Assessment of water quality index for the groundwater in Tumkur taluk, Karnataka state, India

The present work is aimed at assessing the water quality index (WQI) for the groundwater of Tumkur taluk. This has been determined by collecting groundwater samples and subjecting the samples to a comprehensive physicochemical analysis. For calculating the WQI, the following 12 parameters have been considered: pH, total hardness, calcium, magnesium, bicarbonate, chloride, nitrate, sulphate, total dissolved solids, iron, manganese and fluorides. The WQI for these samples ranges from 89.21 to 660.56. The high value of WQI has been found to be mainly from the higher values of iron, nitrate, total dissolved solids, hardness, fluorides, bicarbonate and manganese in the groundwater. The results of analyses have been used to suggest models for predicting water quality. The analysis reveals that the groundwater of the area needs some degree of treatment before consumption, and it also needs to be protected from the perils of contamination

4-(Benz­yloxy)phenyl 4-hexa­dec­yloxy-3-meth­oxy­benzoate

In the title compound, C37H50O5, the central benzene ring makes dihedral angles of 39.72 (14) and 64.43 (13)° with the benzyl and 3-meth­oxy­benzoate rings, respectively. The crystal structure is stabilized by inter­molecular C—H⋯π inter­actions involving the central benzene ring and the benzene ring closest to the aliphatic chain

Mobile phone based mini-spectrometer for rapid screening of skin cancer

We demonstrate a highly sensitive mobile phone based spectrometer that has potential to detect cancerous skin lesions in a rapid, non-invasive manner. Earlier reports of low cost spectrometers utilize the camera of the mobile phone to image the field after moving through a diffraction grating. These approaches are inherently limited by the closed nature of mobile phone image sensors and built in optical elements. The system presented uses a novel integrated grating and sensor that is compact, accurate and calibrated. Resolutions of about 10 nm can be achieved. Additionally, UV and visible LED excitation sources are built into the device. Data collection and analysis is simplified using the wireless interfaces and logical control on the smart phone. Furthermore, by utilizing an external sensor, the mobile phone camera can be used in conjunction with spectral measurements. We are exploring ways to use this device to measure endogenous fluorescence of skin in order to distinguish cancerous from non-cancerous lesions with a mobile phone based dermatoscope

Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning

Understanding the genomic basis of memory processes may help in combating neurodegenerative disorders. Hence, we examined the associations of common genetic variants with verbal short-term memory and verbal learning in adults without dementia or stroke (N = 53,637). We identified novel loci in the intronic region of CDH18, and at 13q21 and 3p21.1, as well as an expected signal in the APOE/APOC1/TOMM40 region. These results replicated in an independent sample. Functional and bioinformatic analyses supported many of these loci and further implicated POC1. We showed that polygenic score for verbal learning associated with brain activation in right parieto-occipital region during working memory task. Finally, we showed genetic correlations of these memory traits with several neurocognitive and health outcomes. Our findings suggest a role of several genomic loci in verbal memory processes

Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning

Understanding the genomic basis of memory processes may help in combating neurodegenerative disorders. Hence, we examined the associations of common genetic variants with verbal short-term memory and verbal learning in adults without dementia or stroke (N = 53,637). We identified novel loci in the intronic region of CDH18, and at 13q21 and 3p21.1, as well as an expected signal in the APOE/APOC1/TOMM40 region. These results replicated in an independent sample. Functional and bioinformatic analyses supported many of these loci and further implicated POC1. We showed that polygenic score for verbal learning associated with brain activation in right parieto-occipital region during working memory task. Finally, we showed genetic correlations of these memory traits with several neurocognitive and health outcomes. Our findings suggest a role of several genomic loci in verbal memory processes

Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning

Understanding the genomic basis of memory processes may help in combating neurodegenerative disorders. Hence, we examined the associations of common genetic variants with verbal short-term memory and verbal learning in adults without dementia or stroke (N = 53,637). We identified novel loci in the intronic region of CDH18, and at 13q21 and 3p21.1, as well as an expected signal in the APOE/APOC1/TOMM40 region. These results replicated in an independent sample. Functional and bioinformatic analyses supported many of these loci and further implicated POC1. We showed that polygenic score for verbal learning associated with brain activation in right parieto-occipital region during working memory task. Finally, we showed genetic correlations of these memory traits with several neurocognitive and health outcomes. Our findings suggest a role of several genomic loci in verbal memory processes.Peer reviewe

Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning

Understanding the genomic basis of memory processes may help in combating neurodegenerative disorders. Hence, we examined the associations of common genetic variants with verbal short-term memory and verbal learning in adults without dementia or stroke (N = 53,637). We identified novel loci in the intronic region of CDH18, and at 13q21 and 3p21.1, as well as an expected signal in the APOE/APOC1/TOMM40 region. These results replicated in an independent sample. Functional and bioinformatic analyses supported many of these loci and further implicated POC1. We showed that polygenic score for verbal learning associated with brain activation in right parieto-occipital region during working memory task. Finally, we showed genetic correlations of these memory traits with several neurocognitive and health outcomes. Our findings suggest a role of several genomic loci in verbal memory processes

Hydrochemical Analysis and Evaluation of Groundwater Quality in Tumkur Taluk, Karnataka State, India

Tumkur Taluk is located in the southeastern corner of Karnataka state between 13º 06'30" to 13º 31' 00" North latitude and 76º 59' 00" to 77º 19' 00" East Longitude. The Taluk spreads over an area of 1043 sq.km falling within the semiarid region and frequently facing water scarcity as well as quality problems. The major sources of employment are agriculture, horticulture and animal husbandry, engaging almost 80% of the workforce. Water samples are collected from 269 stations during pre-monsoon and 279 locations during post-monsoon of the year 2006, and were subjected to analysis for chemical characteristics. The type of water that predominates in the study area is Ca-Mg-HCO3 type during both preand post-monsoon seasons of the year 2006, based on hydro-chemical facies. Besides, suitability of water for irrigation is evaluated based on sodium adsorption ratio, residual sodium carbonate, sodium percent, salinity hazard and USSL diagram

Hydrochemical Analysis and Evaluation of Groundwater Quality in Tumkur Taluk, Karnataka State, India

Tumkur Taluk is located in the southeastern corner of Karnataka state between 13º 06\u2730" to 13º 31\u27 00" North latitude and 76º 59\u27 00" to 77º 19\u27 00" East Longitude. The Taluk spreads over an area of 1043 sq.km falling within the semiarid region and frequently facing water scarcity as well as quality problems. The major sources of employment are agriculture, horticulture and animal husbandry, engaging almost 80% of the workforce. Water samples are collected from 269 stations during pre-monsoon and 279 locations during post-monsoon of the year 2006, and were subjected to analysis for chemical characteristics. The type of water that predominates in the study area is Ca-Mg-HCO3 type during both preand post-monsoon seasons of the year 2006, based on hydro-chemical facies. Besides, suitability of water for irrigation is evaluated based on sodium adsorption ratio, residual sodium carbonate, sodium percent, salinity hazard and USSL diagram