14 research outputs found
Disparities in Clinical Research Participation: Motivators, Barriers and Facilitators of Primary Care Patients
- Author
- Publication venue
- LVHN Scholarly Works
- Publication date
- 24/10/2015
- Field of study
Participation in Clinical Research: A Thorough Explanation in Their Own Language Helps Family Medicine Patients Decide.
- Author
- Publication venue
- LVHN Scholarly Works
- Publication date
- 29/06/2015
- Field of study
Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials.
- Author
- Aalborg University Hospital
- Abayomi Akin
- Abduljalil Manal
- Abdulrahman Abdulkarim
- Acosta-Ampudia Yeny
- Aguilar-Guisado Manuela
- Al-Beidh Farah
- Alejandria Marissa M.
- Alfonso Rachelle N.
- Ali Mohammad
- AlQahtani Manaf
- AlZamrooni Alaa
- Anaya Juan-Manuel
- Ang Mark Angelo C.
- Aomar Ismael F.
- Argumanis Luis E.
- Averyanov Alexander
- Axfors Cathrine
- Baklaushev Vladimir P.
- Balionis Olga
- Benfield Thomas
- Berry Scott
- Birocco Nadia
- Bonifacio Lynn B.
- Bowen Asha C.
- Bown Abbie
- Cabello-Gutierrez Carlos
- Camacho Bernardo
- Camacho-Ortiz Adrian
- Campbell-Lee Sally
- Cao Damon H.
- Cardesa Ana
- Carnate Jose M.
- Castillo German Jr. J.
- Cavallo Rossana
- Chowdhury Fazle R.
- Chowdhury Forhad U. H.
- Ciccone Giovannino
- Cingolani Antonella
- Climacosa Fresthel Monica M.
- Compernolle Veerle
- Cortez Carlo Francisco N.
- Costa Neto Abel
- D?Antico Sergio
- D?az Ponce-Medrano Juan A.
- D?az-Coronado Juan C.
- Daly James
- Danielle Franca
- Davis Joshua S.
- De Rosa Francesco Giuseppe
- Denholm Justin T.
- Denkinger Claudia M.
- Department of Clinical Medicine
- Department of Infectious Diseases
- Desmecht Daniel
- Donneau Anne-Fran?oise
- Dumagay Teresita E.
- Dunachie Susanna
- Dungog Cecile C.
- Erinoso Olufemi
- Escasa Ivy Mae S.
- Estcourt Lise J.
- Evans Amy
- Evasan Agnes L. M.
- Fareli Christian J.
- Fernandez-Sanchez Veronica
- G?mez-Almaguer David
- Galassi Claudia
- Gallo Juan E.
- Garcia Jesus A.
- Garcia Patricia J.
- Garcia Patricia L.
- Garigliany Mutien
- Garza-Gonzalez Elvira
- Gauiran Deonne Thaddeus V.
- Gaviria Garc?a Paula A.
- Giron-Gonzalez Jose-Antonio
- Goodman Steven N.
- Gordon Anthony C.
- Gothot Andr?
- Grass Guaqueta Jeser Santiago
- Green Cameron
- Grimaldi David
- Haber Noah A.
- Hammond Naomi E.
- Harvala Heli
- Hemkens Lars G.
- Heralde Francisco M.
- Herrick Jesica
- Higgins Alisa M.
- Hills Thomas E.
- Hines Jennifer
- Holm Karin
- Hoque Ashraful
- Hospital Universitario de Jerez de la Frontera
- Hoste Eric
- Ignacio Jose M.
- Ioannidis John P. A.
- Ivanov Alexander V.
- Janiaud Perrine
- Janssen Maike
- Jennings Jeffrey H.
- Jha Vivekanand
- Khanna Nina
- King Ruby Anne N.
- Kjeldsen-Kragh Jens
- Klenerman Paul
- Klinik Medicin og Akut
- Kotecha Aditya
- Krapp Fiorella
- L?pez-C?rdenas Salvador
- L?pez-Robles Concepci?n
- Labanca Luciana
- Laing Emma
- Landin-Olsson Mona
- Laterre Pierre-Fran?ois
- Lim Jodor
- Lim Lyn-Li
- Ljungquist Oskar
- Llaca-D?az Jorge M.
- Lopez-Plaza Ileana
- Lucero Josephine Anne C.
- Lundgren Maria
- M?ller-Tidow Carsten
- Mac?as Juan
- Maganito Sandy C.
- Malundo Anna Flor G.
- Manrique Rub?n D.
- Manzini Paola M.
- Marcos Miguel
- Marquez Ignacio
- Mart?nez-Marcos Francisco Javier
- Mata Ana M.
- McArthur Colin J.
- McQuilten Zoe K.
- McVerry Bryan J.
- Menon David K.
- Meyfroidt Geert
- Mirasol Ma. Angelina L.
- Misset Beno?t
- Moher David
- Molton James S.
- Mondragon Alric V.
- Monsalve Diana M.
- Moradi Choghakabodi Parastoo
- Morpeth Susan C.
- Mouncey Paul R.
- Moutschen Michel
- Murphy Erin
- Najdovski Tome
- Nichol Alistair D.
- Nielsen Henrik
- Novak Richard M.
- O?Sullivan Matthew V. N.
- Olalla Julian
- Osibogun Akin
- Osikomaiya Bodunrin
- Oyonarte Salvador
- P?rez-Alba Eduardo
- Pardo-Oviedo Juan M.
- Patel Mahesh C.
- Paterson David L.
- Pe?a-Perez Carlos A.
- Perez-Calatayud Angel A.
- Perkina Anastasia
- Perry Naomi
- Pouladzadeh Mandana
- Poyato Inmaculada
- Price David J.
- Quero Anne Kristine H.
- Rahman Md. M.
- Rahman Md. S.
- Ram?rez-Santana Carolina
- Ramesh Mayur
- Rasmussen Magnus
- Rees Megan A.
- Rego Eduardo
- Roberts David J.
- Roberts Jason A.
- Rodr?guez Yhojan
- Rodr?guez-Ba?o Jes?s
- Rogers Benjamin A.
- Rojas Manuel
- Romero Alberto
- Rowan Kathryn M.
- Saccona Fabio
- Safdarian Mehdi
- Santos Maria Clariza M.
- Sasadeusz Joe
- Schmitt Andreas M.
- Scozzari Gitana
- Shankar-Hari Manu
- Sharma Gorav
- Smith Emily R.
- Snelling Thomas
- Soto Alonso
- Tagayuna Pedrito Y.
- Tang Amy
- Tatem Geneva
- Teofili Luciana
- The Faculty of Medicine
- Tong Steven Y. C.
- Turgeon Alexis F.
- van?t Hooft Janneke
- Veloso Januario D.
- Venkatesh Balasubramanian
- Ventura-Enriquez Yanet
- Webb Steve A.
- Wiese Lothar
- Wik?n Christian
- Wood Erica M.
- Yusubalieva Gaukhar M.
- Zacharowski Kai
- Zarychanski Ryan
- Publication venue
- BMC Infect Dis
- Publication date
- 01/01/2021
- Field of study
Funder: laura and john arnold foundationBACKGROUND: Convalescent plasma has been widely used to treat COVID-19 and is under investigation in numerous randomized clinical trials, but results are publicly available only for a small number of trials. The objective of this study was to assess the benefits of convalescent plasma treatment compared to placebo or no treatment and all-cause mortality in patients with COVID-19, using data from all available randomized clinical trials, including unpublished and ongoing trials (Open Science Framework, https://doi.org/10.17605/OSF.IO/GEHFX ). METHODS: In this collaborative systematic review and meta-analysis, clinical trial registries (ClinicalTrials.gov, WHO International Clinical Trials Registry Platform), the Cochrane COVID-19 register, the LOVE database, and PubMed were searched until April 8, 2021. Investigators of trials registered by March 1, 2021, without published results were contacted via email. Eligible were ongoing, discontinued and completed randomized clinical trials that compared convalescent plasma with placebo or no treatment in COVID-19 patients, regardless of setting or treatment schedule. Aggregated mortality data were extracted from publications or provided by investigators of unpublished trials and combined using the Hartung-Knapp-Sidik-Jonkman random effects model. We investigated the contribution of unpublished trials to the overall evidence. RESULTS: A total of 16,477 patients were included in 33 trials (20 unpublished with 3190 patients, 13 published with 13,287 patients). 32 trials enrolled only hospitalized patients (including 3 with only intensive care unit patients). Risk of bias was low for 29/33 trials. Of 8495 patients who received convalescent plasma, 1997 died (23%), and of 7982 control patients, 1952 died (24%). The combined risk ratio for all-cause mortality was 0.97 (95% confidence interval: 0.92; 1.02) with between-study heterogeneity not beyond chance (I2 = 0%). The RECOVERY trial had 69.8% and the unpublished evidence 25.3% of the weight in the meta-analysis. CONCLUSIONS: Convalescent plasma treatment of patients with COVID-19 did not reduce all-cause mortality. These results provide strong evidence that convalescent plasma treatment for patients with COVID-19 should not be used outside of randomized trials. Evidence synthesis from collaborations among trial investigators can inform both evidence generation and evidence application in patient care
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
- Author
- Aanniz Tarek
- Abar Aden Elmi
- Abbad Anass
- Abdelfattah May
- Abdelhamid W.
- Abdella Saro
- Abdellah Faouzi
- Abdelmjid El Oualid
- Abdelmoula Fatma
- Abdelmoulah F.
- Abderrahmane Maaroufi
- Abderrazak Rfaki
- Abdillahi Idil Salah
- Abdissa Alemseged
- Abdo I.
- Abdoelraheem Mohamed Hassan
- Abe Haruka
- Abebe Markos
- Abechi Priscilla
- Abera Adugna
- Abi Rachid
- Abias Abe G.
- Abichu Getachew
- Abid N.
- Abid Nabil
- Abid Salma
- Abilio Nuro
- Abimbola Sharon
- Abo Shama Noura M
- Abosede O.
- Aboubaker Mohamed Houmed
- Abouelhoda Mohamed
- Abouelnaga S.
- Abualas Elamin
- Abubeker Ramalia Chabi
- Abuelenein Ehab Abdelkader
- Abuzaid Nadir
- Abworo Edward O.
- Ada Diosdado Odjama Nseng
- Addidle Michael
- Adegbola Richard
- Adegnika Akim A.
- Adegnika Ayola Akim
- Adel Abd Monaem
- Adeniji Johnson A.
- Adepetun Tomiwa
- Adesegun A.
- Adesuyi Omoare
- Adetifa Ifedayo M. O.
- Adewumi Olubusuyi M.
- Adewumi Oluwatimilehin
- Adewumi Praise
- Adeyemi Kayode T.
- Adhikari Bishwo N.
- Adil El Hamouchi
- Adjiratou Aissatou B. A.
- Adnew Bethlehem
- Adu Bright
- Adu Eric
- Adusei-Poku Mildred
- Agbenyo Seyram Bless
- Agbodzi B.
- Ageez A.M.
- Agoti Charles N.
- Aguenaou Hassan
- Agwa Sara Hassan
- Agweyu Ambrose
- Ahmed El Bara
- Ahmed Elhadi A.
- Ahmed Hatem
- Ahmed M.
- Ahmed O. S.
- Ahmed Rahma
- Ahmed Shymaa S.
- Ahmed Side Mohamed
- Ahmed Yahaya Ali
- Ahouidi Ambroise
- Ahuka-Mundeke Steve
- Ahumibe Anthony
- Ahyong Vida
- Aissam El Aliani
- Ajayi Nnennaya A.
- Ajibaye Solomon
- Ajili F.
- Ajogbasile F.V.
- Ajogbasile Fehintola V.
- Akanbi Olusola Anuoluwapo
- Akenji Blaise MBoringong
- Akhoud Youssef
- Akinola Monilade
- Akogbeto Petas
- Akoua-Koffi Chantal G.
- Akpede George O.
- Al Onifade Fattah
- Alain Etoundi Mballa
- Alaoui Afaf
- Alaoui-Amine Sanaa
- Alarif Ahlam
- Alaruusi A. M.
- Albert Mélanie
- AlEmam Adba Alfatih
- Alemayehu Dawit Hailu
- Alemu Fekadu
- Algheriani Raiva
- Ali Abraham
- Ali M.A.
- Ali Mohamed Ahmed
- Ali Mushal
- Ali Wael
- Alkarim Mona O.A.
- Allam Loubna
- Allam Mushal
- Allam Mushal
- Altamura Settimia
- Amar Narjis
- Amenga-Etego Lucas N.
- Amer K. E.
- Amer Khaled
- Amira Souissi
- Amoako Daniel G.
- Amoo Olufemi Samuel
- Amoth Patrick
- Amougou Marie
- Ampofo William K.
- Amuri Adrienne A.
- Amuzu Dominic S. Y.
- Amzazi Saaïd
- Anang Abraham Kwabena
- Anas Abbad
- Andeko Julia C.
- Andersen Kristian
- Andersson Hana Sofia
- Andika Brian
- Andres Moreira-Soto
- Andriam Soa Fy
- Andriamandimby Soa Fy
- Anga Latifa
- Ange Dossou
- Angelov Angel
- Anna-Lena Sander
- Annajr B.
- Anoh Etilé A.
- Anscombe Catherine
- Antwerpen Markus H.
- Anu Campbell
- Anyaneji Ugochukwu J.
- Anyika Chinyere
- Aouni M.
- Appiah Vincent
- Appiah-Kubi Joyce
- Arena Fabio
- Arjaquah Augustina
- Arjarquah A.
- Armand Edang-Minko
- Armanious Riad Mounir
- Armoo Samuel
- Arnaldo Paulo
- Arnold Catherine E.
- Arrouchi Housna
- Artesi Maria
- Aryeetey Sherihane
- Asamoah Jesse Addo
- Asante Ivy A.
- Asare K.M.
- Ashton Philip
- Ashton Phillip
- Asiedu Ernest
- Asiedu-Bekoe Franklyn Egbe
- Asiimwe Stephen
- Askander Omar
- Asmamaw Kominist
- Assane Hamadi
- Assoumou Samira Zoa
- Atiga N.
- Attiku Keren Okyerebea
- Audu Rosemary A.
- Auld A.
- Awandare Gordon A.
- Awinda George
- Awunyo Sena
- Ayansola Oyeronke
- Ayei James
- Ayekaba Mitoha Ondo’o
- Ayivor-Djanie Reuben
- Aymane Bouzidi
- Ayo-Ale B.
- Ayoade F.
- Ayoola Joy
- Ayouba Ahidjo
- Aziz Ramy Karam
- Aziza Amuri
- Azman Andrew
- Aïssi Melchior A. Joël
- Ba-Diallo Awa
- Babatunde Sunday
- Baboo S. B.
- Badjo Ange
- Badou Yvette
- Bagaya Bernard Ssentalo
- Bah Mamadou Saliou
- Bahadoor B. S.
- Bahnassy A.A.
- Bajjou Tahar
- Baker David
- Baker Noah
- Bakhash Shah Mohamed
- Bakry U.
- Balde Aladje
- Balde Aladje
- Balm Michelle
- Bamourou Diané
- Banda R.
- Bane S.
- Barasa Edwine
- Barbet Marion
- Bareng Ontlametse T.
- Barilar Ivan
- Barkat Amina
- Barnes Kayla
- Barreh Guedi Ali
- Bashein Abdulla
- Bassène Hubert
- Batchi-Bouyou Armel L.
- Batchi-Bouyou Armel L.
- Bates Matthew
- Batra Dhwani
- Batra R.
- Bauer Peter
- Baxter Cheryl
- Bayih Abebe Genetu
- Bbosa Nicholas
- Bedford Trevor
- Bediako Yaw
- Bedié
- Bedri Shahinaz.A.
- Behillil Sylvie
- Bejon Philip
- Belarbi Essia
- Belfquih Bouchra
- Belkhir A.B.
- Bellefquih Abdelkrim Meziane
- Beloufa Mohamed Amine
- Belournou Grace Angong
- Ben Alaya Nissaf
- Ben Ayed I.
- Ben Boubaker Ilhem Boutiba
- Ben Boubaker Ilhem Boutiba
- Ben Kahla Alia
- Ben Khelil Jalila
- Ben Moussa Mohamed
- Ben Othman Roua
- Ben Romdhane Habiba
- Ben Sassi Manel
- Ben Sassi Mouna
- Benaissa Elmostafa
- Benhida Rachid
- Benkeroum Samira
- Benkirane Hasnae
- Bennett Andrew J.
- Benrahma Houda
- Bensaid M.
- Bensalem Aicha
- Benyahia Amel
- Bestehorn-Willmann Malena S.
- Bester Phillip A.
- Beyene Getachew Tesfaye
- Bhiman Jinal N.
- Bighignoli B.
- Bikangui Rodrigue
- Bimouhen Abderrahmane
- Bingono Sam O'neilla Oye
- Biscornet Leon
- Bishop-Lilly Kimberly A.
- Bitew Molalegne
- Bitrou S.M.
- Bizard Méline
- Bióté Simão Tchuda
- Blackmore Timothy
- Blakiston Matt
- Bloomfield Max
- Bnouyahia Ikram
- Boatemaa Linda
- Bolajoko Bankole
- Bonney Evelyn Y.
- Bonney Joseph H. K.
- Bonney Kofi
- Bontems Sébastien
- Bootsma Sacha
- Borrmann Steffen
- Boter Marjan
- Boujemla Bouchra
- Bours Vincent
- Boussoukou Ismael Pierrick Mikelet
- Bouzid Amal
- Bouzid Jawad
- Bracchitta Fiorenza
- Brechar Ludivine
- Bridges Daniel J.
- Briese Thomas
- Brisebarre Angela
- Brook Cara
- Bssaibis Fatna
- Budiaki Sylvie L.
- BUHARI Mikhail Olayinka
- Bulimo Wallace D
- Bunga Sudhir
- Butel Christelle
- Butera Yvan
- Bwogi Josephine
- Camara Alimou
- Camara Makhtar
- Campbell Allan
- Campbell Julian
- Cancino Irving
- Candé Adul
- Capel Camille
- Carey Omondi Francis
- Carniel Elisabeth
- Carr Rosina A. A.
- Carri Valeria Delli
- Carvalho Kevin S.
- Cassama Faatu
- Cedola Donatella
- Cer Regina Z.
- Chabert-Consen Marie Madeleine
- Chabuka L. B.
- Chabuka Lucious
- Chambaro H.
- Chammam Sara
- Chamman Sarra
- Chanda D.
- Changula K.
- Charlene Sonal P.
- Chawech H.
- Chenaoui Mohamed
- Chenwi Collins
- Chestakova Irina
- Chgouri Fatima
- Chilufya C.
- Chilufya Moses
- Chimedza Jasper
- Chinedu Ugwu
- Chipimo P.J.
- Chitanga S.
- Chitechi Esther
- Chitenje M.
- Chiwaula M. J.
- Choga Wonderful T.
- Chouati Taha
- Chouikha Anissa
- Christoffels Alan
- Chtourou A.
- Chukwu Chimaobi
- Chukwu G.
- Cigolo Jean-Claude Makangara
- Cisse Barada
- Clarisse Murebwayire
- Colson Philippe
- Comas Iñaki
- Combe Patrice
- Corman Victor Max
- Cortes Carlos
- Cotten Matthew
- Crawford M.
- Crespin Xavier
- Cá Milanca Agostinho
- D'Amore N.
- D'Aprile Annamaria
- Dadi Hailu
- Daghfous Riadh
- Dagnran Anoumou
- Dakka Hanae
- Dal Monego Simeone
- Damaris Matoke-Muhia
- Damena D.
- Damilari Dabiri
- Daniels Rodney S.
- Dao Sounkalo
- Daou Amadou
- Dara Antoine
- Daubenberger Claudia
- David Kumbelembe
- Davids Micheala
- Davies Mary-Ann
- Dawood R.M.
- Dawood Reham
- de Laurent Zaydah R.
- de Ligt Joep
- De Nittis Rosella
- de Oliveira Filho Edmilson F.
- de Oliveira Martins Leonardo
- de Oliveira Tulio
- De Sanctis R.
- de Silva Thushan I
- DeAlmeida Mary
- Debela Alemu Tike
- Delaney Kayla
- Delaporte Eric
- Delerce Jeremy
- Dellagi Koussay
- Deng Guohong
- Deng Lul Lojok
- DeRisi Joseph L.
- Derrar Fawzi
- Descheemaeker Patrick
- Deschenes Michael V.
- Desta Adey Feleke
- Detweiler Angela M.
- Devatchagni Syntyche
- Devaux Christian A.
- Dhaala Beatrice
- Dia Aminata
- Dia Ndongo
- Dia Yacine Amet
- Diab A.
- Diagne Diabou
- Diagne Moussa M.
- Diakite Mandiou
- Diallo Amadou
- Diallo Haby
- Diallo Penda Malhado
- Diallo Sada
- Diarra B.
- Diarra Bassirou
- Diaw Papa Alassane
- Diawara Idrissa
- Dieng Alle Baba
- Dieng Assane
- Diergaardt Azaria
- Diop Mamadou
- Diop Oumy
- Djimde Abdoulaye
- Djingarey Mamoudou Harouna
- Djomsi Dowbiss Meta
- Djontu Jean Claude
- Dobi Paul
- Donati Flora
- Dorkenoo Ameyo
- Doudou Fetouma
- Douffan Messanh
- Doumbia Seydou
- Draper C.
- Dratibi Fred A.
- Drinkovic Dragana
- Drosten Christian
- Duedu Kwabena O.
- Durkin Keith
- Dussart Philippe
- Dussart Philippe
- Dürr Kouriba
- Ebied Fatma
- Ebong Ofonime
- Eckstein Simone
- Edu Emame
- Eggan Stephen M.
- Egli Adrian
- Egoh Ifunanya
- Egyir B.
- Ehlan Amivi
- El Amin Ghizlane
- El ansari Fatima Zahra
- El Atar Jalil
- El Fahime Elmostafa
- El Falaki Fatima
- El Guindy Nancy M.
- El Hady Yassine
- El Jaoudi Rachid
- El Jebari Hanen
- El Mazouri Safae
- El Mrimar Nadia
- El Sayes Mohamed
- El-Duah Philip
- El-Shaqnqery H.
- El-Shesheny Rabeh
- El-Taweel Ahmed
- El-Zayat M.
- Elahmer Omar
- Elalaoui Mly Abdelaziz
- Elannaz Hicham
- Elarab Hoda Ezz
- Elargoubi A.
- Elfihri Mohammed Walid Chemao
- Elgahzaly Hesham
- Elgohary Mohamed Abdel-Salam
- Elguindy Nancy
- Elhadidi Mohamed
- Elhag Khabab A.
- Elhamoumi Siham
- ElHefnawi Mahmoud
- Elhoseiny Mostfa
- Elhoseny M.M.
- Elhosieny F.W.
- Elisabeth Carniel
- Elkhateeb S.M.
- Elkochri Safae
- Ella Kevine Zang
- Ellis Sean
- ElMoussi Awatef
- Elnakib Mostfa
- Eloualid Mjid
- Elouanass M.
- Elouennass Mostafa
- Elroby Ola
- Elsaid Manal Hamdy
- Elsawy Laila
- Elsayed Ahmed
- Elshora Hagar
- Elsissy M.H.
- Elvy Juliet
- Elzagheid Adam I.
- Embaló Bubacar Delgado Pinto
- Emna Gaies
- Emokpae Uyi
- Enatha Mukantwari
- Endjala Nathalia
- Engelbrecht Susan
- Ennibi H.
- Enouf Vincent
- Erameh Cyril
- Erhart Annette
- Eshun Miriam
- Essabbar Abdelomunim
- Essabbar Mouneem
- Essayagh Touria
- Essomba René G.
- Essone Paulin N.
- Estrella Luis A.
- Everatt Josie
- Exler Jan Felix
- Ezzelarab M.H.
- Fadeyi Abayomi
- Fageer Sameira M.
- Fageer Samira M.
- Faggioni G.
- Fahsbender E.
- Fainguem Ndine
- Faisal Muhammad
- Fakayode Oluwatosin
- Fakhfakh Ahmed
- Fall Mbengué
- Faouzi Abdellah
- Faouzia Zemmouri
- Farawyla H.
- Fares Wasfi
- Farghaly Ayman
- Faye Martin
- Faye Ousmane
- Feasey Nicholas
- Fedorov A.V.
- Fekkak Jamal
- Femi Ayoade
- Femi Oladiji
- Femi Saibu
- Fenollar Florence
- Ferjani Asma
- Ferjani Sana
- Fidelia Hinson
- Fikry A.E.
- Fillo S.
- Fki-berrajah L.
- Fki-Berrajah Lamia
- Foda Iman
- Fokam Joseph
- Folarino O.
- Folorunsho Francine
- Foster-Nyarko Ebenezer
- Foudi Martin Maidadi
- Foulkes Benjamin H.
- Fournier Pierre-Edouard
- Fowora Muinah Adenike
- Fowotade Adeola
- Francisco Ngiambudulu M.
- Frans Ndahafa
- Fred Tei-Maya
- Freed Nikki
- Freeman Josh
- Freitas R. H.
- Frempong Hilda Opoku
- Fuh-Neba T.
- Fwoloshi Somda Soro Georgina
- Gaaloul I.
- Gad Ahmed F.
- Gadzama Galadima
- Gaies Emna
- Galal
- Galiwango Ronald M.
- Galvao Bruna
- Garcia Guillermo
- Gardoul Mouhcine
- Gargouri S.
- Gargouri Saba
- Garry R.
- Garus-Oas Nathalia
- Gaseitsiwe Simani
- Gatare Swaibu
- Gaye-Gaye Astou
- Gdoura Mariem
- Gedeon Jude
- Gelanew Tesfaye
- George Uwem E.
- Gerard Izuwayo
- GeurtsvanKessel Corine H.
- Gevao Sahr
- Gharmaz Hamza
- Ghassan Adib
- Ghedira Kais
- Ghita Amalou
- Ghoulame Safae
- Giandhari Jennifer
- Gideon Nsubuga
- Giordani F.
- Girgis Samia Abdou
- Gismondo Maria Rita
- Githii Rachid
- Githinji George
- Gnimadi Thibaut Armel Cherif
- Goba Augustine
- Godwe Celestin
- Goedhals Dominique
- Goldstone R.
- Gomaa C.
- Gomaa Mokhtar
- Goodfellow Ian
- Goredema Alexander
- Gorman Richmond
- Gorova Vivianne
- Gosnell B. I.
- Gottberg A.
- Gouider Riadh
- Grace Chukwa
- Grad Alia
- Grant Donald S.
- Grantz Kyra
- Grayo Solène
- Greninger Alexander
- Guedouar Houssem
- Gueye Abdou Salam
- Gueye Khadim
- Gueye Ousseynou
- Guindo Ibrahima
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- Jefferies Sarah
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- Singh Lavanya
- Sinyange N.
- Sisay Abay
- Sitharam Nikita
- Sitoe Nadia
- Sivro Aida
- Skarwan Emilio
- Skidmore Peter T.
- Smeti Ibtihel
- Smit Erasmus
- Smith-Lawrence Pamela
- Smyej Imane
- Soara Nabila
- Sobajo Tope
- Soglo Philip M.
- Sogodogo Heitzer
- Sogodogo Sokhna
- Sokei Judith
- Sokhna Cheikh
- Soliman Hany K.
- Soliman May Sherif
- Soliman Shaimaa
- Somboro Anou M.
- Somé Arsène
- Sonoo Janaki
- Sorie Foday Sahr Samuel
- Sorie Samuel
- Sosedova E.A.
- Souiri Amal
- Souissi Amal
- Souma Zein
- Soumah Abdoul Karim
- Souopgui Jacob
- Sourakatou Salifou
- Sow Abdourahmane
- Sow Mamadou Saliou
- Ssemwanga Deogratius
- Ssewanyana Isaac
- Ssuuna Charles
- Stambouli Nejla
- Stander Tania
- Stange Madlen
- Stanley Sarah
- Stefanov Emily K.
- Stoecker Kilian
- Storey Matt
- Strydom Amy
- Subramoney Kathleen
- Sujeewon C.
- SULAIMAN Mariam Kehinde
- Sule Waidi
- Sun Fengming
- Swanson Kena
- Sylvanus Okogbenin
- Sylverken Augustina A.
- Symeker S.L.
- Symekher Samwel Lifumo
- Tagajdid Rida
- Taha A.G.
- Taha Ahmed
- Taha Chouati
- Taiwo Babafemi O.
- Takada A.
- Takawira Faustinos T.
- Takawira Tatenda
- Takou Desire
- Taloa K.A.
- Tamfum Jean-Jacques M.
- Tan M.
- Tan Michelle
- Tarnagda Zekiba
- Tarupiwa Andrew
- Tatfeng Mirabeau Y.
- Tato C.
- Tato Cristina M.
- Taweh Fahn M.
- Tayachew Adamu
- Tayimetha Carolle Yanique
- Taylor Susan
- Tchibozo Carine
- Tchoudjin Herve Christian Paho
- Tebeje Yenew K.
- Tefelo Thela
- Tefera D.A.
- Tefera Dessalegn Abeje
- Tegally Houriiyah
- Tegomoh Bryan
- Tegueni Kokou
- Tei-Maya
- Teka Gizaw
- Tembo John
- Tesfaye Abraham
- Tesfaye Gelanew
- Tesfaye Kassahun
- Tessema Sofonias K.
- Testimony Olumade
- Thiam Aminata Sileymane
- Thilliez Gaetan
- Thiongo K.
- Thomas Van L.
- Tia Alie
- Tinto Halidou
- Tollera Getachew
- Tombolomako T. B.
- Tomkins-Tinch C.
- Tomori Oyewale
- Tongo Marcel
- Top Ndeye Marieme
- Tordo Noël
- Toure Abdoulaye
- Touré Bamba Fatoumata
- Touzani Charifa Drissi
- Touzani Otmane
- Trabelsi Sameh
- Traoré
- Traoré Adjaratou
- Treurnicht Florette
- Triki H.
- Triki Henda
- Trotter Alexander J.
- Tsegay Yao
- Tshiabuila Derek
- Tsiry R.
- Tsofa Benjamin
- Tuki Keyru
- Tumedi Kefentse A.
- Turki M.
- Tushabe Phionah
- Tuyisenge Patrick
- Tyers Lynn
- Uche Peace O.
- Ugwu C.A.
- Ulrich M.
- Umumararungu Esperance
- Umuringa Jeanne d’Arc
- Upton Arlo
- Ushijima Yuri
- Ussher James
- Utpatel Christian
- Uwanibe Jessica N.
- Uwituze Arlene
- van der Eijk Annemiek
- van der Linden Anne
- van der Linden Antje
- van der Werf Sylvie
- Van Rooyen G.
- van Rooyen Gerhard
- van Wyk Stephanie
- van Zyl Gert U.
- Vanaerschot M.
- Vanmechelen Bert
- Vanpeene Maud
- Velavan Thirumalaisamy P.
- Venter Marietjie
- Vernet Marie-Astrid
- Viana R.
- Vickos U.
- Victoir Kathleen
- Vida Ahyong
- Vidal Nicole
- Viegas Sofia
- Vincent Grace
- Vinze Anika
- Voegtly Logan J.
- von Gottberg Anne
- Waberi Zeinab Ali
- Wadi Amira Suliaman
- Wadonda N.
- Wadula J.
- Wagner Philipp
- Wahab Kolawole Wasiu
- Waitumbi John
- Walter Mathias C.
- Wamala Joseph F.
- Wandera Dennis N.
- Wang Jing
- Wang Xiuhua
- Wani Gregory
- Wanjohi Dorcas W.
- Wanok Stephen
- Waruhiu C.N.
- Waruhiu Cecilia
- Wasfi Fares
- Watters Chaselynn M.
- Wawina-Bokalanga Tony
- Wayengera Misaki
- Wayoro Oby
- Webby R.
- Webby Richard
- Weldemariam A.G.
- Weldemariam Atsbeha G.
- Werno Anja
- Wiley Michael R.
- Wilkinson David
- Wilkinson Eduan
- Williamson Carolyn
- Wilson Shannon
- Woelfel R.
- Wohl Shirlee
- Wolh S.
- Wolter Nicole
- Wuduri Zara
- Wulf Ben
- Wurie I.
- Wurie Isatta
- Xavier Joicymara S.
- Xiang Zuzheng
- Xie Hong
- Yadouleton Anges
- Yadouleton Yahya
- Yakout Mostfa
- Yandoko Rivalyn Nakoune
- Yang Qi
- Yao Kouadio T.
- Yassine Kasmi
- Yassine Zouheir
- Yasuda Jiro
- Yatassaye Bouna
- Yeboah C.
- Yeboah Richmond
- Yeboah-Manu Dorothy
- Yemi Bright K.
- Yiaba Cyrus
- Yiaba Warren Cyrus
- Yu Popova A.
- Yusuf Nyam Itse
- Yusuf Yacob Mohamed
- Zablon J. Matoke D.
- Zablon J.O.
- Zaher Tarek Refaat Elnagdy Raafat
- Zahra El Ansari Fatima
- Zahran Manal Hamdy
- Zekri Abdel-Rahman N.
- Zhang J.
- Zhou Pei
- Zinyowera Sekesai
- Zong Minko O.
- Zongo Arsène
- Zorgani A.
- Zouaki Amal
- Zulu P.
- Zumla Ali
- Zumla Alimuddin
- Zuze Boitumelo
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 07/10/2022
- Field of study
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
Cross-reaction between Formosan termite (Coptotermes formosanus) proteins and cockroach allergens
- Author
- A Pomes
- A Renand
- AI Ntukuyoh
- AL Lopata
- AL Szalanski
- B Bloom
- BA Rumpold
- C Srinroch
- Carrie B. Cottone
- Casey C. Grimm
- Christopher B. Florane
- Christopher P. Mattison
- Claudia Riegel
- CP Mattison
- CP Mattison
- D Inward
- D Pimental
- D Raubenheimer
- D Zhang
- D Zhang
- E Dobrovolskaia
- FA Rabito
- FA Rabito
- GA Mueller
- HC Santiago
- HSG Tan
- J Fernandes
- JA Jenkins
- Jay E. Slater
- JC Gore
- JE Gern
- JE Slater
- JM Rothman
- KC Verhoeckx
- LK Arruda
- LK Arruda
- LK Arruda
- LN Zheng
- Matthew R. Tarver
- MD Chapman
- MG Paoletti
- MJ Sereda
- MJ Sereda
- ML Patterson
- MR Tarver
- NY Su
- NY Su
- NY Su
- O Olmedo
- R Ayuso
- R Ayuso
- RC O'Malley
- S van Broekhoven
- Suman B. Pakala
- Sunil K. Ahuja
- T Khurana
- T Khurana
- T Khurana
- T Khurana
- Taruna Khurana
- W Cookson
- WC McGrew
- WW Busse
- Yvette Bren-Mattison
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Additional file 2 of Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials
- Author
- Aalborg University Hospital
- Abayomi Akin
- Abduljalil Manal
- Abdulrahman Abdulkarim
- Acosta-Ampudia Yeny
- Aguilar-Guisado Manuela
- Al-Beidh Farah
- Alejandria Marissa M.
- Alfonso Rachelle N.
- Ali Mohammad
- AlQahtani Manaf
- AlZamrooni Alaa
- Anaya Juan-Manuel
- Ang Mark Angelo C.
- Aomar Ismael F.
- Argumanis Luis E.
- Averyanov Alexander
- Axfors Cathrine
- Baklaushev Vladimir P.
- Balionis Olga
- Benfield Thomas
- Berry Scott
- Birocco Nadia
- Bonifacio Lynn B.
- Bowen Asha C.
- Bown Abbie
- Cabello-Gutierrez Carlos
- Camacho Bernardo
- Camacho-Ortiz Adrian
- Campbell-Lee Sally
- Cao Damon H.
- Cardesa Ana
- Carnate Jose M.
- Castillo German Jr. J.
- Cavallo Rossana
- Chowdhury Fazle R.
- Chowdhury Forhad U. H.
- Ciccone Giovannino
- Cingolani Antonella
- Climacosa Fresthel Monica M.
- Compernolle Veerle
- Cortez Carlo Francisco N.
- Costa Neto Abel
- D?Antico Sergio
- D?az Ponce-Medrano Juan A.
- D?az-Coronado Juan C.
- Daly James
- Danielle Franca
- Davis Joshua S.
- De Rosa Francesco Giuseppe
- Denholm Justin T.
- Denkinger Claudia M.
- Department of Clinical Medicine
- Department of Infectious Diseases
- Desmecht Daniel
- Donneau Anne-Fran?oise
- Dumagay Teresita E.
- Dunachie Susanna
- Dungog Cecile C.
- Erinoso Olufemi
- Escasa Ivy Mae S.
- Estcourt Lise J.
- Evans Amy
- Evasan Agnes L. M.
- Fareli Christian J.
- Fernandez-Sanchez Veronica
- G?mez-Almaguer David
- Galassi Claudia
- Gallo Juan E.
- Garcia Jesus A.
- Garcia Patricia J.
- Garcia Patricia L.
- Garigliany Mutien
- Garza-Gonzalez Elvira
- Gauiran Deonne Thaddeus V.
- Gaviria Garc?a Paula A.
- Giron-Gonzalez Jose-Antonio
- Goodman Steven N.
- Gordon Anthony C.
- Gothot Andr?
- Grass Guaqueta Jeser Santiago
- Green Cameron
- Grimaldi David
- Haber Noah A.
- Hammond Naomi E.
- Harvala Heli
- Hemkens Lars G.
- Heralde Francisco M.
- Herrick Jesica
- Higgins Alisa M.
- Hills Thomas E.
- Hines Jennifer
- Holm Karin
- Hoque Ashraful
- Hospital Universitario de Jerez de la Frontera
- Hoste Eric
- Ignacio Jose M.
- Ioannidis John P. A.
- Ivanov Alexander V.
- Janiaud Perrine
- Janssen Maike
- Jennings Jeffrey H.
- Jha Vivekanand
- Khanna Nina
- King Ruby Anne N.
- Kjeldsen-Kragh Jens
- Klenerman Paul
- Klinik Medicin og Akut
- Kotecha Aditya
- Krapp Fiorella
- L?pez-C?rdenas Salvador
- L?pez-Robles Concepci?n
- Labanca Luciana
- Laing Emma
- Landin-Olsson Mona
- Laterre Pierre-Fran?ois
- Lim Jodor
- Lim Lyn-Li
- Ljungquist Oskar
- Llaca-D?az Jorge M.
- Lopez-Plaza Ileana
- Lucero Josephine Anne C.
- Lundgren Maria
- M?ller-Tidow Carsten
- Mac?as Juan
- Maganito Sandy C.
- Malundo Anna Flor G.
- Manrique Rub?n D.
- Manzini Paola M.
- Marcos Miguel
- Marquez Ignacio
- Mart?nez-Marcos Francisco Javier
- Mata Ana M.
- McArthur Colin J.
- McQuilten Zoe K.
- McVerry Bryan J.
- Menon David K.
- Meyfroidt Geert
- Mirasol Ma. Angelina L.
- Misset Beno?t
- Moher David
- Molton James S.
- Mondragon Alric V.
- Monsalve Diana M.
- Moradi Choghakabodi Parastoo
- Morpeth Susan C.
- Mouncey Paul R.
- Moutschen Michel
- Murphy Erin
- Najdovski Tome
- Nichol Alistair D.
- Nielsen Henrik
- Novak Richard M.
- O?Sullivan Matthew V. N.
- Olalla Julian
- Osibogun Akin
- Osikomaiya Bodunrin
- Oyonarte Salvador
- P?rez-Alba Eduardo
- Pardo-Oviedo Juan M.
- Patel Mahesh C.
- Paterson David L.
- Pe?a-Perez Carlos A.
- Perez-Calatayud Angel A.
- Perkina Anastasia
- Perry Naomi
- Pouladzadeh Mandana
- Poyato Inmaculada
- Price David J.
- Quero Anne Kristine H.
- Rahman Md. M.
- Rahman Md. S.
- Ram?rez-Santana Carolina
- Ramesh Mayur
- Rasmussen Magnus
- Rees Megan A.
- Rego Eduardo
- Roberts David J.
- Roberts Jason A.
- Rodr?guez Yhojan
- Rodr?guez-Ba?o Jes?s
- Rogers Benjamin A.
- Rojas Manuel
- Romero Alberto
- Rowan Kathryn M.
- Saccona Fabio
- Safdarian Mehdi
- Santos Maria Clariza M.
- Sasadeusz Joe
- Schmitt Andreas M.
- Scozzari Gitana
- Shankar-Hari Manu
- Sharma Gorav
- Smith Emily R.
- Snelling Thomas
- Soto Alonso
- Tagayuna Pedrito Y.
- Tang Amy
- Tatem Geneva
- Teofili Luciana
- The Faculty of Medicine
- Tong Steven Y. C.
- Turgeon Alexis F.
- van?t Hooft Janneke
- Veloso Januario D.
- Venkatesh Balasubramanian
- Ventura-Enriquez Yanet
- Webb Steve A.
- Wiese Lothar
- Wik?n Christian
- Wood Erica M.
- Yusubalieva Gaukhar M.
- Zacharowski Kai
- Zarychanski Ryan
- Publication venue
- Figshare
- Publication date
- 01/01/2021
- Field of study
Additional file 2. Email invitation
Additional file 7 of Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials
- Author
- Aalborg University Hospital
- Abayomi Akin
- Abduljalil Manal
- Abdulrahman Abdulkarim
- Acosta-Ampudia Yeny
- Aguilar-Guisado Manuela
- Al-Beidh Farah
- Alejandria Marissa M.
- Alfonso Rachelle N.
- Ali Mohammad
- AlQahtani Manaf
- AlZamrooni Alaa
- Anaya Juan-Manuel
- Ang Mark Angelo C.
- Aomar Ismael F.
- Argumanis Luis E.
- Averyanov Alexander
- Axfors Cathrine
- Baklaushev Vladimir P.
- Balionis Olga
- Benfield Thomas
- Berry Scott
- Birocco Nadia
- Bonifacio Lynn B.
- Bowen Asha C.
- Bown Abbie
- Cabello-Gutierrez Carlos
- Camacho Bernardo
- Camacho-Ortiz Adrian
- Campbell-Lee Sally
- Cao Damon H.
- Cardesa Ana
- Carnate Jose M.
- Castillo German Jr. J.
- Cavallo Rossana
- Chowdhury Fazle R.
- Chowdhury Forhad U. H.
- Ciccone Giovannino
- Cingolani Antonella
- Climacosa Fresthel Monica M.
- Compernolle Veerle
- Cortez Carlo Francisco N.
- Costa Neto Abel
- D?Antico Sergio
- D?az Ponce-Medrano Juan A.
- D?az-Coronado Juan C.
- Daly James
- Danielle Franca
- Davis Joshua S.
- De Rosa Francesco Giuseppe
- Denholm Justin T.
- Denkinger Claudia M.
- Department of Clinical Medicine
- Department of Infectious Diseases
- Desmecht Daniel
- Donneau Anne-Fran?oise
- Dumagay Teresita E.
- Dunachie Susanna
- Dungog Cecile C.
- Erinoso Olufemi
- Escasa Ivy Mae S.
- Estcourt Lise J.
- Evans Amy
- Evasan Agnes L. M.
- Fareli Christian J.
- Fernandez-Sanchez Veronica
- G?mez-Almaguer David
- Galassi Claudia
- Gallo Juan E.
- Garcia Jesus A.
- Garcia Patricia J.
- Garcia Patricia L.
- Garigliany Mutien
- Garza-Gonzalez Elvira
- Gauiran Deonne Thaddeus V.
- Gaviria Garc?a Paula A.
- Giron-Gonzalez Jose-Antonio
- Goodman Steven N.
- Gordon Anthony C.
- Gothot Andr?
- Grass Guaqueta Jeser Santiago
- Green Cameron
- Grimaldi David
- Haber Noah A.
- Hammond Naomi E.
- Harvala Heli
- Hemkens Lars G.
- Heralde Francisco M.
- Herrick Jesica
- Higgins Alisa M.
- Hills Thomas E.
- Hines Jennifer
- Holm Karin
- Hoque Ashraful
- Hospital Universitario de Jerez de la Frontera
- Hoste Eric
- Ignacio Jose M.
- Ioannidis John P. A.
- Ivanov Alexander V.
- Janiaud Perrine
- Janssen Maike
- Jennings Jeffrey H.
- Jha Vivekanand
- Khanna Nina
- King Ruby Anne N.
- Kjeldsen-Kragh Jens
- Klenerman Paul
- Klinik Medicin og Akut
- Kotecha Aditya
- Krapp Fiorella
- L?pez-C?rdenas Salvador
- L?pez-Robles Concepci?n
- Labanca Luciana
- Laing Emma
- Landin-Olsson Mona
- Laterre Pierre-Fran?ois
- Lim Jodor
- Lim Lyn-Li
- Ljungquist Oskar
- Llaca-D?az Jorge M.
- Lopez-Plaza Ileana
- Lucero Josephine Anne C.
- Lundgren Maria
- M?ller-Tidow Carsten
- Mac?as Juan
- Maganito Sandy C.
- Malundo Anna Flor G.
- Manrique Rub?n D.
- Manzini Paola M.
- Marcos Miguel
- Marquez Ignacio
- Mart?nez-Marcos Francisco Javier
- Mata Ana M.
- McArthur Colin J.
- McQuilten Zoe K.
- McVerry Bryan J.
- Menon David K.
- Meyfroidt Geert
- Mirasol Ma. Angelina L.
- Misset Beno?t
- Moher David
- Molton James S.
- Mondragon Alric V.
- Monsalve Diana M.
- Moradi Choghakabodi Parastoo
- Morpeth Susan C.
- Mouncey Paul R.
- Moutschen Michel
- Murphy Erin
- Najdovski Tome
- Nichol Alistair D.
- Nielsen Henrik
- Novak Richard M.
- O?Sullivan Matthew V. N.
- Olalla Julian
- Osibogun Akin
- Osikomaiya Bodunrin
- Oyonarte Salvador
- P?rez-Alba Eduardo
- Pardo-Oviedo Juan M.
- Patel Mahesh C.
- Paterson David L.
- Pe?a-Perez Carlos A.
- Perez-Calatayud Angel A.
- Perkina Anastasia
- Perry Naomi
- Pouladzadeh Mandana
- Poyato Inmaculada
- Price David J.
- Quero Anne Kristine H.
- Rahman Md. M.
- Rahman Md. S.
- Ram?rez-Santana Carolina
- Ramesh Mayur
- Rasmussen Magnus
- Rees Megan A.
- Rego Eduardo
- Roberts David J.
- Roberts Jason A.
- Rodr?guez Yhojan
- Rodr?guez-Ba?o Jes?s
- Rogers Benjamin A.
- Rojas Manuel
- Romero Alberto
- Rowan Kathryn M.
- Saccona Fabio
- Safdarian Mehdi
- Santos Maria Clariza M.
- Sasadeusz Joe
- Schmitt Andreas M.
- Scozzari Gitana
- Shankar-Hari Manu
- Sharma Gorav
- Smith Emily R.
- Snelling Thomas
- Soto Alonso
- Tagayuna Pedrito Y.
- Tang Amy
- Tatem Geneva
- Teofili Luciana
- The Faculty of Medicine
- Tong Steven Y. C.
- Turgeon Alexis F.
- van?t Hooft Janneke
- Veloso Januario D.
- Venkatesh Balasubramanian
- Ventura-Enriquez Yanet
- Webb Steve A.
- Wiese Lothar
- Wik?n Christian
- Wood Erica M.
- Yusubalieva Gaukhar M.
- Zacharowski Kai
- Zarychanski Ryan
- Publication venue
- Figshare
- Publication date
- 01/01/2021
- Field of study
Additional file 7. Sensitivity analyses: various meta-analytic approaches
Additional file 1 of Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials
- Author
- Aalborg University Hospital
- Abayomi Akin
- Abduljalil Manal
- Abdulrahman Abdulkarim
- Acosta-Ampudia Yeny
- Aguilar-Guisado Manuela
- Al-Beidh Farah
- Alejandria Marissa M.
- Alfonso Rachelle N.
- Ali Mohammad
- AlQahtani Manaf
- AlZamrooni Alaa
- Anaya Juan-Manuel
- Ang Mark Angelo C.
- Aomar Ismael F.
- Argumanis Luis E.
- Averyanov Alexander
- Axfors Cathrine
- Baklaushev Vladimir P.
- Balionis Olga
- Benfield Thomas
- Berry Scott
- Birocco Nadia
- Bonifacio Lynn B.
- Bowen Asha C.
- Bown Abbie
- Cabello-Gutierrez Carlos
- Camacho Bernardo
- Camacho-Ortiz Adrian
- Campbell-Lee Sally
- Cao Damon H.
- Cardesa Ana
- Carnate Jose M.
- Castillo German Jr. J.
- Cavallo Rossana
- Chowdhury Fazle R.
- Chowdhury Forhad U. H.
- Ciccone Giovannino
- Cingolani Antonella
- Climacosa Fresthel Monica M.
- Compernolle Veerle
- Cortez Carlo Francisco N.
- Costa Neto Abel
- D?Antico Sergio
- D?az Ponce-Medrano Juan A.
- D?az-Coronado Juan C.
- Daly James
- Danielle Franca
- Davis Joshua S.
- De Rosa Francesco Giuseppe
- Denholm Justin T.
- Denkinger Claudia M.
- Department of Clinical Medicine
- Department of Infectious Diseases
- Desmecht Daniel
- Donneau Anne-Fran?oise
- Dumagay Teresita E.
- Dunachie Susanna
- Dungog Cecile C.
- Erinoso Olufemi
- Escasa Ivy Mae S.
- Estcourt Lise J.
- Evans Amy
- Evasan Agnes L. M.
- Fareli Christian J.
- Fernandez-Sanchez Veronica
- G?mez-Almaguer David
- Galassi Claudia
- Gallo Juan E.
- Garcia Jesus A.
- Garcia Patricia J.
- Garcia Patricia L.
- Garigliany Mutien
- Garza-Gonzalez Elvira
- Gauiran Deonne Thaddeus V.
- Gaviria Garc?a Paula A.
- Giron-Gonzalez Jose-Antonio
- Goodman Steven N.
- Gordon Anthony C.
- Gothot Andr?
- Grass Guaqueta Jeser Santiago
- Green Cameron
- Grimaldi David
- Haber Noah A.
- Hammond Naomi E.
- Harvala Heli
- Hemkens Lars G.
- Heralde Francisco M.
- Herrick Jesica
- Higgins Alisa M.
- Hills Thomas E.
- Hines Jennifer
- Holm Karin
- Hoque Ashraful
- Hospital Universitario de Jerez de la Frontera
- Hoste Eric
- Ignacio Jose M.
- Ioannidis John P. A.
- Ivanov Alexander V.
- Janiaud Perrine
- Janssen Maike
- Jennings Jeffrey H.
- Jha Vivekanand
- Khanna Nina
- King Ruby Anne N.
- Kjeldsen-Kragh Jens
- Klenerman Paul
- Klinik Medicin og Akut
- Kotecha Aditya
- Krapp Fiorella
- L?pez-C?rdenas Salvador
- L?pez-Robles Concepci?n
- Labanca Luciana
- Laing Emma
- Landin-Olsson Mona
- Laterre Pierre-Fran?ois
- Lim Jodor
- Lim Lyn-Li
- Ljungquist Oskar
- Llaca-D?az Jorge M.
- Lopez-Plaza Ileana
- Lucero Josephine Anne C.
- Lundgren Maria
- M?ller-Tidow Carsten
- Mac?as Juan
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- Manzini Paola M.
- Marcos Miguel
- Marquez Ignacio
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- Murphy Erin
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- Nichol Alistair D.
- Nielsen Henrik
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- Olalla Julian
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- Oyonarte Salvador
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- Patel Mahesh C.
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- Pe?a-Perez Carlos A.
- Perez-Calatayud Angel A.
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- Pouladzadeh Mandana
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- Quero Anne Kristine H.
- Rahman Md. M.
- Rahman Md. S.
- Ram?rez-Santana Carolina
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- Rees Megan A.
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- Rogers Benjamin A.
- Rojas Manuel
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- Rowan Kathryn M.
- Saccona Fabio
- Safdarian Mehdi
- Santos Maria Clariza M.
- Sasadeusz Joe
- Schmitt Andreas M.
- Scozzari Gitana
- Shankar-Hari Manu
- Sharma Gorav
- Smith Emily R.
- Snelling Thomas
- Soto Alonso
- Tagayuna Pedrito Y.
- Tang Amy
- Tatem Geneva
- Teofili Luciana
- The Faculty of Medicine
- Tong Steven Y. C.
- Turgeon Alexis F.
- van?t Hooft Janneke
- Veloso Januario D.
- Venkatesh Balasubramanian
- Ventura-Enriquez Yanet
- Webb Steve A.
- Wiese Lothar
- Wik?n Christian
- Wood Erica M.
- Yusubalieva Gaukhar M.
- Zacharowski Kai
- Zarychanski Ryan
- Publication venue
- Figshare
- Publication date
- 01/01/2021
- Field of study
Additional file 1. Search strategy
Additional file 5 of Association between convalescent plasma treatment and mortality in COVID-19: a collaborative systematic review and meta-analysis of randomized clinical trials
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- Aalborg University Hospital
- Abayomi Akin
- Abduljalil Manal
- Abdulrahman Abdulkarim
- Acosta-Ampudia Yeny
- Aguilar-Guisado Manuela
- Al-Beidh Farah
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- Castillo German Jr. J.
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- Daly James
- Danielle Franca
- Davis Joshua S.
- De Rosa Francesco Giuseppe
- Denholm Justin T.
- Denkinger Claudia M.
- Department of Clinical Medicine
- Department of Infectious Diseases
- Desmecht Daniel
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- Dumagay Teresita E.
- Dunachie Susanna
- Dungog Cecile C.
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- Gaviria Garc?a Paula A.
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- Heralde Francisco M.
- Herrick Jesica
- Higgins Alisa M.
- Hills Thomas E.
- Hines Jennifer
- Holm Karin
- Hoque Ashraful
- Hospital Universitario de Jerez de la Frontera
- Hoste Eric
- Ignacio Jose M.
- Ioannidis John P. A.
- Ivanov Alexander V.
- Janiaud Perrine
- Janssen Maike
- Jennings Jeffrey H.
- Jha Vivekanand
- Khanna Nina
- King Ruby Anne N.
- Kjeldsen-Kragh Jens
- Klenerman Paul
- Klinik Medicin og Akut
- Kotecha Aditya
- Krapp Fiorella
- L?pez-C?rdenas Salvador
- L?pez-Robles Concepci?n
- Labanca Luciana
- Laing Emma
- Landin-Olsson Mona
- Laterre Pierre-Fran?ois
- Lim Jodor
- Lim Lyn-Li
- Ljungquist Oskar
- Llaca-D?az Jorge M.
- Lopez-Plaza Ileana
- Lucero Josephine Anne C.
- Lundgren Maria
- M?ller-Tidow Carsten
- Mac?as Juan
- Maganito Sandy C.
- Malundo Anna Flor G.
- Manrique Rub?n D.
- Manzini Paola M.
- Marcos Miguel
- Marquez Ignacio
- Mart?nez-Marcos Francisco Javier
- Mata Ana M.
- McArthur Colin J.
- McQuilten Zoe K.
- McVerry Bryan J.
- Menon David K.
- Meyfroidt Geert
- Mirasol Ma. Angelina L.
- Misset Beno?t
- Moher David
- Molton James S.
- Mondragon Alric V.
- Monsalve Diana M.
- Moradi Choghakabodi Parastoo
- Morpeth Susan C.
- Mouncey Paul R.
- Moutschen Michel
- Murphy Erin
- Najdovski Tome
- Nichol Alistair D.
- Nielsen Henrik
- Novak Richard M.
- O?Sullivan Matthew V. N.
- Olalla Julian
- Osibogun Akin
- Osikomaiya Bodunrin
- Oyonarte Salvador
- P?rez-Alba Eduardo
- Pardo-Oviedo Juan M.
- Patel Mahesh C.
- Paterson David L.
- Pe?a-Perez Carlos A.
- Perez-Calatayud Angel A.
- Perkina Anastasia
- Perry Naomi
- Pouladzadeh Mandana
- Poyato Inmaculada
- Price David J.
- Quero Anne Kristine H.
- Rahman Md. M.
- Rahman Md. S.
- Ram?rez-Santana Carolina
- Ramesh Mayur
- Rasmussen Magnus
- Rees Megan A.
- Rego Eduardo
- Roberts David J.
- Roberts Jason A.
- Rodr?guez Yhojan
- Rodr?guez-Ba?o Jes?s
- Rogers Benjamin A.
- Rojas Manuel
- Romero Alberto
- Rowan Kathryn M.
- Saccona Fabio
- Safdarian Mehdi
- Santos Maria Clariza M.
- Sasadeusz Joe
- Schmitt Andreas M.
- Scozzari Gitana
- Shankar-Hari Manu
- Sharma Gorav
- Smith Emily R.
- Snelling Thomas
- Soto Alonso
- Tagayuna Pedrito Y.
- Tang Amy
- Tatem Geneva
- Teofili Luciana
- The Faculty of Medicine
- Tong Steven Y. C.
- Turgeon Alexis F.
- van?t Hooft Janneke
- Veloso Januario D.
- Venkatesh Balasubramanian
- Ventura-Enriquez Yanet
- Webb Steve A.
- Wiese Lothar
- Wik?n Christian
- Wood Erica M.
- Yusubalieva Gaukhar M.
- Zacharowski Kai
- Zarychanski Ryan
- Publication venue
- Figshare
- Publication date
- 01/01/2021
- Field of study
Additional file 5. Risk of bias
Evolution over Time of Ventilatory Management and Outcome of Patients with Neurologic Disease∗
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- Abderrahim Azzouzi
- Abroug F.
- Achille Kouatchet
- Achim Lunkeit
- Adam Mikstacki
- Aguilera García
- Ahmed Sbihi
- Ai-Chin Cheng
- Ainhoa Rosselló
- Alain Mercat
- Alan Javier Zazu
- Alberto Belenguer
- Alberto Deicas
- Alberto Marino
- Alberto Soler
- Alejandro Algora
- Alejandro Arroliga
- Alejandro de la Serna
- Alejandro Gómez
- Alejandro Raimondi
- Alejandro Risso
- Alfonso Moreno
- Alfonso Muñoz
- Alfredo Padrón
- Alfredo Vasquez-Sandoval
- Ali Aydım Altunkan
- Ali Zeggwagh A.
- Aline Camile Yehia
- Alistair Nichol
- Allan Walkey
- Allison Bone
- Aloísio Marques do Nascimento
- Alvaro van Bommel
- Amalia Martínez de la Gandara
- Amber Monson
- Ambrogio Sansone
- Amee Patrawalla
- Amin P.
- Amine Ali Zeggwagh
- Amparo Ferrandiz
- Amy Waters
- Ana Carolina Caballero
- Ana Esther Trujillo
- Ana Villagrá
- Anders Aneman
- Andrea Gimenez
- Andrea Matte
- Andrea Neville Cracchiolo
- Andreas Schwartz
- Andreas Viehöfer
- Andrei Piontek
- Andrew Bersten
- Andrew Davies
- Andrew Davies
- Andrew Davies
- Andrew Steel
- Andrey Yaroshetskiy
- Anette Mortensen
- Anitha Shenoy
- Ankur Devendra Bhavsar
- Annunziata Mattei
- Anthony Saleh
- Antonina Pigna
- Antonino Giarratano
- Antonio Anzueto
- Antonio Braschi
- Antonio Corcione
- Antonio García-Jiménez
- Antonio Maestre
- Antonio Pesenti
- Antonio Raso
- Antonio Reyes
- Antonio Villa Delgado
- Antonio Viñuales
- Anzueto A.
- Arianna Boggero
- Ariel Chena
- Armando Pedulla'
- Arnaud W Thille
- Ashley Ellis
- Ashley Ellis
- Asisclo J Villagómez Ortiz
- Auke Reidinga
- Ayed Samia
- Barbara Tamowicz
- Barrios D.
- Bas M Kors
- Begoña Balerdi
- Benoit Veber
- Bernabé Álvarez
- Bersten A.
- Bert Beishuizen
- Besbes Mohamed
- Bilge Çetin
- Bin Du
- Bin Du
- Bin Yu
- Bing Sun
- Birgitte Viebaek
- Bladimir Alejandro Gil
- Bo Broberg
- Bo Wang
- Boris Villamagua
- Brian Sherman
- Bruno Bonaccorsi Fernandino
- Bruno do Valle Pinheiro
- Bryan Beatty
- C Canevet
- Cakar N.
- Cameron Knott
- Camilo Pizarro
- Carlo Alberto Acosta
- Carlos Alberto Studart Gomes
- Carlos André Correia Casado
- Carlos Andrés Díaz
- Carlos Gallego
- Carlos Marian Crespo
- Carlos Robles-Arias
- Carmelo Dueñas
- Carmen Campos
- Carolina Gímenez-Esparza
- Carolina Lorencio
- Cartan Costello
- Catherine Simmonds
- Cayce Strength
- Cayetano Galetti
- Cecilia Carbayo
- Cecilia Hermosa
- Cecilia Pereyra
- Cesar Enciso
- Cezar Mihailescu
- Chabu Coronado
- Chafrina Marie Olay
- Chang Liu
- Chantal Hogan
- Charki Haimeur
- Chau Chin Man
- Chen Chin-Ming
- Chengmin Yu
- Cheromi Sittambalam
- Cheryl Cuzner
- Cheryl Ethier
- Chiara Verga
- Christian Frenkel
- Christian Putensen
- Christopher MacIsaac
- Christopher Spradley
- Chuanyun Qian
- Claire Cattigan
- Claire Reynolds
- Clara Laplaza Eva Regidor
- Clara Pacheco
- Claudia Diaz
- Claudia Olvera-Guzman
- Craig A Piquette
- Craig Cernosek
- Crissie De Spirito
- Crissie Despirito
- Cristian Casabella
- Cristian Cevallos
- Cristina Orlandi
- Cristina Santos
- César Antonio Maquilon
- César Aragón
- César Cruz Lozano
- César Pérez-Calvo
- Damian Violi
- Dana K Soetaert
- Daniel Duarte
- Daniel Fontaneda
- Daniel Vargas
- Daniel Weiss
- David Freire
- David Milliss
- Davide Chiumello
- Daxing Yu
- Debiao Song
- Deborah Barge
- Deborah Cook
- Deepak Govil
- Del-Sorbo L.
- Denice Wells
- Dennis Bergmans
- Dhruva Chaudhry
- Di Russo
- Diane Mackle
- Dianne Hill
- Dianne Stephens
- Dietrich Henzler
- Dimitros Matamis
- Dimple Tejwani
- Dinalva Aparecida Gomes
- Do Danh Quynh
- Dolores Vila
- Dongpo Jiang
- Dorothée Carpentier
- Du B.
- Edgard Luna
- Edgardo E Tabhan
- Edgardo Nuñez
- Edoardo De Robertis
- Eduard Bootsma
- Eduardo Almeida
- Eduardo Fonseca Sad
- Edward Nicolayenko
- Eileen Gilder
- Elena Gallego
- Elena Parreño
- Eleni Antoniadou
- Elias Caragna
- Elisa Estenssoro
- Elisha Fulton
- Elisha Matheson
- Ellen Kinkel
- Emily Stern
- Enrique Maraví
- Enrique Piacentini
- Erika Mannelli
- Erin Braden
- Erna Alberts
- Erwin J Oei
- Esteban A
- Eugenio Palazón
- Eva Benveniste
- Eva Manteiga
- Fabien Grelon
- Fabien Soulis
- Fabricio Picoita
- Fachun Zhou
- Falk Hildebrandt
- Fang Xu
- Farhad N Kapadia
- Fausto Fialho Moura
- Federica Antonicelli
- Federica Tallarini
- Federico Gordo
- Fekri Abroug
- Feng Li
- Fernando Antônio Botoni
- Fernando Fernández
- Fernando Lambert
- Fernando Lipovestky
- Fernando Pérez
- Fernando Ríos
- Fernando Saldarini
- Fernando Sánchez
- Fernando Villarejo
- Fernando Villarejo
- Filomena Faria
- Forbes McGain
- Francesca Frigieri
- Francesco Idone
- Francesco Mojoli
- Francisco Criado
- Francisco Guerrero
- Francisco Lucena
- Francisco Manzano
- Francisco Molina
- Francisco Ortuño
- Frank Torres
- Franklin Villegas
- François Collet
- Freddy Sandy
- Freddy Sánchez
- Frederico Costa Val Barros
- Frederico Rodrigues Anselmo
- Frutos-Vivar F.
- Frédéric Bellec
- Félix Lacoma
- Gabriel D Empaire
- Gaetano Perchiazzi
- Gang Li
- Gary Kinasewitz
- Gary Kinasewitz
- Gastón Pittini
- Gaëtan Bedunaeu
- Gee Young Suh
- Gemma Rialp
- Geneva Tatem
- Geng Zhang
- Genis Carrasco
- George Liziamma
- George Lukas
- Gerardo Filippa
- Gilda Diaz-Fuentes
- Gina Quinde
- Giorgia Citterio
- Giorgio Tulli
- Gonzalez M.
- Gonzalo Javier Ríos
- Graciela Elizabeth
- Graciela Franca
- Graeme Duke
- Gregory A Schmidt
- Guillaume Marcotte
- Guillermo Chiappero
- Guillermo Cueto Robledo
- Guillermo Falconí
- Guillermo Muñiz
- Guillermo Ortiz
- Gustavo Badariotti
- Gustavo Jannello
- Gustavo Morales Muñoz
- Gustavo Paredes
- Géraldine Dessertaine
- Haibo Qiu
- Hannah Mathers
- Hans-Henrik Bülow
- Harald Fritz
- Harry P P M Gelissen
- Heinrich Paulus
- Heinz Kerger
- Helen Rodgers
- Helen Wong
- Heloisa Castro
- Henry Caballero
- Hergen Buscher
- Hernan Nunia
- Hernán Nuñez
- Hong Pu
- Hongyang Xu
- Hongyuan Lin
- Howard Connor
- Hugo Capponcelli
- Hugo Urbano
- Hye Sook Choi
- Ian Carrasco
- Ian Moore
- Ian Seppelt
- Ilaria Curro'
- Ilaria Maria Mastromauro
- Imed Chouchene
- Imogen Mitchell
- Ingrid van den Hul
- Ingrid Von der Osten
- Inmaculada Vallverdú
- Irene Aragão
- Irene Dot
- Irene Watpool
- Islem Ouanes
- Ismail Kati
- Itziar Mintegui
- Ivano Aprile
- Jacinto Baena
- Jackeline Coello
- Jan Dittmann
- Jan Friedrich
- Jan Mehrtens
- Jane Thomas
- Janine Dias Alves
- Jasmin Board
- Jasmin Board
- Jasmin Board
- Jason Fletcher
- Javier Blanco
- Javier Castañeda
- Javier Cebrián
- Javier Díaz Domínguez
- Javier García-Alonso
- Javier González-Robledo
- Javier Horacio Álvarez
- Javier Hurtado
- Javier Ladape Martinez
- Javier Ruiz
- Je Hyeong Kim
- Jean-Christophe M Richard
- Jeff Presneill
- Jeffrey Singh
- Jennifer Germain
- Jennifer Goodson
- Jennifer Holmes
- Jennifer Twombley
- Jenny Dennett
- Jens Brushoj
- Jens Buettner
- Jesús Sánchez
- Jesús Sánchez-Ruiz
- Jian Huang
- Jianbiao Meng
- Jianguo Li
- Jianhong Fu
- Jianying Guo
- Jiaqiong Li
- Jibaja M.
- Jin Hwa Lee
- Jin Young An
- Jinghua Wang
- Jiuzhi Zhang
- Joachim Hartung
- Joan Maria Raurich
- Joana Silvestre
- Joanne Sutton
- Jodi Brown
- Johannes Busch
- John Durning
- John Myburgh
- John Oropell
- John Santamaria
- Jorge Arroyo
- Jorge Gerez
- Jorge Vidal Hernández
- Jorgelina Guyon
- Jose Angel Baltazar Torres
- Josep Maria Sirvent
- José Carlos Versiani
- José Claudio Leo
- José Elizalde
- José Francisco López Baca
- José J Blanco
- José Luis Scapellato
- José Manuel Serrano
- José María Gutiérrez
- José María Montón
- José María Nicolás
- José María Quiroga
- José Miguel Guerrero
- José Salinas
- José Salvador Martínez Cano
- Joyce Okahashi
- Juan Carlos
- Juan Carlos Maurelia
- Juan David Uribe
- Juan Diego Jiménez
- Juan Domingo Fernández
- Juan Guerra
- Juan Pablo Sedano
- Juan Ramón Cortés
- Juanxian Gu
- Judi Tai
- Judith Sagardía
- Julia López-Díaz
- Julian Strati
- Julie Smith
- Julio Osorio
- Julio Pontet
- Julián Hernández
- Jun Jin
- Jörg Haberkorn
- Jörn Schlechtweg
- Karina Bonasegla
- Katherine Davidson
- Kathleen Lilli
- Katty Trelles
- Kelly Choy
- Kerry Canady
- Ki-Suck Jung
- Kim Heus
- Konstantinos Raymondos
- Kwan Ming Chit
- Kyung Chan Kim
- Larry Welder
- Laura Jones
- Laura Sayagues
- Laura Wilson
- Laura Álvarez-Montero
- Lauralyn McIntryre
- Laurent Brochard
- Leanne Boehm
- Lei Chen
- Leila Eckholt
- Leonardo Pazmiño
- Leonie Weisbrodt
- Leticia Rapetti
- Liang Pan
- Lidón Mateu
- Liliana Caipe
- Lisa Julien
- Lisandro Betttini
- Loredana Pitagora
- Lori-Ann Kozikowski
- Lucas Vallejo
- Lucia Capilla
- Luis Fernando Castro Castro
- Luis Gonzalez Mosquera
- Luis González Zambrano
- Luis Marina
- Luis Pablo Cardonnet
- Luis Soto-Germani
- Luis Soto-Román
- Luis Williams
- Lutz Pfeiffer
- Lynette Newby
- M Eugenia
- Madhav Gudi
- Madison Dennis
- Maggiore S. M.
- Manoj K Saxena
- Manuel Jibaja
- Manuel Valledor
- Maoqin Li
- Mar Gobernado
- Marc Fabra
- Marc Lipkus
- Marcela Canola-Mazo
- Marcela Granados
- Marcelo Alcântara Holanda
- Marcelo Choque
- Marcelo Ochoa
- Marcelo Palavecino
- Marco Adversi
- Marco Antônio Ribeiro Leão
- Marco Antônio Soares Reis
- Marco Bezzi
- Marco Escobar
- Marco Gonzalez
- Marco González
- Marco Montes De Oca
- Marcos Delgado
- Marcos Juan Zec
- Marcus Ruecker
- Maria Aparecida Braga
- Maria Del Mar Torres-Perez
- Maria Giannakou
- Maria Wussow
- Mariana Monllau
- Marianna Esposito
- Marin M. D. C.
- Marina Busico
- Mario Acosta
- Mario Alonso Treviño Salinas
- Mario Cancela
- Mario Gómez
- Mario Villabon
- Marisol Rodríguez-Goñi
- Mark Bailey
- Mark Tidswell
- Markus Schappacher
- Marta Beron
- Marta Ferrari
- Marta Ugalde
- Martin Deheza
- Martín Lugaro
- Mary La Pine
- María Belén Yapur
- María Del Carmen de la Torre
- María Elena Pérez-Losada
- María Eugenia González
- María Fernanda García
- María Garitacelaya
- María Isabel Ruiz
- María José Tolón
- María Luisa Navarrete
- María Victoria de la Torre
- María Ángeles Alonso
- María Ángeles Pena
- Matamis D.
- Matthew Kirchner
- Matty Koopmans
- Matías Brizuela
- Mauricio Vinzio
- Maurizio Bottiroli
- Maurizio Raineri Santi
- Maurício Meireles Góes
- Maximillian Ragaller
- Mayur Patel
- Medhat Soliman
- Mehar-Un-Nisa Raja
- Mian Chen
- Michael A Kuiper
- Michael Miletin
- Michael Quintel
- Michela Bombino
- Michele Iannuzzi
- Miguel Fernández-Vivas
- Miguel Lazcano
- Miguel León
- Miguel Llano
- Miguel Ángel González-Gallego
- Mijail Játiva
- Mikhail Kirov
- Mikkel Præst
- Minka Springham
- Miquel Ferrer
- Mirko Belliato
- Mohamed A Saad
- Mohammed Al-Jagbeer
- Monica Rocco
- Monika Holler
- Moo Suk Park
- Mounir Bouaziz
- Mourad Amor
- Muriel A.
- Myriam Montalvo
- Myung-Goo Lee
- Nagarajan Ramakrishnan
- Nahit Cakar
- Neill Adhikari
- Nelson Barros
- Nelson Fonseca
- Nelson Medina
- Nghuyen Ba Tuan
- Nguyen Huu Hoang
- Niall Ferguson
- Nicolas Nin
- Nicole Marinoff
- Nicolás Zamboschi
- Nieves Franco
- Nils Marquardt
- Nin N.
- Norberto Tiribelli
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- Norma Beatriz Márquez
- Nuria Alonso
- Oliver Franke
- Olivia Dulfo
- Orla Smith
- Oscar Cluzet
- P Kruska
- P Samaddar
- Pablo Desmery
- Pablo Gómez
- Pang Wing Yan
- Paolo Navalesi
- Pascal Beuret
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- Patricia Albert
- Patricia Jimeno
- Patricia Leung
- Patricia Vogl
- Paul Goldrick
- Paul J Dennesen
- Paul Young
- Paulo Marcal
- Pedro Alzugaray
- Pedro Galdos
- Pedro Jesús Domínguez
- Pedro Rosa
- Pelosi P.
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- Peter van der Voort
- Pham Thi Van Anh
- Phil Alkana
- Philippe Berger
- Pierre-Gildas Guitard
- Prachee Sathe
- Pravin Amin
- Priya Nair
- Qing Song
- Qingyuan Zhan
- Qunmei Yao
- Rachael Parke
- Rachel Whyte
- Rafael Blancas
- Rafael Morales
- Rahul Nanchal
- Raju Pusapati
- Ramiro Puetate
- Raquel Manzanedo
- Raquel Montoiro
- Raquel Yano
- Raymondos K.
- Raúl de Pablo
- Raúl González
- Raúl Lombardi
- Remzi Iscimen
- Ricardo Buitrago
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- Ricardo Matos
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- Rios F.
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- Robyn Klages
- Rodrigo E Gómez-Paz
- Roger Lamoglie
- Rogério de Castro Pereira
- Roland Schneider
- Rolf Dembinski
- Rolf Rossaint
- Rollin Roldán Mori
- Romano Tetamo
- Román Garrido
- Ronald Pairumani
- Ronnie Mantilla
- Rosa Luz López Martínez
- Rosa Sebastián
- Rosa Álvaro
- Rosalba Tufano
- Rosanna Del Giudice
- Rosanna Vaschetto
- Rosario Urbino
- Rovílson Lara
- Rovílson Lara
- Rubens Altair Amaral de Pádua
- Rubén Camargo
- Rui Moreno
- Rupesh Vakil
- Ryan Albert
- Sabriye Guvenc
- Salem Ould Zein
- Salvatore Maurizio Maggiore
- Samer Haj-Bakri
- Samir Abdelhadi
- Samir Sahu
- Samir Vermani
- Sando Chavarria
- Sangeeta Mehta
- Sanjay Dhanuka
- Santiago Ilutovich
- Sara Cabañes
- Schimdt Alejandra
- Sebastian Circo
- Sebastián E Mare
- Serena Azzari
- Serge Heines
- Sergio Cáceres
- Sergio Lasdica
- Seton Henderson
- Shawna Reddie
- Sheila Nainan Myatra
- Shelby Sutton
- Sheree Gare
- Shirley Nelson
- Shouhong Wang
- Silke Frenzel
- Silvia Mareque
- Silvina Borello
- Silvio A Ñamendys-Silva
- Simon J G Hockley
- Simona Beniczky
- Sindhaghatta Venkatram
- Sine Wichman
- Smyth Smith
- Soares M. A.
- Sofía García
- Soraya Puertas
- Srinivas Samavedam
- Stambouli Neji
- Steffen Appel
- Steffen Weber-Carstens
- Stephanie Lubchansky
- Stephen Lapinsky
- Steven Y Chang
- Stevens Salva
- Subhash Kumar Todi
- Sujoy Mukherjee
- Susan Gillen
- Susana Alves Ferreira
- Susana Moradillo
- Susana Temprano
- Susanne Andi Iversen
- Sutherasan Y.
- Sutrisno Gunawan
- Sylvia den Boer
- Tania Caf
- Tarek Dendane
- Tayfun Adanir
- Tejerina E. E.
- Teresa Mut
- Teresa Sánchez de Dios
- Thille A. W.
- Thomas Bein
- Thomas Lipp
- Thomas Moellhoff
- Thomas Steinke
- Thoralf Kerner
- Tiehe Qin
- Tim Coles
- Tim Houlihan
- Timothy D Girard
- Tom Cowlam
- Tony Sutherland
- Tony Williams
- Travis Parry
- Troy Browne
- Tumbass Volker
- Uli Strauch
- Umesh G
- Unase Büyükkoçak
- V J Cardenas Jr
- Valentín Parra
- Valerio Mangani
- Valery Subbotin
- Valle Pinheiro B.
- Valéria de Carvalho Magela
- Vanesa Ramírez
- Vicente Arraez
- Victoria Goñi
- Vincent John Scott
- Vito Marco Ranieri
- Vivek Joshi
- Wajdi Maazouzi
- Walter Brandt
- Walter Seyde
- Wanxia Li
- Wei He
- Wei Yu
- Wei Zhang
- Weihai Yao
- William Rodriguez-Cintron
- Winfried Schubert
- Wolfgang Baier
- Won-Yeon Lee
- Xi Zhu
- Xianyao Wan
- Xiaobo Huang
- Xue Wang
- Yalin Liu
- Yan Kang
- Yangong Chao
- Yaseen Arabi
- Yi Li
- Yi Yang
- Yogeet Kaur
- Yongjie Yin
- Young Suh G.
- Younsuck Koh
- Yu Bai
- Yuan Xu
- Yuhong Guo
- Yun Seong Kim
- Yunxuan Yue
- Zafer Dogan
- Zalatiel Maycotte Luna
- Zaza Cohen
- Zhengxuan Lv
- Zhenjie Hu
- Zhenyang He
- Zhicheng Zhang
- Zhihua Hu
- Zhixiang Li
- Zoltan Szentkereszty
- Zoraida Parra
- Zsolt Molnar
- Ángela Alonso
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/11/2021
- Field of study
OBJECTIVES: To describe the changes in ventilator management over time in patients with neurologic disease at ICU admission and to estimate factors associated with 28-day hospital mortality. DESIGN: Secondary analysis of three prospective, observational, multicenter studies. SETTING: Cohort studies conducted in 2004, 2010, and 2016. PATIENTS: Adult patients who received mechanical ventilation for more than 12 hours. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Among the 20,929 patients enrolled, we included 4,152 (20%) mechanically ventilated patients due to different neurologic diseases. Hemorrhagic stroke and brain trauma were the most common pathologies associated with the need for mechanical ventilation. Although volume-cycled ventilation remained the preferred ventilation mode, there was a significant (p < 0.001) increment in the use of pressure support ventilation. The proportion of patients receiving a protective lung ventilation strategy was increased over time: 47% in 2004, 63% in 2010, and 65% in 2016 (p < 0.001), as well as the duration of protective ventilation strategies: 406 days per 1,000 mechanical ventilation days in 2004, 523 days per 1,000 mechanical ventilation days in 2010, and 585 days per 1,000 mechanical ventilation days in 2016 (p < 0.001). There were no differences in the length of stay in the ICU, mortality in the ICU, and mortality in hospital from 2004 to 2016. Independent risk factors for 28-day mortality were age greater than 75 years, Simplified Acute Physiology Score II greater than 50, the occurrence of organ dysfunction within first 48 hours after brain injury, and specific neurologic diseases such as hemorrhagic stroke, ischemic stroke, and brain trauma. CONCLUSIONS: More lung-protective ventilatory strategies have been implemented over years in neurologic patients with no effect on pulmonary complications or on survival. We found several prognostic factors on mortality such as advanced age, the severity of the disease, organ dysfunctions, and the etiology of neurologic disease