Affordable, Energy-Efficient Housing Design for Chile: Achieving Passivhaus Standard with the Chilean State Housing Subsidy

In Chile, it is estimated that the energy demand will continue to increase if substantial energy efficiency measures in housing are not taken. These measures are generally associated with technical and mainly economic difficulties. This paper aims to show the technical and economic feasibility of achieving Passivhaus standard house in Chile, considering the budget of the maximum state subsidy currently available (Chilean Unidad de Fomento (CLF) 2000 ≈ 81,000 USD). The design was simulated in the Passive House Planning Package software to determine if the house could be certified with the selected standard. At the same time, the value of all the items was quantified in order not to exceed the stipulated maximum budget for a house considered as affordable. It was shown that in terms of design it is possible to implement the Passivhaus standard given the current housing subsidy. The designed housing ensures a reduction of 85% in heating demand and a 60% reduction in CO2 emissions during the operation, compared to an average typical Chilean house

Pathological and normal variability of foot bones in osteological collections from Catalonia (Spain) and Lazio (Italy)

A wide number of factors can affect the structure of the bones in the foot. In bioarchaeology, few studies about foot anomalies include population comparisons and changes across time. We aimed to identify normal and pathological variability that affected the foot in the recent history of West Mediterranean populations. Thus, we analyzed change in occurrence of rare variants, pathological lesions, entheseal morphology, and their probable causes. We studied 518 pairs of skeletonized feet dated from the 2nd–20th centuries CE, from Catalonia (Spain) and the region of Lazio (Italy). Moreover, a Neolithic series from Oman has been analyzed for contrast. We found that calcaneal spur, hypertrophic peroneal trochlea of calcaneus, periosteal reaction of talar neck, alteration of articular surface to lateral cuneiform, displaced talar neck to medial plane, osteophytes in cuneiform-navicular joint, fused phalanges, and forefoot eburnation showed significant differences among countries. Contrasting by countries and dates, we noticed an increase in the frequencies of these variables from Spain over the centuries. Conversely, there are no temporal differences among the Italian series. The period encompassing the 10th–19th centuries CE demonstrated the highest differences between countries. Lifestyle, occupations, footwear, and geography could be the origin of variability

Pattern and process in Amazon tree turnover, 1976-2001

Previous work has shown that tree turnover, tree biomass and large liana densities have increased in mature tropical forest plots in the late twentieth century. These results point to a concerted shift in forest ecological processes that may already be having significant impacts on terrestrial carbon stocks, fluxes and biodiversity. However, the findings have proved controversial, partly because a rather limited number of permanent plots have been monitored for rather short periods. The aim of this paper is to characterize regional-scale patterns of 'tree turnover' (the rate with which trees die and recruit into a population) by using improved datasets now available for Amazonia that span the past 25 years. Specifically, we assess whether concerted changes in turnover are occurring, and if so whether they are general throughout the Amazon or restricted to one region or environmental zone. In addition, we ask whether they are driven by changes in recruitment, mortality or both. We find that: (i) trees 10 cm or more in diameter recruit and die twice as fast on the richer soils of southern and western Amazonia than on the poorer soils of eastern and central Amazonia; (ii) turnover rates have increased throughout Amazonia over the past two decades; (iii) mortality and recruitment rates have both increased significantly in every region and environmental zone, with the exception of mortality in eastern Amazonia; (iv) recruitment rates have consistently exceeded mortality rates; (v) absolute increases in recruitment and mortality rates are greatest in western Amazonian sites; and (vi) mortality appears to be lagging recruitment at regional scales. These spatial patterns and temporal trends are not caused by obvious artefacts in the data or the analyses. The trends cannot be directly driven by a mortality driver (such as increased drought or fragmentation-related death) because the biomass in these forests has simultaneously increased. Our findings therefore indicate that long-acting and widespread environmental changes are stimulating the growth and productivity of Amazon forests

Genomic Expression Analysis Reveals Strategies of Burkholderia cenocepacia to Adapt to Cystic Fibrosis Patients' Airways and Antimicrobial Therapy

Pulmonary colonization of cystic fibrosis (CF) patients with Burkholderia cenocepacia or other bacteria of the Burkholderia cepacia complex (Bcc) is associated with worse prognosis and increased risk of death. During colonization, the bacteria may evolve under the stressing selection pressures exerted in the CF lung, in particular, those resulting from challenges of the host immune defenses, antimicrobial therapy, nutrient availability and oxygen limitation. Understanding the adaptive mechanisms that promote successful colonization and long-term survival of B. cenocepacia in the CF lung is essential for an improved therapeutic outcome of chronic infections. To get mechanistic insights into these adaptive strategies a transcriptomic analysis, based on DNA microarrays, was explored in this study. The genomic expression levels in two clonal variants isolated during long-term colonization of a CF patient who died from the cepacia syndrome were compared. One of the isolates examined, IST439, is the first B. cenocepacia isolate retrieved from the patient and the other isolate, IST4113, was obtained three years later and is more resistant to different classes of antimicrobials. Approximately 1000 genes were found to be differently expressed in the two clonal variants reflecting a marked reprogramming of genomic expression. The up-regulated genes in IST4113 include those involved in translation, iron uptake (in particular, in ornibactin biosynthesis), efflux of drugs and in adhesion to epithelial lung tissue and to mucin. Alterations related with adaptation to the nutritional environment of the CF lung and to an oxygen-limited environment are also suggested to be a key feature of transcriptional reprogramming occurring during long-term colonization, antibiotic therapy and the progression of the disease

Analysis of the Efficiency of Human Management Practices on High Technology Firm’s Performance : [вып. квалификац. работа по спец. "Менеджмент"]

The object of the study is the company ENDE ANDINA SAM. For comparison reasons, we added two companies to this research: Industrial Society Taunus S.A. and Industrial Rodriguez SRL (enterprises also that belong to the industrial sector of Bolivia).The p

Uruguayan experience with cryopreserved arterial homografts

INTRODUCTION: We analyzed the Uruguayan experience with cryopreserved arterial homografts. We studied 55 medical records in the period from June 9, 2000 to April 7, 2007, including 41 from males and 14 from females, ranging from 36-78 years of age. The clinical indications were as follows: Group 1, revascularization of infrainguinal atherosclerotic occlusive disease by bypass due to the lack of availability of a suitable vein (n = 35); Group 2, substitution of an infected prosthetic grafts (n = 15); and Group 3, arteriovenous fistula (AVF) after failure of previous prosthetic loops by repeated thrombosis and/or infection in the absence of a vein (n = 5). RESULTS: Among Group 1, primary and secondary patency rates were 61% and 71%, respectively at 1 year with 15 complications, 3 infections, 8 thromboses, 2 aneurysms, 1 homograft degradation, and 1 death related to surgery. Among Group 2, the primary and secondary patency rates were 71% and 79%, respectively, at 1 year with 6 patients experiencing complications. Group 3 did not have complications with a primary patency rate of 67% at 1 year. CONCLUSIONS: The use of cryopreserved arterial homografts is a valid, accessible, and safe alternative in complicated vascular situations. In our country, it is a technology to consider for patients with critical limb ischemia, when the risk of a major amputation is high and it is not possible to have a suitable vein or prosthetic bypass. It can be an excellent alternative for the substitution of infected synthetic bypasses, especially to substitute in situ for an infected aortic graf

One dimensional inorganic oxovanadium polymers functionalized with manganese(II) complexes: Structural and magnetic characterization

International audienceTwo organo-inorganic hybrid manganese(II) vanadates [Mn(phen)2(VO3)2]∞ (1) and [{Mn(bipy)(VO3)2}{VO2(bipy)}(VO3)(V2O6)]∞ (2) were synthesized hydrothermally. Compound 1 is a chain consisting in VO3 units propagating along the b axis, decorated with {Mn(phen)2}+2 subunits. Compound 2 is a ladder like structure propagating along the a axis, consisting of two helical chains connected by the heterobinuclear {Mn(bipy)VO4 (2,2′-bipy)} moieties, generating a double helical structure. Magnetization measurements reveal that dominant antiferromagnetic interactions are mediated between the manganese(II) centers for both structures through oxovanadate bridges. Magnetic data of compound 1 were fitted with the analytical expression for a regular chain model, estimating a J value of −0.30 cm−1. The DAVE code was use to fit experimental data and calculate the values of the super exchange constants for 2, assuming four different exchange pathways, J12 = −0.17 cm−1; J23 = −0.12 cm−1; J13 = −0.08 cm−1; J24 = −0.05 cm−1. DFT calculations on a tetranuclear fragment of 2, using diamagnetic substitutions, gave super exchange values of J12 = −17.5 cm−1 and J23 = −8.5 cm−1, corroborating the antiferromagnetic nature of the interactions as observed experimentally