664 research outputs found
Talent Retention and Organizational Performance: A Competitive Positioning in Nigerian Banking Sector
The study examined how best an organization can retain and
manage talented employees to ensure survival and growth
in the banking industry. The descriptive research design was
adopted. The survey sample size was one hundred and eighty
five (185) and was analysed as a whole. Self-administered
questionnaire was adopted in order to obtain adequate and
valid data for the study and the responses obtained were subjected
to some analyses with the use of Statistical Package for
Social Sciences (SPSS) AMOS 21, with the adoption of Structural
Equation Modelling (SEM) to obtain correlation between
observed variables and also regression between the dependent
and independent constructs of the study. However, the results
from the survey indicate that pay has positive significant implications
on employees’ commitment and involvement. This suggests
that decision makers should incorporate these variables
(salary, bonus, incentives, reward, and profit sharing) into their
employment relation strategies and policies which ultimately
lead to increase the level of commitment and involvement
among the employees
DC to AC Inverter for a Microgrid-Inspired Power Distribution Architecture for Electric Vehicles
This project builds upon the prototyping of a microgrid-inspired power distribution architecture for electric vehicles (EVs). The efficacy of this prototype aims to inform a full-scale power distribution system that charges an EV battery, supports the electric grid with important ancillary services, performs peer-to-peer EV charging, and works in conjunction with other AC and DC sources and loads. The scope of this report focuses specifically on the design, construction, and testing of the DC/AC inverter. Future development of this distribution architecture will incorporate synchronous generators, a battery management system, and an Arduino/Raspberry Pi-based communication system to fully simulate an electric vehicle’s design
Effects of reflux laryngitis on laryngeal chemoreflexes in newborn lambs
It has been suggested that reflux laryngitis (RL) is involved in apneas-bradycardias of the newborn. The aim of the present study was to develop a unique RL model in newborn lambs to test the hypothesis that RL enhances the cardiorespiratory components of the laryngeal chemoreflexes (LCR) in the neonatal period. Gastric juice surrogate (2 ml of normal saline solution with HCl pH 2 + pepsin 300 U/ml) (RL group, n = 6) or normal saline (control group, n = 6) was repeatedly injected onto the posterior aspect of the larynx, 3 times a day for 6 consecutive days, via a retrograde catheter introduced into the cervical esophagus. Lambs instilled with gastric juice surrogate presented clinical signs of RL, as well as moderate laryngitis on histological observation. Laryngeal chemoreflexes were thereafter induced during sleep by injection of 0.5 ml of HCl (pH 2), ewe's milk, distilled water or saline into the laryngeal vestibule via a chronic, transcutaneous supraglottal catheter. Overall, RL led to a significantly greater respiratory inhibition compared with the control group during LCR, including longer apnea duration (P = 0.01), lower minimal respiratory rate (P = 0.002), and a more prominent decrease in arterial hemoglobin saturation (SpO(2)) (P = 0.03). No effects were observed on cardiac variables. In conclusion, 1) our unique neonatal ovine model presents clinical and histological characteristics of RL; and 2) the presence of RL in newborn lambs increases the respiratory inhibition observed with LCR, at times leading to severe apneas and desaturations
Comparative Analyses And Structural Insights Of The Novel Cytochrome P450 Fusion Protein Family CYP5619 In Oomycetes
Published ArticlePhylogenetic and structural analysis of P450 proteins fused to peroxidase/dioxygenase has not
been reported yet. We present phylogenetic and in silico structural analysis of the novel P450 fusion
family CYP5619 from the deadliest fish pathogenic oomycete, Saprolegnia diclina. Data-mining and
annotation of CYP5619 members revealed their unique presence in oomycetes. CYP5619 members
have the highest number of conserved amino acids among eukaryotic P450s. The highest number
of conserved amino acids (78%) occurred in the peroxidase/dioxygenase domain compared to the
P450 domain (22%). In silico structural analysis using a high-quality CYP5619A1 model revealed
that CYP5619A1 has characteristic P450 structural motifs including EXXR and CXG. However, the
heme-binding domain (CXG) in CYP5619 members was found to be highly degenerated. The in silico
substrate binding pattern revealed that CYP5619A1 have a high affinity to medium chain fatty acids.
Interestingly, the controlling agent of S. diclina malachite green was predicted to have the highest
binding affinity, along with linoleic acid. However, unlike fatty acids, none of the active site amino
acids formed hydrogen bonds with malachite green. The study’s results will pave the way for assessing
CYP5619A1’s role in S. diclina physiology, including the nature of malachite green binding
Large scale physical modeling synthesis, parallel computing, and musical experimentation:The NESS Project
Increased resting hippocampal and basal ganglia perfusion in people at ultra high risk for psychosis: replication in a second cohort
Hyperspherical partial wave calculation for double photoionization of the helium atom at 20 eV excess energy
Hyperspherical partial wave approach has been applied here in the study of
double photoionization of the helium atom for equal energy sharing geometry at
20 eV excess energy. Calculations have been done both in length and velocity
gauges and are found to agree with each other, with the CCC results and with
experiments and exhibit some advantages of the corresponding three particle
wave function over other wave functions in use.Comment: 11 pages, 1 figure, submitted to J. Phys B: At. Mol. Opt. Phys; v2 -
revised considerably, rewritten using ioplatex clas
Effects of reflux laryngitis on non-nutritive swallowing in newborn lambs
Reflux laryngitis in infants may be involved not only in laryngeal disorders, but also in disorders of cardiorespiratory control through its impact on laryngeal function. Our objective was to study the effect of reflux laryngitis on non-nutritive swallowing (NNS) and NNS-breathing coordination. Two groups of six newborn lambs, randomized into laryngitis and control groups, were surgically instrumented for recording states of alertness, swallowing and cardiorespiratory variables without sedation. A mild to moderate reflux laryngitis was induced in lambs from the experimental group. A significant decrease in the number of NNS bursts and apneas was observed in the laryngitis group in active sleep (p=0.03). In addition, lower heart and respiratory rates, as well as prolonged apnea duration (p<0.0001) were observed. No physiologically significant alterations in NNS-breathing coordination were observed in the laryngitis group. We conclude that a mild to moderate reflux laryngitis alters NNS burst frequency and autonomous control of cardiac activity and respiration in lambs
Explaining semantic short-term memory deficits:evidence for the critical role of semantic control
Patients with apparently selective short-term memory (STM) deficits for semantic information have played an important role in developing multi-store theories of STM and challenge the idea that verbal STM is supported by maintaining activation in the language system. We propose that semantic STM deficits are not as selective as previously thought and can occur as a result of mild disruption to semantic control processes, i.e., mechanisms that bias semantic processing towards task-relevant aspects of knowledge and away from irrelevant information. We tested three semantic STM patients with tasks that tapped four aspects of semantic control: (i) resolving ambiguity between word meanings, (ii) sensitivity to cues, (iii) ignoring irrelevant information and (iv) detecting weak semantic associations. All were impaired in conditions requiring more semantic control, irrespective of the STM demands of the task, suggesting a mild, but task-general, deficit in regulating semantic knowledge. This mild deficit has a disproportionate effect on STM tasks because they have high intrinsic control demands: in STM tasks, control is required to keep information active when it is no longer available in the environment and to manage competition between items held in memory simultaneously. By re-interpreting the core deficit in semantic STM patients in this way, we are able to explain their apparently selective impairment without the need for a specialised STM store. Instead, we argue that semantic STM patients occupy the mildest end of spectrum of semantic control disorders
Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis
This article was originally published under NPG’s License to Publish, but has now been made available under a [CC BY 4.0] license. The PDF and HTML versions of the paper have been modified accordingly.</p
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