101 research outputs found
Réponse impulsionnelle inverse paramétrique. Une approche basée sur la réduction de modèles et des excitations aléatoires
Fast simulation of the pantograph-catenary dynamic interaction
Simulation of the pantograph-catenary dynamic interaction has now become a useful tool for designing and optimizing the system. In order to perform accurate simulations, including system non-linearities, the Finite Element Method is commonly employed combined with a time integration scheme, even though the computational time required may be longer than with the use of other simpler approaches. In this paper we propose a two-stage methodology (Offline/Online) which notably reduces the computational cost without any loss in accuracy and makes it possible to successfully carry out very efficient optimizations or even Hardware in the Loop simulations with real-time requirements.The authors would like to acknowledge the financial support received from the FPU program offered by the Ministerio de Educacion, Cultura y Deporte under grant number (FPU13/04191), and also funding from the Universitat Politecnica de Valencia and the Generalitat Valenciana (PROMETEO/2016/007).Gregori Verdú, S.; Tur Valiente, M.; Nadal Soriano, E.; Aguado, J.; Fuenmayor Fernández, FJ.; Chinesta, F. (2017). Fast simulation of the pantograph-catenary dynamic interaction. Finite Elements in Analysis and Design. 129:1-13. https://doi.org/10.1016/j.finel.2017.01.007S11312
Critical behavior of the frustrated antiferromagnetic six-state clock model on a triangular lattice
We study the anti-ferromagnetic six-state clock model with nearest neighbor
interactions on a triangular lattice with extensive Monte-Carlo simulations. We
find clear indications of two phase transitions at two different temperatures:
Below a chirality order sets in and by a thorough finite size scaling
analysis of the specific heat and the chirality correlation length we show that
this transition is in the Ising universality class (with a non-vanishing
chirality order parameter below ). At the spin-spin
correlation length as well as the spin susceptibility diverges according to a
Kosterlitz-Thouless (KT) form and spin correlations decay algebraically below
. We compare our results to recent x-ray diffraction experiments on the
orientational ordering of CFBr monolayers physisorbed on graphite. We argue
that the six-state clock model describes the universal feature of the phase
transition in the experimental system and that the orientational ordering
belongs to the KT universality class.Comment: 8 pages, 9 figure
Chiral phase transitions: focus driven critical behavior in systems with planar and vector ordering
The fixed point that governs the critical behavior of magnets described by
the -vector chiral model under the physical values of () is
shown to be a stable focus both in two and three dimensions. Robust evidence in
favor of this conclusion is obtained within the five-loop and six-loop
renormalization-group analysis in fixed dimension. The spiral-like approach of
the chiral fixed point results in unusual crossover and near-critical regimes
that may imitate varying critical exponents seen in physical and computer
experiments.Comment: 4 pages, 5 figures. Discussion enlarge
Thermal excitations of frustated XY spins in two dimensions
We present a new variational approach to the study of phase transitions in
frustrated 2D XY models. In the spirit of Villain's approach for the
ferromagnetic case we divide thermal excitations into a low temperature long
wavelength part (LW) and a high temperature short wavelength part (SW). In the
present work we mainly deal with LW excitations and we explicitly consider the
cases of the fully frustrated triangular (FFTXY) and square ( FFSQXY) XY
models. The novel aspect of our method is that it preserves the coupling
between phase (spin angles) and chiral degrees of freedom. LW fluctuations
consist of coupled phase and chiral excitations. As a result, we find that for
frustrated systems the effective interactions between phase variables is long
range and oscillatory in contrast to the unfrustrated problem. Using Monte
Carlo (MC) simulations we show that our analytical calculations produce
accurate results at all temperature ; this is seen at low in the spin
wave stiffness constant and in the staggered chirality; this is also the case
near : transitions are driven by the SW part associated with domain walls
and vortices, but the coupling between phase and chiral variables is still
relevant in the critical region. In that regime our analytical results yield
the correct dependence for bare couplings (given by the LW fluctuations)
such as the Coulomb gas temperature of the frustrated XY models . In
particular we find that tracks chiral rather than phase fluctuations.
Our results provides support for a single phase transition scenario in the
FFTXY and FFSQXY models.Comment: 32 pages, RevTex, 11 eps figures available upon request, article to
appear in Phys. Rev.
Tele-rehabilitation versus local rehabilitation therapies assisted by robotic devices: a pilot study with patients
The present study aims to evaluate the advantages of a master-slave robotic rehabilitation therapy in which the patient is assisted in real-time by a therapist. We have also explored if this type of strategy is applicable in a tele-rehabilitation environment. A pilot study has been carried out involving 10 patients who have performed a point-to-point rehabilitation exercise supported by three assistance modalities: fixed assistance (without therapist interaction), local therapist assistance, and remote therapist assistance in a simulated tele-rehabiliation scenario. The rehabilitation exercise will be performed using an upper-limb rehabilitation robotic device that assists the patients through force fields. The results suggest that the assistance provided by the therapist is better adapted to patient needs than fixed assistance mode. Therefore, it maximizes the patient's level of effort, which is an important aspect to improve the rehabilitation outcomes. We have also seen that in a tele-rehabilitation environment it is more difficult to assess when to assist the patient than locally. However, the assistance suits patients better than the fixed assistance mode
Reação de cultivares e linhagens de feijoeiro em relação a Meloidogyne javanica e Fusarium oxysporum f. sp. phaseoli
Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial
Background:
Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly albiglutide in type 2 diabetes are unknown. We aimed to determine the safety and efficacy of albiglutide in preventing cardiovascular death, myocardial infarction, or stroke.
Methods:
We did a double-blind, randomised, placebo-controlled trial in 610 sites across 28 countries. We randomly assigned patients aged 40 years and older with type 2 diabetes and cardiovascular disease (at a 1:1 ratio) to groups that either received a subcutaneous injection of albiglutide (30–50 mg, based on glycaemic response and tolerability) or of a matched volume of placebo once a week, in addition to their standard care. Investigators used an interactive voice or web response system to obtain treatment assignment, and patients and all study investigators were masked to their treatment allocation. We hypothesised that albiglutide would be non-inferior to placebo for the primary outcome of the first occurrence of cardiovascular death, myocardial infarction, or stroke, which was assessed in the intention-to-treat population. If non-inferiority was confirmed by an upper limit of the 95% CI for a hazard ratio of less than 1·30, closed testing for superiority was prespecified. This study is registered with ClinicalTrials.gov, number NCT02465515.
Findings:
Patients were screened between July 1, 2015, and Nov 24, 2016. 10 793 patients were screened and 9463 participants were enrolled and randomly assigned to groups: 4731 patients were assigned to receive albiglutide and 4732 patients to receive placebo. On Nov 8, 2017, it was determined that 611 primary endpoints and a median follow-up of at least 1·5 years had accrued, and participants returned for a final visit and discontinuation from study treatment; the last patient visit was on March 12, 2018. These 9463 patients, the intention-to-treat population, were evaluated for a median duration of 1·6 years and were assessed for the primary outcome. The primary composite outcome occurred in 338 (7%) of 4731 patients at an incidence rate of 4·6 events per 100 person-years in the albiglutide group and in 428 (9%) of 4732 patients at an incidence rate of 5·9 events per 100 person-years in the placebo group (hazard ratio 0·78, 95% CI 0·68–0·90), which indicated that albiglutide was superior to placebo (p<0·0001 for non-inferiority; p=0·0006 for superiority). The incidence of acute pancreatitis (ten patients in the albiglutide group and seven patients in the placebo group), pancreatic cancer (six patients in the albiglutide group and five patients in the placebo group), medullary thyroid carcinoma (zero patients in both groups), and other serious adverse events did not differ between the two groups. There were three (<1%) deaths in the placebo group that were assessed by investigators, who were masked to study drug assignment, to be treatment-related and two (<1%) deaths in the albiglutide group.
Interpretation:
In patients with type 2 diabetes and cardiovascular disease, albiglutide was superior to placebo with respect to major adverse cardiovascular events. Evidence-based glucagon-like peptide 1 receptor agonists should therefore be considered as part of a comprehensive strategy to reduce the risk of cardiovascular events in patients with type 2 diabetes.
Funding:
GlaxoSmithKline
Search for gravitational waves from Scorpius X-1 in the second Advanced LIGO observing run with an improved hidden Markov model
We present results from a semicoherent search for continuous gravitational waves from the low-mass x-ray binary Scorpius X-1, using a hidden Markov model (HMM) to track spin wandering. This search improves on previous HMM-based searches of LIGO data by using an improved frequency domain matched filter, the J-statistic, and by analyzing data from Advanced LIGO's second observing run. In the frequency range searched, from 60 to 650 Hz, we find no evidence of gravitational radiation. At 194.6 Hz, the most sensitive search frequency, we report an upper limit on gravitational wave strain (at 95% confidence) of h095%=3.47×10-25 when marginalizing over source inclination angle. This is the most sensitive search for Scorpius X-1, to date, that is specifically designed to be robust in the presence of spin wandering. © 2019 American Physical Society
Erratum: "A Gravitational-wave Measurement of the Hubble Constant Following the Second Observing Run of Advanced LIGO and Virgo" (2021, ApJ, 909, 218)
[no abstract available
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