1,458 research outputs found

    Experimental Investigation of the NASA Common Research Model with a Natural Laminar Flow Wing in the NASA Langley National Transonic Facility

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    A test of the new NASA Common Research Model with a Natural Laminar Flow (CRMNLF) semispan wing in the NASA Langley National Transonic Facility (NTF) was completed in October 2018. The main focus of this test was the evaluation of the extent of laminar flow on the CRM-NLF wing at various Reynolds numbers and test conditions. During this test, data were acquired at chord Reynolds numbers from 10 to 30 million and at Mach numbers ranging from 0.84 to 0.86. This investigation provided valuable insight into the necessary procedures for laminar flow testing in the NTF. It also significantly advanced the new carbonbased heating layer technique to improve the quality of transition visualization data from temperature sensitive paint (TSP) in a cryogenic wind tunnel

    Galois representations attached to automorphic forms on GL_2 over CM fields

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    In this paper we generalize the work of Harris-Soudry-Taylor and construct the compatible systems of two-dimensional Galois representations attached to cuspidal automorphic representations of cohomological type on GL_2 over a CM field with a suitable condition on their central characters. We also prove a local-global compatibility statement, up to semisimplification.Comment: 61 page

    Preliminary Results from an Experimental Assessment of a Natural Laminar Flow Design Method

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    A 5.2% scale semispan model of the new Common Research Model with Natural Laminar Flow (CRM-NLF) was tested in the National Transonic Facility (NTF) at the NASA Langley Research Center. The model was tested at transonic cruise flight conditions with Reynolds numbers based on mean aerodynamic chord ranging from 10 to 30 million. The goal of the test was to experimentally validate a new design method, referred to as Crossflow Attenuated NLF (CATNLF), which shapes airfoils to have pressure distributions that delay transition on wings with high sweep and Reynolds numbers. Additionally, the test aimed to characterize the NTF laminar flow testing capabilities, as well as establish best practices for laminar flow wind tunnel testing. Preliminary results regarding the first goal of validating the new design method are presented in this paper. Experimental data analyzed in this assessment include surface pressure data and transition images. The surface pressure data acquired during the test agree well with computational fluid dynamics (CFD) results. Transition images at a variety of Reynolds numbers and angles of attack are presented and compared to computational transition predictions. The experimental data are used to assess transition due to a turbulent attachment line, as well as crossflow and Tollmien-Schlichting modal instabilities. Preliminary results suggest the CATNLF design method is successful at delaying transition on wings with high sweep. Initial analysis of the transition front images showed transition Reynolds numbers that exceed historic experimental values at similar sweep angles. , section lif

    Predictors of Maternal Parental Self-Efficacy Among Primiparas in the Early Postnatal Period

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    10.1177/0193945914537724Western Journal of Nursing Researc

    Reporting on covariate adjustment in randomised controlled trials before and after revision of the 2001 CONSORT statement: a literature review

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    Objectives: To evaluate the use and reporting of adjusted analysis in randomised controlled trials (RCTs) and compare the quality of reporting before and after the revision of the CONSORT Statement in 2001. Design: Comparison of two cross sectional samples of published articles. Data Sources: Journal articles indexed on PubMed in December 2000 and December 2006. Study Selection: Parallel group RCTs with a full publication carried out in humans and published in English Main outcome measures: Proportion of articles reported adjusted analysis; use of adjusted analysis; the reason for adjustment; the method of adjustment and the reporting of adjusted analysis results in the main text and abstract. Results: In both cohorts, 25% of studies reported adjusted analysis (84/355 in 2000 vs 113/422 in 2006). Compared with articles reporting only unadjusted analyses, articles that reported adjusted analyses were more likely to specify primary outcomes, involve multiple centers, perform stratified randomization, be published in general medical journals, and recruit larger sample sizes. In both years a minority of articles explained why and how covariates were selected for adjustment (20% to 30%). Almost all articles specified the statistical methods used for adjustment (99% in 2000 vs 100% in 2006) but only 5% and 10%, respectively, reported both adjusted and unadjusted results as recommended in the CONSORT guidelines. Conclusion: There was no evidence of change in the reporting of adjusted analysis results five years after the revision of the CONSORT Statement and only a few articles adhered fully to the CONSORT recommendations

    EDI control : management and audit issues

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    https://egrove.olemiss.edu/aicpa_guides/1419/thumbnail.jp

    Sibling comparisons elucidate the associations between educational attainment polygenic scores and alcohol, nicotine and cannabis.

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    Background and aimsThe associations between low educational attainment and substance use disorders (SUDs) may be related to a common genetic vulnerability. We aimed to elucidate the associations between polygenic scores for educational attainment and clinical criterion counts for three SUDs (alcohol, nicotine and cannabis).DesignPolygenic association and sibling comparison methods. The latter strengthens inferences in observational research by controlling for confounding factors that differ between families.SettingSix sites in the United States.ParticipantsEuropean ancestry participants aged 25 years and older from the Collaborative Study on the Genetics of Alcoholism (COGA). Polygenic association analyses included 5582 (54% female) participants. Sibling comparisons included 3098 (52% female) participants from 1226 sibling groups nested within the overall sample.MeasurementsOutcomes included criterion counts for DSM-5 alcohol use disorder (AUDSX), Fagerström nicotine dependence (NDSX) and DSM-5 cannabis use disorder (CUDSX). We derived polygenic scores for educational attainment (EduYears-GPS) using summary statistics from a large (> 1 million) genome-wide association study of educational attainment.FindingsIn polygenic association analyses, higher EduYears-GPS predicted lower AUDSX, NDSX and CUDSX [P < 0.01, effect sizes (R2 ) ranging from 0.30 to 1.84%]. These effects were robust in sibling comparisons, where sibling differences in EduYears-GPS predicted all three SUDs (P < 0.05, R2 0.13-0.20%).ConclusionsIndividuals who carry more alleles associated with educational attainment tend to meet fewer clinical criteria for alcohol, nicotine and cannabis use disorders, and these effects are robust to rigorous controls for potentially confounding factors that differ between families (e.g. socio-economic status, urban-rural residency and parental education)
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