folk medicine is yet to be made clear. Several parts are used and in some cases, for similar ends. There are no conclusive studies that describe the difference in antimicrobial action from each plant part. In this review, we investigated the antimicrobial activity of the Schinus terenbithifolius Raddi and then the information available in the literature was organized. The antimicrobial activity described in scientific publications according to the plant parts applied and the type of extract acquired in order to determine such activity

Diversity, chemical constituents and biological activities of endophytic fungi isolated from Schinus terebinthifolius raddi

Schinus terebinthifolius Raddi is a medicinal plant widely used for the treatment of various diseases. The secondary metabolites responsible for the pharmacological properties can be produced directly by the plant or by endophytic fungi. The objective of this study was to evaluate the diversity of endophytic fungi of di erent parts of S. terebinthifolius and to identify chemical compounds produced by endophytes and their antioxidant and antibacterial activities. For this, fruits, stem bark and roots were dried, ground and placed in fungal growth medium. The selected endophytes were grown and subjected to extraction with ethyl acetate. DPPH, FRAP, -carotene bleaching and antimicrobial assays were performed. The phylogenetic tree was elaborated, encompassing 15 di erent species. The fungal extracts showed hydroxybenzoic acids and 1-dodecanol as predominant compounds. All fungal extracts exhibited antioxidant activity. The fungal extracts exhibited bactericidal and bacteriostatic activities against Gram-positive and Gram-negative bacterial ATCC strains and against methicillin-resistant nosocomial bacteria. Among the 10 endophytic fungi evaluated, the extract of the fungus Ochrocladosporium elatum showed higher phenolic content and exhibited higher antioxidant and antibacterial activities in all tests. Together, the results increase the known diversity of S. terebinthifolius endophytic fungi, secondary metabolites produced and their antioxidant and antibacterial activities.Thisworkwas supported by grants fromFoundation to Support to Fundação deApoio aoDesenvolvimento do Ensino, Ciência e Tecnologia do Estado deMato Grosso do Sul (FUNDECT), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq).info:eu-repo/semantics/publishedVersio

Quality and microbiological safety and antifungal activity of Hancornia Speciosa Gomes (Apocynaceae).

The aim of this study was to evaluate the quality and microbiological safety and antifungal activity of the ethanolic extract of the leaves of Hancomia Gomes (EEHS), a Brazilian fruit tree popularly known mangabeira .info:eu-repo/semantics/publishedVersio

Emergências obstétricas e acolhimento das usuárias na classificação de risco

The present study aims to reflect on the importance of welcoming to carry out humanized and responsible care. This is an integrative review carried out in three databases: Virtual Health Library, Scientific Electronic Library Online and PubMed. The search was carried out by pre-established descriptors and full texts from the last five years were used, in Portuguese, English and Spanish. Through an exhaustive reading of these it was possible to realize that the risk classification in the Urgency and Emergency care is of great importance, often avoiding the death of the mother and fetus. Also considering the theme of reception during the Sars-CoV-2 virus pandemic, it was possible to realize that the use of care protocols informed by the World Health Organization is essential to avoid contagion and identify users who are infected with the virus of COVID-19.O presente estudo tem como objetivo refletir sobre a importância do acolhimento para realizar um atendimento humanizado e responsável. Trata-se de uma revisão integrativa realizada em três bases de dados: Biblioteca Virtual em Saúde, Scientific Electronic Library Online e PubMed. A busca ocorreu por descritores preestabelecidos e foram utilizados textos completos dos últimos cinco anos, nas línguas portuguesa, inglesa e espanhola. Através da leitura exaustiva destes foi possível perceber que a classificação de risco nos atendimentos de Urgência e Emergência é de grande importância, evitando muitas vezes a morte da mãe e feto. Considerando também a temática do acolhimento durante a pandemia do vírus Sars-CoV-2, foi possível perceber que é imprescindível o uso de protocolos de atendimentos informados pela Organização Mundial da Saúde para evitar o contágio e identificar as usuárias que estejam infectadas com o vírus da COVID-19

Conservation of wild mushrooms through electron beam irradiation

The high perishability is a characteristic of the mushrooms consumed in fresh. Therefore, it is mandatory the application of effective conservation technologies to preserve and protect their chemical composition and nutritional value. Drying processes are widely used, but do not avoid the development of bacteria and fungi which have the ability to survive for long periods of time in dry foods, causing the loss of some nutrients and leading to food browning and oxidation of lipids and vitamins [1]. Irradiation appears as an alternative to food preservation assuring and maintaining its quality [2]. In this work, the effects of electron beam irradiation and storage time on nutritional and chemical parameters of wild samples of Macrolepiota procera (Scop.) Singer, previously submitted to a drying process (oven at 30 ºC), were assessed. The wild mushroom samples were collected in Trás-os-Montes; electron beam irradiation (doses 0.5, 1 and 6 kGy) was carried out in the INCT- Institute of Nuclear Chemistry and Technology in Warsaw, Poland and the analyses were performed over the storage period (0, 6 and 12 months). The results were compared with a control (non-irradiated samples). The nutritional value was determined according to the official procedures of food analysis, while the profiles of fatty acids, tocopherols, mono and oligosaccharides were obtained by chromatographic techniques [1]. The irradiation showed a better capacity to maintain the nutritional and chemical profile, in comparison with the storage time. Effectively, the storage time had a significant effect in all parameters, but fatty acids undergone significant changes both with irradiation doses and storage time. Electron beam irradiation can be considered a suitable technique for conservation of mushrooms for long periods of time, attenuating the changes caused by the drying treatment.The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) and FEDER under Programme PT2020 for financial support to CIMO (UID/AGR/00690/2013), A. Fernandes (SFRH/BPD/114753/2016) and J.C.M. Barreira contract.info:eu-repo/semantics/publishedVersio