9 research outputs found
An MR-compatible antenna and application in a murine superficial hyperthermia applicator
- Author
- Publication venue
- 'Informa UK Limited'
- Publication date
- 13/09/2017
- Field of study
In this work, a novel magnetic resonance (MR)-compatible microwave antenna was designed and validated in a small animal superficial hyperthermia applicator. The antenna operates at 2.45 GHz and matching is made robust against production and setup inaccuracies. To validate our theoretical concept, a prototype of the applicator was manufactured and tested for its properties concerning input reflection, sensitivity for setup inaccuracies, environment temperature stability and MR-compatibility. The experiments show that the applicator indeed fulfils the requirements for MR-guided hyperthermia investigation in small animals: it creates a small heating focus (<1 cm3), has a stable and reliable performance (S11< −15 dB) for all working conditions and is MR-compatible
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
- Author
- A. Mohammed Kalakwa
- A. Nemer Ayoub
- Abantanga Francis A.
- Abatli Safa' Jamal
- Abbas Wisam
- Abbo Olivier
- Abdelbaqi Reem
- Abdelhady Dina Sobhy
- Abdelhafez Mohammad Omar Mohammad
- Abdelhamid Sultan S.
- Abdelmaksoud Sherif
- Abdelmoumen Roua
- Abdelmutalib Fakereldeen
- Abdul-Mumin Alhassan
- Abduljawad Fatima Mousa
- Abdullah Fizan
- Abdullah Mohd Yusof bin
- Abdulraheem Nurudeen
- Abdulrahman Alaa
- Abdulsalam Moruf Adekunle
- Abdunomonovich Dekhkonboev Avazjon
- Aboelela Ahmed
- Abouheba Mohamed
- Abrahamsson Kate
- Abrunhosa Matias Marcia
- Abu-Nejmah Fawzi
- Abuajaila Abdulsalam
- Abuattaya Adham Ashraf
- Abubakar Auwal M
- Abueideh Ahmad
- Abuhayyeh Husam Aldean
- Abuhlega Ma'aly A.
- Abukhalaf Sadi
- Abumunshar Ali Abdelhay
- Acuna Gaston
- Adams Stephen
- Adamu Sani
- Adanan Mohd Fitri Shukri bin Mohamed
- Adawi Ihda
- Adawi Samer
- Adawy Ahmad
- Ade-Ajayi Niyi
- Adegboyega Rilwan
- Ademuyiwa Adesoji
- Adesanya Opeoluwa
- Adhiwidjaja Cathline Freya
- Adofo-Ansong Nana
- Agboola Titiloye Hannah
- Agelebe Efeturi
- Aguilar Aguilar Faye
- Aguilar Gargurevich Prince Pamela
- Aguirre-Lopez Pastor
- Agulham Miguel Angelo
- Ahmad Hira
- Ahmad Zahidah Adlynee Haji
- Ahmed Hazem
- Ahmed Mahmoud Abdelfattah
- Ajai Olalekan Temitope
- Ajao Emmanuel Akinlabi
- Ajiboye Olalekan S.
- Ajrami Yara
- Ajwa Ahmad Elian Abu
- Akan M. Eren
- Akhbari Melika
- Akhter Nadeem
- Akova Fatih
- Al-Attar Hala M.
- Al-Halbouni Layana
- Al-Mamun Abdullah
- Al-Mayoof Ali Farooq
- Al-Momani Hashem M.
- Al-Mouakeh Ahmad
- Al-Rayyes Maisara
- Al-saleem Hasan Subhi Hasan Abu
- Al-Salhi Ashraf Ayman
- Al-Shwaikh Samar H.
- Al-Slaibi Ibrahim
- Al-Taher Raed Nael
- Al-Taher Raed Nael
- Al-Tammam Hiba
- Alakaloko Felix
- Alamrain Abdulwhhab Ayman Abu
- Alanguia Chipana Cathy Lee
- Alattas Khalid
- Alberto Carlos
- Albozidi Aya
- Alcántara Elvyn
- ALDIRAWI MOHAMMED A. M.
- Alebbini Mohanad Mutasem
- Alfoghi Mabroka
- Algabri Hayder Nadhim Obaid
- Alglaib Mohammed Meftah
- Alhamid Ahmad
- Alhamid Aos
- Alhassan Priscilla
- Ali Hassan
- Ali Karim Osamy
- Ali Liza
- Ali Mansour
- Alijla Sharif
- Alijla Sharif S.
- Aliwisat Ahmad Hasan
- Aljaboo Hajir
- Aljadidi Wesal Omar F. Saied
- Aljarad Ziad
- Alkareem Raghad mohammad abdu
- Almada Suad Ahmed
- Almadhoun Walaa
- Almasri Murad
- Almeida Aguiar Arthur
- Almeida Giovana
- Almengar Inas
- Almohamady Hisham
- Almosaibli Mohammad
- Almusleh Tasneem Fathi Hasan
- Alnaeri Ali
- Alnahhal Khaled
- Alonso Verónica
- Alosta Hasan Mustafa
- Alqarajeh Firas
- Alqor Mohammad Omar Ibrahim
- Alsaadi Nijmeh Nasser
- Alsaggaf Ameen
- Alsaied Amer
- Alser Mohammed
- Alser Osaid H.
- Alshaikhkhalil Haya Abdulnasser Ali
- Alshehri Abdullah
- Altaweel Ahmed
- Altın Merve
- Altokhais Tariq
- Altomi Mohamed
- Alturki Fahad
- Alvarado Zelada Jackelyne
- Alves Dutra da Silva Érika
- Alwadia Soha Marwan Salem
- Alwaggaa Nouriyah Ali
- Alzamari Ainaa Ata Mohammad
- Alzate Gallego Edgar
- Alzeer Asmahan Mohammad Suliman
- Alzerei Sulaiman T.
- Alzraikat Sayel H.
- Alzubair Afnan
- Alzughayyar Tareq Z.
- Amad Mohamed
- Amado Fernando
- Amaechi Chukwubinyelum
- Amah Christopher Chim
- Amarin Justin Z.
- Amarin Marzouq
- Ambriz-González Gabriela
- Ameh Emmanuel
- Amjad Muhammad Bin
- Amoabin Afua Amoabin
- Anatole Nzanzu
- Anatole Nzanzu Kipata
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- Anaya Firas
- Andrade Jerhy
- Andreussi Lorna
- Anicama Elias Rocio
- Annajjar Mohammad hasan
- Anntinea Jessmine
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- Antunez-Mora Alexandra
- Anyomih Theophilus Teddy Kojo
- Anzelewicz Stefan
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- Appeadu-Mensah William
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- Arnaud Alexis P
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- Atatri Yazid yousef mahmoud
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- dos Santos Dias André Iván Bradley
- Dosselman Luke J.
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- Jabang John N.
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- Løfberg Katrine
- M. Ballah Abubakar
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- Machemedze Solomon
- Madieh Jomana
- Madziba Sanele
- Mahmoud Ahmed Mokhtar
- Mahmud Khalid
- Mahmud Refoyez
- Mairami Amsa B.
- Maistry Niveshni
- Makhmud Aliev
- Malcius Dalius
- Malik Janan
- Malik Sawazen
- Mancera Juliana
- Mangray Hansraj
- Manirambona Emery
- Manjira Emmanuel
- Manni Francesco
- Mansfield Sara
- Mansour Islam
- Mansour Mohamed Awad
- Marcos Dolores
- Marianella Depetrini
- Marmol Monica
- Marta Osowicka
- Martin Aranda Diego
- Martin Benjamin
- Martinez-Leo Bruno
- Martins Bianca M. R.
- Martínez Hernández Magro Nestor
- Mary Koshy Roshine
- Massry Nasrallah Ashraf Al
- Matour Bashar M.
- Mayaleh Abdelrazzaq Abu
- Mbonicura Jean Claude
- Mbonisweni Akhona
- Mccluney Simon
- McColl Makepeace Lydia
- Medard Pablo
- Meftah Asma
- Melo Gallindo Rodrigo
- Meloche-Dumas Léamarie
- Mena Adriana
- Mendez Benavente Carolina
- Mendoza Chiroque Carlos
- Mendoza Leon Nancy Rossana
- Mendoza Oviedo Juan Jose
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- Mercado Pedro
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- Merwe Elmarie vd
- Mesas Burgos Carmen
- Mesic Amira
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- Middleton Thomas
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- Milisic Emir
- Millán Carolina
- Miriam Ann
- Mironescu Aurel
- Mirza Muhammad Bilal
- Misk Rami Anwar
- Mitul Ashrarur
- Mitul Ashrarur Rahman
- Modekwe Victor
- Modi Varun
- Mohammad Mohammad Aminu
- Mohammed Abobaker
- Mohammed Azhar Arabi
- Mohammed Hanan Mahmoud
- Mohammed Mansour Mkayed
- Mohammed Ola Ahmed Abdulmjeed
- Moitt Natalie
- Molina Vazquez Maria Elena
- Molina Marcelo
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- Montalvo Marin Arturo
- Montoya Debora
- Mora Maria
- Moraes Mario
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- Morales Otto
- Moreno Maria Eugenia
- Moriya Eliane
- Morjan Mohammed
- Mose Moraa
- Motee Jethishka
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- Saad Alshaimaa M.
- Saad Mahmoud M.
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- Saleem Muhammad
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- Salinas Barreto Juan Jose
- Salinas Vicente
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- Vasquez Matos Juan Pedro
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- Vianney Butoyi Jean Marie
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- Vidal Cristian R. Zalles
- Vierboom Liam
- Villalba Villalba Araceli
- Villegas Silva Raúl
- Vinskaite Asta
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- Vosoughi Armin
- Wafa Tamer
- Walker Gregor
- Wang Jinhu
- Wang Peng
- Waseem Basma
- Weeratunga Naveen
- Weiszewsk Alicja
- Wen Gang
- Werneck Raposo Juliana
- Wester Tomas
- Wijekoon Naveen
- Wilke Alexandra
- Williams Isabelle
- Williams Omolara
- Williams Regan
- Win Win Sabai Phyu
- Wishah Bisan D. M.
- Wishah Nidal
- Wissanji Hussein
- Wolak Przemyslaw
- Wolny Agnieszka
- Wong Janice
- Wong Marilyn
- Wright Naomi Jane
- Wu Guowei
- Wyrzykowski Dariusz
- Xiaodong Guo
- Xie Hua
- Yacoub Mina A.
- Yaghi Bashar
- Yaghi Dua Hasan
- Yalcinkaya Ali
- Yang Hee-Beom
- Yanis Ahmad H.
- Yanowsky Reyes Guillermo
- Yao Yang
- Yapo Benjamin
- Yarza Fernández Jessica
- Yeniay Aslı Öztürk
- Yola Mariya Mukhtar
- Yong Feng
- Youn Joong Kee
- Yousuf Hina
- Yu Mengnan
- Yu Raisa
- Yuen Quah Soong
- Yuldashev Rustam Z.
- Yunus Aayenah
- Za'nouneh Faris J. Abu
- Zaghlol Louay Y.
- Zahari Dato' Dr Zakaria bin
- Zain Mostafa
- Zaman Azrina SK
- Zanellato Josiane Bernartt
- Zarwawi Ahmad Zulhisyam bin
- Zea-Salazar Luis Enrique
- Zeinelabdeen Ali
- Zhao Xiaoxia
- Zhu Jianming
- Zhu Libin
- Zidan Mazen
- Zivanovic Dragoljub
- Zottis Barcelos Fabricio
- Zreeg Dafer abdulhakim . S.
- Zurikat Rajai O.
- Zvizdic Nada
- Zvizdic Zlatan
- Çekiç Bahanur
- Çelik Müge
- Özçelik Zerrin
- Şeref Kıvanç
- Šafus Antonín
- Škvařil Jan
- Štichhauer Radek
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Summary
Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally.
Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies
have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of
the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income
countries globally, and identified factors associated with mortality.
Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to
hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis,
exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a
minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical
status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary
intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause,
in-hospital mortality for all conditions combined and each condition individually, stratified by country income status.
We did a complete case analysis.
Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital
diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal
malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome
countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male.
Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3).
Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income
countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups).
Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome
countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries;
p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients
combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11],
p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20
[1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention
(ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety
checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed
(ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of
parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65
[0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality.
Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome,
middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will
be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger
than 5 years by 2030
Impact of the COVID-19 pandemic on patients with paediatric cancer in low-income, middle-income and high-income countries: a multicentre, international, observational cohort study
- Author
- A K M Khairul Basher
- A M Umar
- Abdallah Elshenawy
- Abdallah R Allam
- Abdelbasit Ali
- Abdeljawad Mazloum
- Abdelrahman Azzam
- Abdelrahman Azzam
- Abdelrahman Bahaa
- AbdulBasit Fehintola
- Abdullah Eldaly
- Abdullahi Nuhu-Koko
- Abdulrahman Almjersah
- Abdulrahman Ghassan Qasem
- Abdulrahman Omar Taha
- Abdulrahman Omar Taha
- Abdulrasheed A Nasir
- Abdurahaman Aremu
- Abiodun Folashade Adekanmbi
- Abiodun Idowu Okunlola
- Abubakari Bawa Abdulai
- Ademola A Adeyeye
- Adeseye M Akinsete
- Adesoji Ademuyiwa
- Adesoji O Ademuyiwa
- Adewumi B Oyesakin
- Adnan Dağçınar
- Agata Chylinska
- Agnes Vojcek
- Agnes Vojcek
- Ahmad Al Ayed
- Ahmad Bouhuwaish
- Ahmad Mansour
- Ahmed Saleh
- Ahmed Samir
- Ahmed Sherif
- Ahmed Tawheed
- Ahmed Y Azzam
- Ahsan Nadeem
- Aishah Mughal
- Aishwarya Ashwinee
- Ajiboye L Olalekan
- Akila Muthukumar
- Akm Amirul Morshed
- Akram Ahmed
- Al-Mudeer Ali
- Alaa Ahmed
- Alaa Hamdan
- Alaa Hamdan
- Alan Siegel
- Alege Abdurrzzaq
- Aleksandar Stanimirovic
- Aleksandra Paunovic
- Alexander S Roth
- Alexandra Valetopoulou
- Alexandre Dukundane
- Alhassan Abdul-Mumin
- Ali Abodest
- Ali Alelayan
- Ali Hammed
- Almahmod Alkhalil
- Almed Moussa
- Alonja Reiter
- Alqasim Abdulkarim
- Alzhraa Salah Abbas
- Amani Alamre
- Amanpreet Brar
- Amer Harky
- Aminat Akinoso
- Aminu Muhammed Umar
- Ammar Al-Basiti
- Ammar Ayman
- Ammar Ayman
- Ammar Omran
- Amon Ngongola
- Amon Ngongola
- Amos Hp Loh
- Amr Mohammed Elsayed Yousf
- Andrea Hayes-Jordan
- Andrea Mingoli
- Andreea C Matei
- Andrew Nwankwo Osuigwe
- Anette S Jacobsen
- Anfel Bouderbala
- Anfel Bouderbala
- Anjan Madasu
- Anna Casey
- Anna Maria Testi
- Anneqa Tahir
- Annette Jacobsen
- Annika Heuer
- Aouabed Nesrine
- Aouabed Nesrine
- Arda Isik
- Ariana Axiaq
- Arissa Ikeda
- Arkha Yasser
- Armin Nazari
- Arshiya Adhnon
- Ashfaque Nabi
- Ashrarur Rahman Mitul
- Ashrarur Rahman Mitul
- Asim Noor Rana
- Asim Noor Rana
- Asimina Galli-Tsinopoulou
- Asmaa A M Albanna
- Assimina Galli-Tsinopoulou
- Athanasios Tragiannidis
- Atiqa Amirali
- Aubrey L Pagaduan
- Augusto Zani
- Augusto Zani
- Aya Sabry Mortada
- Aya Zazo
- Ayah Al Shraideh
- Ayah Bassam Ibrahim
- Ayat M Saadeldin
- Ayesha Mehmood
- Ayesha Saleem
- Ayman Meelad
- Ayten Saraçoğlu
- Azad Patel
- Azrina Syarizad Khutubul
- Baba Jibrin
- Bardisan Gawarieh
- Bechri Hajar
- Bekir Can Kendirlioglu
- Benjamin Martin
- Benjamin Martin
- Benjamin Shou
- Biobele J Brown
- Bioud Belkacem
- Bouaoud Souad
- Boutheyna Drid
- Brahim Saada
- Brian T Craig
- Bruce Bvulani
- Bruno Cirillo
- C-Khai Loh
- Calogero Virgone
- Can Kıvrak
- Catherine Dominic
- Catherine Yang
- Chan Hon Chui
- Charlotte Smith
- Chisom Adaobi Nri-Ezedi
- Christine Nitschke
- Christopher O Bode
- Christopher S Lukong
- Danelle Erwee
- Danica Grujicic
- Daniel Rhee
- Daniel Robinson
- Darica Au
- Dauda E Suleiman
- Dave R Lal
- Dayang Anita Abdul Aziz
- Dayang Anita Abdul Aziz
- Denis Cozzi
- Dennis Mazingi
- Dhruv Nath Ghosh
- Dhruv Nath Ghosh
- Diella Munezero
- Divya Parwani
- Doris Lau
- Dragana Janic
- Duha Jasim
- Dupe S Ademola-Popoola
- Edamisan O Temiye
- Edmund M Der
- Ehab Alameer
- Ehab Alameer
- Ehab El Refaee
- Ehab Hanafy
- Ekram Sharashi
- El Ouahabi Abdessamad
- Elaine Carrolan
- Eleni Tsotridou
- Elif Akova
- Elliott H Taylor
- Elvercio Pereira de Oliveira Junior
- Eman Abdulwahed
- Eman Ibrahim Hager
- Eman Salem Muftah Burzeiza
- Eman Seif Alnaser Solimam
- Emily Christison-Lagay
- Emmanuel A Ameh
- Emmanuel Hatzipantelis
- Emmanuel Uwiringiyimana
- Eric Mwangi Irungu
- Eric Okechukwu Umeh
- Eric W Etchill
- Essam Elhalaby
- Evren Aydogmus
- Ezekiel I Ajayi
- Fabianne Altruda de Moraes Costa Carlesse
- Fabiola Leonelli Diz
- Fakher Rahim
- Farah Sameer Yahya
- Faris Abu Za'nouneh
- Faris Ayasra
- Faris Ayasra
- Fashie Andrew Patrick
- Fatema Naser Al Fayez
- Fatema Sayed
- Fatima Ambreen Imran
- Fatma Mohammed Masoud
- Fatma Saleh Benkhial
- Fatumata Jalloh
- Fayza Haider
- Fayza Haider
- Felix M Alakaloko
- Fernanda Ferreira da Silva Lima
- Fernanda Kelly Marques de Souza
- Fernanda Lobo
- Francesco Pata
- Francis A Abantanga
- Francis Abantanga Georgios Tsoulfas
- Gabriela Guillén
- Gaetano Gallo
- Gamal Amira
- George C Ihediwa
- Ghazwani Salman
- Ghazwani Salman
- Ghazwani Yahia
- Ghita Chaoui
- Gilbert B Bonsaana
- Gioia Brachini
- Global Health Research Group on Children’s Non-Communicable Diseases Collaborative: Soham Bandyopadhyay
- Guido Seitz
- Gul Kalra
- Gul Kalra
- Gustavo Mendonça Ataíde Gomes
- Gül Nihal Özdemir
- Gül Çakmak
- Hafeez Abdelhafeez
- Hajar Benaouda
- Hajar Moujtahid
- Hajier Salim Alrashed
- Halwani Yaninga Fuseini
- Hamidah Alias
- Hamza AlNaggar
- Hani Humad
- Harmit Ghattaura
- Hassan Alalami
- Hazim Ababneh
- Hazim Elfatih
- Heidi Barola
- Helga Nauhaus
- Hend Mohammed Masoud
- Hessissen Laila
- Hira Khalid Zuberi
- Hira Zuberi
- Hoda Tawel
- Hritik Nautiyal
- Humaida Hemlae
- Hytham K S Hamid
- Ibiyeye Taiye Taibat
- Ibrahim Sallam
- Ibukunolu Olufemi Ogundele
- Igor Lazic
- Igor Lima Buarque
- Imane Ammouze
- Imogen Harrison
- Isaac Dare Olulana
- Isadora Schwaab Guerini
- Israel Fernandez Pineda
- Ivan Bogdanovic
- Iyad Sultan
- Iyad Sultan
- J Benjamin
- J Hudson Barnett
- Jacqueline Elizabeth Montoya Vásquez
- Jake A Kloebe
- Jan Godzinsky
- Janice Hui Ling Wong
- Janita Zarrish
- Jasmin Meyer
- Jessica Luyt
- Jingdan Fan
- Joana Mafalda Monteiro
- John George Massoud
- John Mathew
- Joshua Erhabor
- José Andrés Molino
- Juan Luis García León
- Judith Lindbert
- Justina O Seyi-Olajide
- Kalu Ukoha
- Kamel Hamizi
- Kamrun Nahar
- Kareem O Musa
- Karl-Heinz Frosch
- Kashaf Turk
- Kate Cross
- Kazeem O O Ibrahim
- Kefas John Bwala
- Keffi Mubarak Musa
- Kellie McClafferty
- Kelvin Ifeanyichukwu Egbuchulem
- Kemal Tolga Saracoglu
- Ken Muma
- Kerri Becktell
- Kevin Crow
- Khadijah O Omokanye
- Khaled Abualkher
- Khalil Ghandour
- Khozairi Waleed
- Khushman Kaur Bhullar
- KingDavid Nweze
- Kingsley Appiah Bimpong
- Kingsley Aseye Hattor
- Kirk David Wyatt
- Kirstie Wright
- Kishwer Nadeem
- Kıvılcım Karadeniz Cerit
- Kokila Lakhoo
- Kokila Lakhoo
- Kokila Lakhoo
- Kokila Lakhoo
- Krithi Ravi
- Kwizera Festus
- Laila Hessissen
- Leanne Gentle
- Lennart Viezens
- Leon Köpke
- Licia Portela
- Lily Saldana
- Lorraine Ochieng
- Lubna Samad
- Lubna Samad
- Lucas Garschagen de Carvalho
- Lucas Krauel
- Lucien P Jay
- Lucy Davies
- Lukman O Abdur-Rahman
- Mabroukah Saeid Alshamikh
- Mahan Salehi
- Mahmoud Adly
- Mahmoud Ahmed Ebada
- Mahmoud Bassiony
- Mahmoud Elfiky
- Mahmoud M Saad
- Mahmoud Maher Abdelnaby Alrahawy
- Manasi Shirke
- Marc Dreimann
- Marco Aurelio Ciriaco Padilha
- Maria do Bom-Sucesso
- Maria Teresa Peña Gallardo
- Mariam Lami
- Marianne Monteiro Garrigo
- Maricarmen Olivos
- Marta de Andres Crespo
- Martin Stangenberg
- Martina Zambon
- Marwa Biala
- Marwa Shelft
- Mary Joan Kpiniong
- Maryam Ghavami Adel
- Maryam Khan
- Masooma Rana
- Matthew H V Byrne
- Matthew R Schuelke
- Matthias Priemel
- Max Pachl
- Max Pachl
- Max Pachl
- Mayara Caroline Amorim Fanelli
- Mayara Fanelli
- Md Afruzul Alam
- Md Asaduzzaman
- Md Asif Iqbal
- Md Hasanuzzaman
- Md Masud Rana
- Mebarki Malika
- Megan Murphy
- Mehdi Anouar Zekkour
- Mehdi Khan
- Mehdi Khan
- Mehnaz Akter
- Meryem Gounni
- Michael Boettcher
- Michael O Adegboye
- Mihailo Milicevic
- Mihir Sheth
- Milind Chitnis
- Milind Chitnis
- Mitchelle Obat
- Moawia Mohammed Ali Elhassan
- Mohamad K Abou Chaar
- Mohamad K Abou Chaar
- Mohamed Abdel-Maboud
- Mohamed Abdelwahab
- Mohamed Adwi
- Mohamed Ahmed
- Mohamed Bahaaeldin
- Mohamed Bella Jalloh
- Mohamed Bonna
- Mohamed El Kassas
- Mohamed Elbahnasawy
- Mohamed Gamal
- Mohamed Hassanin O'Sullivan
- Mohamed Mohamed Holail
- Mohamed Sherief
- Mohamed Yazid Kadir
- Mohamedraed Elshami
- Mohammad Ahmad
- Mohammad Ali Deeb
- Mohammad K Abou Chaar
- Mohammed A Azab
- Mohammed Miftah Faraj Almihashhish
- Mohammed Tanvir Ahammed
- Morgan Drucker
- Mostafa Qatora
- Muath Alser
- Muath Alser
- Muhammad Arshad
- Muhammad Arshad
- Muhammad Arshad
- Muhammad Rafie Raza
- Muhammad Rahil Khan
- Muhammed Elhadi
- Muhammed Elhadi
- Munawar Hraib
- Murad Almasri
- Muskaan Abdul Qadir
- Musliu Adetola Tolani
- Mustafa Sakar
- Mwangi Irungu
- N Otene ThankGod
- Nacer Khernane
- Nada Osman Yousif Elhaj
- Naema Khayyam
- Naif Al Bolowi
- Narjiss Aji
- Nathalie Galea
- Nathan Thompson
- Nazmul Islam
- Nehal Rahim
- Nellie Bell
- Nellie Patiala
- Nensi Melissa Ruzgar
- Nermin Badwi
- Nida Zia
- Nima Allafi
- Nisreen Ali
- Nitin James Peters
- Noel Peter
- Noel Peter
- Noel Peter
- Nsimire Mulanga Roseline
- Nyararai Togarepi
- Okechukwu Hyginus Ekwunife
- Okorie Ikechukwu
- Olagundoye Goke
- Olakayode Olaolu Ogundoyin
- Olanrewaju Moses
- Olayinka T Sayomi
- Olivia White
- Olubisi Olutosin Bamidele
- Olubunmi Motunrayo Fatungase
- Olubunmi Obafemi Obadaini
- Olufemi Oni
- Olumide Abiodun Elebute
- Oluseyi Oyebode Ogunsua
- Oluwasegun Joshua Afolaranmi
- Oluwaseun Ladipo-Ajayi
- Omaima El-Qurneh
- Omar Elmandouh
- Omar Hamam
- Orindom Shing Pulock
- Oudrhiri Mohammed Yassaad
- Outani Oumaima
- Pablo Velasco
- Paolo Musiu
- Paolo Sapienza
- Patricia Shinondo
- Patricia Shinondo
- Paul J Galardy
- Peter Gyamfi Kwarteng
- Philip Mari Mshelbwala
- Pierfrancesco Lapolla
- Pierfranco Cicerchia
- Pooja Kumari
- Poorvaprabha Patil
- Prasanna Gomes
- Priyansh Nathani
- R M Jeffri Ismail
- Rabbey Raza Khan
- Rachel Levinson
- Radovan Mijalcic
- Raja Mari Mohammed Nasef
- Ramsha Saleem
- Ranya M Baddourah
- Raphael N Vuille-Dit-Bille
- Raphael N Vuille-Dit-Bille
- Rasaq Olaosebikan
- Rawan Yasser Emam
- Reem Ghamgh
- Reem Mohamed Almowafy
- Reema Alnajjar
- Reto Baertschiger
- Reto M Baertschiger
- Reto M Baertschiger
- Rhea Raj
- Rhea Raj
- Ricardo Vianna de Carvalho
- Rim Elmandouh
- Rima Rahmoun
- Robert L Owen
- Robin Simpson
- Robyn Brown
- Rohan Pancharatnam
- Rohini Dutta
- Rohini Dutta
- Rohini Rajpal
- Rosanda Ilic
- Roshni Dasgupta
- Ruaa Bassam Ibrahim
- S M Rezanur Rahman
- Sabbir Karim
- Sadaf Altaf
- Sadia Muhammad
- Safia Lorabi
- Safia Lorabi
- Safia Lorabi
- Sai Pillarisetti
- Salah Eddine Oussama Kacimi
- Salma Naje Abu Teir
- Sameer Saleem Tebha
- Samson Olori
- Sana Tahir
- Sara Ali
- Sara Kader Alsaeiti
- Sarah Al-Furais
- Sarah Alfurais
- Sarah Muma
- Sarah Ullrich
- Sebastián Shu Yip
- Seham M Ragab
- Sergio López
- Sewar Elejla
- Shady Fadel
- Shahnoor Islam
- Shahnur Shah
- Shaima' Al-Dabaibeh
- Shakirullah AbdulAzeez
- Shashwat Kala
- Shatha Tailakh
- Shaun Wilson
- Sheba Mary Pognaa Kunfah
- Sherief Abdelsalam
- Sherief Ghozy
- Shireen Anne Nah
- Shireen Anne Nah
- Shweta Madhusudanan
- Shweta Madhusudanan
- Sima Ester Ferman
- Simona Meneghini
- Simone de Campos Vieira Abib
- Simone de Campos Vieira Abib
- Simone de Oliveira Coelho
- Simonede Campos Vieira Abib
- Smrithi Sriram
- Soha Zahid
- Soham Bandyopadhyay
- Soham Bandyopadhyay
- Soham Bandyopadhyay
- Somy Charuvila
- Sonal Nagras
- Sravani Royyuru
- Sreylis Nay
- Stacy Cooper
- Stefan G Holland-Cunz
- Stephanie Ajinkpang
- Suraj Gandhi
- Suraj Gandhi
- Susana Nunes
- Syeda Namayah Fatima Hussain
- Syukri Ahmad Zubaidi
- Tahmina Banu
- Tahmina Banu
- Taimur Iftikhar Qureshi
- Taiwo Akeem Lawal
- Taiwo Jones
- Tamara Elyan
- Tania Akter
- Tasmiah Tahera Aziz
- Thomas Smith
- Tijana Nastasovic
- Toqa Fahmawee
- Tufan Hicdonmez
- Tunde Talib Sholadoye
- Tybat Aliyu
- Tümay Umuroğlu
- Uduak Offiong
- Usama Eldaly
- Vaishnavi Govind
- Victor Calvagna
- Victor Calvagna
- Victor Khoury
- Vincent E Nwatah
- Vladimir Bascarevic
- Vuk Scepanovic
- Waha Rahama
- Wassem Shater
- William B Lo
- Yahya Elkaoune
- Yakubu Alfa
- Yara Hijazi
- Yasin Kara
- Yasir Al-Agele
- Yasmine El Chazli
- Yassine Zerizer
- Yousef Alalawi
- Youssef Sameh Badran
- Yuki Julius Ng
- Zain Douba
- Zannat Ara
- Zarina Abdul Latiff
- Zineb Bentounsi
- Zonaira Qayyum
- Publication venue
- 'BMJ'
- Publication date
- 01/01/2022
- Field of study
OBJECTIVES: Paediatric cancer is a leading cause of death for children. Children in low-income and middle-income countries (LMICs) were four times more likely to die than children in high-income countries (HICs). This study aimed to test the hypothesis that the COVID-19 pandemic had affected the delivery of healthcare services worldwide, and exacerbated the disparity in paediatric cancer outcomes between LMICs and HICs. DESIGN: A multicentre, international, collaborative cohort study. SETTING: 91 hospitals and cancer centres in 39 countries providing cancer treatment to paediatric patients between March and December 2020. PARTICIPANTS: Patients were included if they were under the age of 18 years, and newly diagnosed with or undergoing active cancer treatment for Acute lymphoblastic leukaemia, non-Hodgkin's lymphoma, Hodgkin lymphoma, Wilms' tumour, sarcoma, retinoblastoma, gliomas, medulloblastomas or neuroblastomas, in keeping with the WHO Global Initiative for Childhood Cancer. MAIN OUTCOME MEASURE: All-cause mortality at 30 days and 90 days. RESULTS: 1660 patients were recruited. 219 children had changes to their treatment due to the pandemic. Patients in LMICs were primarily affected (n=182/219, 83.1%). Relative to patients with paediatric cancer in HICs, patients with paediatric cancer in LMICs had 12.1 (95% CI 2.93 to 50.3) and 7.9 (95% CI 3.2 to 19.7) times the odds of death at 30 days and 90 days, respectively, after presentation during the COVID-19 pandemic (p<0.001). After adjusting for confounders, patients with paediatric cancer in LMICs had 15.6 (95% CI 3.7 to 65.8) times the odds of death at 30 days (p<0.001). CONCLUSIONS: The COVID-19 pandemic has affected paediatric oncology service provision. It has disproportionately affected patients in LMICs, highlighting and compounding existing disparities in healthcare systems globally that need addressing urgently. However, many patients with paediatric cancer continued to receive their normal standard of care. This speaks to the adaptability and resilience of healthcare systems and healthcare workers globally
Geoeconomic variations in epidemiology, ventilation management, and outcomes in invasively ventilated intensive care unit patients without acute respiratory distress syndrome: a pooled analysis of four observational studies
- Author
- Aage Christiansen
- Aaradhana Adhikari
- Aaron Venti
- Aayesha Qadeer
- Abdellatif Benslama
- Abigail Beane
- Abu Hena Mostafa Kamal
- Abul Faiz
- Adam B Schlichting
- Adam Bell Bell
- Adenilton M R Ampinelli
- Aditya Uppalapati
- Adrian Donnelly
- Adriana M Fernandez
- Adrien Robine
- Aftab Akhtar
- Agreta Gecaj-Gashi
- Ahmed Farooq
- Ahmed S Al Jabbary
- Ahmet Dilek
- Ahmet Sukru Denker
- Ai Y Hang
- Aiman Tulaimat
- Akihiro Takaba
- Akinori Uchiyama
- Akira Hirata
- Akm Shamsul Alam
- Akut Aytulun
- Alain Combes
- Alain M Dive
- Alain Mercat
- Alain U Alisasis
- Alan Zazu
- Alastair Rose
- Alberto Deicas
- Alec A Tallet Alfonso
- Alejandro A Saez
- Alejandro Ebeid
- Alejandro G Castro
- Alejandro R Bruhn
- Alek Kumar
- Alessandro Bacuzzi
- Alessandro Protti
- Alessia Mattei
- Alex Mcleod
- Alex Morton
- Alexandra Ceniceros-Barros
- Alexandra J Williams
- Alexandra Marcu
- Alexandra Siqueira Colombo
- Alexandre Biasi Cavalcanti
- Alexandre Biasi Cavalcanti
- Alexandre Chan
- Alexandre Demoule
- Alexandre Guilherme Ribeiro de Carvalho
- Alexandre Molin
- Alexandre Molin
- Alexey I Gritsan
- Alfons Arizmendi
- Aline Ascoli
- Alison Ghosh
- Alistair Nichol
- Alistair Roy Roy
- Alma Cani
- Alvaro Ramirez-Gutierrez
- Amadeu Martinez
- Amanda Cowton
- Amanda Krstevski
- Amanda Maria R R de Oliveira
- Amanda Skinner
- Amanda Whileman
- Amine Ali Zeggwagh
- Amine Ali Zeggwagh
- Amy McInerney
- Ana Carolina P Antônio
- Ana Carolina Peçanha
- Ana G França
- Ana M Araujo
- Ana M Pellicer
- Anais Briquet
- Anand Dongre
- Anatole Harrois
- Anders Aneman
- Anders Larsson
- Andre Japiassu
- Andre Luiz Baptiston Nunes
- Andre Luiz Baptiston Nunes
- Andre Vercueil
- Andrea Coppadoro
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Lombardo
- Andrea N Cracchiolo
- Andrea Tinnirello
- Andreas Barratt-Due
- Andreas W Reske
- Andrej Sribar
- Andrew Bentley
- Andrew Corner
- Andrew Ferguson
- Andrew J Burtenshaw
- Andrey A Gazenkampf
- André Peretti Torelly
- Angela Delsing
- Angela Pinder
- Aniko D Frigyik
- Anil Hormis
- Anil P Hormis
- Anitha Shenoy
- Anna Hunt
- Anna Oscarsson Tibblin
- Anna Rossi
- Anna T Dowling
- Anna Walker
- Anna-Karin Morin
- Anne Adolfsson
- Anne B Guttormsen
- Annop Piriyapatsom
- Antero do Vale Fernandes
- Antoine Pronovost
- Antonino Giarratano
- Antonio Artigas
- Antonio Braschi
- Antonio Carlos Nogueira
- Antonio G Jimenez
- Antonio Jorge Pereira
- Antonio L Ruiz-Aguilar
- Antonio P Nassar Jr
- Antonio Paulo Nassar Junior
- António M Alvarez
- António M Messias
- Aogan C O'Muircheartaigh
- Areef Ahsan
- Areej Javeed
- Ariel Chena
- Arnaud Follin
- Arshad Taqi
- Arvind K Baronia
- Ary Serpa Neto
- Ashley Schomer
- Ashok S Raj
- Asisclo J Villagomez
- Asisclo Villagomez
- Asma Ben Souissi
- Asma Navasakulpong
- Asoka Gunaratne
- Atta Ur Rehman
- Aurelia M Martinho
- Aylin Seven
- Bao H Zhu
- Barbara Brunettini
- Barbara do Cs Martins
- Barrett T Kitch
- Barry Dixon
- Barry Kennedy
- Basak Ceyda Meco
- Batoul Khoundabi
- Beatriz C Tan
- Behzad Nadjm
- Ben Creagh-Brown
- Bernard Goubaux
- Bernhard Holzgraefe
- Bhagyesh Shah
- Bhuvana Krishna
- Bimal Kudavidanage
- Bin Li
- Bingyu Qin
- Bojan Jovanovic
- Boris G Villamagua
- Brenno Cardoso Gomes
- Brigit L Roberts
- Brit Å Sjøbø
- Bruno Franco Mazza
- Bruno Gelée
- Bruno S Oliveira
- Candelaria De Haro
- Carlo A Volta
- Carlo Alberto Volta
- Carlos A Pellegrini
- Carlos Eduardo Barboza
- Carlos Munhoz
- Carlos S Pereira
- Carly Brown
- Carmen Scott
- Carolina Quintana Grijalba
- Carolina S Insaurralde
- Carolina Serra
- Caroline Berghe
- Caroline C MacFie
- Caroline Wreybrown
- Cassia Righy
- Cassiano Teixeira
- Catalina Forteza
- Catherine Plowright
- Cecilia Carbayo-Gorriz
- Cecilia Hermosa
- Ceri E Battle
- Cesar A Cortez
- Cesar Milstein
- Cesar P Pere
- Chamila Pilimatalawwe
- Charlene Bigot
- Charlene Le Moal
- Charlotte Downes
- Chathurani Sigera
- Chern Min Voon
- Cheryl Padilla-Harris
- Chinni Krishna Kasi
- Chloe Hughes
- Christian C Rylander
- Christian Dellera
- Christian Frey
- Christian M Ramirez-Alfaro
- Christian Schlegel
- Christina Whitehead
- Christine Boyd
- Christine Brown
- Christine Ryan
- Christoph Muench
- Christopher J Scott
- Christopher Nutt
- Christopher Smalley
- Christopher Tainter
- Chunting Wang
- Claine Judy
- Clair Harris
- Claire Kaloo
- Claire Matthews
- Claire Miller
- Claire Pegg
- Claire Reynolds
- Clare Bullock
- Clare Mellis
- Clare Mellis
- Claude Guérin
- Claudia A Ortiz
- Claudia R Estrella
- Claudio H Gonçalves
- Claudio Piras
- Claudio Piras
- Claudio Piras
- Colette Seasman
- Colette Seasman
- Colin K Grissom
- Colin Mcarthur
- Colin S Black
- Cora Lavigne Moreira
- Corcoles G Virgilio
- Corinne Leemann-Refondini
- Cristiane Ritter
- Cristiane Tomasi Damiani
- Cristina M Cox
- Cristina Prata Amendola
- Cristina Santos
- Cristina Santos
- Cédric Daubin
- Daisuke Niimi
- Dale J Yeatts
- Dalton de Souza Barros
- Damien Roux
- Dan E Corneci
- Dan Hadfield
- Dana R Tomescu
- Daniel Aragão
- Daniel Beraldo
- Daniel Collins
- Daniel da Cunha Ribeiro
- Daniel F McAuley
- Daniel Hadfield
- Daniel Hull
- Daniel O Beraldo
- Daniel Prado
- Daniel R Crouch
- Daniel R Gonzalez
- Daniel V Collins
- Daniela Albiero
- Daniela M Palma
- Daniela N Vasquez
- Daniele M Combaux
- Danielle A Fawkes
- Danielle C Fontenele
- Danielle J Hacking
- Danielle Nobrega
- Danielle Reuter
- Danny McAuley
- Dany Goldgran-Toledano
- Dat Vu Quoc
- Davi Cristovao
- David D Llinares Moya
- David Pogson
- David Rogerson
- David Shaw
- David W Wrathall
- Davide D'Antini
- Dawn Trodd
- Debabrata Banik
- Debbie Weller
- Deborah M Inskip
- Deborah Smith
- Deborah Wilson
- Deeban Ganesan
- Demet Aydin
- Denis Doyen
- Denise Donaldson
- Denise Griffin
- Dharshinie Dorasamy
- Diego Pastor Marcos
- Dimitrios Matamis
- Dina Gomaa
- Dina Gomaa
- Dina Ismail
- Dk Maizatul Aiman B Pg Hj Ismail
- Donald A Irvine
- Donall O'Croinin
- Donatella Mestria
- Dora Mannarino
- Dorel Sandesc
- Dorothy M Breen
- Dorothée Carpentier
- Dulce M Dector
- Dyanne Moysés Dalcomune
- Dácil Parrilla Toribio
- Ed Bajwa
- Eddy Fan
- Edel A Meaney
- Edgardo E Tabhan
- Edgardo Nuñez
- Edgardo Tabhan
- Edison Moraes
- Eduardo Beck
- Eduardo Di Lauro
- Eduardo F Labarca
- Eimhin S Dunne
- Eizo Watanabe
- Elaine Ferreira
- Eldar Søreide
- Electra E Stamou
- Elena Frati
- Elena Gallego Curto
- Elena Perez Losada
- Eleni K Mouloudi
- Eleni V Massa
- Eliana Bernadete Caser
- Eliane Bernadete Caser
- Elie H Zogheib
- Eliezer Silva
- Elisa Estenssoro
- Elisa Seghelini
- Elisabetta Pecci
- Elise P Sauvadet
- Ellada V Kiourtzieva
- Elton Afonso Lopes
- Emanuel Cirstea
- Emilio M Osman
- Emma L Willett
- Emre Erbabacan
- Enrique A Piacentini
- Enrique Cereijo
- Eoin Young
- Erika E Borotto
- Erin Nishikawa
- Erna Alberts
- Esther Bermejo Lopez
- Esther Diaz-Rodriguez
- Ettore R Vascotto
- Eva O Nagy
- Evangelos Kalaitzis
- Evelin Drociunas Pacheco
- Evgeny Grigoriev
- Evren Senturk
- Ewan C Goligher
- Fa C Zhou
- Fabien Grelon
- Fabienne D Simonis
- Fabienne D Simonis
- Fabio Tarantino
- Fabrice Daviaud
- Fahd Amir
- Fan Zhang
- Farah Idrees
- Farooq Brohi
- Farshad Heidari
- Fatma Ulger
- Fayez M Kheir
- Feda Kahveci
- Federico Gordo
- Fekri Abroug
- Felipe A Aliaga
- Felipe Dal-Pizzol
- Felipe Saddy
- Felipe T Martinez
- Ferdinando Raimondi
- Fernanda Eugênia Fernandes
- Fernando Borges Rodriguez
- Fernando G George
- Fernando José da Silva Ramos
- Fernando Rios
- Ferran Roche-Campo
- Filipa M Barros
- Finn H Andersen
- Flavia A Loiacono
- Flavia Ribeiro Machado
- Francesco L Santoli
- Francesco Mojoli
- Francesco Raponi
- Francis Schneider
- Francisca G Cazorla-Barranquero
- Francisco Esteve
- Francisco Javier Flores Mejia
- Francisco P Huerta
- Francisco Soriano
- Francois Beloncle
- Frank Stansil
- Frank Van Haren
- Frank Van Haren
- Frantz Berkelmans
- Frederico Bruzzi Carvalho
- Fredrik Schiöler
- Fredy A Montes Oscanoa
- Fredy S Lora
- Fumihito Ito
- Fábio Poianas Giannini
- Gabriel Démpaire
- Gabriele Sales
- Gabrielle C Hanlon
- Gaetan Béduneau
- Galen Henderson
- Garcia M Elisabet
- Gareth P Sellors
- Gary H Mills
- Gautier Buzancais
- Gayle Clifford
- Ged Dempsey
- Gemma Rialp
- Gerard Curley
- Ghaleb Almekhlafi
- Ghanem M Mustafa
- Ghassan Kamel
- Giacomo Bellani
- Giacomo Monti
- Gianluca Zani
- Giannis A Zacharas
- Gilda Cinnella
- Giorgio A Iotti
- Giovana Colozza Mecatti
- Giovanna Occhipinti
- Giovanna Panarello
- Giulia Crapelli
- Giuseppe Foti
- Giuseppe Melchionda
- Gonzalo Navarro
- Greet Hermans
- Guilherme Schettino
- Guillaume Barberet
- Guillaume Carteaux
- Guillermo Bugedo
- Guillermo M Albaiceta
- Gulay Eren
- Gustavo A Plotnikow
- Gustavo Affonso de Oliveira
- Gustavo M Montanha
- Gustavo Pittini
- Guy M Francois
- Gyan Kayashta
- Gyorgy Frendl
- Güldem Turan
- Ha Nguyen Thi Thanh
- Haibo Qiu
- Haibo Qiu
- Haitao Liu
- Hamidreza Jamaati
- Hanane Ezzouine
- Hannah Crowther
- Hans Kedelv
- Hans-Bernd F Hopf
- Hasan M Al Dorzi
- Hazel Spencer
- Heather Blaylock
- Hector H Leon Yoshido
- Heera L Mahto
- Heidi Dawson
- Hektor Sula
- Helen E Ellis
- Helen Green Green
- Helen J Rodgers
- Helen Robertson
- Helen Rodgers
- Helen S Wong
- Helen Talbot
- Helen Wong
- Helena Barcraft-Barnes
- Helga Ceunen
- Helga Ceunen
- Hellen M Van Wezel
- Henrik Appelberg
- Henrik Reschreiter
- Henrik Reschreiter
- Hermann Wrigge
- Hermann Wrigge
- Hernan Aguirre-Bermeo
- Hernan Gianinetto
- Herve Dupont
- Herve Lebbinck
- Hervé O Zender
- Hicham Balkhi
- Hiroki N Maeyama
- Hiroshi Imai
- Hiroyasu Kimura
- Hiroyuki Honda
- Hiroyuki Suzuki
- Hiroyuki Tanaka
- Hitesh Batra
- Hua X Wang
- Huanzhang Shao
- Hui Han
- Huiying Zhao
- Hulya Ulusoy
- Huseyin Toman
- Hélder Konrad de Melo
- Iain McCullagh
- Ian White
- Ichiko Mizuguchi
- Ilaria Pattarino
- Ilkay Ceylan
- Imed Chouchene
- Imo Aisiku
- Ingeborg D Welters
- Ingeborg Welters
- Ingela Nygren
- Ingrid van den Hul
- Iqbal Memon
- Irene M Bailey
- Isabel M Serra
- Isabela Ambrósio Gava
- Isabelle Reed
- Isil Kose
- Islem Ouanes
- Israel Maia
- Istvan Kajtor
- Jack R Richecoeur
- Jack Steinberg
- Jacob S Yumha
- Jacques Duranteau
- Jade M Cole
- Jaime E Solis-Quesada
- Jakob Gjedsted
- James Limb
- Jan Máca
- Jan Máca
- Janaki Arumoli
- Jane Adderly
- Jane Hunt
- Jane Martin
- Jane Montgomery
- Jane Snell
- Janet S Aguirre
- Jarone Lee
- Jason E Cohen
- Javier Alvarez
- Javier Blanco
- Javier E Salas
- Javier G Alonso
- Javier Hurtado
- Javier Hurtado
- Javier Hurtado
- Jean Dellamonica
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- Tai Pham
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- Taohidul Majid Taohid
- Tarek Dendane
- Tarikul Hamid
- Tasmin Patel
- Tatjana Simurina
- Teresa Honrubia
- Terri-Ann Sewell
- Tharwat M Aisa
- Theonymfi G Papavasilopoulou
- Thiago Lisboa
- Thomas Baltus
- Thomas C Blakeman
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- Thomas Kander
- Thomas Staudinger
- Thuy Duong Bich
- Théia Forny Wanderley Castellões
- Tiago Macruz
- Tie H Qin
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- Tom Hatton
- Tomas P Roser
- Tomaz Mesar
- Tomaz Mesar
- Tommaso Fossali
- Tomoaki Hashida
- Tomofumi Harasawa
- Tomoyuki Nakamura
- Toni E Mckenna
- Toshikazu Abe
- Tracey Evans
- Trevor W Oetting
- Troy S B Rowne
- Tài Pham
- Udomsak Silachamroon
- Ugur Goktas
- Ulysses V A Silva
- Una Poultney
- Unase Buyukkocak
- Upeka Samaranayake
- Ushio Higashijima
- Valeria I Cerrato
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- Vanessa Linnett
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- Varsha Kadaba
- Vasilis Ourailogloy
- Venika Manoharan
- Venkatapura J Ramesh
- Veronica Villar
- Vesna Bumbasierevic
- Vesna Bumbasirevic
- Vicente Cés de Souza Dantas
- Vijayanand Palaniswamy
- Vincenzo Pota
- Vincenzo Russotto
- Vincenzo Schiavone
- Viratch Tangsujaritvijit
- Virginie Lemiale
- Visanthi Pinto
- Vivek Kakar
- Vladimir Cerny
- Vlasta Klaric
- Wahid Altaf
- Wajdi Maazouzi
- Wei H Zhu
- Wei Wang
- Weihua Lu
- Wenkui Yu
- Wenwen Li
- Werner Schmid
- William Stigler
- Xavier Wittebole
- Xian Y Zhao
- Xiao B Huang
- Xiao L Li
- Xiaoming Luo
- Xing Y Zhang
- Xinyu Li
- Y A Hasitha Dilhani
- Ya Q Wu
- Yaasen Arabi
- Yan Gao
- Yaseen M Arabi
- Yasuaki Ogino
- Yavuz Orak
- Yen Lam Minh
- Yi Han
- Yimin Li
- Yonghao Xu
- Yoshihiro Yamaji
- Yoshinobu Kameyama
- Youssef Haddad
- Youzhong An
- Yozo Kashiwa
- Yu D Di
- Yuan N Gao
- Yuan Y Li
- Yuanhua Lu
- Yves D Jarquin-Badiola
- Zerrin Demirtürk
- Zhe Zhai
- Zheng L Ye
- Zhenyang He
- Zhou Li-Xin
- Álvaro Réa-Neto
- Ángela Algaba
- Ángela González-Salamanca
- Çiler Zincircioglu
- Érica Aranha Suzumura
- Ênio Rego
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Background: Geoeconomic variations in epidemiology, the practice of ventilation, and outcome in invasively ventilated intensive care unit (ICU) patients without acute respiratory distress syndrome (ARDS) remain unexplored. In this analysis we aim to address these gaps using individual patient data of four large observational studies.
Methods: In this pooled analysis we harmonised individual patient data from the ERICC, LUNG SAFE, PRoVENT, and PRoVENT-iMiC prospective observational studies, which were conducted from June, 2011, to December, 2018, in 534 ICUs in 54 countries. We used the 2016 World Bank classification to define two geoeconomic regions: middle-income countries (MICs) and high-income countries (HICs). ARDS was defined according to the Berlin criteria. Descriptive statistics were used to compare patients in MICs versus HICs. The primary outcome was the use of low tidal volume ventilation (LTVV) for the first 3 days of mechanical ventilation. Secondary outcomes were key ventilation parameters (tidal volume size, positive end-expiratory pressure, fraction of inspired oxygen, peak pressure, plateau pressure, driving pressure, and respiratory rate), patient characteristics, the risk for and actual development of acute respiratory distress syndrome after the first day of ventilation, duration of ventilation, ICU length of stay, and ICU mortality.
Findings: Of the 7608 patients included in the original studies, this analysis included 3852 patients without ARDS, of whom 2345 were from MICs and 1507 were from HICs. Patients in MICs were younger, shorter and with a slightly lower body-mass index, more often had diabetes and active cancer, but less often chronic obstructive pulmonary disease and heart failure than patients from HICs. Sequential organ failure assessment scores were similar in MICs and HICs. Use of LTVV in MICs and HICs was comparable (42·4% vs 44·2%; absolute difference -1·69 [-9·58 to 6·11] p=0·67; data available in 3174 [82%] of 3852 patients). The median applied positive end expiratory pressure was lower in MICs than in HICs (5 [IQR 5-8] vs 6 [5-8] cm H2O; p=0·0011). ICU mortality was higher in MICs than in HICs (30·5% vs 19·9%; p=0·0004; adjusted effect 16·41% [95% CI 9·52-23·52]; p<0·0001) and was inversely associated with gross domestic product (adjusted odds ratio for a US$10 000 increase per capita 0·80 [95% CI 0·75-0·86]; p<0·0001).
Interpretation: Despite similar disease severity and ventilation management, ICU mortality in patients without ARDS is higher in MICs than in HICs, with a strong association with country-level economic status
Global economic burden of unmet surgical need for appendicitis
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Mohamed
- Abbasy Jibran
- Abbo Olivier
- Abbouch Meryem
- Abd-Elmawla Manar
- Abd-Elrasoul Yasmin
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdel-Wahab Nehal Yosri Elsayed
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- AbdelFattah Ibrahim
- Abdelgelil Asmaa
- Abdelghany Sarah
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkareem Ahmed
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraheim Mohamed
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshafy Mahmoud
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulbagi Omar
- Abdulgawad Mahmoud
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abebe Nebiyou Seyoum
- Abebe Nebyou Seyoum
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboarab Aya
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R.
- Aboraya Metwally
- Aboraya Mohammad
- Abouelnasr Alaa
- Aboul-Naga Mariam Saad
- Abouzahra Amany
- Abouzaid Arwa
- Abozaid Mohamed
- Abozeid Khaled
- Abozyed Mahmoud Ahmed Fathi
- Abu-toyour Maram
- Abubakr Marwan
- Abudeeb Haytham
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abuseif Mohamed
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Nourhan
- Adams Ryan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adekoya Adeleke
- Adel Abdalrahman
- Adel Ahmed
- Adel Badr Eldin
- Adel Israa
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- null null
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- Salas Marilia Del Carmen Escalante
- Salcedo Jannin
- Sale Danjuma
- Saleh Amr Ahmed
- Saleh Omar
- Salem Hosni Khairy
- Salem Menatalla
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- Sallam Abd Elkhalek
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- Salma Mahmoud
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- Salman Ayman
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- Samalavicius Narimantas E.
- Samaniego Camila Sanchez
- Samaraweera Dulan Irusha
- Samih Hisham
- Samir Ahmed
- Samison Luc Hervé
- Sammarco Giuseppe
- Sammut Keith
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- Samson Garba
- Samuel Sani Ali
- Samy Mostada
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- Sanad Aly
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- Saravia Fridiz
- Sarmah Panchali
- Sarsik Sameh
- Sarwary Sayed
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- Sauvat Frederique
- Saverio Salomone Di
- Saw Jian Er
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- Sayed Gehad Samir El
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- Scalabre Aurelien
- Schadde Erik
- Schiavone Roberto
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- Schoewe Christin
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- Scicluna Ruth
- Segundo Luiz Carlos Barros De Castro
- Seif Mostafa
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- Seisay Sam
- Selvaggi Francesco
- Selvaggi Lucio
- Semeda Nourhan
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- Servin Gustavo Rodolfo Pertersen
- Setiawan Jonny
- Seto Djifid Morel
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- Sfougaris Dimitrios
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- Shaalan Mohamed
- Shabkah Alaa
- Shachykava Tatsiana
- Shah Apar
- Shah Jamie
- Shah Rohi
- Shaharuddin Shahadatul
- Shaheen Alaa
- Shahine Ahmed
- Shahzad Noman
- Shaikh Nihaal
- Shaker Heba
- Shaker Ramadan
- Shaker Ramdan
- Shakshouk Hend Adel Gawad
- Shalabi Ahmad
- Shalaby Mahmoud
- Shalaby Mostafa
- Shamasneh Ala
- Shamsedine Ahmed W.
- Shamsi Ghina Shamim
- Sharpin Claire
- Shatkar Veereanna
- Shaw Catherine A
- Shawki Marwan
- Shawky Martina Yusuf
- Shawqi Muhammad
- Sheehan Jacqueline
- Shehata Sherif
- Sherman Thomas
- Sheshe Abdulrahman
- Sheshe Abdurrahaman
- Sheta Ahmed
- Shimy Gamal
- Shiwani Haaris A.
- Shiwani Hunain
- Sholadoye Tunde
- Shoura Yousra El
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- Siguantay Miguel
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- Sila George Manrique
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- Silvestri Vania
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- Slapelyte Evelina
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- Sleem Mohamed
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- Snyder Elizabeth
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- Soeselo Daniel Ardian
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- Soliman Ahmed
- Soliman Ahmed Ragab
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- Souaibou Yacoubou Imorou
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- Spence Richard
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- Sruogiene Elena Zdanyte
- Staerkle Ralph F
- Starr Nichole
- Steccanella Francesca
- Stefanopoulos Anastasios
- Stock Simon
- Stoddart Michael
- Straten Stephanie Van
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- Strupas Kestutis
- Stuva Jessica Patricia Gonzales
- Styles Kristian
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- Subocius Andrejus
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- Sundstrom Sami Martin
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- Swann Joanna
- Syibrah Khuzaimah Zahid
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- Szeto Kylie Joan-yi
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- Søreide Kjetil
- Tabiri Stephen
- Tackie Enoch
- Taddei Antonio
- Tade Adesoji
- Taha Emad Mohamed Saeed
- Tahboub Haya
- Taher Ayman And
- Taher Mustafa Mohammed
- Taieb Chouikh
- Taiwo Agboola
- Taiwo Ogechukwu
- Talaat Muhammed
- Tale Fernando
- Tale Luis
- Talukder Shagorika
- Talving Peep
- Tammam Ahmed
- Tan Choy Ling
- Tan Jessica Juliana
- Tan Joel Kin
- Tan Keith Say Kwang
- Tan Ryan Choon Kiat
- Tan Yee Wen
- Tan Yi Koon
- Tanase Andrei
- Tarek Adham
- Tarek Areej
- Tarek Dina
- Targa Simone
- Tariq Sherif
- Tata Mahadevan Deva
- Tatagiba Luiza Sarmento
- Tawfik Badreldin Adel
- Tawfik Gehad
- Teasdale Ella
- Tedeschi Umberto
- Tedjaatmadja Chintya
- Telfah Muwaffaq Mezeil
- Tembo Thelma
- Temoche Edilberto
- Teo Shuang Yi
- Tessera Gaetano
- Teufelberger Gerfried
- Tew Yong Yong
- Tewari Shirish
- Thabet Waleed
- Thanusan Vimalakanthan
- Tharmalingam Shivanee
- Theodosopoulos Theodosios
- Thollot Aurore
- Thomas Efeson
- Thomas Hannah S
- Thompson Ben
- Thorarinsdottir Hildur
- Thorell Anders
- Thorsen Kenneth
- Ticona Willy Alcca
- Timothy Oyediran Kehinde
- Ting Jesse Ron Swire
- Toeema Aliaa Gamal
- Toit Frederick Du
- Tolba Hager
- Tolg Cecilia
- Tolonen Matti
- Tolotra Todisoa Emmanuella Christina
- Tori Sayeeda Aktar
- Torres Carla Pierina García
- Torres Shalon Guevara
- Trompetto Mario
- Tselos Angelos
- Tshisola Serge Kapenda
- Tugnoli Gregorio
- Tun Aung Kyaw
- Tun Myint
- Turati Luca
- Turkustani Sondos
- Turner Megan
- Tutino Roberta
- Tverskis Zygimantas
- Tyler Robert
- Tze R. Goh Ern
- Tze Reuben Goh Ern
- Tzikos Georgios
- Ubiali Paolo
- Ugalde Paul
- Ukwenya Yahaya
- Uluşahin Mehmet
- Upadhyaya Vijaid
- Upchurch Emma
- Urbanavicius Linas
- Urniežius Zigmantas
- Urquizu Mario Contreras
- Usaityte Ausrine
- Uščinas Laimonas
- Utter Maria
- Uzabumwana Norbert
- Vaicius Arturas
- Valcarcel-Saldaña María
- Valioulis Ioannis
- Vargas Marvin
- Varkalys Karolis
- Vartic Mihaela
- Vasquez Giorgio
- Vasquez Idelso
- Veen Torhild
- Vega Gustavo Miguel Machain
- Velasquez Ricardo
- Velásquez Armando José Román
- Velásquez Carlos Iván Pérez
- Vella-Baldacchino Martinique
- Venclauskas Linas
- Vendramin Elena
- Venskutonis Donatas
- Venugopal Caranj
- Verjee Azmina
- Vermaas Maarten
- Veronese Ezio
- Vianna Julia Guasti Pinto
- Vicario Erika
- Vida Lucian Corneliu
- Vilčinskas Mantas
- Villa Roberta
- Villalobos Santiago
- Vimalachandran Dale
- Vincent Joe
- Violi Paola
- Višinskas Petras
- Vivekanantham Sayinthen
- Vlachogiorgos Apostolos
- Vollmer Sebastian
- Voulgaris Evangelos
- Wael Noha
- Wagener Mark
- Waleed Hamza
- Walędziak Maciej
- Walsh Michael
- Waqar Muhammad
- Warda Mahmoud
- Warren Oliver
- Waterman Ade
- Watts Anna
- Weber Beatrix
- Weber Per
- Weiser Thomas G
- Wheeler James
- Whitaker John
- White Timothy
- Whitehurst Katharine
- Wiborg Joachim
- Widiastini T Ariani
- Wild Jonathan R L
- Williams Omolara
- Wilson Ling
- Wilson Michael
- Witherspoon Paul
- Wogensen Fredrik
- Woin Evelina
- Wold Trude Beate
- Wolf Bernhard
- Wondimu Sahlu
- Wondoh Paul
- Wong Chee Siong
- Wong Chui Yee
- Wong Hong Yee
- Wood Greta
- Woodward Helen
- Worku Mengistu
- Worku Tewodros
- Wredberg Cecilia
- Wright Naomi J
- Xerri Thelma
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yaseen Tahir
- Yaseen Tahir Muhammad
- Yavuz Mehmet Ali
- Ye Joselyn
- Yeang Li Jing
- Yeo Lee Shi
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yip Chingwan
- Yip Sebastian Bernardo Shu
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yong Cheryl Ou
- Yong Guo Liang
- Youssef Daniel
- Youssef Haney
- Youssef Mohamed
- Youssif Jehad Hassan
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zachariades Dimitris-Christos
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zalabia Mohamed F
- Zamarin Kresimir
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zardab Ali
- Zegarra Sergio
- Zerihun Abebe Bekele
- Zhang Zhongtao
- Zheng Fei
- Zidan Hagar
- Zidan Mohamed
- Ziff Oliver
- Zil-E-Ali Ahsan
- Zohair Ahmed
- Zuber Markus
- Zulkifli Athirah
- Žilinskas Justas
- Žilinskienė Reda
- Žiubrytė Greta
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2022
- Field of study
Background There is a substantial gap in provision of adequate surgical care in many low- and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
Global economic burden of unmet surgical need for appendicitis
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Mohamed
- Abbasy Jibran
- Abbo Olivier
- Abbouch Meryem
- Abd-Elmawla Manar
- Abd-Elrasoul Yasmin
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdel-Wahab Nehal Yosri Elsayed
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- AbdelFattah Ibrahim
- Abdelgelil Asmaa
- Abdelghany Sarah
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkareem Ahmed
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraheim Mohamed
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshafy Mahmoud
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulbagi Omar
- Abdulgawad Mahmoud
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abebe Nebiyou Seyoum
- Abebe Nebyou Seyoum
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboarab Aya
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R.
- Aboraya Metwally
- Aboraya Mohammad
- Abouelnasr Alaa
- Aboul-Naga Mariam Saad
- Abouzahra Amany
- Abouzaid Arwa
- Abozaid Mohamed
- Abozeid Khaled
- Abozyed Mahmoud Ahmed Fathi
- Abu-toyour Maram
- Abubakr Marwan
- Abudeeb Haytham
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abuseif Mohamed
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Nourhan
- Adams Ryan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adekoya Adeleke
- Adel Abdalrahman
- Adel Ahmed
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji O
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesuyi Abidemi
- Adeyeye Ademola
- Adham Walid
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O
- Adnan Ahmad Bin
- Adu-Aryee Niiarmah
- Afana Samah
- Afandy Ahmed
- Afifi Ahmed Mohamed
- Africa South
- Agalianos Christos
- Agarwal Arnav
- Agbedinu Kwabena
- Agius Marija
- Aglan Amro
- Aguilar Wendy Leslie Messa
- Aguilar-Jimenez Jose
- Aguilera Maria Lorena
- Aguilera Omar
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahmed Ahmed
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Emad Ali
- Ahmed Hala
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahmed Soliman Magdy
- Ahounou Ernest Yemalin Stephane
- Aigrain Yves
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi E
- Ajiboye Anthony
- Akatibo Emmanuel
- Akeel Nouf
- Akoto Elliot
- Al-Aarag Asmaa Abdel-Rahman
- Al-Azraqi Israa Abdullah Aziz
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-Faifi Jubran J
- Al-faqawi Maha
- Al-farram Hadeel
- Al-Hameedi Hasan Ismael Ibraheem
- Al-Hasani Ruqaya Kadhim Mohammed Jawad
- Al-khatib Ahmed
- Al-Mallah Abdullah
- Al-Marakby Dina
- Al-Mousa Mashael
- Al-Nahrawi Safwat
- Al-Obaedi Ossama
- Al-saqqa Sara
- Al-Saqqa Sara W
- Al-shammari Abeer
- Al-Slaibi Ibrahim
- Al-taher Taher
- Alada Muslimat
- Alahmady Omar
- Alakaloko Felix
- Alaloul Enas
- Alamin Shadid
- Alamoudi Mohammed
- Alamoudi Uthman
- Albeladi Bandar
- Albiety Adel
- Aldalaq Ahmad
- Aldhafeeri Salman
- Aledrisy Mohannad
- Alexander Philip
- Alexandre Challine
- Alfarsi Muayad Ahmed
- Alghamdi Ahmed
- Alghamdi Basim
- Alghamdi Masood
- Alghamdi Mohammed Saleh A.
- Algohary Osama
- Alhabli Ibrahim
- Alhady Khaled
- Alhassan Basmah
- Alhazmi Wedyan
- Alhendy Mohammed
- Alherz Mohammad
- Ali Ahmad
- Ali Ahmed
- Ali Ased
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Farah Mahmoud
- Ali Hussein
- Ali Safia
- Ali Samuel Sani
- Ali Syed Abdul Wahhab Eusoffee Wan
- Ali Tebian Hassanein Ahmed
- Alihonou Thierry
- Alimi Quentin
- Aliyu Halima
- Aliyu Mohammad
- Aliyu Shamsudeen
- Aljboor Khaled
- Aljiffry Murad
- Aljohani Emad
- Aljohani Saud
- Alkaaki Aroub
- Alkammash Abdelrahman
- Alkelani Muhammad
- Alkhabbaz Dalia
- Allam Meran
- Allam Mostafa
- Allam Yomna
- Allegri Andrea
- Allen John Lee Y
- Almallah Ahmad
- Almanon Christel Leanne
- Almoflihi Abdullah
- Almuallem Sultan
- Almy Jack
- Alnaby Mohamed Hassab
- Alnawam Ehab
- Alnuqaydan Saleh A.
- Alnusairat Aseel
- Alomar Ibrahim N.
- Alqahtani Enas
- Alqahtani Saleh
- Alrahawy Mahmoud
- Alrajraji Mawaddah
- Alrifaie Ahmad
- AlRowais Mohammed
- Alsaggaf Mohammed
- Alsaggaf Mohammed Ubaid
- Alser Osaid H.
- Alshareef Reham
- Altaf Abdulmalik
- Altamimi Abdullah
- Altamimi Afnan
- Altamini Afnan
- Altarayra Marwa
- Althwainy Amani
- Altibi Ahmed
- Altinel Yuksel
- Altoe Fernanda
- Altwigry Abdulrahman M.
- Altwijri Abdulaziz
- Alvarez Ismael Isaac Zelada
- Alvi Abdul Rehman
- Alwafai Mohammad Ghassan
- Aly Abouelatta Khairy
- Aly Mohammed Yahia Mohamed
- Alyacoubi Said
- Alyahya Reem
- Alyami Rifan
- AlYoussef Ibrahim
- Alzahrani Ahmed
- Alzahrani Mohammed
- Alzayat Thuraya
- Aman Nowrin F.
- Amandito Radhian
- Ambrozeviciute Viktorija
- Ameen Mohamed
- Amer Mohamed A
- Amin Hager Abdul Aziz
- Amin Jasim
- Amin Shadid Al
- Amjad Mohammadasim
- Ammar Mohamed
- Ammar Mohamed Sabry
- Amoah Michael
- Amoako Joachim
- Amoako Philip Taah
- Amoako-Boateng Mabel
- Amole Isaac
- Amreia Mahmoud
- Anderson-Knight Hannah
- Andersson Linda
- Andika Ferry Fitriya Ayu
- Andreotti Dario
- Angelieri Daniele
- Anis Echaieb
- Ansaloni Luca
- Antar Sarah
- Antezana Diego
- Anthoulakis Christos
- Antoniozzi Angelo
- Anwar Abdul Wahid
- Anwar Nourhan
- Anwer Wahid
- Anyanwu Lofty-John
- Aonzo Paolo
- Appeadu-Mensah William
- Appiah Eric Kofi
- Aql Shaimaa
- Aquilino Fabrizio
- Arachchi Prasad Pitigala
- Arachchige Lalith Asanka Jayasooriya Jayasooriya
- Arafa Omar
- Arafa Sara
- Arango Maria Clara Mendoza
- Araujo Rafael
- Arcudi Claudio
- Ardley Rohan
- Arenas Andy
- Aristizã¡bal Fred Alexander Naranjo
- Arman Sam
- Armellini Andrea
- Arnaud Alexis Pierre
- Arshad Mohammad Mohsin
- Arsyad Hasbi Maulana
- Arthur Tom
- Arulampalam Tan
- Aruldas Neerav
- Asal Mohamed
- Asar Yomna Hosny
- Asare-Bediako Kwasi
- Asele Frehun Ayele
- Ashal Gehad El
- Ashour Ahmad
- Ashour Khlood
- Ashtari Morvarid
- Ashton Annelisse
- Asi Fatema
- Asilah Siti Mohd Desa
- Assal Abdelrahman
- Assouto Pamphile A
- Asturias Sabrina
- Asumah Hamza
- Ata Ahmed
- Ata Ali Amin Ahmed
- Ata Aya Yehia
- Atiyeh Anwar
- Atkins Ebenezer Takyi
- Atkinson Kieran
- Atobatele Kazeem
- Attallah Noura A.
- Attar Samaa Mahmoud Al
- Attard Myranda
- Attia Attia
- Attia Attia Mohamed
- Augestad Knut Magne
- Aung Kyaw Phyo
- Austraite Aiste
- Aviles Susan
- Avoka Anthony
- Awad Israa
- Awad Sawsan Adel
- Awuku-Asabre Joseph
- Awwad Saad Al
- Ayad Sara
- Ayandipo Omobolaji O
- Ayyar Shruti
- Aziz Dayang Nita Abdul
- Aziz Mohamed Rezal Abdul
- Aziz Nora Abdul
- Azizeldine Mohammed G.
- Azmitia José René Arévalo
- Azzie Georges
- Azzis Olivier
- Baba Suleiman
- Bachri Houda
- Badawy Mahmoud
- Badenjki Mohamed Adel
- Badr Ahmed
- Badr Mohamed Fawzy Mahrous
- Badwi Nermin M
- Badwi Nermin Mohamed
- Badwy Assmaa
- Bahar Suraya
- Baheeg Mohamad
- Bailey Karen
- Baird Alan
- Bakhaidar Mohamad
- Bakr Ahmad
- Bakry Hesham Mohammed
- Bala Miklosh
- Balalis Dimitrios
- Baldacchino Matthew
- Balducci Genoveffa
- Balila Reem Mohammed Hassan
- Balkan Ali Zeynel Abidin
- Ball Alasdair
- Ballouhey Quentin
- Balmaceda Rubén
- Balogun Fatai
- Baltrunas Robertas
- Baluch Fatima
- Bamicha Anastasia
- Bamicha Athanasia
- Banaitis Vincas Jonas
- Bandoh Dickson
- Bani-Sadar Ahmad
- Banipal Gurpreet Singh
- Baraka Heba
- Barakat Sara Abd Elmageed
- Barendegere Venerand
- Barkolias Christos
- Barnabas Gandau Naa
- Barneo Luis
- Barrantes Ana Maria Sandoval
- Barrawi Fayez Elian Al
- Barreda Luis Miguel Alvarez
- Barrientos Linda Alvi Madrid
- Barrios Emanuel
- Barrios Emmanuel
- Basilicò Silvia
- Basir Elissa Rifhan Mohd
- Bassem Monica
- Bassit Khalil Abdul
- Basso Celeste Del
- Basso Stefano M. M
- Bastawis Fatema Al
- Basto Carlos Alejandro Arroyo
- Bautista Ana Cecilia Manchego
- Beasley William
- Bedada Alemayehu Ginbo
- Bediako-Bowan Antoinette
- Behar Nebil
- Beisa Virgilijus
- Bekhet Amira Hassan
- Bekhet Nada Mohamed
- Beleño Alvaro Enrique Mendoza
- Belkouchi Abdelkader
- Belli Andrea
- Bello Bashir
- Benammi Sarah
- Benevento Angelo
- Bennai Redouane Mammar
- Bentounsi Zineb
- Benyaiche Chaymae
- Bermúdez Ysabel Esthefany Alejos
- Berti Stefano
- Bertuello Isaac
- Beuran Mircea
- Bezzina Maureen
- Bhangu Aneel
- Bhat Sriram
- Bhatnagar Ankur
- Bhopal Kamran Faisal
- Bianco Federica
- Bigaran Annamaria
- Billy Matthew
- Birindelli Arianna
- Birring Amerdip
- Björklund Ida
- Blanco Ruth
- Blencowe Natalie
- Bliksøen Marte
- Blower Emma
- Boakye-Yiadom Kwaku
- Bocchetti Tommaso
- Bode Chris
- Bode Christopher
- Boijsen Magnus
- Bonavia Karl
- Bonavina Luigi
- Bondin John
- Bondurri Andrea
- Boni Davide De
- Boni Silvia
- Bonnard Arnaud
- Bonney William
- Bono Phoebe De
- Borda-Luque Giuliano
- Borg Elaine
- Borin Eva
- Bortolasi Luca
- Botero Jaime Andres Montoya
- Botes Stefan
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- Zachariades Dimitris-Christos
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zalabia Mohamed F
- Zamarin Kresimir
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zardab Ali
- Zegarra Sergio
- Zerihun Abebe Bekele
- Zhang Zhongtao
- Zheng Fei
- Zidan Hagar
- Zidan Mohamed
- Ziff Oliver
- Zil-E-Ali Ahsan
- Zohair Ahmed
- Zuber Markus
- Zulkifli Athirah
- Žilinskas Justas
- Žilinskienė Reda
- Žiubrytė Greta
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Background There is a substantial gap in provision of adequate surgical care in many low- and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
Prospective observational cohort study on grading the severity of postoperative complications in global surgery research
- Author
- Abayasinghe Chamika
- Abbas Muntadhar
- Abbott T. E. F.
- Abbott Tom
- Abdullah Noor Hairiza
- Abdur-Rahman Lukman
- Abeloos Jacques
- Abernethy Caroline
- Abidin Ucu Nurhadiat
- Abrunhosa Alexandra
- Absar Mohammed
- Adam Suwayba
- Adams George
- Adamson Michael
- Adekola Oyebola
- Adelaja Yemi
- Ademola Adeyinka
- Adenekan Anthony
- Adenike Odewabi
- Adeolu Augustine A
- Adetoye Adedapo
- Adewale Badru
- Adigun Tinuola
- Adolfsson Anne
- Aflori Laura
- Africander Cucu
- Afshari Arash
- Agarwal Vandana
- Agodirin Olayide
- Aguzzoli Crisitiano
- Ahmad Abdurrahman
- Ahmad Norfaizan
- Ahmad T.
- Ahmad Tahania
- Ahmad Yousra
- Ahmed Ahmed
- Ahmed Jamil
- Ahmed Tahania
- Ai Yanqiu
- Aignatoaie Mariana
- Aimoniotou-Georgiou Eleni
- Akanmu Olanrewaju
- Akerman Nik
- Akinwale Mukaila
- Al Amri Khalid
- Al Hussaini Sabah
- Al-Soudaine Yassr
- Aladin Hafiz
- Alagbe-Briggs Olubusola
- Albaj Safauldeensalem
- Alcock David
- Alcock Liam
- Aldecoa Cesar
- Aldecoa Cesar
- Aleixo Fábia Berganton
- Alexander Hazel
- Alexander Maini
- Alexander-Sefre Farhad
- Alherz Fadhel
- Ali Hani
- Ali Marlynn
- Ali Sarah
- Alias Abdul Hafiz
- Alias Anita
- Alias Raja Liza Raja
- Allen Samantha
- Allen Sara Jane
- Allison Joanna
- Alloj Chiara
- Allorto Nikki Leigh
- Allsop Joanne
- Almeida William
- Alonso Eduardo
- Alonso José Ignacio
- Alphonsus Christella
- Alvares Danielle
- Alves Maria Joao
- Amador Juan Carlos Bravo
- Ameer Yusuf
- Amendola Cristina Prata
- Ami Noam
- Amstrup-Hansen Louise
- Anagnou Athina
- Andersen Cheme
- Anderson Charlotte
- Anderson Colette
- Anderson Frank
- Anderson Philip
- Andreadaki Evangelia
- Andreou Alexandros
- Andreou Prematie
- Andrew Alyson
- Andrews Emma
- Angel Miguel Paludi
- Angermair Stefan
- Angus Kirsty
- Anillo Victor
- Anizi Mashel Al
- Antal Oana
- Antill Philip
- Antoniadou Eleni
- Apagaki Eymorfia
- Apostolou Konstantinos
- Applewhaite Christopher
- Applewhaite Christopher
- Aquino Laura Patricia González
- Ar Praburaj
- Araujo Daniela Marques
- Arawwawala Dilshan
- Ardern Diane
- Argue Ruth
- Aribawa Mahaalit Alit
- Arkalaki Eleni
- Armaganidis Apostolos
- Armstrong John
- Armstrong Richard
- Arnaoutoglou Christina
- Arnaoutoglou Elena
- Arnold Glenn
- Arrandale Lindsay
- Arrich James
- Arrigo Mario
- Arshad Homa
- Arshad Mohammed Asif
- Artiles Tania Socorro
- Arumugam Swarna
- Arustei Mirela
- Arvaniti Kostoula
- Arvaniti Kostoula
- Arya Aryabiantara
- Arya Shobhit
- Asimakos Andreas
- Aslam M
- Asudo Felicia
- Athanasakis Elias
- Atiku Mamuda
- Attrill Elizabeth
- Attwood Clare
- Auer Patrick
- Avidan Michael
- Avila Erendira Jocelin Dominguez
- Avis Joanne
- Awad Hadi
- Axioti Elena
- Azam Ummi Azmira Ahmad
- Azambuja Pedro
- Azevedo Caroline
- Aziz Faizal Zuhri
- Baas Peter
- Baghirzada Leyla
- Bai Hui-Ping
- Baillie Shelley
- Baines Duncan
- Baio Thalissa Hermínia
- Bairaktari Aggeliki
- Baker Gerard
- Baker Katie-Anne
- Baker Paul
- Balain Birender
- Balajonda Naraida
- Balanescu Andreea
- Balasubramaniam Madhu
- Baldisserotto Sérgio
- Baldwin Jacqueline
- Baldwin Matthew
- Balfoussia Danai
- Bali Christina
- Bandeira Maria Expedito
- Banerjee Robin
- Bankewitz Carla
- Banner-Goodspeed Valerie
- Bao Qi
- Barcraft-Barnes Helena
- Barneto Lisa
- Barnett Andrew
- Barraclough James
- Barras Jean-Pierre
- Barrett Stephen
- Barrett Wendy Joan
- Basanth Sujith
- Batchelor Nick
- Bateman Brian
- Bates Alexander
- Bates Sarah
- Batista Hugo Dias
- Bauchmuller Kris
- Bauer Marlene
- Baumgarten Georg
- Baxter Linden
- Beaton Ceri
- Beattie Scott
- Beattie Scott
- Beattie Scott
- Beavis Vanessa
- Beavis Vanessa
- Bechan Sudha
- Beer Johan
- Bejia Tarek
- Belciu Ioana
- Belda Margarita Tormo
- Bell Gillian
- Bell Rachel
- Bell Rachel
- Bell Stephanie
- Bellandi Mattia
- Bello Jibril
- Beloeil Helene
- Belskiy Vladislav
- Beltran Anna Valle
- Ben-Menachem Erez
- Benavent Pau
- Benevento Angelo
- Bengeri Sheshagiri
- Bennett Cambell
- Bennett Michael
- Bennett Rachael
- Bennett Victoria
- Bentley Conor
- Beretta Luigi
- Berg Andrew
- Berg Bianca
- Bergin Colin
- Bernard Andre
- Bernard Andre
- Bernard Andre
- Bernat Maria Jose
- Berntsen Emer
- Berntsen Emer
- Bertram Wendy
- Bester Delia
- Bester Marlet
- Bettega Fernanda
- Bettinelli Alessandra
- Bhardwaj Neeraj
- Bhatia Kailash
- Bhula Chettan
- Bi Yanbing
- Biais M.
- Biais Matthieu
- Biais Matthieu
- Biccard Bruce
- Biccard Bruce M
- Bidd Heena
- Bidd Heena
- Bidgoli Jawad
- Biffen Andrew
- Bignami Elena
- Bilolikar Anjali
- Birch Julie
- Bishop David Gray
- Biyase Thuli
- Bizios Christol
- Blackwell Clare
- Blackwood Douglas
- Blaj Mihaela
- Blakemore Stephen P
- Bland Martin
- Blunt Mark
- Blyth Katharine
- Bocchino Speranza
- Bodansky Daniella
- Bodger Phoebe
- Boer Christa
- Boer Hans Donald
- Boereboom Catherine
- Boggiano Victoria
- Bokkel-Andela Janneke
- Bolaji Benjamin
- Bolton David
- Boone Myles
- Boschi Luca
- Boshier Piers
- Botes Marisa
- Botis Ioannis
- Bottini Corrado
- Bottrill Fiona
- Bouchez Stefaan
- Boulton Kerenza
- Bouris Vasilios
- Bourner Lynsey
- Boutsikos Georgios
- Bouwman Arthur
- Bouwman Arthur
- Bowrey Sarah
- Boxall Leigh
- Boyd Christine
- Bradburn Mike
- Bradburn Mike
- Bradley Jacqueline
- Branagan Graham
- Branco Teresa
- Brand Bastiaan
- Brandsborg Birgitte
- Breitenstein Stefan
- Brennan Andrew
- Brennan Emma
- Brenner Laura
- Brincat Maximilian
- Briscoe Richard
- Bristogiannis Sotirios
- Brooke Jenny
- Brookes Jamie
- Brookes Morag
- Brooks Carolyn
- Broomby Rupert
- Brotto Ana Flavia
- Brown Andrew
- Brown Caroline Wrey
- Brown Gemma
- Brown Jamie
- Brown Janette
- Brown Lynne
- Brown Richard
- Brown Robyn
- Browning Julie
- Bruma Dana
- Brunete Tamara
- Brunswicker Annemarie
- Bryant Helen
- Bua Emmanuel
- Buccimazza Ines
- Buckley Sarah
- Buerkle Christian
- Buhre Wolfgang
- Buhre Wolfgang
- Builu Pierre Monji
- Buise Marc
- Bullock Clare
- Bunwarie Bimalshakth
- Burns Karen
- Burrows Lorna
- Burrows Tom
- Burston Ben
- Burtenshaw Andrew
- Burton Megan
- Busuioc Mihai
- Butryn Izabella
- Butt Georgina
- Byrne Kelly
- Bührer Thomas
- Cabezuelo Estefania
- Cabral Raquel
- Cabrini Luca
- Cacala Sharon
- Cai Fang
- Cai Yunfei
- Cain Helen
- Cairns Carel
- Cakova Veronika
- Calderwood Claire
- Callaghan Mark
- Campbell Debbie
- Campbell Doug
- Campbell Doug
- Campbell Douglas
- Campbell Gill
- Campbell Graham
- Campbell Kathleen
- Campbell Marta
- Campbell Tara
- Campey Lorraine
- Campos Ferreira Mariana Fosch
- Camsooksai Julie
- Cancho David
- Candido Keulle
- Cang Jing
- Cannavo Maurizio
- Cao Jianqiao
- Cao Ying
- Cao Zhongming
- Cardellino Silvano
- Cardosa Jorge
- Cardoso Gutemberg
- Cardy Jon
- Carmino Livio
- Carp Cristina Paula
- Carr Adrienne
- Carrera Ronald
- Carroll Christine
- Carroll Jo
- Caser Eliana
- Castaño Beatriz
- Castle Gail
- Castro Gabriel Isaac Pereira
- Cavanagh Sarah
- Cawthorn Louise
- Cernea Daniela Denisa
- Chaddock Mark
- Chaloulis Panagiotis
- Chan Alexander
- Chan Hey Man Heymans
- Chan Mathew
- Chan Matthew
- Chan Matthew
- Chan Peter
- Chan Vincent
- Chan Wai Kit Jacky
- Chan Weng Ken
- Chan Yik Lam
- Chande Shiv
- Chandler Ben
- Chandra Susilo
- Chandra Susilo
- Chandrasekharan Shardha
- Chang Yuan Hsuan
- Chaniotaki Fotini
- Charitos Efthimios
- Charlalampidoy Alexandra
- Charles Rob
- Chatterjee Devnandan
- Chatterjee Jayanta
- Chatzimichali Aikaterini
- Chau Simon
- Chazova Elena
- Cheah Clarissa
- Cheah Seleen
- Cheeseman Michelle
- Cheing Yushio
- Chen Chao
- Chen Chen
- Chen Feifei
- Chen Fumei
- Chen Hong
- Chen James
- Chen Junping
- Chen Lee-lynn
- Chen Lee-lynn
- Chen Linbi
- Chen Liyong
- Chen Pushan
- Chen Qiang
- Chen Rong
- Chen Shasha
- Chen Shiyu
- Chen Sijia
- Chen Yaqiu
- Chen Yijiao
- Chen Yijun
- Chen Yongjie
- Chen Zhang
- Cheng Baoli
- Cheng Ka Ho
- Cherian Ritchie
- Cherrett Veronica
- Chetty Rubendraj R
- Chew Michelle
- Chew Michelle
- Chhabra Ashok
- Chicken Dennis-Wayne
- Chilinciuc Ion
- Chin Im Im
- Chirkut Subash
- Chlorou Dimitra
- Choi Hyun-min David
- Choi Stephen
- Chow Lorraine
- Christian Rachel
- Christiansen Ida Cecilie
- Christmas Natasha
- Christodoulidis Gregory
- Christodoulopoulou Theodora
- Christofaki Maria
- Christoforidis Dimitri
- Chronis Christos
- Chu Hiu Man
- Chu Susanna
- Chua Pandora
- Chukkambotla Srikanth
- Chung Chun Kwong Eric
- Cifra Elna
- Ciobanu Cristina
- Ciobotaru Oana Roxana
- Cirstea Emanuel
- Clark Richard
- Clarkson Aisling
- Clavien Pierre-Alain
- Claxton Andrew
- Clemmons Karen
- Cloro Luigi Maria
- Clyde Antony
- Cobzaru Isabelle
- Codita Anisoara
- Colangelo Antonio
- Colangelo Chiara
- Colling Kerry
- Collins Michelle
- Collins Nwokoro
- Colvin Carolyn
- Commey Thelma
- Comptaer Nicolas
- Conceição Soares Maria
- Conde Carlos
- Conradie Alae
- Constantin Kathryn
- Cook Tim
- Cooper Lauren
- Cooper Lucy
- Cooper Mariese
- Cooper Richard
- Cooper Sarah
- Copaciu Elena
- Cope Jennifer
- Copley Edward
- Copotoiu Sanda Maria
- Coppens Marc
- Corneci Dan
- Cornell Jonathan
- Cornish Julie
- Corti Daniele
- Costa Fischer Bruna Ferreira
- Costa Ana Cristina Miranda Martins
- Costanzo Eleonora
- Costelloe Hannah
- Cotter Rochelle
- Cotterell Sharon
- Cotterill Donna
- Coughlan Elaine
- Coulter Ian
- Coulter Suzanne
- Coutinho Francisco
- Cowton Amanda
- Cox Hannah
- Cozar Octavian Ionut
- Craig Jayne
- Craven Rachael
- Craw Nicholas
- Craw Sarah
- Creary Thais
- Cripps Heather
- Critchley Rebecca
- Cronje Larissa
- Cruickshank Ross
- Cruikshanks Andrew
- Cruz Salome
- Cuenca Vicente Chisbert
- Cueva Andreu
- Cunha Pedro
- Currow Helen
- Currow Helen
- Czepanski Carolyn
- Czeslick Elke
- Cádiz Maria José Hernández
- D'Andrea Rocco
- Dafnios Nikolaos
- Dai Qingqing
- Dai Qinxue
- Dai Si Yuan
- Daikou Panagoula
- Dalamagka Maria
- Dalampini Eleftheria
- Dali-Kemmery Lola
- Dalton Emma
- Damant Rose
- Daniel Conway
- Daniel Gayatri Daniel
- Daniel Harvey
- Daniel Hull
- Daniel Sonya
- Darko Julia
- Darwish Sharif
- Das Suparna
- Dasrath Ashish
- Datson Amanda
- Daubeny Thomas
- Daugaard Morten
- Davari Maria
- Dave Tejal
- Davies Charlotte
- Davies Helen
- Davies Keith
- Davies Kirsty
- Davies Leigh
- Davies Zoe
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- Davis Simon
- Daya Bhavika
- De Andres Jose
- De Baerdemaeker Luc
- De Bruyne Ann
- De Hert Stefan
- De Jongh Karen
- De Kegel Dirk
- De Meyer Jenine N
- De Oliveira Mirella Cristine
- Deacon Matthew
- Deblaere Isabel
- Dedemadi Georgia
- Deen Tariq
- Deepak Shantal
- Deighton Kerry
- Deja Maria
- Del Valle Santiago Garcia
- Delgado García David R
- Demartines Nicolas
- Dempsey Ged
- Dempster Angie
- Denham Samuel
- Dent Kathy
- Dermitzaki Despina
- Desbordes Jacques
- Despotidis Vasileios
- Diaconescu Ciresica
- Diago Lorena Gómez
- Dias Fernando
- Dias Sandra
- Dickson Jane
- Ditai James
- Ditai James
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- Donovan Andrew
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- Doumos Rodamanthos
- Downes Charlotte
- Doyle Donna
- Dragnea Dragos
- Dragoescu Nicoleta Alice
- Drake Matthew
- Drimala Maria
- Drinkwater Zoe
- Drummond Leanne
- Du Fang
- Du Fang
- Du Xindan
- Duarte Célia
- Dube Nokukhanya Z
- Duca Alejandro
- Dudgeon Lucy
- Dudson Rosie
- Duivenvoorde Yoni
- Dumitrascu Clementina Oana
- Dumitrescu Alexandra
- Dunay Artem
- Dunk Nigel
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- Durodola Adekunle
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- Durst Alexander
- Duttchen Kaylene
- Dutu Madalina
- Dwyer Heather
- Dylst Dimitri
- Dzhamullaev Parvin
- Dzulkipli Norizawati
- Echem Richard
- Edmond Holly
- Edwards Jayne
- Edwards Marc
- Edwards Mark
- Efthymiadi Andromachi
- Egan Thomas
- Eggleston Christopher
- Eichwalder Andreas
- Eikman Johan
- Ekelund Kim
- El-Sayed Ahmed
- Elabib Ali
- Elferink-Vonk Renske
- Ellis Jessica
- Ellis Kate
- Elna Cifra
- Emma Temlett
- Eneje Philip
- Eng Kristen
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- English Rose
- Epodoi Joseph
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- Evans Chris
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- Everingham Kirsty
- Ewe Renee
- Ezekiel Emmanuel
- Ezike Humphrey
- Faina Lais
- Falk Elke
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- Fan Lihua
- Fan Yu
- Fanfani Lucia Caterina
- Fang Xiangming
- Faponle Folayemi
- Faria Filomena
- Farid Nahla
- Farina Zane
- Farrell Helen
- Farrow Mehreen
- Fasina Oluyemi
- Fatungase Oluwabunmi Motunrayo
- Faulds Matthew
- Fei Yue
- Fellinger Paul
- Feng Yunlin
- Fengas Lior
- Fergey Lauren
- Ferguson Marissa
- Fernández Salvador
- Ferrando Carlos
- Filipescu Daniela
- Filippopoulos Andreas
- Finch Amanda
- Fiorentza Klara
- Fischbach Norbert
- Flatt Jim
- Fleischer Andreas
- Fleisher Lee
- Fleisher Lee
- Fleisher Lee A.
- Flores Armando Adolfo Alvarez
- Flores Kathrina
- Flossos Andreas
- Foers William
- Foglia Julena
- Foley Julia
- Foley Julia
- Fonck Kristine
- Foord Denise
- Foot Helen
- Foot Jayne
- Ford David
- Forget Patrice
- Forsans Emma
- Forstner Karin
- Foster Rebecca
- Foubert Luc
- Fouracres Anna
- Fowler Alexander
- Fowler Carolyn
- Fraga Julia Merladete
- Fragandreas George
- Franklin John
- Franks Romilla
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- Freeman David
- Freeman Victoria
- Freethy Alexander
- Freitas Katie
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- Freschini David
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- Fritsch Gerhard
- Frost Victoria
- Fu Kaiwen
- Fu Shuying
- Fu Yunbin
- Fuad Akram
- Fuentes Isabel
- Fulton Graham
- Funk Bonita
- Funk Duane
- Furrer Markus
- Futier E.
- Futier Emmanuel
- Futier Emmanuel
- Gaitanakis Stylianos
- Gall Lewis
- Gallacher Pete
- Gallard Sian
- Gallego Laura
- Gama N Sibusiso
- Gambhir Rajiv
- Ganter Donna Louise
- Ganter Michael T
- Gao Hong
- Garcia Carolina Soledad Romero
- Garcia Juliana
- Garcia-Saiz Irene
- García-Pérez Maria Luisa
- Gardikou Varvara Vanessa
- Gardiner Matthew
- Garg Atul
- Garg Sameer
- Garg Sanjeev
- Garrett Emily
- Gasperi Julia
- Gastaldi Christian
- Gatta Alessandro
- Gaudin Christophe
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- Gbolahan Olalere
- Ge Xiaodong
- Geddoa Burair
- Geddoa Emad
- Geddoa Emad
- Geisen Martin
- Geldenhuys Jacques
- Gemert Ankie Koopman-van
- Geng Wujun
- Georgakakis Georgios
- George Ronald
- George Ronald
- George Ronald
- Georgiou Georgios
- Georgopoulou Eleni
- Gercek Yuksel
- Germann Reinhard
- Geromarkaki Elisavet
- Ghafar Fara Nur Idayu Abd
- Ghignone Federico
- Ghosh Alison
- Ghushe Neil
- Giancarlo Luigi
- Giannaki Chrysavgi
- Gibson-Lapsley Hannah
- Giles Julian
- Gill James
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- Gillespie David
- Gillies Michael
- Gilmore Jemma
- Gilmour Fiona
- Gkini Konstantia-Paraskevi
- Gkiokas Georgios
- Gkioni Panagiota
- Gkonezou Elena
- Glasbey James
- Glasgow Emma
- Glister Georgina
- Glover Lyn
- Goad Ehab Helmy Abdel
- Goebel Ulrich
- Goga Ismail E
- Goga Riaz
- Goldberg Olivia
- Golder Kim
- Gondo Prisca
- Gonzalez Alba Perez
- Gordon Paul
- Goss Harry
- Gouws Hanni
- Govender Komalan
- Govindasamy Vishendran
- Grace Anuforo
- Gracia Estefania
- Granum Simon Nørgaard
- Graterol Juan
- Gratrix Karen
- Graves Lynne
- Gray Carol
- Gray Catherine
- Gray Sophie
- Greaves K. E.
- Greaves Rosanna
- Green Garyth M
- Green-Thompson Randolph
- Greene Michael
- Gregory Peter
- Grey Ben
- Griffiths Ewen
- Grigoras Ioana
- Grigoryev Evgeny
- Grintescu Ioana
- Grishkowez Elena
- Grocott Mike
- Grosu Ramona-Mihaela
- Grubmueller Karl Gernot
- Gudaca Mariethel
- Guimarães Mario
- Guizeline Jaqueline
- Gunn Jacqueline
- Guo Baolei
- Guo Fengying
- Guo Huinan
- Guo Yongqing
- Guo Zheng
- Guok Eng Ching
- Gupta Ajay
- Guttenthaler Vera
- Guy Kramer
- Gätke Mona Ring
- Habicher Marit
- Hack Yvonne
- Haddow J.
- Haddow James
- Hadebe Bernard
- Hadfield Daniel
- Hadi Husni Zaeem Abd
- Hagau Natalia
- Haigh Kathryn
- Hales Dawn
- Hall Andrew Macalister
- Hall Kathryn
- Hall Richard
- Hall Richard
- Hall Roger
- Halliwell Richard
- Halliwell Richard
- Hambidge Oliver
- Hamdan Alhafidz
- Hamilton Caroline
- Hamzah Zulkarnain
- Han Kunyuan
- Han Yangyang
- Handayani Dini
- Harden Catherine
- Hare Gregory
- Hariharan Vimal
- Harrichandparsad R
- Harries Rhiannon
- Harris Benjamin
- Harris Clair
- Harris James
- Harris Meredyth
- Harris Rudy
- Harris Sarah
- Harrison Jonathan
- Harsan Cristian Remus
- Hartmann Cristina
- Haselberger Simone
- Hatton Jonathan
- Haunch Kirsty
- Hawes Elizabeth
- Hawkins Lesley
- Hay David
- Hayes Morgan Philip
- He Changlin
- He Jie
- He Long
- He Miao
- He Xin
- Heather Blaylock
- Hedin Annika
- Hedin Annika
- Heintzelmann Simon Bisgaard
- Helen Bryant
- Hellewell Alistair
- Helliwell Laurence
- Hellstrom Johanna
- Helmy Naeder
- Hennings Charles
- Hering Jens Peter
- Hernandez Carlos B
- Hernandez Miguel
- Hert Stefan
- Hesketh Sue
- Hewson Russ
- Hewson Russell
- Heyse Bjorn
- Hicks Catherine
- Hidayatullah Rahmat
- Hiesmayr Michael
- Higgie Kushlin
- Hill Gillian
- Hill Simon
- Hillermann Thomas
- Hills Vicky
- Hinther Ashley
- Hinther Ashley
- Hinxman Honor
- Hitchcock Rachael
- Hoare Siobhan
- Hobrok Maria
- Hodgkiss Tracey
- Hodgson Richard E
- Hodzovic Emil
- Hoedt Marielle
- Hoeft Andreas
- Hoeft Andreas
- Hofer Christoph
- Hofer Christoph
- Hoffer Franz
- Hoffmann João
- Holaubek Caroline
- Holden Douglas
- Hollands Heidi
- Holliger Stephan
- Hollmann Markus
- Holmes Kerry
- Holmström Sandra
- Holt Peter
- Hong Bosun
- Hood Marion
- Hopkins Brian
- Hopkins Luke
- Hopkins Thomas
- Horn Rachel
- Hosdurga Gurunath
- Hou Benchao
- Hou Jiabao
- Houston Kendra
- Houweling Peter
- Hove Mazvangu Onie
- Hovendal Claus
- Hu Liu
- Hu Na
- Hu Nianqiang
- Hu Rong
- Hu Shuangfei
- Hu Tingju
- Hu Xianwen
- Hu Xiaolan
- Hu Xuming
- Huang Changshun
- Huang Ledan
- Huang Lixia
- Huang Luping
- Huang Song
- Huang Wenhui
- Huang Yanming
- Hubner Martin
- Hughes Thomas
- Hugill Keith
- Hulme Jonathan
- Hulst Abraham
- Humphreys Sally
- Humphries Ryan
- Hung Ching Yue Janice
- Hunt Jane
- Husain Tauqeer
- Hussain Ayyaz
- Hussain Nabilah
- Hutchings Melanie
- Hutchins David
- Hutton Monica
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- Xiong Xiapei
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- Xu Guan-Jie
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- Yang Yang
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- Yao Yurui
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- Yeh Erlinda
- Yin Ning
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- Yun Bai
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- Zamudio Diana
- Zangrillo Alberto
- Zapata Darcy Danitza Mari
- Zbitnew Geoff
- Zeggeren Laura
- Zeidan Lisa
- Zeng Qiuting
- Zettergren Jan
- Zhang Baoling
- Zhang Enman
- Zhang Huaigen
- Zhang Huan
- Zhang Jie
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- Zhang Mingxiao
- Zhang Qin
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- Zhang Shihai
- Zhang Weiwei
- Zhang Xiaoguang
- Zhang Xiaolin
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- Zhang Ye
- Zhang Yuan
- Zhao Bing
- Zhao Bo
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- Zhao Jiashi
- Zhao Jinning
- Zhao Lei
- Zhao Shuna
- Zhao Ting
- Zhao Weihong
- Zhao Weilu
- Zhao Xiaoying
- Zhen Jungang
- Zheng Kang
- Zheng Lina
- Zheng Tianzhao
- Zhong Yi
- Zhou Ce
- Zhou Dachun
- Zhou Haidong
- Zhou Haiyan
- Zhou Jiali
- Zhou Jialong
- Zhou Jing
- Zhou Xian-jin
- Zhu Xiaomao
- Zhu Yi
- Zhu Zhipeng
- Zhuang Xiuxiu
- Zilis Georgios
- Zin Nor Hafizah Mohd
- Zingerle Nicolette
- Zingg Urs
- Zoerner Frank
- Zonneveldt Harry
- Zou Xiaohua
- Zoulamoglou Menelaos
- Zsisku Lajos
- Zundert Tom
- Zyl Rebekka
- åkring Irene
- Ögren Katrin
- Publication venue
- 'Wiley'
- Publication date
- 22/10/2018
- Field of study
Background
The Clavien–Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. However, it is unclear whether the Clavien–Dindo system can be used internationally in studies across differing healthcare systems in high- (HICs) and low- and middle-income countries (LMICs).
Methods
This was a secondary analysis of the International Surgical Outcomes Study (ISOS), a prospective observational cohort study of elective surgery in adults. Data collection occurred over a 7-day period. Severity of complications was graded using Clavien–Dindo and the simpler ISOS grading (mild, moderate or severe, based on guided investigator judgement). Severity grading was compared using the intraclass correlation coefficient (ICC). Data are presented as frequencies and ICC values (with 95 per cent c.i.). The analysis was stratified by income status of the country, comparing HICs with LMICs.
Results
A total of 44 814 patients were recruited from 474 hospitals in 27 countries (19 HICs and 8 LMICs). Some 7508 patients (16·8 per cent) experienced at least one postoperative complication, equivalent to 11 664 complications in total. Using the ISOS classification, 5504 of 11 664 complications (47·2 per cent) were graded as mild, 4244 (36·4 per cent) as moderate and 1916 (16·4 per cent) as severe. Using Clavien–Dindo, 6781 of 11 664 complications (58·1 per cent) were graded as I or II, 1740 (14·9 per cent) as III, 2408 (20·6 per cent) as IV and 735 (6·3 per cent) as V. Agreement between classification systems was poor overall (ICC 0·41, 95 per cent c.i. 0·20 to 0·55), and in LMICs (ICC 0·23, 0·05 to 0·38) and HICs (ICC 0·46, 0·25 to 0·59).
Conclusion
Caution is recommended when using a treatment approach to grade complications in global surgery studies, as this may introduce bias unintentionally
The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis
- Author
- Ab Majid Mohd Azuan
- Ab Rahman Ahmad Sufian
- Ab Rahman Rusnah
- Abayasinghe Chamika
- Abbas Muntadhar
- Abbott T. E. F.
- Abbott Tom
- Abd Ghafar Fara Nur Idayu
- Abd Hadi Husni Zaeem
- Abdel Goad Ehab Helmy
- Abdullah Noor Hairiza
- Abdur-Rahman Lukman
- Abeloos Jacques
- Abernethy Caroline
- Abidin Ucu Nurhadiat
- Abrunhosa Alexandra
- Absar Mohammed
- Adam Suwayba
- Adams David
- Adams George
- Adamson Michael
- Adekola Oyebola
- Adelaja Yemi
- Ademola Adeyinka
- Adenekan Anthony
- Adenike Odewabi
- Adeolu Augustine A.
- Adetoye Adedapo
- Adewale Badru
- Adigun Tinuola
- Adolfsson Anne
- Africander Cucu
- Afshari Arash
- Agarwal Vandana
- Agodirin Olayide
- Aguzzoli Crisitiano
- Ahamed khader null
- Ahmad Azam Ummi Azmira
- Ahmad Abdurrahman
- Ahmad Norfaizan
- Ahmad T.
- Ahmad Tahania
- Ahmad Yousra
- Ahmed Ahmed
- Ahmed Jamil
- Ahmed Tahania
- Ai Yanqiu
- Aignatoaie Mariana
- Aimoniotou-Georgiou Eleni
- Akanmu Olanrewaju
- Akerman Nik
- Akinwale Mukaila
- Al Anizi Mashel
- Al hussaini Sabah
- Al'Amri Khalid
- Al-Soudaine Yassr
- Aladin Hafiz
- Alagbe-Briggs Olubusola
- Albaj Safauldeensalem
- Alberto Lisi Zaheer Moolla
- AlbertoVolta Carlo
- Alcock David
- Alcock Liam
- Aldecoa Cesar
- Aleixo Fábia Berganton
- Alexander Hazel
- Alexander Maini
- Alexander-Sefre Farhad
- Alherz Fadhel
- Ali Hani
- Ali Marlynn
- Ali Sarah
- Alias Abdul Hafiz
- Alias Anita
- Alit Mahaalit Aribawa
- Allen Samantha
- Allen Sara Jane
- Allison Joanna
- Alloj Chiara
- Allorto Nikki Leigh
- Allsop Joanne
- Almeida William
- Alonso Eduardo
- Alonso José Ignacio
- Alphonsus Christella
- Alvares Danielle
- Alves Maria Joao
- Amador Juan Carlos Bravo
- Ameer Yusuf
- Amendola Cristina Prata
- Ami Noam
- Amstrup-Hansen Louise
- Anagnou Athina
- Andersen Cheme
- Anderson Charlotte
- Anderson Colette
- Anderson Frank
- Anderson Philip
- Andreadaki Evangelia
- Andreou Alexandros
- Andreou Prematie
- Andrew Alyson
- Andrews Emma
- Angermair Stefan
- Angus Kirsty
- Anillo Victor
- Antal Oana
- Antill Philip
- Antoniadou Eleni
- Antonina Webombesa
- Apagaki Eymorfia
- Apostolou Konstantinos
- Applewhaite Christopher
- Aquino Laura Patricia González
- Ar Praburaj
- Arawwawala Dilshan
- Ardern Diane
- Argue Ruth
- Arkalaki Eleni
- Arlo whitehouse null
- Armaganidis Apostolos
- Armstrong John
- Armstrong Richard
- Arnaoutoglou Christina
- Arnaoutoglou Elena
- Arnold Glenn
- Arrandale Lindsay
- Arrich James
- Arrigo Mario
- Arshad Homa
- Arshad Mohammed Asif
- Artiles Tania Socorro
- Arumugam Swarna
- Arustei Mirela
- Arvaniti Kostoula
- Arya Aryabiantara
- Arya Shobhit
- Asimakos Andreas
- Aslam F Noorbhai M.
- Asudo Felicia
- Athanasakis Elias
- Atiku Mamuda
- Attrill Elizabeth
- Attwood Clare
- Auer Patrick
- Avidan Michael
- Avila Erendira Jocelin Dominguez
- Avis Joanne
- Awad Hadi
- Axioti Elena
- Azambuja Pedro
- Azevedo Caroline
- Aziz Faizal Zuhri
- Baas Peter
- Baghirzada Leyla
- Bai Hui-Ping
- Bai Yun
- Baillie Shelley
- Baines Duncan
- Baio Thalissa Hermínia
- Bairaktari Aggeliki
- Baker Gerard
- Baker Katie-Anne
- Baker Paul
- Balain Birender
- Balaji Packianathaswamy
- Balajonda Naraida
- Balanescu Andreea
- Balasubramaniam Madhu
- Baldisserotto Sérgio
- Baldwin Jacqueline
- Baldwin Matthew
- Balfoussia Danai
- Bali Christina
- Bandeira Maria Expedito
- Banerjee Robin
- Bankewitz Carla
- Banner-Goodspeed Valerie
- Bao Qi
- Barcraft-Barnes Helena
- Barneto Lisa
- Barnett Andrew
- Baroselli Antonio
- Barraclough James
- Barras Jean-Pierre
- Barrett Stephen
- Barrett Wendy Joan
- Basanth Sujith
- Batchelor Nick
- Bateman Brian
- Bates Alexander
- Bates Sarah
- Batista Hugo Dias
- Bauchmuller Kris
- Bauer Marlene
- Baumgarten Georg
- Baxter Linden
- Beaton Ceri
- Beattie Scott
- Beavis Vanessa
- Beavis Vanessa
- Bechan Sudha
- Bejia Tarek
- Belciu Ioana
- Belda Margarita Tormo
- Bell Gillian
- Bell Rachel
- Bell Stephanie
- Bellandi Mattia
- Bello Jibril
- Beloeil Helene
- Belskiy Vladislav
- Beltran Anna Valle
- Ben-Menachem Erez
- Benavent Pau
- Benedikt Preckel Osne Kirzner
- Benevento Angelo
- Bengeri Sheshagiri
- Bennett Cambell
- Bennett Michael
- Bennett Rachael
- Bennett Victoria
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- Beretta Luigi
- Berg Andrew
- Bergin Colin
- Bernard Andre
- Bernat Maria Jose
- Berntsen Emer
- Bertram Wendy
- Bester Delia
- Bester Marlet
- Bettega Fernanda
- Bettinelli Alessandra
- Bhardwaj Neeraj
- Bhatia Kailash
- Bhula Chettan
- Bi Yanbing
- Biais Matthieu
- Biccard B. M.
- Biccard Bruce
- Biccard Bruce M.
- Bidd Heena
- Bidgoli Jawad
- Biffen Andrew
- Bignami Elena
- Bilolikar Anjali
- Bin Mustapha Mohd Tarmimi
- Birch Julie
- Bishop David Gray
- Biyase Thuli
- Bizios Christol
- Blackwell Clare
- Blackwood Douglas
- Blaj Mihaela
- Blakemore Stephen P.
- Bland Martin
- Blunt Mark
- Blyth Katharine
- Bocchino Speranza
- Bodansky Daniella
- Bodger Phoebe
- Boer Christa
- Boereboom Catherine
- Boggiano Victoria
- Bogner Gerhard
- Bokkel-Andela Janneke ten
- Bolaji Benjamin
- Bolton David
- Boone Myles
- Boschi Luca
- Boshier Piers
- Botes Marisa
- Botis Ioannis
- Bottini Corrado
- Bottrill Fiona
- Bouchez Stefaan
- Boulton Kerenza
- Bouris Vasilios
- Bourner Lynsey
- Boutsikos Georgios
- Bouwman Arthur
- Bowrey Sarah
- Boxall Leigh
- Boyd Christine
- Bradburn Mike
- Bradley Jacqueline
- Branagan Graham
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- Brenner Laura
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- Briscoe Richard
- Bristogiannis Sotirios
- Brooke Jenny
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- Brown Richard
- Brown Robyn
- Browning Julie
- Bruma Dana
- Brunete Tamara
- Brunswicker Annemarie
- Bryant Helen
- Bua Emmanuel
- Buccimazza Ines
- Buckley Sarah
- Buerkle Christian
- Buhre Wolfgang
- Builu Pierre Monji
- Buise Marc
- Bullock Clare
- Bunwarie Bimalshakth
- Burns Karen
- Burrows Lorna
- Burrows Tom
- Burston Ben
- Burtenshaw Andrew
- Burton Megan
- Busuioc Mihai
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- Butt Georgina
- Byrne Kelly
- Bührer Thomas
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- Cabrini Luca
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- Cai Fang
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- Cancho David
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- Cang Jing
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- Cao Ying
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- Cardellino Silvano
- Cardosa Jorge
- Cardoso Gutemberg
- Cardy Jon
- CarmenVaida Laura Aflori
- Carmino Livio
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- Carr Adrienne
- Carrera Ronald
- Carroll Christine
- Carroll Jo
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- Castle Gail
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- Chaddock Mark
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- Chan Yik Lam
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- Chandrasekharan Shardha
- Chang Yuan Hsuan
- Chaniotaki Fotini
- Charitos Efthimios
- Charlalampidoy Alexandra
- Charles Rob
- Chatterjee Devnandan
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- Chatzimichali Chatzimichali Aikaterini
- Chau Simon
- Chazova Elena
- Cheah Clarissa
- Cheah Seleen
- Cheeseman Michelle
- Cheing Yushio
- Chen Chao
- Chen Chen
- Chen Feifei
- Chen Fumei
- Chen Hong
- Chen James
- Chen Junping
- Chen Lee-lynn
- Chen Linbi
- Chen Liyong
- Chen Pushan
- Chen Qiang
- Chen Rong
- Chen Shasha
- Chen Shiyu
- Chen Sijia
- Chen Yaqiu
- Chen Yijiao
- Chen Yijun
- Chen Yongjie
- Chen Zhang
- Cheng Baoli
- Cheng Ka Ho
- Cheng Zhonggui
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- Zhang Min
- Zhang Mingxiao
- Zhang Qin
- Zhang Ruilin
- Zhang Shihai
- Zhang Weiwei
- Zhang Xiaoguang
- Zhang Xiaolin
- Zhang Xiaoyan
- Zhang Xuekang
- Zhang Yan
- Zhang Yapping
- Zhang Ye
- Zhang Yuan
- Zhao Bing
- Zhao Bo
- Zhao Chong
- Zhao Jiashi
- Zhao Jinning
- Zhao Lei
- Zhao Lili
- Zhao Shuna
- Zhao Ting
- Zhao Weihong
- Zhao Weilu
- Zhao Xiaoying
- Zhen Jungang
- Zheng Kang
- Zheng Lina
- Zheng Tianzhao
- Zhong Yi
- Zhou Ce
- Zhou Dachun
- Zhou Haidong
- Zhou Haiyan
- Zhou Jiali
- Zhou Jialong
- Zhou Jing
- Zhou Xian-jin
- Zhu Xiaomao
- Zhu Xiaoping
- Zhu Yi
- Zhu Zhipeng
- Zhuang Xiuxiu
- Zilis Georgios
- Zingerle Nicolette
- Zingg Urs
- Zoerner Frank
- Zonneveldt Harry
- Zou Xiaohua
- Zoulamoglou Menelaos
- Zsisku Lajos
- Åkring Irene
- Ögren Katrin
- Publication venue
- Health Sciences Research Commons
- Publication date
- 30/10/2017
- Field of study
© 2017 British Journal of Anaesthesia Background: The surgical safety checklist is widely used to improve the quality of perioperative care. However, clinicians continue to debate the clinical effectiveness of this tool. Methods: Prospective analysis of data from the International Surgical Outcomes Study (ISOS), an international observational study of elective in-patient surgery, accompanied by a systematic review and meta-analysis of published literature. The exposure was surgical safety checklist use. The primary outcome was in-hospital mortality and the secondary outcome was postoperative complications. In the ISOS cohort, a multivariable multi-level generalized linear model was used to test associations. To further contextualise these findings, we included the results from the ISOS cohort in a meta-analysis. Results are reported as odds ratios (OR) with 95% confidence intervals. Results: We included 44 814 patients from 497 hospitals in 27 countries in the ISOS analysis. There were 40 245 (89.8%) patients exposed to the checklist, whilst 7508 (16.8%) sustained ≥1 postoperative complications and 207 (0.5%) died before hospital discharge. Checklist exposure was associated with reduced mortality [odds ratio (OR) 0.49 (0.32–0.77); P\u3c0.01], but no difference in complication rates [OR 1.02 (0.88–1.19); P=0.75]. In a systematic review, we screened 3732 records and identified 11 eligible studies of 453 292 patients including the ISOS cohort. Checklist exposure was associated with both reduced postoperative mortality [OR 0.75 (0.62–0.92); P\u3c0.01; I2=87%] and reduced complication rates [OR 0.73 (0.61–0.88); P\u3c0.01; I2=89%). Conclusions: Patients exposed to a surgical safety checklist experience better postoperative outcomes, but this could simply reflect wider quality of care in hospitals where checklist use is routine
Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries
- Author
- A T Landers
- Aaron Lawson McLean
- Abbey Paton
- Abdel Razzaq Khalaf
- Abdul Hafiz Alias
- Abdurrahman Ahmad
- Abegail Salvana
- Abigail Keen
- Abigail Patrick
- Abraham Hulst
- Acela G Lopez
- Adam Evans
- Adam Rehak
- Adamu Muhammad Sarki
- Ade Nurkacan Dursin
- Ade Susanti
- Adela Ruiz
- Adeline Rankin
- Ademola Talabi
- Adenekan Adetoye
- Adeoluwa Tayo
- Adeyinka Ademola
- Aditi Kulkarni
- Aditi Naik
- Aditi Shrivastava
- Adriana Krepil
- Adrianna Woolsey
- Adrianna Woolsey
- Adrienne Carr
- Afolabi Owojuyigbe
- Aggeliki Bairaktari
- Agoritsa Tsioka
- Agostino Roasio
- Ahamed Khader
- Ahmad Sufian Ab Rahman
- Ahmed Ahmed
- Ahmed El-Sayed
- Ahmed Saloojee
- Ahmed Sayeed
- Aida Tantri
- Aida Tantri
- Aikaterini Chatzimichali
- Aikaterini Kyparissi
- Aikaterini Makatounaki
- Aisling Clarkson
- Ajay Gupta
- Akanmu Durodola
- Akbar Vohra
- Akbar Vohra
- Akbar Vohra
- Akbar Vohra
- Akram Fuad
- Alae Conradie
- Alasdair Scott
- Alastair Rose
- Alba Perez Gonzalez
- Albert Tsui
- Alberto Lisi
- Alberto Premoli
- Alberto Ramirez
- Alberto Zangrillo
- Alda Martins
- Aleaxandra Moustaka
- Alejandra Romero Rodrigo
- Alejandro Duca
- Alejandro Suarez-de-la-Rica
- Aleksandr Iurin
- Aleksandr Molkov
- Aleksandr Samoilenko
- Aleksandr Tchekulaev
- Alessandra Bettinelli
- Alessandro Gatta
- Alessandro Marchesi
- Alex Looseley
- Alex Ragan
- Alexander Bates
- Alexander Chan
- Alexander Durst
- Alexander Fowler
- Alexander Freethy
- Alexander Ishimaru
- Alexander Kulikov
- Alexander Tolmasov
- Alexandra Abrunhosa
- Alexandra Charlalampidoy
- Alexandra Dumitrescu
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- Richard More
- Richard Roach
- Richard Spencer-Jones
- Richard Thomas
- Richard von Rhaden
- Richard Wassall
- Rini Najoan
- Rita Moor
- Ritchie Cherian
- Rizwana Malik
- Roana Donohue
- Rob Charles
- Rob Spanjersberg
- Robert Johnson
- Robert Maril
- Robert Walker
- Robert Wise
- Roberta Meroni
- Robin Banerjee
- Robyn Brown
- Rocco D'Andrea
- Rochelle Cotter
- Rodamanthos Doumos
- Rodrigo Souza Rodrigues
- Roel Matos-Puig
- Roger Hall
- Roger Schmid
- Rohan Prakash
- Romilla Franks
- Ronald Carrera
- Ronald George
- Ronald George
- Ronald George
- Rondall Lane
- Ronelle Mouton
- Rong Chen
- Rong Hu
- Roopa McCrossan
- Rory Riddell
- Rosanna Greaves
- Rosanna Varden
- Rose Damant
- Rose English
- Roshan Rao
- Rosie Dudson
- Ross Cruickshank
- Ross Kennedy
- Ross Kerridge
- Rotimi Peter Olonisakin
- Rubendraj R Chetty
- Rubeshan Naidoo
- Rudy Harris
- Rui Freitas Mendonça Correia da Silva
- Rui Moreno
- Rui Moreno
- Rui Xue
- Ruilin Zhang
- Rune Sarauw Lundsgaard
- Rupert Broomby
- Rupert M Pearse
- Rupert M. Pearse
- Rusnah Ab Rahman
- Russ Hewson
- Russell Hewson
- Ruth Argue
- Ruvashni Naidoo
- Ryan Humphries
- Ryan Salter
- Sabah Al Hussaini
- Sabine Ethgen
- Safauldeensalem Albaj
- Sahayam Santa
- Sahely Flores Risco
- Saiful Aizar Kesut
- Sailaja Pothuneedi
- Sailaja Pothuneedi
- Salim Tayeh
- Sally Anne Pearson
- Sally Humphreys
- Sally Wright
- Salome Cruz
- Salvador Fernández
- Sam Montasser
- Sam Papadopoullos
- Samantha Allen
- Samantha Keenan
- Sameer Garg
- Sameer Somanath
- Samir Patel
- Samson Tou
- Samuel Denham
- Sanda Maria Copotoiu
- Sandeep Varma
- Sandra Dias
- Sandra Holmström
- Sandra Jumbe
- Sanghamitra Mishra
- Sanjay Shah
- Sanjeev Garg
- Santiago Garcia Del Valle
- Saoirse Lyons
- Sara Jane Allen
- Sara Lyckner
- Sara Pick
- Sara Pick
- Sara Rêgo
- Sara Scott
- Sarah Ali
- Sarah Bates
- Sarah Bowrey
- Sarah Buckley
- Sarah Cavanagh
- Sarah Cooper
- Sarah Craw
- Sarah Harris
- Sarah James
- Sarah Mills
- Sarah Moreton
- Sarah Rasip
- Sarah Scourfield
- Sarah Welsh
- Sarah Williams
- Satwant Gill
- Satwant Kaur
- Saul Sundayi
- Saul Velaz Dominguez
- Savino Spadaro
- Scott Beattie
- Scott Beattie
- Scott Beattie
- Scott Nicol
- Sean Mcmullan
- Sebastian Tranca
- Seigne Richard
- Seleen Cheah
- Selina Sewpersad
- Semarawima Wima
- Serge Molliex
- Sergey Puzanov
- Sergi Tormo
- Shafa Ullah
- Shailendra Sham
- Shalil Solanki
- Shan Luo
- Shane McQuoid
- Shanglong Yao
- Shantal Deepak
- Shara McDonald
- Shardha Chandrasekharan
- Sharif Darwish
- Sharon Cacala
- Sharon Cotterell
- Shasha Chen
- Shashikant Yegnaram
- Shaun Naidoo
- Sheba Predeep
- Shelley Baillie
- Sheng Wang
- Shenhui Jin
- Shenhui Wang
- Sheraz Markar
- Sherezade Tovar Doncel
- Sheshagiri Bengeri
- Sheshendrasurian Visvalingam
- Shihai Zhang
- Shilpaja Karpate
- Shirley Pyke
- Shiv Chande
- Shiva Tripathi
- Shiva Tripathi
- Shixia Xu
- Shiyu Chen
- Shobhit Arya
- Shu Kai Ma
- Shuangfei Hu
- Shuangjia Yang
- Shuchi Kaushik
- Shuchun Yu
- Shuijing Wu
- Shun Wang
- Shuna Zhao
- Shuying Fu
- Si Yuan Dai
- Sian Gallard
- Sian Thomas
- Sibongile J Mothae
- Siegfried Veit
- Siew Ching Tan
- Sigismond Lasocki
- Sijia Chen
- Silvano Cardellino
- Silvia Martín
- Silvia Sanchez-Morcillo
- Simao Esteves
- Simeon Olateju
- Simon Bisgaard Heintzelmann
- Simon Chau
- Simon Davis
- Simon Hill
- Simon Large
- Simon Lawson
- Simon Lewthwaite
- Simon Nørgaard Granum
- Simon Pickard
- Simon Varley
- Simona Margarit
- Simone Haselberger
- Sindiswa Ntloko
- Sinead Kelly
- Siobhan Hoare
- Sofia Kokkini
- Sofia Marques
- Sofia Serra
- Solange R Nahum
- Somasundaram Jeyanthan
- Song Huang
- Sonia Sampson
- Sonja Meier
- Sonya Daniel
- Sophia Tsiligiannis
- Sophie Gray
- Sophie Mathoulin
- Sotannde Sola
- Sotirios Bristogiannis
- Sotirios Georgios Popeskou
- Speranza Bocchino
- Spyros Zakynthinos
- Srikanth Chukkambotla
- Stanislav Pugachev
- Stavros Tsampalas
- Stefaan Bouchez
- Stefan Angermair
- Stefan Breitenstein
- Stefan de Hert
- Stefan De Hert
- Stefan Wildi
- Stephan Holliger
- Stephan Thilen
- Stephanie Bell
- Stephanie Jones
- Stephen Barrett
- Stephen Choi
- Stephen John Roberts
- Stephen Kowalski
- Stephen P Blakemore
- Stephen Phillips
- Stephen Webb
- Stephens Robert
- Steve Rose
- Steve White
- Steven Kim
- Steven Kleopoulos
- Steven Takemoto
- Steyn van Wyk
- Stuart White
- Stylianos Gaitanakis
- Stylianos Karatzas
- Stéphane de Rudnicki
- Su Meng
- Subash Chirkut
- Sudha Bechan
- Sudheer Karlakki
- Sue Hesketh
- Sue Olliff
- Suhas Kumar
- Sujith Basanth
- Sukhada Savarkar
- Sukumar Nagaiah
- Suman Mewa Kinoo
- Sumara Niman
- Sumayer Sanghera
- Sumitra Lahiri
- Suneetha Venugopal
- Sunny Karadia
- Suparna Das
- Suren R Ramphal
- Susan Melbourne
- Susan Smolen
- Susanna Chu
- Susanne Sonnemann
- Susanne Sonnemann
- Susilo Chandra
- Susilo Chandra
- Suwayba Adam
- Suzana Lobo
- Suzana M Lobo
- Suzanne Coulter
- Suzanne Odeberg-Wernerman
- Svenja Pabel
- Swarna Arumugam
- Swarna Baskar Sharma
- Swati Karmarkar
- Swati Pande
- Sze Meng Wong
- Sérgio Baldisserotto
- Søren Hübertz Smith
- Taeyang Kim
- Tahania Ahmad
- Tahania Ahmed
- Talvinder Gill
- Tamara Brunete
- Tamas Szakmany
- Tamas Szakmany
- Tanaka Muzenda
- Tania Socorro Artiles
- Tara Campbell
- Tara Walker
- Tarek Bejia
- Tariq Deen
- Tatiana Lefaki
- Tatiana Slepova
- Tauqeer Husain
- Tejal Dave
- Temlett Emma
- Tengku Alini Tengku Lih
- Teresa Branco
- Teresa Rotunno
- Terry Martin
- Tesuven K Naidu
- Thais Creary
- Thalissa Hermínia Baio
- Thandinkosi E Madiba
- Thelma Commey
- Theodora Christodoulopoulou
- Theodora Melissopoulou
- Theodosios Theodosopoulos
- Theoniki Paraforou
- Theonymfi Papavasilopoulou
- Theophilos Rozenberg
- Thiago Motta Netto
- Thinagrin Dhasarthun Naidoo
- Thomas Bührer
- Thomas Daubeny
- Thomas Egan
- Thomas Hillermann
- Thomas Hopkins
- Thomas Hughes
- Thomas Jared McCormick
- Thomas Jared McCormick
- Thomas Mayrhofer
- Thomas McCormick
- Thomas Mencke
- Thomas Owen
- Thomas Parsons
- Thomas Smith
- Thuli Biyase
- Tiago do Nascimento Cabral
- Tian Yu
- Tianlong Wang
- Tianqin Yang
- Tianzhao Zheng
- Tim Cook
- Tim Short
- Timothy Jones
- Timothy McCulloch
- Timothy Salmond
- Tina Kobborg
- Ting Zhao
- Tingju Hu
- Tinuolac Adigun
- Tjokorda Gde Agung Senapathi
- Tokunbo Olajumoke
- Tom Abbott
- Tom Burrows
- Tom Jacobs
- Tom Jowitt
- Tom Lawson
- Tom Lawton
- Tom van Zundert
- Tonia Onyeka
- Tony Smith
- Tony Wong
- Tracey Hodgkiss
- Tracey Lowery
- Tracey Nolan
- Tracey Nolan
- Tracey Roberts
- Tracy Lam
- Tracy Norton
- Tracy-Lee Jansen
- Tressy Pitt-Kerby
- Troy Wildes
- Tse Siang Tan
- Tunde Osinaike
- Ucu Nurhadiat Abidin
- Ulf Kessler
- Ulrich Goebel
- Ulrika Winstone
- Uma Shastri
- Umar Musa Sule
- Ummi Azmira Ahmad Azam
- Urs Zingg
- Utara Hartawan Utara
- Vaia Aliki Rompou
- Valentin Tutunaru
- Valentina Paola Plumari
- Valentina Testa
- Valentina Tulupova
- Valerie Banner-Goodspeed
- Valerie Serra Maudet
- Valerie Smit-Fun
- Valeriy Levin
- Vandana Agarwal
- Vanessa Beavis
- Vanessa Beavis
- Vanessa Beavis
- Vanessa Nesbitt
- Varvara Vanessa Gardikou
- Vasileia Nyktari
- Vasileios Despotidis
- Vasileios Kalles
- Vasileios Ourailoglou
- Vasilios Bouris
- Vasilios Koulouras
- Veerle Van Mossevelde
- Vera Guttenthaler
- Veronica Cherrett
- Veronika Cakova
- Vicari Sottosanti
- Vicente Chisbert Cuenca
- Vicky Hills
- Victor Anillo
- Victor Aspelund Liljequist
- Victor Ionita
- Victor Raji
- Victoria Bennett
- Victoria Boggiano
- Victoria Freeman
- Victoria Frost
- Victoria Lambourne
- Victoria Martinson
- Victoria Phelps
- Vieri Parrini
- Vikas Kaura
- Vilavan Koompirochana
- Vimal Hariharan
- Vincent Chan
- Vineshykaa Ramesh Kumar
- Vinícius Nascimento
- Vishal Narwani
- Vishendran Govindasamy
- Vivek Sinha
- Vivesh Rughubar
- Vlad Kushakovsky
- Vladimir Kretov
- Vladislav Belskiy
- Vukani T Manzini
- Vítor Miguel Pinho-Oliveira
- Wai Cheong Soon
- Wai Kit Jacky Chan
- Wangpin Xiao
- Warren Paul Kuhn
- Wei Ren
- Wei Xiao
- Weihong Zhao
- Weilin Sung
- Weilu Zhao
- Weiwei Zhang
- Weixing Wang
- Wendy Bertram
- Wendy Joan Barrett
- Weng Ken Chan
- Wenhui Huang
- Werner Schmid
- Werner Schmid
- Weslley Mendes
- Widnyana Made Wid
- William Almeida
- William Foers
- William Peat
- Wilson Binh Quan Huynh
- Wilson Fabio Serna Martínez
- Wilton van Klei
- Wing LamWong
- Wing Sze Li
- Wing Yan Lam
- Wiryana Made Wir
- Wolfgang Buhre
- Wolfgang Buhre
- Wujun Geng
- Xenia Souvatzis
- Xian-Jin Zhou
- Xianfu Lu
- Xiangming Fang
- Xianwen Hu
- Xiao Hong Wen
- Xiaocui Lv
- Xiaodong Ge
- Xiaodong Qiu
- Xiaoguang Zhang
- Xiaohua Zou
- Xiaolan Hu
- Xiaolin Zhang
- Xiaomao Zhu
- Xiaoqin Li
- Xiaoyan Zhang
- Xiaoying Li
- Xiaoying Zhao
- Xiaoyu Li
- Xiaoyun Shi
- Xiapei Xiong
- Xin He
- Xindan Du
- Xinjian Lu
- Xinmei Jiang
- Xinyu Qi
- Xiu-Li Wang
- Xiumei Song
- Xiuxiu Zhuang
- Xuewu Lin
- Xuming Hu
- Yan Jing
- Yan Leng
- Yan Pan
- Yan Zhang
- Yana Ilyina
- Yanbing Bi
- Yanfei Xia
- Yang Liu
- Yang Yang
- Yangwen Ou
- Yangyang Han
- Yanling Li
- Yanming Huang
- Yanqiu Ai
- Yapping Zhang
- Yaqi Li
- Yaqiu Chen
- Yassr Al-Soudaine
- Yavor Metodiev
- Yazhou Wen
- Yazhuo Yuan
- Ye Zhang
- Yelong Ren
- Yemi Adelaja
- Yetong Li
- Yew Ching Lee
- Yi Liu
- Yi Zhong
- Yi Zhu
- Yijiao Chen
- Yijun Chen
- Yik Lam Chan
- Ying Cao
- Yingfen Xiong
- Yingping Liang
- Yixiu Yan
- Yiyi Shi
- Yonghao Yu
- Yongjie Chen
- Yongqing Guo
- Yongtao Sun
- Yongzhong Tang
- Yoni van Duivenvoorde
- Youliang Tong
- Yousif Saeed
- Yousra Ahmad
- Yu Fan
- Yu Sun
- Yuan Hsuan Chang
- Yuan Liang Woon
- Yuan Zhang
- Yuanming Pan
- Yuanyuan Pan
- Yue Fei
- Yuehong Qi
- Yuejiang Liu
- Yuelan Wang
- Yugang Shi
- Yuhong Li
- Yuksel Gercek
- Yun Bai
- Yun Ren
- Yunbin Fu
- Yunchang Mo
- Yunfei Cai
- Yunlin Feng
- Yunzhi Ling
- Yurui Yao
- Yushio Cheing
- Yusuf Ameer
- Yuting Wang
- Yves Jaquet
- Yvonne Hack
- Yvonne Selibea
- Zaheer Moolla
- Zaid Makzal
- Zane Farina
- Zhang Chen
- Zhen Dan Peng
- Zhen Wang
- Zhen Wang
- Zheng Guo
- Zhengyuan Liu
- Zhenrong Ji
- Zhi Wang
- Zhipeng Wang
- Zhipeng Zhu
- Zhisong Li
- Zhiting Wen
- Zhong-Yuan Xia
- Zhongming Cao
- Zi-Ying Shen
- Zin Nico
- Ziqiang Miao
- Zoe Davies
- Zoe Drinkwater
- Zoe Whitman
- Zulkarnain Hamzah
- Álvaro Réa-Neto
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
This was an investigator initiated study funded by Nestle Health Sciences through an unrestricted research grant, and by a National Institute for Health Research (UK) Professorship held by RP. The study was sponsored by Queen Mary University of London