Investigation in optimisation of accuracy with non-contact systems by influencing variable processes

The use of 3D scanning systems is becoming increasingly popular and an essential tool for manufacturers for inspection and measurement. With such systems being utilised on the manufacturing shop floor due to their portability and ease of use, it is no doubt that such systems are designed to address a variety of users whom, with minimal training can operate the equipment. Due to continuing demands of high-quality products there is the need for manufacturers of 3D scanning systems to develop technologies that deliver fast and accurate information. However, one of the key challenges lies not in the training of people to use the equipment, but to develop engineers who can produce traceable, accurate and precise results with a declared statement of confidence quantifying the quality of the measurement. This statement of the quality of the output results relies on employing a set of workflow actions that involve planning, capture, processing and analysis, and finally output. This paper sets out to show how the results from a set of workflow actions from different categories of 3D scanning devices affects the quality of output

Fog and Edge Oriented Embedded Enterprise Systems Patterns: Towards Distributed Enterprise Systems That Run on Edge and Fog Nodes

Enterprise software systems enable enterprises to enhance business and management reporting tasks in enterprise settings. Internet of Things (IoT) focuses on making interactions possible between a number of network-connected physical devices. Prominence of IoT sensors and multiple business drivers have created a contemporary need for enterprise software systems to interact with IoT devices. Business process implementations, business logic and microservices have traditionally been centralized in enterprise systems. Constraints like privacy, latency, bandwidth, connectivity and security have posed a new set of architectural challenges that can be resolved by designing enterprise systems differently so that parts of business logic and processes can run on fog and edge devices to improve privacy, minimize communication bandwidth and promote low-latency business process execution. This paper aims to propose a set of patterns for the expansion of previously-centralized enterprise systems to the edge of the network. Patterns are supported by a case study for contextualization and analysis

Occupational and environmental hazard assessments for the isolation, purification and toxicity testing of cyanobacterial toxins

Cyanobacteria can produce groups of structurally and functionally unrelated but highly potent toxins. Cyanotoxins are used in multiple research endeavours, either for direct investigation of their toxicologic properties, or as functional analogues for various biochemical and physiological processes. This paper presents occupational safety guidelines and recommendations for personnel working in field, laboratory or industrial settings to produce and use purified cyanotoxins and toxic cyanobacteria, from bulk harvesting of bloom material, mass culture of laboratory isolates, through routine extraction, isolation and purification. Oral, inhalational, dermal and parenteral routes are all potential occupational exposure pathways during the various stages of cyanotoxin production and application. Investigation of toxicologic or pharmacologic properties using in vivo models may present specific risks if radiolabelled cyanotoxins are employed, and the potential for occupational exposure via the dermal route is heightened with the use of organic solvents as vehicles. Inter- and intra-national transport of living cyanobacteria for research purposes risks establishing feral microalgal populations, so disinfection of culture equipment and destruction of cells by autoclaving, incineration and/or chlorination is recommended in order to prevent viable cyanobacteria from escaping research or production facilities

UV/Optical Nuclear Activity in the gE Galaxy NGC 1399

Using HST/STIS, we have detected far-ultraviolet nuclear activity in the giant elliptical galaxy NGC 1399, the central and brightest galaxy in the Fornax I cluster. The source reached a maximum observed far-UV luminosity of \~1.2 x 10e39 ergs/s in January 1999. It was detectable in earlier HST archival images in 1996 (B band) but not in 1991 (V band) or 1993 (UV). It faded by a factor of ~4x by mid-2000. The source is almost certainly associated with the low luminosity AGN responsible for the radio emission in NGC 1399. The properties of the outburst are remarkably similar to the UV-bright nuclear transient discovered earlier in NGC 4552 by Renzini et al. (1995). The source is much fainter than expected from its Bondi accretion rate (estimated from Chandra high resolution X-ray images), even in the context of "radiatively inefficient accretion flow" models, and its variability also appears inconsistent with such models. High spatial resolution UV monitoring is a valuable means to study activity in nearby LLAGNs.Comment: 18 pages, 2 figures, 1 table; accepted for publication in Ap

A quantified triple bottom line for tourism: experimental results

The tradition of tourism businesses and regional tourism industries is to measure their value to the host community by jobs, wages and tax revenues even though every member of that community is impacted on a daily basis though a broad variety of impacts. This paper demonstrates a conceptual approach for measuring the relative importance of the major dimensions of community quality of life that can be influenced by the tourism industry in order to calculate an indication of overall impact on the well being of community residents. Furthermore, we have formulated a conjoint model that values this overall performance in monetary units. A conjoint model for estimating importance is successfully implemented using samples of college students and tourism industry professionals in the US and Cyprus. A monetary version of Triple Bottom Line impacts is calculated for the impacts of a specific hypothetical tourism business development

Fine Mapping of Genetic Variants in BIN1, CLU, CR1 and PICALM for Association with Cerebrospinal Fluid Biomarkers for Alzheimer's Disease

Recent genome-wide association studies of Alzheimer's disease (AD) have identified variants in BIN1, CLU, CR1 and PICALM that show replicable association with risk for disease. We have thoroughly sampled common variation in these genes, genotyping 355 variants in over 600 individuals for whom measurements of two AD biomarkers, cerebrospinal fluid (CSF) 42 amino acid amyloid beta fragments (Aβ42) and tau phosphorylated at threonine 181 (ptau181), have been obtained. Association analyses were performed to determine whether variants in BIN1, CLU, CR1 or PICALM are associated with changes in the CSF levels of these biomarkers. Despite adequate power to detect effects as small as a 1.05 fold difference, we have failed to detect evidence for association between SNPs in these genes and CSF Aβ42 or ptau181 levels in our sample. Our results suggest that these variants do not affect risk via a mechanism that results in a strong additive effect on CSF levels of Aβ42 or ptau181

Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection

Floral Arrangement Collaboration Sharpens Consumer Connection to Locally Grown Flowers

Our statewide floral design training program aimed to raise consumer awareness and appreciation of locally grown fresh flowers and to promote extension floral programs through delivery of workshops and demonstrations. Initially, trainees used artificial rather than fresh flowers, necessitating development of a streamlined floral design project plan. Through collaboration with three flower farmers, we developed a floral design prototype. Our growers produced the flowers based on this model and extension provided registration support and media that facilitated locally grown flowers use in workshops. As a result, we connected 47 consumers directly to our producers. Flower growers felt the project was worthwhile and desire future extension partnerships