413 research outputs found
Maistuuko "Sahlin olevaist"?
Kirja-arvioSivula, Jaakko: Sahlin olevaist. Lahden seudun murresanast
A population-based study of reduced sleep duration and hypertension : the strongest association may be in premenopausal women
Objectives: Recent evidence indicates that reduced sleep duration may be associated with an increased risk of hypertension with possibly stronger effects among women than men. We therefore examined cross-sectional sex-specific associations of sleep duration with hypertension in a large population-based sample from the Western New York Health Study (1996<2001).
Methods: Participants were 3027 white men (43.5%) and women (56.5%) without prevalent cardiovascular disease (median age 56 years). Hypertension was defined as blood pressure at least 140 or at least 90&mmHg or regular use of antihypertensive medication. Multivariate logistic regression analyses were performed to estimate odds ratios (ORs) of hypertension comparing less than 6&h of sleep per night versus the reference category (&6&h) while accounting for a number of potential confounders.
Results: In multivariate analyses, less than 6&h of sleep was associated with a significant increased risk of hypertension compared to sleeping at least 6&h per night, only among women [OR&=&1.66 (1.09 to 2.53)]. No significant association was found among men [OR&=&0.93 (0.62 to 1.41)].
In subgroup analyses by menopausal status, the effect was stronger among premenopausal women [OR&=&3.25 (1.37 to 7.76)] than among postmenopausal women [OR&=&1.49 (0.92 to 2.41)].
Conclusion: Reduced sleep duration, by increasing the risk of hypertension, may produce detrimental cardiovascular effects among women. The association is independent of socioeconomic status, traditional cardiovascular risk factors, and psychiatric comorbidities, and is stronger among premenopausal women. Prospective and mechanistic evidence is necessary to support causality
Making garbage collection independent of the amount of garbage
(Appendix to SICS Research Report R86009) This appendix shows in detail how to make the time for the garbage collection algorithm presented in [AHS 86] become proportional to n log n , where n is the number of non-garbage cells. It is assumed that the reader is familiar with [AHS 86] since no further presentation of the notation used is made here. The compaction phase of that algorithm is proportional to the amount of memory, i.e. proportional to the sum of garbage and non-garbage. This is unfortunate since for instance a garbage collection using copying is just proportional to the amount of non-garbage. If a program generates much more garbage than non-garbage, it might be a severe drawback of a garbage collection algorithm to depend on the amount of garbage. This paper shows how to make the garbage collection in [AHS] independent of the amount of garbage
Unpacking the "institutional portfolio" theoretical elements for an analysis of institutional change through objectification of resources and habitus
The "social kill" (Fligstein, 1997 and 2001) attributed to social entrepreneurs is ont sufficiently explicit as regards their dispositions for engaging in actions of change. After placing the status of change in the context of institutionalist literature, the author intend to show how, with the help of Pierre Bourdieu's theory of field and habitus, it is possible to develop what he call an institutional portfolio allowing a micro-individual analysis of the capacity of some individuals to undertake institutional transformations without losing sight of the evolution - at a macro-analytical level - of the structure of the field in which these individuals operate. In this respect, the author intend to contribute to the various attempts at overcoming the paradox of the "embedded agency" and to give a more precise account of institutional change.neo-institutionalism; institutional entrepreneurship; field; habitus; resources; institutional portfolio
Risk, commercialism and social purpose: Repositioning the English housing association sector
Originally seen as the âthird armâ of UK housing policy, the independent, not-for-profit housing association sector had long been seen as effective in âfilling the gapâ where the state or market were unable to provide for households in need. Since the 1980s in particular, successive governments had viewed housing associations in favourable terms as efficient, semi-autonomous social businesses, capable of leveraging significant private funding. By 2015, in contrast, central government had come to perceive the sector as inefficient, bureaucratic and wasteful of public subsidy. Making use of institutional theory, this paper considers this paradigm shift and examines the organisational responses to an increasingly challenging operating environment. By focusing, in particular, on large London housing associations, the paper analyses their strategic decision-making to address the opportunities and threats presented. The paper argues that in facing an era of minimal subsidy, low security and high risk, the 2015 reforms represent a critical juncture for the sector. Housing organisations face a stark dilemma about whether to continue a strategy of âprofit for purposeâ or to embrace an unambiguously commercial ethos. The article contends that the trajectory of decision-making (although not unidirectional) leads ultimately towards an increased exposure to risk and vulnerability to changes in the housing market. More fundamentally, the attempt to reconcile social and commercial logics is likely to have wider consequences for the legitimacy of the sector
Geertgen tot Sint Jans\u27s Night Nativity: A Study in Female Spirituality Practices
The Night Nativity by Geertgen tot Sint Jans depicts the birth of Christ in a manner that emphasizes the role of the Virgin as mother and Christ as the enlightener of the world. In this paper, I will argue that the Night Nativity was directed primarily toward meeting the devotional needs and interests of the nuns of the Convent of Our Lady of the Visitation near Haarlem. This convent is of particular interest because it is associated with the Windesheim Congregation of the Modern Devotion, which was a religious movement that privileged certain forms of lay spirituality. In particular, the adherents of the Modern Devotion seemed to have preferred various forms of affective devotion often associated with âwomenâs spirituality.â Geertgenâs image, I believe, appealed to the women in the convent because it focuses on the role of the Virgin and, in doing so, activated well-known tropes of female spirituality
A theorem-proving approach to deciding properties of finite control agents
The report presents a decision procedure for assertions in an extension of the mu-calculus about finite-control pi-calculus agents. The procedure is based on the classical cut-free sequent calculus and associated techniques of automatic theorem proving
Transnational governance through standard setting:The role of transnational communities
This chapter explores the role that community forms of social organization play in transnational standard setting. We compare the evolution of two cases through time â the International Competition Network/Community and the Creative Commons Community. Those two transnational communities exhibit quite distinct features and character. The International Competition Network has been, from the start, a selective and exclusive community bringing together public or quasi-public agencies to buttress an existing and dominant agenda. The Creative Commons community, on the other hand, emerged as a bottom-up, civil society based social movement, constructed around a challenger agenda with an inclusive grassroots philosophy. Our comparison of those two quite different cases does not uphold the expectation that different types of transnational communities would show distinctive strengths and weaknesses. Rather, we show that each of those communities deployed strategies to deal, through time, with their own particular weaknesses and that both have been quite successful in their overall objective to strengthen and spread a given standard across multiple boundaries
Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis
Introduction:
Acute metabolic acidosis of non-renal origin is usually a result of either lactic or ketoacidosis, both of which are associated with a high anion gap. There is increasing recognition, however, of a group of acidotic patients who have a large anion gap that is not explained by either keto- or lactic acidosis nor, in most cases, is inappropriate fluid resuscitation or ingestion of exogenous agents the cause.
Methods:
Plasma ultrafiltrate from patients with diabetic ketoacidosis, lactic acidosis, acidosis of unknown cause, normal anion gap metabolic acidosis, or acidosis as a result of base loss were examined enzymatically for the presence of low molecular weight anions including citrate, isocitrate, α-ketoglutarate, succinate, malate and d-lactate. The results obtained from the study groups were compared with those obtained from control plasma from normal volunteers.
Results:
In five patients with lactic acidosis, a significant increase in isocitrate (0.71 ± 0.35 mEq l-1), α-ketoglutarate (0.55 ± 0.35 mEq l-1), malate (0.59 ± 0.27 mEq l-1), and d-lactate (0.40 ± 0.51 mEq l-1) was observed. In 13 patients with diabetic ketoacidosis, significant increases in isocitrate (0.42 ± 0.35 mEq l-1), α-ketoglutarate (0.41 ± 0.16 mEq l-1), malate (0.23 ± 0.18 mEq l-1) and d-lactate (0.16 ± 0.07 mEq l-1) were seen. Neither citrate nor succinate levels were increased. Similar findings were also observed in a further five patients with high anion gap acidosis of unknown origin with increases in isocitrate (0.95 ± 0.88 mEq l-1), α-ketoglutarate (0.65 ± 0.20 mEq l-1), succinate (0.34 ± 0.13 mEq l-1), malate (0.49 ± 0.19 mEq l-1) and d-lactate (0.18 ± 0.14 mEq l-1) being observed but not in citrate concentration. In five patients with a normal anion gap acidosis, no increases were observed except a modest rise in d-lactate (0.17 ± 0.14 mEq l-1).
Conclusion:
The levels of certain low molecular weight anions usually associated with intermediary metabolism were found to be significantly elevated in the plasma ultrafiltrate obtained from patients with metabolic acidosis. Our results suggest that these hitherto unmeasured anions may significantly contribute to the generation of the anion gap in patients with lactic acidosis and acidosis of unknown aetiology and may be underestimated in diabetic ketoacidosis. These anions are not significantly elevated in patients with normal anion gap acidosis
Methanol Reformer System Modeling and Control using an Adaptive Neuro-Fuzzy Inference System approach
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